국산 Lidocaine 알칼리화를 위한 Bicarbonate 혼합시 침전유발 최소량에 대한 고찰

이선호,김현수,곽인숙,안원식,최관호,김광민,손민제 대한마취과학회 2000 Korean Journal of Anesthesiology Vol.39 No.5

Background : When local anesthetics for regional anesthesia is used, usually small amounts of bicar-bonate are added for rapid onset. This addition gives the mixed solution a more alkaline pH. The following result is an increased unionized form of the local anesthetic and rapid penetration of the drug into tiissue. Unfortunately, no data about adequate mixing volumes of domestic lidocaine and bicarbonate is available. Methods : We examined six mixing pairs of two kinds of 2% lidocaines and three kinds of 8.4% bicarbonates for minimum volumes of bicarbonate to cause a precipitation of 2% 20 ml lidocaine. Results : The mean volumes of bicarbonate to cause precipitation were 1.54 ml for Kwang-Myung lidocaine with Kwang-Myung bicarbonate, 2.90 ml for Kwang-Myung lidocaine with Dae-Won bicarbonate, 2.73 ml for Kwang-Myung lidocaine with Je-Il bicarbonate, 0.97 ml for Je-Il lidocaine with Kwang-Myung bicarbonate, 1.26ml for Je-Il lidocaine with Dae-Won bicarbonate and 1.39 ml for Je-Il lidocaine with Je-Il bicarbonate. Conclusions : We conclude that the Kwang-Myung lidocaine and the Je-Il lidocaine could cause precipitation when mixing with a smaller bicarbonate volume than foreign textbook recommended. (Korean J Anesthesiol 2000; 39: 726-729)

食用 갓(Brassica juncea Coss.)의 人工交配 및 葉色의 遺傳

安奬淳,金光秀 全南大學校 農漁村開發硏究所 1980 農業科學技術硏究 Vol.15 No.-

本 硏究는 菜蔬로써의 價値는 높으나 硏究가 거의 되어 있지 않는 食用 갓의 人工交配와 葉色의 遺傳에 關한 品種育成을 爲한 基礎調査이다. 갓에는 綠色, 談紫色(表面 紫色), 濃紫色(兩面紫色)이 있고 그 중 濃紫色의 것이 商品價値가 가장 크다. 갓의 人工交配에서의 平均 結實率은 73% 程度이었고, 갓에는 自家 및 他家不和合性은 認定되지 않았다. 人工交配는 開花 1日前, 2日前, 3日前의 花蓄 모두 實用上 使用이 可能하고 花粉만 求得되면 日中 어느 時核에나 實施할수 있는 것으로 나타났다. 갓의 葉色은 濃紫色이 優性인 單因子에 依한 形質이고 幼苗의 紫色子葉은 濃紫色의 遺傳標識으로 使用될 수 있는 것으로 나타났다. The artificial pollinations and inheritance of leaf color in leaf mustard is reported for the first time. Leaf mustard is a minor vegetable crop in Korea but has long been grown as a valuable salad and spice crop in Chonnam Province. Three types of it are distinguished on the basis of leaf color; green, light purple and dark purple. The dark purple type is the most accepted one in markets. Overall fruit set from artificial pollination averaged 73% and self or cross-incompatibility was not noticed. Flower buds on one, two and three days before flowering were found to be practically equally good for artificial pollination. The fruit sets from artificial pollinations did not very at any time of pollination during the day from 9 am. to 3 pm. The purple leaf color was found to be conditioned by a single dominate gene and purple cotyledons was genetic marker of dark purple leaves.

