Characterizations of Modified Silica Nanoparticles(I)

Min, Seong-Kee,Park, Chan-Young,Lee, Won-Ki,Seul, Soo-Duk Materials Research Society of Korea 2012 한국재료학회지 Vol.22 No.6

(3-mercaptopropyl)trimethoxysilane (MPTMS) was used as a silylation agent, and modified silica nanoparticles were prepared by solution polymerization. 2.0 g of silica nanoparticles, 150 ml of toluene, and 20 ml of MPTMS were put into a 300 ml flask, and these mixtures were dispersed with ultrasonic vibration for 60 min. 0.2 g of hydroquinone as an inhibitor and 1 to 2 drops of 2,6-dimethylpyridine as a catalyst were added into the mixture. The mixture was then stirred with a magnetic stirrer for 8 hrs. at room temperature. After the reaction, the mixture was centrifuged for 1 hr. at 6000rpm. After precipitation, 150 ml of ethanol was added, and ultrasonic vibration was applied for 30 min. After the ultrasonic vibration, centrifugation was carried out again for 1 hr. at 6000rpm. Organo-modification of silica nanoparticles with a ${\gamma}$-methacryloxypropyl functional group was successfully achieved by solution polymerization in the ethanol solution. The characteristics of the ${\gamma}$-mercaptopropyl modified silica nanoparticles (MPSN) were examined using X-ray photoelectron spectroscopy (XPS, THERMO VG SCIENTIFIC, MultiLab 2000), a laser scattering system (LSS, TOPCON Co., GLS-1000), Fourier transform infrared spectroscopy (FTIR, JASCO INTERNATIONL CO., FT/IR-4200), scanning electron microscopy (SEM, HITACHI, S-2400), an elemental analysis (EA, Elementar, Vario macro/micro) and a thermogravimetric analysis (TGA, Perkin Elmer, TGA 7, Pyris 1). From the analysis results, the content of the methacryloxypropyl group was 0.98 mmol/g and the conversion rate of acrylamide monomer was 93%. SEM analysis results showed that the organo-modification of ultra-fine particles effectively prevented their agglomeration and improved their dispensability.

조직 구성원의 비윤리적 행위에 대한 도덕적 용인의 조절효과 분석

민기 ( Min¸ Kee ),박철민 ( Park¸ Cheol-min ) 대한정치학회 2021 大韓政治學會報 Vol.29 No.3

행정서비스의 수준은 행정의 주체인 공무원들의 의식 여하에 따라서 좌우됨은 재론을 요하지 않는다. 선후진국을 통틀어 정도 차이는 있어도 관료들은 공복으로서 사명감이 부족할 뿐 아니라 국가에 따라서 부정과 부패의 온상으로 여겨지기도 한다. 본 연구는 공무원들의 비윤리적 행위의 억제는 행정 능률성에 직결된다는 판단하에, 부산 지역 근무 공무원들을 대상으로 비윤리적 행위에 영향을 미치는 변수, 크기 및 조절 변인 분석에 목적을 둔다. 그간 조직 성과에 영향을 미치는 변수들에 대해서는 다수 연구들이 이루어져 왔지만, 처벌, 비윤리적 행위 등 부정적인 행동 변수들간 관계에 대해서는 그다지 많은 연구가 이루어지고 있지는 않다. 이 연구는 현재의 통제 지향적 관리체제하에서 그 동안 경시되어 온 비윤리적 행위 등 부정적인 행동을 억제하는 것이 조직 성과 제고 나아가 조직 혁신의 중요 과제라는 가정하에, 변인들간의 관계를 실증 분석하는 데 목적을 두었다. 분석 결과, 원인변수인 처벌 및 동료는 도덕적 용인과 비윤리적 행위의 중요 영향 변인의 역할을 수행하는 것으로 나타났다. 동시에 도덕적 용인은 원인변수인 처벌 및 동료를 자극하여 비윤리적 행위를 더욱 감소시키는 것으로 나타나서 이들 사이에서 조절변수로서 기능하는 것이 확인되었다. 본 연구는 외생변인들을 처벌, 동료에 한정한 한계는 있지만, 구성 변인들이 요인분석을 통해서 체계적으로 구성되었으며, 비윤리적 행위에 미치는 영향 변인들을 실증분석을 통해서 규명함으로써 분석 결과의 합리화를 추구하고 있는 점에서 연구 가치가 있는 것으로 본다. Nowdays, moral approbation and unethical behavior are expected to negatively related each other, and effect many highly valued organization outcomes in various work contexts respectively. Many previous studies support the belief by suggesting that unfavorable unethical behavior is negatively concerned with organization effectiveness as well as organization competitiveness, members’ job satisfaction, and quality of life. In spite of the discording role of the unethical behavior and moral approbation on organization outcomes, the relative contribution of the two concepts to organization outcomes has not been fully tested yet. Suggesting the relationship between antecedents and outcome variable, ie, punishment, colleague, moral approbation, and unethical behavior, therefore, this study analyzed the relationship between the constructs of over 238 public employees working in Busan City of Korea. Findings based on the moderating regression analysis supported the significantly negative impact between antecedents(punishment, colleague), and unethical behavior with moral approbation as a moderating variable.

