Effect of Siryungtang, Steroid, Interferon-γand Cyclosporin-A on Mitogen Induced Interleukin-4 Activity in Minimal Change Nephrotic Syndrome

Cho, Byoung Soo 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Byoung-Soo cho. Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea. Effect of Siryungtang, Steroid, Interferon-γand Cyclosporin-A on Mitogen Interleukin4-Activity in Minimal Change Nephrotic Syndrome. Proceedings of International Symposium on East-West Medicine, Seoul. 183-186, 1999. -We have reported that patients with childhood minimal change nephrotic syndrome (MCNS) express higher levels of IL-4 mRNA expression by mitogen activated T cells using Northern blot(Cho,et al, JASN 1:518,2:590). Siryungtang(SA-1) is an oriental medicine shich has long been used in chronic renal diseases. In order to evaluate the efficacy of SA-1 on IL-4 sctivity from the monouclear cells isolated from the MCNS patients(n=5) and controls(n=5). Cells were adjusted to 2×107cells/ml with 10% FCS-RPMI and added test drugs such as SA-1, steroid(hydrocortisone, HC), CsA, IL-4& combination of SA-1+HC,SA-1+CsA&SA-1+IFN-γand mitogens(PHA-P:20㎕/ml, Con-A:20㎕/ml & PMA:50ng/ml) were added. Cells were cultured at 37℃,5% CO2 incubator for 24,48 & 72hrs. Results were as follows. 표 Mean ³[H]thymidine incorporation(cpm) was higher in controls(44,920±7,482cpm)that in patients with MCNS(30,495±2.135). However ³[H]thymidine incorporation was reduced by adding SA-1,HC, CsA & IFN-γ,or which CsA was the most effective, by combination treatment with SA-1 to steroid and CsA, significant additive effects were noted in MCNS group. In conclusion SA-1 has a steroid and CsA sparing effect and could reduce side effects of steroid and Cas significantly if clinically applicated.

Return and Volatility Spillovers in East Asian Currency Markets: A Generalized Variance Decomposition Analysis

Byoung‐,Ky Chang 한국무역학회 2013 Journal of Korea trade Vol.17 No.2

This study investigates the nature and extent of return and volatility spillovers among 10 East Asian exchange rates using the variance decomposition results from a generalized VAR and the corresponding generalized spillover index given by Diebold and Yilmaz (2012), which overcomes the drawbacks generally found in identification schemes of variance decompositions. Several results are remarkable. First, the spillovers have increased dramatically, but fluctuate periodically. The upward trend of spillovers is consistent with a continuous increase in financial market integration. Second, the return and volatility spillovers show large variability over time and are positively associated with extreme economic episodes, such as the Asian crisis of 1997, the dollar crisis of 2005, the global financial crisis of 2008‐2009, and the ongoing European debt crisis. Third, the time‐varying patterns of the return and volatility spillovers are very different across exchange rates. For example, the Korean won has been experienced the most dramatic increase in the return spillover from others, and the Singapore dollar is the most dominant net transmitter of return spillover, hence playing the role of a leader. These results have important implications for exchange rate forecast, risk management, central bank interventions and international trade.

