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New Controller Design Method Based on the Data Conversion Method
Ryota Arimura,Chinthaka Premachandra,Kiyotaka Kato 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
For targeting a feedback system with an unknown plant (controlled object), there are several methods for controller designing. In order to reduce costs, conventional methods use a single set of experimental I/O data to design a controller. In this paper, we propose a new method for this purpose, which improves the conventional data conversion method (DCM) and enables us to design a controller by giving an outline figure of the ideal output. In the proposed method, two kinds of the I/O data of the plant are defined. One data is obtained from the linearity of the plant, experimental data (single set of I/O), and an unknown vector. The other is obtained from the structure of a feedback system when the ideal output is given. A controller is designed by matching these two data. Because designing with giving the ideal output directly is possible, this method provides a design environment that makes it possible to reflect a user’s idea. Furthermore, proposed method produces a more appropriate parameter for the controller. We confirmed the effectiveness of new method by conducting simulation experiments. In the experiments, we compared proposed method with conventional DCM, and designed a controller by assuming the outline of the ideal output. The result of proposed method showed better performances compared to the conventional methods.
Mammalian Bax initiates plant cell death through organelle destruction
Yoshinaga, Keiko,Arimura, Shin-ich,Hirata, Aiko,Niwa, Yasuo,Yun, Dae-Jin,Tsutsumi, Nobuhiro,Uchimiya, Hirofumi,Yamada, Maki Kawai Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.
Mammalian Bax is known to cause cell death when expressed in plants. We examined transgenic plants expressing both Bax and oraganelle-targeted green fluorescent protein to determine the cellular changes that occur during Bax-induced cell death. The mitochondria changed morphologically from being bacilli-shaped to being round, eventually becoming swollen. Mitochondria streaming also stopped. The chloroplasts lost membrane function and their contents leaked out, followed by the disruption of the vacuole. Light was not essential for Bax-induced ion leakage or organelle disruption. These results indicate that Bax-induces temporal and spatial cell death events at the organelle level in the plant. A heterologous system, using Bax, would therefor be available to investigate cell death, which is commonly conserved in animals and plants
Design of Two Degree of Freedom Controller Using Data Conversion Method
Shota Higuchi,Ryota Arimura,Chinthaka Premachandra,Kiyotaka Kato 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10
Several data-driven design methods for a feedback controller for an unknown plant were studied. The data conversion method (DCM), which is one of the methods, has improved the design ability for more various plants by using a new approach. This paper applies the revised DCM to a two degree of freedom controller. First, the paper discusses a theory when applying DCM to a two degree of freedom controller. Then, it discusses the application of DCM to three structures of two degree of freedom controllers. Several experiments show that a controller can be directly designed from outline waveforms to a two degree of freedom controller. As a result, the paper shows that DCM is a convenient method for designing a two degree of freedom controller compared to conventional methods.
Liu, Tiejun,Miura, Shigenobu,Arimura, Tomohiro,Tei, Min-Yi,Park, Enoch Y.,Okabe, Mitsuyasu The Korean Society for Biotechnology and Bioengine 2005 Biotechnology and Bioprocess Engineering Vol.10 No.6
Various processes which produce L-lactic acid using ammonia-tolerant mutant strain, Rhizopus sp. MK-96-1196, in a 3L airlift bioreactor were evaluated. When the fed-batch culture was carried out by keeping the glucose concentration at 30g/L, more than 140 g/L of L-lactic acid was produced with a product yield of 83%. In the case of the batch culture with 200g/L of initial glucose concentration, 121g/L of L-lactic acid was obtained but the low product yield based on the amount of glucose consumed. In the case of a continuous culture, 1.5g/L/h of the volumetric productivity with a product yield of 71% was achieved at dilution rate of $0.024\;h^{-1}$. Basis on these results three processes were evaluated by simple variable cost estimation including carbon source, steam, and waste treatment costs. The total variable costs of the fed-batch and continuous cultures were 88% and 140%, respectively, compared to that of batch culture. The fed-batch culture with high L-lactic acid concentration and high product yield decreased variable costs, and was the best-suited for the industrial production of L-lactic acid.
Mitsuyasu Okabe,Tiejun Liu,Shigenobu Miura,Tomohiro Arimura,Min-Yi Tei,Enoch Y. Park 한국생물공학회 2005 Biotechnology and Bioprocess Engineering Vol.10 No.6
Various processes which produce L-lactic acid using ammonia-tolerant mutant strain, Rhizopus sp. MK-96-1196, in a 3 L airlift bioreactor were evaluated. When the fed-batch culture was carried out by keeping the glucose concentration at 30 g/L, more than 140 g/L of L-lactic acid was produced with a product yield of 83%. In the case of the batch culture with 200 g/L of initial glucose concentration, 121 g/L of L-lactic acid was obtained but the low product yield based on the amount of glucose consumed. In the case of a continuous culture, 1.5 g/L/h of the volumetric productivity with a product yield of 71% was achieved at dilution rate of 0.024 h-1. Basis on these results three processes were evaluated by simple variable cost estimation including carbon source, steam, and waste treatment costs. The total variable costs of the fed-batch and continuous cultures were 88% and 140%, respectively, compared to that of batch culture. The fed-batch culture with high L-lactic acid concentration and high product yield decreased variable costs, and was the best-suited for the industrial production of L-lactic acid.
Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer
Kentaro Yamashita,Ryo Suzuki,Toshiyuki Kubo,Kei Onodera,Tomoya Iida,Mayuko Saito,Yoshiaki Arimura,Takao Endo,Masanori Nojima,Hiroshi Nakase 거트앤리버 소화기연관학회협의회 2019 Gut and Liver Vol.13 No.4
Background/Aims: Fundic gland polyps (FGPs), hyperplastic polyps (HPs), and xanthomas (XTs) are common benign gastric lesions that can be diagnosed by endoscopic appearance alone in most cases. The aim of this study was to evaluate associations between gastric cancer and these benign lesions. Methods: Two expert endoscopists reviewed a series of gastroscopy images. FGPs, HPs, and XTs were diagnosed by endoscopic appearance, whereas all gastric cancers were confirmed pathologically. Results: Of the 1,227 patients reviewed, 114 (9.3%) had a concurrent or past history of gastric cancer. The overall prevalences of FGPs, HPs and XTs were 9.4%, 6.3% and 14.2%, respectively. HPs and XTs coexisted in 1.6% of patients, whereas other combinations were rarer. XTs were observed in 39.3% and 11.5% of patients with and without gastric cancer, respectively (p<0.001). In contrast, no gastric cancer patients had FGPs, whereas 10.4% of patients without cancer had FGPs (p<0.001). The prevalence of HPs was similar between the two groups (8.8% and 6.0% of patients with and without cancer, respectively, p=0.29). Multivariate and Mantel-Haenszel analyses demonstrated that XTs were positively associated and FGPs were negatively associated with gastric cancer. Conclusions: XTs and FGPs might be useful as endoscopic risk indicators for monitoring gastric cancer.