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      • A Study on the appropriate herbal medicine according to Sasang constitution using EAV

        Choi,Jin-Wook,Lee,Su-kyung,Hong,Suck-chull,Koh,Byung-hee INSTITUTE OF ORIENTAL MEDICINE KYUNG-HEE UNIVERSIT 1997 JOURNAL OF ORIENTAL MEDICINE Vol.2 No.1

        1. Objective This is a basic study about the response of herbal medicine to EAV. The purpose was to investigate how the meridian of EAV responded to herbal medicine and how EAV was applied to the diagnosis of Sasang constitution. 2. Materials & Methods The subjects of this study were patients who were being treated in the Dept. of Constitutional Medicine ot Kyung-Hee Medical Center. The study examined how herbal medicine affected the maximum value and the indicator drop and how each constitution responded differently to the constitutional herb medicine. 3. Results & Conclusions 1) When comparing the maximum value and ID of the worst BAP before and after the experiment with herbal medicine, the maximum value significantly went up and the ID significantly went down in all the herbal medicines. So we confirmed that all the herbal medicines positively affected the change of the maximum value and ID. 2) The changes in the maximum value induced by herbal medicines were significantly different according to the constitution of Dokhual Jihwang Tang, and Hyangbuja Palmul Tang. Although Dokhual Jihwang Tang was soyangin's herb medicine in Sasang constitutional medicine, it raised the value of soeumin higher than that of soyangin. Hyangbuja Palmul Tang which was soeumin's herb medicine raised the value of soeumin higher than that of the other constitution. 3) The changes of ID were not significantly different in the constitution.

      • KCI등재후보

        삼일열 말라리아에 합병된 비장 파열 1예

        홍경욱,이정아,김원진,박철민,권혜리,박혜원,엄중식 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

        국내의 토착형 말라리아는 삼일열 말라리아로, 1993년부터 재유행이 시작되었다. 말라리아의 중요한 합병증으로 드물지만 비장 파열이 있는데, 이는 주로 삼일열 말라리아에 의해서 발생되며, 국내에서는 1999년 말라리아에 의한 비장 파열로 비장 절제술을 시행한 예가 보고된 바 있다. 현재까지는 비장 파열이 있을 때 비장 절제술이 일차적인 치료로 되어 있으나, 비장 절제술 후의 감염 위험성이 크므로, 활력 징후가 불안정하거나, 출혈이 지속되는 소견이 보이지 않으면 가급적 보존적 치료를 하는 것이 추천된다. 저자들은 비장 파열이 동반된 말라리아 환자에서 비장 절제술을 시행하지 않고 보존적 치료로 호전된 예를 경험하여 보고하는 바이다. Plasmodium vivax has been the predominant Plasmodium species in the Republic of Korea and reemerged in 1993. Spontaneous rupture of malarial spleen is a rare but important complication associated with P. vivax infection. Only one case of spontaneous rupture of malarial spleen was reported in Korea in 1999. Splenectomy is still accepted as the treatment of choice in cases of spontaneous rupture of the spleen. But, considering increased risk of postsplenectomy infecion, splenectomy should be reserved for those patients with severe rupture or those with continued or recurrent bleeding. And conservative treatment should be considered in selected, closely monitored patients. We report a patient with P. vivax malaria who developed a spontaneous splenic rupture and was improved by conservative treatment.

      • KCI등재후보

        자돈에 있어 게르마늄 용질액의 급여가 성장 및 혈액학적 변화에 미치는 영향

        홍종욱,권오석,민병준,조진호,진영걸,손경승,강종옥,김인호 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4

