수증기 활성화법으로 제조된 영월 석탄계 활성탄의 특성 연구

이송우,권태훈,나영수,최동훈,류동춘,송승구 한국환경과학회 2000 한국환경과학회지 Vol.9 No.4

Activated carbons were prepared from Youngwall coal by steam activation in this study. The feasibility of the Youngwall coal to commercial activated carbon was examined. The variation of pore structures and the development of porosity in activated carbons were investigated by changing activation conditions in batch type apparatus. The values of BET surface area and adsorption capacity of iodine and methylene blue of the resulting activated carbons were obtained as high as 1,000㎡/g, 900㎎/g, 150㎖/g, respectively. Youngwall activated carbon prepared in this study showed much higher pore volume in pore diameter over l0Å than that of commercial reference activated carbon(Ningxia Taihua ZJ-15C) produced from China anthracite.

난지도 매립지에서 침출수 거동에 관한 연구

조원철,강동희,구태훈 중앙대학교 기술과학연구소 2000 기술과학연구소 논문집 Vol.30 No.-

최근 난지도 매립지는 침출수로 인한 지하수오염이 심각한 매립지 중 하나로 부각되고 있다. 본 연구는 난지도 매립지에서의 침출수 거동을 3차원 지하수 흐름을 모사 할 수 있는 MODFLOW(A Modular 3-D Finite Different Groundwater Flow Model)을 이용하여 분석하였고, 난지도 매립지에서의 침출수 발생량은 HELP(Hydraulic Evaluation of Landfill Performance)모델을 이용하여 추정하였다. 침출수 발생량은 최근 10년간의 기상 자료를 이용하여 산정 하였으며, 침출수 거동은 복토 전/후와 차수벽과 well 설치후의 시간 경과에 따른 침출수위의 변화를 계산하여 예측하였다. 본 연구는 난지도 매립지의 적절한 침출수 발생량과 침출수 거동을 예측하는데 있어 유용하게 사용될 것으로 사료된다. The Nanji landfill has recently became one of the most important site for groundwater contamination leachate transport. This study is to analyze the leachate transport in Nanji waste landfill using MODFLOW(A Modular 3-D Finite Different Groundwater Flow Model) model which can model three dimension groundwater flow. Leachate production rates are estimated by HELP(Hydraulic Evaluation of Landfill Performance) model and used weather records for recently 10 years. Leachate transport is predicted by a change of leachate level to after/before established HDPE, established slurry wall and wells. The purpose of this study is to predict appropriate leachate rates and leachate transport at Nanji waste landfill.

톨루엔의 一回 및 反復吸入 露出이 白鼠에 미치는 影響 : 血中 濃度 및 細胞外性 아미노酸 神經傳達物質의 濃度變化 Blood concentration and extracellular amino acid neurotransmitter levels

백승경,신윤열,박용훈,이진훈,최태혁,이완구 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

Development of a Knowledge Discovery System using Hierarchical Self-Organizing Map and Fuzzy Rule Generation

Tae Hoon Koo,Jong Tae Rhee 한국지능정보시스템학회 2001 한국지능정보시스템학회 기타 간행물 Vol.- No.-

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: Evidence for extrahepatic metabolism

Koo, Tae-Sung,Kim, Dae-Hyun,Ahn, Sung-Hoon,Kim, Kang-Pil,Kim, In-Wha,Seo, Seung-Yong,Suh, Young-Ger,Kim, Dae-Duk,Shim, Chang-Koo,Chung, Suk-Jae Wiley Subscription Services, Inc., A Wiley Company 2005 journal of pharmaceutical sciences Vol.94 No.10

<P>The objective of this study was to characterize the extent of the formation of the active (trans-alcohol form) and inactive (cis-alcohol) metabolites of loxoprofen and to compare the kinetics after its intragastric, intravenous, and intramuscular administrations in rats. After intravenous administration of the drug at doses of 5–20 mg/kg, the clearance and the volume of distribution for loxoprofen, and the ratios of the AUC for the metabolites to the parent drug were not statistically different with the dosage; the formation clearances were 1.08 and 0.87 mL/min/kg for the active and its isomeric metabolite, respectively. After the intragastric, intravenous, or intramuscular administration, AUC for loxoprofen and the metabolites at a dose of 10 mg/kg were not statistically different for the different routes of administration. The formation of the metabolites with the concomitant loss of loxoprofen was found in incubations with liver homogenates and blood but not with a muscle homogenate or plasma, indicating that the conversion of loxoprofen to the metabolites may occur both in the liver and extraheptic tissue(s). Thus, approximately 22% of the loxoprofen may have been converted to the active metabolite in the liver and the extraheptic tissue(s) and the pharmacokinetics of the active metabolite was independent of the route of administration. © 2005 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 94:2187-2197, 2005</P>

