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전승현(Seung Hyeon Jeon),정민주(Min Ju Jung),정강현(Kang Hyun Chung),윤진아(Jin-A Yoon),안정희(Jeung Hee An) 한국식품영양과학회 2019 한국식품영양과학회지 Vol.48 No.6
본 연구에서는 다양한 생리활성 기능과 항산화력을 가진 미강을 0, 5, 10, 15%로 함유하는 절편을 제조한 후 수분 함량, pH, 색도, 아밀로스 함량, texture 측정, 항산화 활성, 항염증 활성을 측정하였다. 미강 절편의 수분 함량과 pH는 미강의 농도가 증가할수록 감소하였다. 색도 측정 결과 명도는 0%가 79.32, 15%일 때 54.48로 미강 함량이 증가할수록 값이 감소하였지만, 적색도와 황색도는 미강 함량이 증가함에 따라 높아지는 경향을 보였다. 아밀로스 함량은 15% 첨가군에서 13.54%로 가장 낮았다. Texture 측정 결과 경도와 부착성은 미강 함량이 증가할수록 값이 높아지는 경향을 보였고, 응집성은 감소하였다(P<0.05). 총 폴리페놀 함량은 15% 미강 절편의 에탄올 추출물에서 653.14 ㎍ GAE/100 ㎎, 물 추출물에서는 604.93 ㎍ GAE/100 ㎎으로 가장 높았으며, 총 플라보노이드와 탄닌 함량 또한 미강 함량에 비례하여 높은 활성을 보였다. DPPH 라디칼 소거능, ABTS 라디칼 소거능, 환원력도 미강 농도에 의존하여 유의적으로 증가하는 결과를 나타내었다(P<0.05). LPS로 NO 생성을 유도한 대식세포에 추출물을 250 ㎍/mL로 처리하여 NO 생성능을 비교한 결과, LPS 처리군에 비해 미강 함량에 의존하여 유의적으로 감소하는 것을 확인하였다(P<0.05). 본 연구 결과 미강은 항산화, 항염증 식품으로써의 가능성을 확인하였으며, 가격이 저렴하고 쌀보다 생리활성이 뛰어나 쌀의 일부분을 대체할 수 있어 경제적으로도 큰 이점을 지닐 수 있을 것이라 생각된다. This study investigated the quality characteristics and biological activities of Jeolpyeon added with rice bran. Jeolpyeon was prepared by the addition of rice flour and 0% (control), 5%, 10%, and 15% rice bran. The moisture content and pH decreased with increasing concentration of rice bran. The lightness of the sample was reduced significantly, but the redness and yellowness level increased with increasing rice bran content (P<0.05). Jeolpyeon added with 15% rice bran showed the lowest amylose contents (13.54%). The hardness and adhesiveness of texture increased with increasing rice bran content while the cohesiveness was decreased. The polyphenol contents of the ethanol and water extract of Jeolpyeon added with 15% rice bran were 653.14 ㎍ gallic acid equivalent (GAE)/100 ㎎ and 604.93 ㎍ GAE/100 ㎎, respectively. The flavonoid and tannic acid contents increased with increasing rice bran concentration. The 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 1,1-diphenyl-2-picrylhydrazyl radical scavenging ability and reducing power activities increased significantly with increasing rice bran concentration (P<0.05). In addition, Jeolpyeon added with rice bran inhibited the formation of nitric oxide induced by lipopolysaccharide in RAW 264.7 cells (P<0.05). These results suggest that rice bran can be used effectively as a functional food with anti-free radical scavenging and anti-inflammatory activities.
