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뉴트로 디자인과 레트로 디자인이 소비자 구매의도에 미치는 영향 : 저관여 제품 패키지 디자인을 중심으로
안현영(An, Hyun Young),이창근(Lee, Chang Keun) 한국디자인리서치학회 2021 한국디자인리서치 Vol.6 No.1
21세기는 소비자의 오감을 자극하고 만족시켜야 가치가 창조되는 체험 경제의 감성소비시대에 살고 있다. 고도의 삶의 질을 추구하고 뚜렷한 감정표현과 적극적인 소비성향은 뉴트로 트랜드 현상으로 현대사회시장에 글로벌화 되어 나타났다. 과거를 경험한 직접소비자와 경험을 해보지 못했던 간접소비자와의 연합적 문화교류현상이다. 과거회귀의 재현은 세대 간의 공감대를 형성하고 문화이역을 줄여 소통의 연결고리가 되고 있다. 오래된 디자인을 소환하는 것은 외적으로는 지나간 시대·세계에 대한 향수문화현상이다. 이것을 복고풍이라고 불리며 현대인의 소비성장에 다양한 분야로 확산되어 메가트랜드로 자리 잡고 있다. 본 연구는 이런 현상에 대한 노스탤지어-레트로-뉴트로의 개념을 정의하고 소비자 구매행동으로 이끌어주는 구매의도 특성을 이해하고 설문을 진행하였다. 본 연구의 결과에서 뉴트로 디자인과 레트로 디자인이 소비자 구매의도에 주목성과 호기심, 친근함의 속성이 가장 많은 영향을 나타내었다. 이러한 결과에 대한 모형 틀을 디자인프로세스에 적용함으로 질적양적 세대별 모든 소비자의 니즈에 충족시키는 디자인 문화장르로 계속 발전 될 것으로 사료된다. The 21st century is living in an era of emotional consumption in an experience economy where value is created only when it stimulates and satisfies consumers five senses of consumers. The pursuit of high quality of life, clear expression of emotions and active consumption propensity have been globalized in the modern social market due to the Newtro trend phenomenon. This is a phenomenon of cultural exchange between direct consumers who have experienced the past and indirect consumers who have never experienced it. Reproduction of the past regression is becoming a link to communication by forming a consensus among generations and reducing cultural translation. Summoning old designs is outwardly a nostalgic cultural phenomenon about the past and the world. This is called retro style, and it has spread to various fields in modern consumption growth and has become a big trend. This work defines the concept of a Nostalgir-Retro-Newtro for this phenomenon and conducts a survey understanding and understanding the nature of the intention of purchasing that leads to consumer purchasing behavior. In the results of this study, the nature of attention, curiosity, and familiarity with consumer purchasing intentions was most influenced by Newtro design and Retro design. By applying the model framework for these results to the design process, it is believed that it will continue to develop into a design culture genre that meets the needs of all consumers of each qualitative and quantitative generation.
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Warfarin에 의한 과도한 항응고 효과의 치료현황 평가
전혜영,신가영,김은영,안현영,장효인,손기호 한국병원약사회 2009 병원약사회지 Vol.26 No.1
Abstract: Warfarin is one of the most effective agents for prevention and treatment of venous and arterial thrombosis but may cause bleeding, especially if overdosed. To minimize the risk of bleeding, close monitoring of prothrombin time(PT)-generally expressed as the international normalized ratio(INR)-is required with warfarin administration. Despite close monitoring and dose adjustment, numerous factors can cause increasing INR and subsequent bleeding complica tions. The American College of Chest Physicians(ACCP) has suggested the guidelines-of the man-agement of excessive warfarin anticoagulation. But the guidelines-have not been established in Korea and there is little data on the clinical problems and treatments of over-anticoagulation. This study evaluated the status of and causes of excessive warfarin anticoagulation as well as adherence to the ACCP guidelines-for treatment of excessive anticoagulation at the Samsung Medical Center(SMC). Patients who were on warfarin therapy and presented with an INR of )3.5 from March 1 to August 31, 2008, were included and observed retrospectively by reviewing med-ical records. Adherence to the 2004 ACCP guidelines-was also assessed. A total of 406 episodes in 347 patients were analyzed. At enrollment, 365 patients(89.9%) had an INR<9.0 and no significant bleeding; 41 patients(10.1%) had an INR)9.0 or serious bleeding. Common causes of elevated INR were drug-interaction(21.4%), followed by concurrent acute disease(13.8%). 322 patients (79.3%) were treated appropriately according to the ACCP guidelines-. Among nonadherents(19.2%), 9.4% were overtreated, 8.4% were undertreated and 1.5% were treated with vitamin K₁through inap-propriate routes. Lack of adherence was primarily attributed to excessive use of fresh frozen plasma(FFP) and vitamin K₁and tendency to overlook treatment in the lower INR range. In this study, adherence to the ACCP guidelines-was higher than that in other previous studies and the administration routes of vitamin K₁were improved. But we found inappropriate uses of FFP and vitamin K₁. The results of this study provide important clues for the development of guidelines-that would be available for Korean patients to prevent and manage warfarin-induced coagulopa-thy.
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콜라겐에 의한 난소암 세포주의 Matrix-metalloproteinases (MMPs) 의 발현
김재동,김동주,김재선,배석년,남궁성은,강미지,안현영 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.11
Objective : Metastatic dissemination of epithelial ovarian carcinoma is thought to be mediated via tumor cell exfoliation into the peritoneal cavity, followed adhesion to and invasion through the mesothelium which overlies the contents of the peritoneal cavity. MMP-2 is secreted as a zymogen, the activation of which has been associated with metastatic progression in human ovarian cancer cell lines. Methods : We have utilized short-term cultures to analyze the effect of specific extracellular matrix proteins, type I collagen. Results : Culturing Caov-4 ovarian cell line on type I collagen led to a significant increase in conversion of the MMP-2,72kD to the MMP-2,66kD, and MT-MMP expression. MT-MMP expression correlates with expression and activation of MMP-2 during malignant progression. Altered MT-MMP expression in ovarian cell lines might contribute to MMP-2 activation, which facilitates invasion of these tumors. Conclusion : In summary, we found increased expression of MT-MMP that correlated with increased level of activated MMP-2 and cellular counts in chemoinvasion assay in Caov-3 cell line. But no significant increases in Skov-4 cell line on type I collagen. Conclusion: These data suggest that type I collagen induces MMP-2 activation in part by up-regulation of MT-MMP expression but has a more complicated mode of action involving additional processes.
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