        본 연구의 목적은 이산화게르마늄을 함유한 게르마늄 용질액을 자돈에 급여하였을 때 성장 및 혈액학적 변화에 미치는 영향을 조사하기 위하여 실시하였다. 3원 교잡종 자돈 60두 (평균체중 11.22±0.10㎏)를 공시하였다. 시험설계는 옥수수-대두박 위주의 대조구(CON)와, 대조구 사료내 게르마늄 용질액을 0.5 ppm 첨가한 구(GC0.5) 및 대조구 사료내 게르마늄 용질액을 1.0 ppm 첨가한 구(GC1.0)로 3개 처리를 하였다. 0-10일간 사양시험기간동안, 일당증체량에 있어서 GC0.5 처리구가 약간 높게 평가되었다(quadratic effect, P<0.02). 그러나 전체 시험기간동안, 일당증체량, 일당사료섭취량 및 사료효율에 있어서 처리구간에 유의적인 차이는 보이지 않았다. 영양소 소화율에 있어서는 GC0.5 처리구가 조회분(linear effect, P<0.01; quadratic effect, P<0.04), 칼슘(linear effect, P<0.01; quadratic effect, P<0.01), 인 (linear effect, P<0.02; quadratic effect, P<0.04) 소화율이 유의적으로 높게 평가되었다. 혈액내 neutrophil 농도에 있어서는 게르마늄 용질액의 첨가 수준이 증가함에 따라 유의적으로 증가하는 경향을 나타내었다(quadratic effect, P<0.02). 결론적으로, 자돈 사료내 게르마늄 용질액의 급여가 성장 및 혈액학적 수치에는 영향을 미치지 못하는 것으로 사료된다. This study was conducted to investigate the effects of dietary germanium colloid on the growth performance and hematological values in nursery pigs. Sixty pigs (11.22(0.10 ㎏ average initial body weight) were used in a 20 d growth assay. Dietary treatments included 1) CON (basal diet), 2) GC0.5 (basal diet+0.5 ppm germanium colloid) and 3) GC1.0 (basal diet+1.0 ppm germanium colloid). For d 0 to 10, pigs fed GC0.5 diet grew faster than pigs fed CON and GC1.0 diets (Quadratic effect, P<0.02). However, through the entire experimental period, no statistical differences were found for aver-age daily gain, average daily feed intake and gain/feed. Apparent digestibilities of crude ash (Linear effect, P<0.01; Quadratic effect, P<0.04), calcium (Linear effect, P<0.01; Quadratic effect, P<0.01) and phosphorus (Linear effect, P<0.02; Quadratic effect, P<0.04) in pigs fed GC0.5 diet were greater than for pigs fed CON and GC1.0. Neutrophil concentration in blood increased as the concentration of germanium colloid in the diets was increased with significant difference (Quadratic effect, P<0.02). In conclusion, growth performance and hematological values were not influenced by dietary germanium colloid.

      • 백서에서 동종 신경이식시 항 T임파구 단일클론항체 분포에 관한 조직화학적 연구

        홍창섭,김경욱,임창준,정대현 단국대학교 치의학연구소 1991 논문집 Vol.3 No.-

        Nerve allografts as a bridge through which lost nerve can regenerate is useful in the repair of peripheral nerve defect resulting from trauma, neoplasm and leprosy. But immunological rejection and complicated scar formation is an unaboidable problem in the application of allogenic nerves. This article is intended to study histopathological and immunohistochemical response after fresh allogenic sciatic nerve grafts in rats. 12 male Sprague- Dawley rats were used as the experimental animals. A 2cm skin incision was made on the lateral aspects of limb, parallel to the femur. 1cm-long sciatic nerve trunk taken from the one rat was resected at the middle of the to high, and it was transplanted to the same area of the other rat with perineural suture method. Observation was made at the postoperative 1, 3, 8, 16 day. The results were as follows. 1. Histopathologically, destruction of the perineural sheath was observed only in 1-day group. 2. Mild degenerative changes of the nucleus and cytoplasm of Schwann cells were ovserved in the 1-day and 3-day groups. These changes gradually resolved. 3. Hollow space phenomena of the nucleus and cytoplasm of schwann cells were observed. The response was mild in the 1 day and 3 day groups, and moderate in the 8 day group. The phenomena were not identified in the 16 day group. 4. Immunohistochemical studies revealed pan T cells and cytotoxic T cells in the 1 day group. Increased numbers of cytotoxic T Cells and helper T cells were observed in the 3 and 8 day groups. 5. According to these results, after transplantation of fresh allogenic sciatic nerve an inflammatory response was observed up to 8 days and then gradually resolved. Degenerative changes were more severe up to 8 days, but an the 16th day they had resolved histopathologically and immunopathologically.