비완압형 어태치먼트의 위치에 따른 하악 가철성 국소위치의 지지조직에서의 저작압 분산 양태에 관한 3차원 유한요소적 연구

안원준,우순섭,이영수,심광섭,유광희 한양대학교 의과대학 1999 한양의대 학술지 Vol.19 No.1

The purpose of this study was to evaluate the stress patterns developed in supporting structures by removable partial denture with an extracoronal and an intracoronal rigid attachment. The mandibular removable partial dentures with Mini S-G (extracoronal) and C-M Box (intracoronal) attachment were constructed. Under 100N, 200N of vertical and 25N, 50N of lateral loads at the 1st and 2nd lower molar, stress distribution patterns and displacement were analyzed with three dimensional finite element method. The result were as follows: 1. There was no apparent difference in the patterns of stress distribution between rigid extracoronal and rigid intracironal attachments. 2. In case of the single abutment tooth with the rigid intracoronal attachment, it was not proper to preserve the abutment tooth. 3. With splinted abutments, the stress was distributed through all the root surface of both abutments. With single abutment, the stress was concentrated on the distal root surface of abutment. 4. With splinted abutments, there was not clear difference in the patterns of stress distribution with or without lingual bracing part. 5. In case of the single abutment tooth with the rigid intracoronal attachment and cantilever. More stress was concentrated around the abutment tooth with the lingual bracing part under loaded concentrated force and the abutment tooth without the lingual bracing part under loaded distributed force. 6. In case of the splinted abutments with the rigid extracoronal and intracoronal attachment, the denture base was displaced posteriorly and inferiorly when the force was applied. 7. In case of the single abutment tooth with the rigid intracoronal attachment, there was little displacement at the denture base.

Hydrotalcite의 製造條件에 關한 硏究

안세민,신화우,최광식,이광표,장영수 원광대학교 식품약품안전성연구소 1993 食品藥品安全性硏究 Vol.6 No.-

Hydrotalcite is mainly used as a antacid and adsorbent. It is Well Known that the yield of hydrotalcite produced is greatly affected by the preparation conbition such as the reactant concetration, reaction temperature, reaction time, mole ratio of reactants and grying tepeeature, etc. the purpose of this study is to investigate the optimum preparation condition of hydrotalcite. Arandomived complete block design suggested by G.E.P.Box and K.B. Wilson was appliedfor this purpose. Hydrotalcite was prepared by reacting sodium carbonate. Magnesium oxide and Aluminum sulfate solutions in this study. The optimum preparation condition of hydrotalcite obtained from this study is as follows: 1) The reaction temperature range is 48-63℃ 2) The concentration of reactant solutions is about 20% 3) The optimum mole-ratio (MgO/Al. sulfate) is 7.35-8.1. 4) The reacting time tatge is 10-11 min.. 5) The drying temperature range is 78-82℃ The outcome of D.S.C. indicated a desolvation of hydrotalcite occured at about 98℃ The dehydration of the compound ceased at about 250℃, and the decarboxylation ceased at about 446℃ The physical and chemical properties of hydrotalcite as medicine were studied by use of chemical analysis, bulk volume test and acid consuming capacity measurements.

고강도 무다짐 콘크리트의 최적배합 및 수화온도 특성

안종문,임희재,이광수,강훈 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

This research investigates experimentally an effect on the quality performance and hydration properties of the high strength self compacting concrete(H-SCC). The purpose of this study is to determine the optimum mix proportion of the SCC having good flowability, viscosity and no-segregation. For this purpose, 37 mix designs are tested by design factors including water binder ratio, binder content per unit volume of concrete, and fine and coarse aggregate volume ration. As test results of this study, the optimum mix proportion for level of concrete compressive strengths is as following. 1) f_(ck)=50MPa water binder ratio 36% ; binder content per unit volume of concrete 450kgf/m³ and fine and coarse aggregate volume ration 52%, 2) f-(ck)=60MPa water binder ratio 31% ; binder content per unit volume of concrete 500kgf/m³ and fine and coarse aggregate volume ration 48%.

암호알고리즘을 이용한 의사난수생성기의 구현

안성수,임광철 東新大學校 2003 論文集 Vol.13 No.-

Random Number Generators (RNG) are an important building block for algorithms and protocols in cryptography. They are paramount in the construction of ancryption keys and other cryptographic algorithm parameters. In practice, statistical testing is employed to gather evidence that a generator indeed produces numbers that appear to be random. Few resources are readily available to researchers in academia and industry who wish to analyze their newly developed RNG. The algorithms employ a one-way function G(t,c), where t is 128 bits, c is b bits (128, 512) and G(t,c) is 128 bits. One way to construct G is Rijndael. The 128-bit messagedigest output of the Rijndael algorithm, when message M is input, which is denoted by Rijndael(M).