고지방식으로 생육한 생쥐 간에서 백삼과 홍삼 추출물의 항산화 효과
전보현(Bo Hyun Jeon),성금수(Geum Su Seong),전승기(Seung Gi Chun),성종환(Jong Hwan Sung),장재철(Che Chul Chang) 고려인삼학회 2005 Journal of Ginseng Research Vol.29 No.3
This study was to examine antioxidative effects of ginseng extracts on liver of high fat diet-treated mice. ICR male mice were given high fat diet with red ginseng or white ginseng extracts (500, 1500, 3000 ㎎/㎏/day, orally) for 4 weeks. We also investigated the relationship between lipid peroxidation and ginseng extracts on the oxidative stress. We measured the levels of malondialdehyde (MDA, a marker of lipid peroxidation), hydrogen peroxide, superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione (GSH) in liver tissue. The activities of SOD was generally low in all ginseng extract groups. But the activity of GPx was high in all ginseng extract groups. The hydrogen peroxide contents were similar in almost all groups. The level of GSH was higher in all ginseng extract group in high fat diet (FD) group. The levels of MDA (the end product of lipid peroxidation) were lower in all ginseng extract groups than in FD group. These results that the antioxidant effects of red ginseng and white ginseng extracts prevent oxidative damage by antioxidant effects involving SOD, GPx and increasing the ability of the body to synthesize endogenous antioxidants. It was concluded that ginseng can protect against oxidative stress by high fat diet through its antioxidant properties.
점액성 세관 방추세포 신장암종의 압착도말 세포소견 - 1예 보고 -
원규연,김교영,임성직,김현철,전승현,Won, Kyu-Yeoun,Kim, Gou-Young,Lim, Sung-Jig,Kim, Hyun-Cheol,Jeon, Seung-Hyun The Korean Society for Cytopathology 2008 대한세포병리학회지 Vol.19 No.2
The recent WHO classification has recognized mucinous tubular and spindle cell carcinoma (MTSCC) as a distinct entity of renal cell carcinoma, exhibiting a mixed pattern of tubules and a surrounding spindle cell proliferation within a myxoid stroma, with low-grade nuclear features. A 51-year-old woman had an incidentally discovered renal mass. Radiologic examination revealed a large, well defined mass in the lower pole of the right kidney; a right radical nephrectomy was performed. Imprint cytologic smears from fresh surgical specimens showed cellular, cohesive clusters with thick, broad trabecular arrangements and branching structures. On high power fields, the tumor was composed of round-to-oval low-grade nuclei with vesicular chromatin and small nucleoli. The tumor cells had indistinct borders and pale, eosinophilic cytoplasm, In some areas, round-to-elongated tubular structures and spindle cell patterns were noted. Chronic inflammatory cell infiltration was noted, along with a mucinous back-ground and occasional psammoma bodies. Neither significant cytologic atypia nor mitosis was seen.
컴퓨터활용교육 : ALTERA Development and Education Board를 이용한 문제중심학습(PBL) 기반 디지털 논리회로 교수-학습전략 제안
윤일규 ( Il Kyu Yoon ),강세현 ( Se Hyun Kang ),김사무엘 ( Samuel Kim ),전승원 ( Seung Won Jeon ),주현준 ( Hyun Jun Ju ),홍광표 ( Gwang Pyo Hong ),서태원 ( Tae Won Seo ) 한국컴퓨터교육학회 2011 한국컴퓨터교육학회 학술발표대회논문집 Vol.15 No.1
디지털 논리회로는 정보 교육 분야에서 핵심적인 교과목 중 하나로써 그 중요성이 강조되고 있다. 이에 따라 디지털 논리회로 학습에 관련된 다양한 연구가 진행되었으며 그 효과 성이 검증되었다. 그러나 대부분의 디지털 논리회로에 대한 연구가 학습에 활용될 수 있는 콘텐츠 개발이나 시뮬레이터 개발에 집중되어 왔다. 따라서 본 연구에서는 ALTERA Development and Education Board를 활용하여 문제중심학습(PBL)기반 디지털 논리회로 교수-학습전략을 제안하였다. 본 연구에서 제안된 PBL 기반의 디지털 논리회로 교수-학습 전략은 학습자들의 흥미와 학습 동기를 향상 시킬 수 있을 것으로 기대된다.
민경은(Gyeong Eun Min),전승현(Seung Hyun Jeon) 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.1
Transurethral resection of bladder tumor (TURB) is a standard method for treatment and diagnosis of non-muscle invasive bladder tumor. However, early recurrence rates after TURB is relatively high, 15% in a single tumor, and up to 45% in multiple tumors, which do not seem to be acceptable. These high recurrence rates may be caused by incomplete tumor resection, aggressive tumor biology, or implantation of tumor cells shed during surgery. Herein, we investigated the ways to improve the outcomes of TURB.