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정지용,윤나라,강대웅,오종찬,장재현,선길홍,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1
Aplastic anemia is a disease characterized by pancytopenia in the peripheral blood and hypocellular bone marrow with the fatty infiltration. The causes of the acquired aplastic anemia were usually related to drugs and immune-related diseases. A 34-years old man was admitted due to general weakness. He has been going hemodialysis for 2 years because of end stage renal disease (ESRD) due to chronic glomerulonephritis. At admission, laboratory tests showed hemoglobin 6.2 g/dL, hematocrit 18.0 %, WBC 5,710mm (neutrophil 71.8%, lymphocyte 19.1%, monocyte 5.9%), reticulocyte 1.9%, platelet 93,000/mm, Fe 12.8 ug/dL, TIBC 204 ug/dL, ferritin 941.47 ng /ml, haptoglobin 0.72 g/L, vitamin B12 508.17 pmol/L, folate 24 ng/mL, total protein 6.54 g/dL, albumin 3.76 g/dL, Alk. pohsphatase 79 IU/L, AST 30.0 IU/L, ALT 39.7 IU/L, total bilirubin 0.57 mg/dl, BUN 79.4 mg/dl and creatinine 10.18 mg/dl. Peripheral blood smear showed the normocytic normochromic anemia with anisocytosis. Anemia was diagnosed but it was irresponsive to the recombinant human erythropoietin (EPO) and blood transfusion. In the bone marrow aspiration smear were there the hypoplastic myeloid and erythroid precursors. The bone marrow biopsy section showed the hypoplasia of all components (10-20%) and the fatty infiltration. We have experienced one case of the idiopathic aplastic anemia in a patient going through hemodialysis and we just report it with documentary records. 저자들은 혈액 투석 중인 환자에서 약물, 면역계 이상등의 원인을 발견할 수 없었음에도 재생 불량성 빈혈이 발생한 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.
강대웅,정지용,윤나라,안치용,김종오,신병철,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2
Background: Some cases of QT interval, corrected QT interval (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd) have been reported in ESRD, but these results are variable and the influence of a hemodialysis is still controversial, In this study, we investigated the effect of hemodialysis on QT and QTc interval and QT and QTc dispersion in patients with ESRD 15 min before and 15 minute after each hemodialysis. Methods: Sixty-seven patients with ESRD (men 33 & women 34) on three-times stable hemodialysis (>3 months) were randomly enrolled. Fifty control subjects with a similar age and normal renal function were enrolled from this hospital. Routine biochemical studies were measured pre- and post dialysis, at the time of the ECG. Plasma Na+, K+, BUN, creatinine, ionized calcium and phosphate were checked. Twelve-lead electrocardiographs were performed at 10㎜/mv and 50㎜/s using a HewIett-Packard Pagewriter 100, before and after a single hemodialysis session.The QT interval was measured from the onset of the QRS complex to the end of the T wave. If the end of the T wave was not clear in a particular lead then it was excluded from analysis. When U waves were present, the end of the T wave was taken as the nadir between the T and U waves. Each QT interval was corrected for heart rate using Bazett's formula (QTc==QT/√(RR)) (ms). The difference between maximal and minimal QT interval duration was defined as QT dispersion (QTd) in each of the 12 leads. Result: This study demonstrates that QT, QTd, QTcd is higher in hemodialysis patients compared with control subjects, and QT and QTd rise postdialysis to levels comparable to those seen acutely following myocardial infarction, when patients are at greatly increased risk of potentially fatal ventricular arrhythmias, Conclusions: QT interval and QT dispersion, markers of risk for arrhythmias and sudden death, are elevated in hemodialysis patients, and rise postdialysis. QT interval and QT dispersion is an easily obtainable, noninvasive, simple, inexpensive, and widely available method of risk stratification in uremic patients receiving chronic dialysis. Additional studies are needed to clarity whether increased postdialysis QT dispersion results in an increased occurrence of arrhythmias.
대학생의 우울정도 : 간호학전공과 타전공대학생을 중심으로
김지연,류나은,이소라,이지희,정윤정,주지연,황인혜 이화여자대학교 간호과학대학 2012 이화간호학회지 Vol.- No.46
Purpose: This study was designed to investigate sample’s general characteristics and compare depression degree among sample’s general characteristics and students’ major(nursing vs. other major). Methods: The subjects consisted of 318 university students. Data was collected by self-reported questionnaires, which were constructed BDI score. Data was analyzed by the SPSS/PC WIN 19.0 program. Results: The depression of nursing students and other major students was not significantly different according to BDI score. Statistically significant difference was identified among sleeping. Conclusion: Specific study focused on the practice time should be done to confirm the depression of nursing major and other majors. Detailed support programs which specifically deal with sleeping should be developed to effectively reduce the harmful effects of individual vulnerability. Therefore, prevention and management system to reduce depression degree for university students is needed.