Simulated Moving Bed를 이용한 Bupivacaine 키랄분리 : (1) Preparative Chromatography를 이용한 기본조건 결정 (1) Optical Separation Conditions for Preparative Chromatography

윤지연,이중기,서성섭,최민호,박태진 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.6

Racemate Bupivacaine의 키랄분리를 위한 크로마토그래피의 최적분리조건을 조사하였다. Kromasii^(�) 키랄고정상에서 최적이동상조성 성분은 n-hexane/2-propanol/acetic acid/triethylamine, 99/1/0.3/0.05(vol.%)이였다. 이동상 조성성분인 2-propanol의 부피비가 증가할수록 체류시간과 분리도가 동시에 감소되었다. 이동상 성분 중에서 미량으로 존재하는 triethylamine이 증가할수록 피크의 sharpness가 증가하고 체류시간 역시 감소하였다. 또한, acetic acid가 없으면, 크로마토그래피 광학분할이 불가능하였으며 부피 0.3%에서 분리도가 가장 높음을 확인할 수 있었다. 한편, 키랄의약품의 대량분리방법중의 하나인 SMB(simulated moving bed)크로마토그래피 시스템(직경 1.0cm×10cm×8개 칼럼으로 구성)의 최적분리조건을 전산모사에 의해 구하였으며, 이를 실험으로 확인하였다. 그 결과 switching time 15분, feed의 유량 0.1 ml/min, desorbent 0.86 ml/min, raffinate 0.3 ml/min, extract 0.66 ml/min, recycle 1.0 ml/min일 때 100% 순도의 R-form과 S-form을 얻을 수 있었으며, 실험치와 전산모사치간의 오차는 ??2%이내였다. The chiral separation of racemate Bupivacaine was carried out to find the optimum condition for chromatographic system. The optimum species and composition for mobile phase were n-hexane/2-propanol/acetic acid/triethylamine, 99/1/0.3/0.05(vol.%) in case Kromasil� chiral stationary phase was employed. The retention time and resolution decreased with the increase in the ratio of 2-propanol in the mobile phase. The sharpness of peak and retention time decreased, as the content of triethylamine increased. Without the existence of acetic acid, the chromatographic separation didn't occur, and the resolution was the highest at the acetic acid volume ratio of 0.3%. The optimum condition of SMB (simulated moving bed) was determined by simulation and its results was compared with exprimental data from lab-scale SMB (10 mm 1D×8 ea). Rased on the SMB simulation and experimental results, 100% purity of R and S Bupivacaine were obtained and the error between the calculated and experimental value was within ±2%.

간질환환자의 위내용물 배출시간에 관한 연구

함준수(Joon Soo Hahm),이동후(Dong Hoo Lee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),기춘석(Choon Suck Kee),유대현(Dae Hyun Yoo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2

N/A Gastric emptying time(GET) is influenced by several factors, such as neura), hormonal and composi- tion and physiochemical properties of food. The patients with delayed GET have some upper gastrointestinal symptoms such as recurrent nausea, vomiting, postprandia! Bloating, anorexia, and iveight loss. And also, almost of acute hepatitis and a part of chronic ]iver disease patients have similar symptoms of the patients with delayed GET. Therefore We performed GET measurement in liver disease patients to identify the relationship between nonspecific upper gastrointestinal symp- toms and gastric emptying function. The resu]ts are as followings; 1) Total ]iver disease patients are 28 in number, composed of acute hepatitis 3, chronic hepatitis 18, liver cirrhosis 7. 2) The GET(T1/2) of liver disease patients was delayed significantly than that of the normal volunteers. (Mean+SE;120.8+6.6 vs 89.4+5.9 mins.) 3) The GET of the symptomatic patients (N = 20 ) ivas 128.3+6.8 mins (Mean+SE), and that of the asymptomatic patients (N =8) was 101.8+13.2 mins. The symptomatic patients have delayed GET in 10 patients and asymptomatic patients have delayed GET in 3. 4) The GET of the patients who have elevated serum transaminase level higher than twice of normal is delayed significantly than that of the patients who have serum transaminase level lower than twice of normal. (Mean+SE; 143.4+2.6 vs 110.0+7.4 mins.)

풍동시험에서 사용하는 시험지지부의 동특성 해석용 툴에 관한 연구

박태민,이기석,홍준희 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

This paper is described the program algorithm which can easily estimate dynamics of test support system by using mathematica tool based on the finite element method. We can determine the geometry, dimensions of the test support system, through tool stated in this paper for a certain test conditions. As a result of computer simulation and manufactured test support system's experiment in oder to verify suggested program, the dynamics of the test support system was well correspondent each other.