수소동위원소 운반용기 단열 해석

김광락,이민수,백승우,이성호,안도희,임성팔,정흥석 한국공업화학회 2003 응용화학 Vol.7 No.2

The immobilized hydrogen as a titanium hydride could be used in a stainless steel vessel for the long-term storage of hydrogen isotopes. The design analysis of a hydrogen isotope transport container with capacity of 0.5 MCi tritium was carried out to confirm the performance of the safely requirement. In order to verify that the radioactive transport container complies with the requirements for the B(U) type container stipulated in the MOST regulation of transport container, thermal analysis were made for normal condition and hypothetical accident conditions during transport. Thermal analysis with the Heating-7 code under conditions of 38℃ for 7 days and 800℃ for 30 minutes showed that the container complied with the requirement for B(U) type transport container.

타이타늄 수소화물의 수소동위원소 분석

김광락,백승우,이민수,이성호,안도희,임성팔,정홍석 한국공업화학회 2002 응용화학 Vol.6 No.2

In the hydrogen isotope facility and the fiel cycle of the fision reactor, an effective means for analyzing hydrogen isotopes and decay product(helium) of tritium is very importat from the viewpoint of system operation and control. Chromatographic separation of the hydrogen isotopes mixture from titanium hydride was carried out by gas chromatograph at-196℃ for quantitative analytical purpose.Neon and partially deactivated alumina were employed as the carrier gas and the fixed column, respectively. The chromatogram with complete separation was observed in order ofH_2, HD and D_2 by the thermal conductivity detector. In addition, fairly good separation conditions were obtained in a shorter retention time without any appearance of nuclear spin isomers for the practical applications of the hydrogen isotope separation and analysis.

난소절제후 Estrogen을 투여한 흰쥐 대동맥에서 Protein Kinase C-α와 Fas 발현의 변화

이왕수,이상엽,안지현,송영빈,김학진,이광재,유재격,김상욱,김태호,김치정,류왕성 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3

Estrogen is believed to decrease coronary artery disease. Protein kinase C-α(PKCα)appear to be important in signal conduction pathways. Estrogen treatment increases catalytic activity of PKCα,and activation of PKCαcan modulate estrogen receptor levels and responsiveness. And it was reported that activation of PKC can protect cells from apoptosis induced by Fas ligation. But the beneficial effect of estrogen on PKCαwas not clearly demonstrated. The objective of this study was to evaluate the role of PKCαafter ovariectomy and estrogen therapy in rat aorta. The results were summarized as below: 1. The significant pathological changes were not observed in the rat aorta irrelevant to ovariectomy and estrogen therapy. 2. The expression of Fas was decreased in the aorta of estrogen-treated rats than that of ovariectomized rats without estrogen therapy. 3. Increased expression of PKCαwas more marked in the aprta of estrogen-treated rats than that of ovariectomized rat without estrogen therapy. In conclusion,PKCαmay be important in signal conduation pathway on the effect of estrogen. Activation of PKCαby estrogen reduced Fas expression, suggesting that PKCαactivation may play a role in protection against atherasclerosis. Further studies are needed to elucidate the role of PKCαafter estrogen therapy.

상대농도와 질량농도 측정법에 의한 기중 분진농도의 비교

정광호,성수원,안규동 가톨릭대학산업의학센타 산업의학연구소 1983 韓國의 産業醫學 Vol.22 No.1

This experiment was carried out to investigate the correlation of accuracy among five kinds of instruments which determined an airborne dust at the various locations of same type work. The results obtained were as follows; 1. Digital dust indicator-P type (DDI-P) instrument for determination of relative concentration was found not having significant variations when it was used without corrective coefficient to the quantitative concentration at the places with a few airborne dust in office and laboratory room. 2. Generally, there were the high correlations between determination values resulted by Digital dust indicator(DDI) and Piezobalance(PB). However, the correlation of two instruments to a filter weighing method was insignificant in the same type work. After determining several times (at least 5 times and over), it was desirable to fix the corrective-coefficient. 3. When the size of the particles of airborne dust was large or its concentration was high in suspended airborne dust, the determination values of High volume air sampler-Respirable(HVS(R)) were 2-4 times higher than that of Low volume air sampler-Respirable(LVS(R)). 4. The emyloyment of corrective coefficient for determination values of DDI and PB was not appropriate to HVS(R) comparing with LVS(R) because of the significant changeable differences. In addition, the determination instruments for relative concentration was not appropriate to using by itself at a manufactruing process. There were also problems about sampling time and evaluation when it was determined the total airborne dust with the open face type holder.