운동실천을 위한 심리행동적 중재전략

김병준(Kim Byoung-Jun),이범기(Lee Bum Kee) 인하대학교 스포츠과학연구소 2006 스포츠과학논문집 Vol.18 No.-

본 연구는 운동이 건강에 좋다는 것을 알면서도 운동실천을 시작하지 못하는 사람들을 어떻게 운동실천을 시작하도록 하며 운동실천을 지속시킬 것인가에 대한 중재전략에 대해 선행연구들을 토대로 정리한 것이다. 운동중재(intervention)는 건강과 관련된 지식, 태도, 기준, 및 행동을 구체적인 목표를 가지고 운동을 하지 않는 사람들에게 인식시켜 운동을 시작케 하거나 운동을 지속적으로 유지시킬 목적을 가지고 건강관리 전문가로 이루어진 팀에 의해 실행되는 건강증진활동을 의미한다(Gauvin, Levesque, & Richard, 2001). 김병준(2006)은 운동실천 중재전략을 이론에 근거한 중재전략, 행동수정 전략, 인지행동전략, 내적동기 전략 등으로 구분하였다. 이론에 근거한 중재전략은 혜택인식, 방해요인 극복, 자기효능감 향상으로 운동실천을 하도록 동기유발을 일으킨다. 행동수정전략은 의사결정단서를 제공하고 출석상황을 게시하며 보상제공, 피도백 제공을 통해 운동실천을 하도록 유도한다. 인지전략으로는 목표를 현실적으로 구체적으로 제시하며 의사결정 균형표를 비교하며 운동일지 작성, 운동계약시 회원이 참여하도록 하여 책임감을 갖도록 하여 운동실천을 하도록 유도한다. 마지막으로 내적동기 전략으로 운동을 할 때에 즐거움을 체험하도록 하며 몰입상태에 임하도록 지도하여 운동실천 동기유발을 하도록 한다. 운동이 주는 긍정적인 효과를 인식하면서도 쉽게 운동실천을 시작하지 못하고 시작하더라도 오래가지 못하고 포기하고 중단하는 사람들을 다시 운동시킨다는 것은 쉬운 일은 아니다. 이러한 운동 실천을 하지 못하는 사람들을 다시금 운동실천을 하도록 동기유발을 하고 실천하도록 의지력을 갖도록 하는 것이 중요하다. 이것이 바로 운동실천을 위한 중재전략이다. The purpose of this study was to review the Intervention Strategies for increasing and keeping physical activity. The Intervention is growing of physical fitness with starting and maintenance physical activity by promotion of health expert team. Kim, byoung-Jun(2006) classed 4 theories intervention strategy. The theory authority of intervention strategy bring about motive for practicing physical activity with benefit recognition, interruption factor overcoming and self-efficacy growing. The behavior adjustment strategy induct into practice physical activity with decisional balance, attendance notice, offering of reward and offering of feedback. The knowledge strategy induct into practice physical activity with offering of detail target, comparing with decisional balance, completing sheet of physical activity and participation agreement of physical activity. Finally, internal motive strategy induct into practice physical activity with enjoyment experience. The intervention strategy for increasing physical activity is starting and maintenance physical activity who used not to practice physical activity and stop practice physical activity.

조선중기 영남사림(士林)의 원림조영 특성에 관한 연구 : 16~17세기 퇴계학파를 중심으로

박병오,양병이 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.4

Byolseo(Retreating Villa) Landscape Gardens built by the Sarim(Neo-Confucian Literati) in the middle Chosun era(16~17c) were constructed under the syntactic principles of Sung Confucianism. Especially those ones led by the Youngnam Teogye-School have some differences from those of other regions in the design language of the garden. But the previous studies on Byolseo Landscape Gardens cannot explain the microscopic characteristics, especially the periodic and regional differences. So this study is focused on the unique characteristics of Teogye-School moralists' landscape gardens. We investigated the typological characteristics of gardens including Teogye Lee's Dosanseodang and other 13 gardens of his followers in terms of design languages(patterns of location, spatial compositions and compositional elements of garden, architectural characteristics, techniques of landscape presentation). As a result of this study, it is confirmed that Teogye-School's gardens were built for their mental training and pursuing personal completion as well. But they have some authentic features different from the other region's in the garden compositions, elements, and the methods of presentation of design intentions by means of symbolized and personalized space of moral philosophy'.

안구적출에 따른 위둔덕의 칼슘결합단백질의 재구축 및 상호 연관성

안병수,고길석,안명수,김경주,권안성,정명섭,박춘매,조병옥,김진우,Samudra Acharya,Parmeshwar Narayan Amatya,장인엽 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Background: Superior colliculus is a part of midbrain, and participates in the visual reflexes, It receives afferent fibers from optic nerve, visual cortex, and spinotectal tract. After optic deprivation, the microscopic structure of the superior colliculus changed. Calcium-binding proteins (CBPs) Play an important role in the neuronal protection, differentiation and reorganization of the central nervous system, Objectives and Methods: The effects of neonatal retinal deafferentation on a CBPs, calbindm D-28k (CB), Parvalbumin (PB) and calretimn (CR), and the existence of colocalization between the CBPs were examined immunohistochemically in the rat superior colliculus. Results: On the experimental (contralateral to enucleation) side of superior colliculus, the number of CB-immunoreactive (IR) cells was reduced (77.4% compared to control), but not fibers. The number of PB-IR neurons and fibers was also reduced on the experimental side (88.5% compared to control), In the other hand, the CR-IR cells were dramatically increased (642% compared to control), but CR-IR fibers were markedly decreased on the experimental side. The colocalization between CB-CR and PV-CR was rarely observed in the superior colliculus Conclusion: These results suggest that the changes of retinotectal projection may alter the expressional pattern of CBPs in different manners; relatively stable in CB- and PV-IR neurons and plastic in CR-IR neurons.