Definitive Radiotherapy versus Postoperative Radiotherapy for Tonsil Cancer

Tae Ryool Koo,우홍균,하정훈,성명훈,김광현,김범석,Tae Min Kim,Se-Hoon Lee,김동완,Dae-Seog Heo,Charn Il Park 대한암학회 2012 Cancer Research and Treatment Vol.44 No.4

Purpose The purpose of this study is to analyze treatment outcome of radiotherapy (RT) in patients with stage III-IV tonsil cancer managed by surgery followed by postoperative RT (SRT) and definitive chemoradiotherapy (CRT), and to thereby evaluate the most feasible treatment modality. Materials and Methods Of 124 patients, 67 underwent CRT, and 57 underwent SRT. We compared survival and complication rates in both groups. Results The median follow-up time was 57 months (range, 19 to 255 months) for surviving patients. At five years, locoregional progression-free survival (LRPFS) and overall survival (OS) were 88% and 80%, respectively. No significant difference in LRPFS (p=0.491) and OS (p=0.177)was observed between CRT and SRT. In multivariate analysis, old age and higher T stage showed a significant association with poor LRPFS, PFS, and OS; higher N stage showed an association with poor PFS and a trend of poor LRPFS, while no association with OS was observed; treatment modality (CRT and SRT) showed no association with LRFPS, PFS, and OS. Grade 3 or higher mucositis was observed in 12 patients (21%) in the SRT group, and 25patients (37%) in the CRT group. Conclusion Definitive CRT and SRT have similar treatment outcomes for patients with stage III-IV tonsil cancer. Although acute complication rate appears to be higher in the CRT group, it should be noted that not all data on complications were included in this retrospective study. To determine the most feasible treatment modality, not only mucositis and xerostomia, but also emotional aspect and quality of life, should be considered.

近世日本武士와 帶刀

Koo Tae Hoon(具兌勳) 일본사학회 1996 일본역사연구 Vol.4 No.-

Bushi in the Tokugawa period always wore two swords on the waist. Length and weight of the sword was made suitable for the carrier’s body condition. Sword decoration was also various according to personal taste. Therefore, everyone could know to whom the sword belonged by only its appearance. That is, the characters and values of the owner were reflected on the sword. Ruth Benedict once argued that Japanese had the tendency of considering his body and his sword as one. Bushi in the Tokugawa period though his sword was the same with the owner’s personality. Bushi tired not to forget the spirit of struggle and the spirit not to be afraid of dying over swords. Swords were the last only means that Bushi depended on when they were ready to die. Swords in Tokugawa ages were the symbol of Bushi. Bushi monopolized the night to carry sword. It was accomplished by the result of Sword Confiscation Policy in the Toyotomi period. The Toyotomi government planned the society that Bushi would monopolize swords to symbolize weapons and farmers should own only farming tools and devote themselves to production. Farmers accepted this logic without resistance. To wear two swords was Bushi privilege and also duty. When a Bushi went out without swords, he was punished. When he lost his swords, he was ridiculed. When his sword, furthermore, was taken away, his honor was difficult to recover. Especially, when he was robbed of his sword by a mean person and escaped away, he never wore his swords again. Namely, the status of Bushi was deprived. In the area governed by a certain Daimyo, the punishment to deprive a Bushi of his sword was often considered as heavier than death penalty. That a Bushi was deprived of his swords was as serious problem that his own existence was denied. Sword for the Japanese Bushi were not only weapon but also something to support his spirit.