췌십이지장절제술 후 발생한 지속적인 구토증과 Wernicke 뇌병증

박우영,김성완,이삼연,신일선,김재민,박기형,양수진,윤진상 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.3

Wernicke encephalopathy is an acute neurologic disorder attributable to thiamine (vitamin B1) deficiency. We report the case of a 61-year-old female patient who presented Wernicke encephalopathy after surgery for pancreatic head cancer. From the ninth postoperative day, she had suffered from nausea and vomiting and had difficulties ingesting food, she was given total parenteral nutrition (TPN), but lacked adequate vitamin (thiamine) supplementation. After 28 days, she developed ataxia, ophthalmoplegia, and mental confusion. The magnetic resonance image showed pathologic changes in the medial thalamus,periaqueductal gray matter, medulla and mamillary bodies. The blood level of thiamine was very low. After intravenous and oral supplementation of thiamine (200 mg/day), consciousness was soon normalized and neurologic symptoms have gradually been improving. Nausea and vomiting disappeared after administration of a low dose of mirtazapine (7.5 mg/day). We emphasize the importance of thiamine supplementation to the patients who suffer from vomiting which hinders them from taking food and who require prolonged TPN.

대학생의 개인재무관리역량

이슬기, 박현정, 김민정 충북대학교 생활과학연구소 2012 생활과학연구논총 Vol.16 No.1

The purpose of this study is to measure financial competency of students in Chung-buk national university. The financial competency included financial attitude, financial knowledge, and financial skills. The major findings are as follows: First, as the financial management competency of university students, their attitude towards financial management was 75 points, knowledge in financial management was 68.5 points, and financial management skill was 59.9 points. Second, male students showed higher scores than female students in all areas. Third, students in the fields of medicine, education, and laws showed higher levels of financial management knowledge yet their financial management skill was low. Forth, students who receive allowances from parents showed high points of attitude towards financial management yet their financial management skill was low. Those who receive allowances from people that are not parents showed lower points in the attitude towards financial management or the knowledge than those who do not receive allowances. Fifth, students who spend money they earned showed higher points in every area than other students’ points. Finally students who received financial education showed similar or lowered points in financial management attitude and financial management knowledge with students who did not receive the financial education. However, the level of their financial management function was higher. Students who have saving accounts, periodicaldeposits, fixed deposits, a check card, or debit card showed higher levels of financial management knowledge and function that those who do not have the above items.

영상처리시스템을 이용한 아크용접 로보트의 자기교시법

박민기,박민용,김문주 연세대학교 산업기술연구소 1993 논문집 Vol.25 No.2

In this paper, a new method of sensing the welding line of a workpiece is proposed. We use a CCD camera as the sensor and two-dimensional welding line of the workpiece is obtained by processing and scanning the image. Using the welding line and extended chain code, the information of welding line is obtained and stored, so the self-teaching is done. Finally, we prove that this self-teaching method is available to a welding robot by an experiment.

만성 호중구성 백혈병 1예

박기령,조성민,우가은,이기현,손혜영,임정윤,최진혁,이순남,정화순 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.2

Chronic neutrophilic leukemia(CNL) is a very rare myeloproliferative disease, characterized by sustained mature neutrophilic leukocytosis with granulocytic bone marrow infiltration, high NAP(neutrophilic alkaline phosphatase) score and absence of philadelphia chromosome, It is frequently accompanied by hepatosplenomegaly, elevated serum vitamin B_12 and uric acid level. For the diagnosis of CNL, the leukemoid reaction, especially secondary to neoplasia, infection and autoimmune diseases, should be excluded. Since Tuohy's first description in 1920, more than 50 cases fullfilling the above criteria have been reported worldwide, and 4 cases in Korea. Several authors have demonstrated the defect of intracellualr killing in the mature neutrophil and this finding correlates well with the very high incidence of fatal infection, The hemorrhagic diasthesis in CNL is caused by functional abnormality of the platelet. This disease has tendency to transform to blastic crisis and acute leukemia as in other myeloproliferative disease, but characteristically shows frequent coexistence with multiple myeloma. Until now , the therapeutic trials in CNL have been disappointing. Hydroxyrea and busulfan can control hyperleukocytosis. On the basis of functional defect in neutrophil, alpha-2b-interferon has been tried and several reports have demonstrated the clinical and functional effect of interferon on CNL. CNL is very rate hematologic disease and there are few report about general aspect of disorder. We report here a typical CNL case presenting with splenomegaly and leukocytosis with a review of the literature.

甲狀腺 홀몬의 受容體에 關한 硏究

李民化,安鳳煥,李起榮,朴鐘一 全南大醫大 1980 전남의대학술지 Vol.17 No.1