AgTCNQ전극의 이온선택상에 미치는 전극표면상태의 영양

李炳哲,閔丙喆,孫太源 弘益大學校 科學技術硏究所 1993 科學技術硏究論文集 Vol.3 No.-

In order to compare selective characteristics of electrodeposited electrode and dipping electrode with a surface condition of electrodes, the surface of ion selective electrode have been taken a photograph by Optial Microscope and Scanning Electron Microscope, respectively. Ion selective electrode were prepared from Ag-TCNQ(7, 7, 8, 8-tetracyanoquinodimethane). The electrodes were constructed in two type methods of fabrication which were electrodeposited and dipping coated wire electrode. The electodeposited electrode was faster and smaller than dipping electrode about response rate and selectivity with respective to interferring ions. It was found that homogeneous of surface condition, formation of stable complex and thickness of electroactive materials were important factors in characterics of ion selective electrode.

수성구 관내 산·학·관·민 Win-Win 시스템

최병태,김종배,홍성준,김병상,백종현 대구산업정보대학 2001 논문집 Vol.15 No.-

Digital technical renovation and rapid development of internet and super communication technologies have dramatically influenced on trends of our society over the cyber space and college is necessary to be reformed against such current innovation to keep up with advanced technologies and skills for digital and communication fields. For this reason, initial efforts were focused on extending development of infra structraul systems to operate efficient recruitment of enterance college, college advertisement, educational strength, industrial-educational cooperation, job oppertunities, financial support which are currently confronted with. Such efforts also can be alternative way to be a future direction as long-term plans of our college. In this report, we suggest plan for collective and long-term schemes against current college problems Moreover, even though a proposed plan as first step is to limit to Susung-Ku area, this system for practical application and harmony can be applied to other county areas without any additional investment and efforts in the future.

Pattern Search를 이용한 축구전용 경기장의 최적의 조명기구 위치 산정

權炳徽,崔棅淑,徐梵寬 홍익대학교 산업기술연구소 2003 産業技術 Vol.13 No.-

One essential contribution to a successful soccer game, which is still not always recognised as such, is the standard and quality of the lighting system. This is not only for TV transmissions, but also for the general practising of the sports. But, on too many occasions, sport activities and events have been allocated with insufficient or Inappropriate lighting system. inadequate lighting spoils not only the pleasure and the interests of active sportsmen, but also the comfort of the spectators in both the stadium and at home watching their TV. So this paper newly proposes the algorithm for searching of luminaire position which can be applied to the design stage.

Application of cluster analysis for the hydrogeochemical factors of saline groundwater in Kimje, Korea

김지훈,Byoung-Woo Yum,김락현,고동찬,Tae-Jin Cheong,Jeongho Lee 한국지질과학협의회 2003 Geosciences Journal Vol.7 No.4

Park, Y.S., Kim, J.K. and Kim, J., 201, Petrochemistry of Granitoids322 Ji-Hoon Kim, Byoung-Wo Yum, Rak-Hyeon Kim, Dong-Chan Koh, Tae-Jin Cheong, Jeongho Lee and Ho-Wan Changin the Youngwang-Kimje area, Korea. Economic and Environ-mental Geology, 34, 55-70 (in Korean with English abstract).Price, B.N. and Calvert, S.E., 1977, The contrasting geochemicalbehaviors of iodine and bromine in resent sediments from theNambian Shelf. Geochimica et Cosmochimica Acta, 41, 1769-1775.Richter, B.C., Kreitler, C.W. and Bledsoe, B.E., 1993, Geochemicaltechniques of identifying sources for groundwater salinization.CRC Pres, New York, 285 p.Stumm, W. and Morgan, J.J., 196, Aquatic chemistry: chemicalequilibria and rates in natural waters. 3rd edn. Wiley, New York,1022 p.

나노인덴테이션을 이용한 인체 피질골 골층판의 물성연구

노병욱,김병일,배성인,송정일 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

In the proposed research plan, the effects of anisotropic and time-dependent mechanical properties on nanoindentation measurements of osteonic lamellae in a human cortical bone are investigated. The most popular method(Oliver-Pharr method) in nanoindentation data analysis is based on the assumption of elastic isotropy. Since cortical bone has exhibited anisotropy, it is necessary to consider the effects of anisotropy on nanoindentation measurement for cortical bone. By comparison with the contact area obtained from monitoring the contact profile in FEA simulations, the Oliver-Pharr method was found to underpredict or overpredict the contact area due to effects of anisotropy. The mount of error depended on the indentation. The indentation modulus results and were also similar to moduli calculated from mathematical model. The Oliver-Pharr method has been shown to be useful for providing first order approximations in analysis of anisotropic mechanical properties of cortical bone, although the indentation modulus is influenced by anisotropy.