Economic Statistical Design of Variable Sampling Interval □ Control Chart Based on Surrogate Variable using Genetic Algorithms

( Tae-hoon Lee ),( Sung-hoon Hong ),( Hyuck-moo Kwon ),( Min-koo Lee ) 한국품질경영학회 2015 한국품질경영학회 학술대회 Vol.2015 No.2

Purpose: In many cases, a □ control chart based on the performance variable is used in industrial fields. Typically, the control chart monitors the measurements of a performance variable itself. However, if the performance variable is too costly or impossible to measure, and a less expensive surrogate variable is available, the process may be more efficiently controlled using surrogate variables. In this paper, we present a model for the economic statistical design of a VSI (Variable Sampling Interval) □ control chart using a surrogate variable that is linearly correlated with the performance variable. Methodology/Approach: We derive the total average profit model from an economic viewpoint and apply the model to a Very High Temperature Reactor (VHTR) nuclear fuel measurement system and derive optimal result using genetic algorithms. Findings: Compared with the control chart based on the performance variable, the proposed model gives a larger expected net income per unit of time in the long-run if the correlation between the performance variable and the surrogate variable is relatively high. Research Limitation/implication: The proposed model was confined to the sample mean control chart under the assumption that a single assignable cause occurs according to the Poisson process. However, the model may also be extended to other types of control charts using a single or multiple assignable cause assumption such as VSS (Variable Sample Size) □ control chart, EWMA, CUSUM charts and so on. Originality/Value of paper: We develop a new economic statistical design for the VSI □-control chart using a surrogate variable under the situation that a performance variable is expensive, timeconsuming, or even destructive.

Definitive Radiotherapy versus Postoperative Radiotherapy for Tonsil Cancer

Koo, Tae Ryool,Wu, Hong-Gyun,Hah, J. Hun,Sung, Myung-Whun,Kim, Kwang-Hyun,Keam, Bhumsuk,Kim, Tae Min,Lee, Se-Hoon,Kim, Dong-Wan,Heo, Dae-Seog,Park, Charn Il Korean Cancer Association 2012 Cancer Research and Treatment Vol.44 No.4

<P><B>Purpose</B></P><P>The purpose of this study is to analyze treatment outcome of radiotherapy (RT) in patients with stage III-IV tonsil cancer managed by surgery followed by postoperative RT (SRT) and definitive chemoradiotherapy (CRT), and to thereby evaluate the most feasible treatment modality.</P><P><B>Materials and Methods</B></P><P>Of 124 patients, 67 underwent CRT, and 57 underwent SRT. We compared survival and complication rates in both groups.</P><P><B>Results</B></P><P>The median follow-up time was 57 months (range, 19 to 255 months) for surviving patients. At five years, locoregional progression-free survival (LRPFS) and overall survival (OS) were 88% and 80%, respectively. No significant difference in LRPFS (p=0.491) and OS (p=0.177) was observed between CRT and SRT. In multivariate analysis, old age and higher T stage showed a significant association with poor LRPFS, PFS, and OS; higher N stage showed an association with poor PFS and a trend of poor LRPFS, while no association with OS was observed; treatment modality (CRT and SRT) showed no association with LRFPS, PFS, and OS. Grade 3 or higher mucositis was observed in 12 patients (21%) in the SRT group, and 25 patients (37%) in the CRT group.</P><P><B>Conclusion</B></P><P>Definitive CRT and SRT have similar treatment outcomes for patients with stage III-IV tonsil cancer. Although acute complication rate appears to be higher in the CRT group, it should be noted that not all data on complications were included in this retrospective study. To determine the most feasible treatment modality, not only mucositis and xerostomia, but also emotional aspect and quality of life, should be considered.</P>

Changes in the Aggressiveness and Fecundity of Hot Pepper Anthracnose Pathogen (Colletotricum acutatum) under Elevated CO₂ and Temperature over 100 Infection Cycles

Koo, Tae-Hoon,Hong, Sung-Jun,Yun, Sung-Chul The Korean Society of Plant Pathology 2016 Plant Pathology Journal Vol.32 No.3

We observed the changes in aggressiveness and fecundity of the anthracnose pathogen Colletotrichum acutatum on hot pepper, under the ambient and the twice-ambient treatments. Artificial infection was repeated over 100 cycles for ambient ($25^{\circ}C/400ppm$ $CO_2$) and twice-ambient ($30^{\circ}C/700ppm$ $CO_2$) growth chamber conditions, over 3 years. During repeated infection cycles (ICs) on green-pepper fruits, the aggressiveness (incidence [% of diseased fruits among 20 inoculated fruits] and severity [lesion length in mm] of infection) and fecundity (the average number of spores per five lesions) of the pathogen were measured in each cycle and compared between the ambient and twice-ambient treatments, and also between the early (ICs 31-50) and late (ICs 81-100) generations. In summary, the pathogen's aggressiveness and fecundity were significantly lower in the late generation. It is likely that aggressiveness and fecundity of C. acutatum may be reduced as global $CO_2$ and temperatures increase.