혈액투석중인 말기신부전 환자에서 Fludrocortisone acetate (FCA) 투여 후 혈청 칼륨 저하 효과
류봉관,강대웅,정지용,윤나라,신병철,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1
Background: Hyperkalemia is a commonly encountered problem in dialysis patients with end-stage renal disease. In this study we evaluated the effect of mineralocorticoid therapy (fludrocortisono acetate) on serum potassium level in the serum of hyperkalemic end-stage renal disease patients. Methods: Fourteen patients on hemodialysis receiving fludrocortisone acetate (FCA) 0.1 mg/day were observed for 2 months periods. Consecutive monthly biochemical profiles were compared for the druration of the pre-and post-treatment of FCA. Result: Fourteen patients with mean age (±SE) of 51.5 years (4 males and 10 females) and mean hemodialysis period of 51.9 months were studied. Mean serum potassium levels significantly fell (p<0.05) during the post-FCA period (5.2±0.66 mEq/L) compared with potassium levels during the pre-FCA (5.8±0.43 mEq/L) period. Pre-and post-FCA values were not different for sodium, chloride, protein, albumin, AST/ALT, glucose, blood nitrogen, creatinine, phosphate and calcium. Conclusions: FCA appears to decrease serum potassium value in patients with end-stage renal disease. These results suggested that FCA could be effective to treat hyperkalemia without any adverse effect in patients undergoing hemodialysis.
Scrub Typhus and Q Fever Coinfection: A Case Report
( Na-ra Yoon ),( Choon-mee Kim ),( Dong-min Kim ) 대한인수공통전염병학회 2019 창립총회 및 학술대회 초록집 Vol.2019 No.1
A 56-year-old female goat herder had scrub typhus that persisted even after receiving doxycycline for 5 days. Her symptoms continued, prompting us to perform further examinations that revealed coinfection of Q-fever and scrub typhus via genetic and serological testing. We also isolated Orientia tsutsugamushi using BALB/c mice and L929 cells. Q fever is a zoonotic infection caused by Coxiella burnetii. Although mammals, birds, and arthropods are all reservoirs of C. burnetii, ticks are known to be the main reservoir. The most common source of human infections is farm animals, including cattle, goats, and sheep [ Scrub typhus is a mite-born infectious disease caused by Orientia tsutsugamushi. The disease occurs predominantly in Asian Pacific Rim countries, including South Korea, China, Taiwan, Japan, India, Thailand, and Australia. To date, almost no study has reported coinfection of Q fever and scrub typhus. Here the patient with scrub typhus persisted even after received doxycycline for 5 days, her continuing symptoms prompted us to perform further examinations, in which we identified coinfection of Q-fever and scrub typhus molecularly and serologically. Additionally, we isolated O. tsutsugamushi. This report describes the details of the case.
알고리즘과 콘텐츠 창작에 관한 예술공학적 이해 : 〈월 드로잉 358번〉의 두 가지 버전을 중심으로
윤나라(Yoon, Na-Ra) 인문콘텐츠학회 2021 인문콘텐츠 Vol.- No.61
이 글은 정보기술과 예술이 분리 불가능할 정도로 서로 연관된 문화예술의 현재 상황을 반영한다. 정보기술에 기반을 둔 문화예술 콘텐츠 분야에서 기술에 관한 담론은 자주 오로지 실용적인 차원에서만, 혹은 반대로 오직 메타적인 층위에서만 이루어지곤 한다. 그러나 동시대 문화예술과 정보기술의 관계를 ‘작업 과정’을 중심으로 사유하다 보면, 콘텐츠를 창작하는 과정과 알고리즘적 사고 간에 현저한 유사점이 있음을 발견한다. 이를 조명하기 위해 이 글에서는 예술공학적 관점에서 알고리즘을 설명하고, 이것의 대표적 사례로서 솔 르윗의 〈월 드로잉 358번〉과 아티스트이자 프로그래머인 케이시 리아스에 의해 소프트웨어로 이식된 정보기술 버전의 〈358번〉을 비교분석한다. 이를 통해, 이 글은 예술의 창작 과정과 정보기술의 작업 과정이 알고리즘의 설계와 실행이라는 측면에서 대단히 유관함을 드러내 밝히고자 한다. This article aims to ponder the importance of information technology in the process of artistic creation with an emphasis on algorithmic thinking. Despite the inextricable link between the art and the information technology, discourses on information technology in relation to art is often conducted only at a merely practical level or, conversely, only at an overly metatheoretical level. However, if we rigorously consider the relationship between art and information technology, with a particular emphasis on the artistic creation "process", we can easily find that there are considerable similarities between the process of artistic creation and algorithmic thinking. To exemplify this, this article explains algorithm as well as algorithmic thinking from an art-tech point of view by taking two versions of 〈Wall Drawing #358〉 as representative examples: one by Sol LeWitt himself; another by Casey Reas implemented in software in 2004.