      • SCIESCOPUSKCI등재
      • 서울의 PPNG 발생 빈도(1991-1992)

        김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

        The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

      • 高效率 시리콘 太陽電池의 硏究 : Ti/p-Si, MIS Inversion and Heterojunction Type Solar Cells Fabricated by Bacuum Evaporation and Spray Pyrolysis Methods

        羅炳旭,李相潤,朴德圭,李鍾德,禹洪,盧景錫 慶北大學校 物理化學硏究所 1982 硏究論文集 Vol.3 No.-

        1. Ti/p-Si Solar cell Fabricated by Vacuum Evaporation Titanium thin film was deposited on the chemically etched (100) surface of silicon single crystal by the vacuum evaporation. The interfacial oxide was grown by ramp heating. The Ti/p-Si solar cells have shown good rectification properties with the 0.78 V built-in potential and the 20 ㎂/㎠ reverse saturation current density in dark. The best cell have 0.58 V open circuit voltage, 38.0 ㎃/㎠ short circuit photocurrent density 0.64 fill factor and 13.9 % energy conversion efficiency under 100 ㎽/㎠ tungsten halogen lamp irradiation. Therefore, this solar cell is a very promising one, but the life testing is not performed yet in out laboratory. 2. Al/p-Si Solar Cell with Fine Grid and Inversion Layer The fabrication procedure and properties of MIS inversion solar cells forming a fine grating pattern of aluminium evaporated onto p-type silicon single crystal are discribed. The finest grating line width achieved in these cells described here were about 30 ㎛, and the smallest spacings were about 120 ㎛. The proper temperature for oxide growing of these cells was found to be about 450℃ for 20 minutes with oxygen flow. Under 100 ㎽/㎠ of irradiation of sunlight and using the antireflective coating of tnataliumsilicafilm spun on these cells, the short circuit photocurrent density, open circuit voltage and energy conversion efficiency were 28.0 ㎃/㎠, 0.545 V and 11 % respectively. 3. Heterojunction Type Solar Cell In_2O_3: Sn and SnO_2 films were deposited on the (100) surface of silicon single crystal by the spray pyrolysis method. The properties of these cells have good rectification with open circuit voltage, the short circuit photocurrent density, fill factor and energy conversion efficiency of 0.52V, 39.3㎃/㎠, 0.63 and 12.9 %, for In_2O_3: Sn/n-Si heterojunction solar cell and of 0.45V, 35.5 ㎃/㎠, 10.2%, for SnO_2/n-Si cell, respectively.

      • SCIESCOPUSKCI등재
      • 백서 복강내 근간극에 매식된 동결건조 탈회골 분말과 섬유소 혼합물의 신생골 형성에 관한 실험적 연구

        김홍진,임창준,김경욱 단국대학교 치의학연구소 1993 논문집 Vol.5 No.-

        Various forms of bone graft materials have been used for reconstruction of the congenital malformations, acquired deformities after tumor surgery trauma, or physiologic bone resorption following absence of teeth in the oral and maxillofacial region. Van Meekren was the first one to report bone grafting. Senn transplanted demineralized bovine bone to for the clinical purpose. In 1960s, Urist reported osteoinduction in the demineralized bone embedded in the extraskeletal sites. Thereafter Reddi, Huggins, Sharawy, Glowacki, Kaban, Mullikan, and others reported the experimental and clinical reports of potentiality of the demineralized bone. In the recent clinical parctice, there are many cases using dimineralized freeze-dried bone powder (DFBPO, with various forms of occlusive barriers or adhesives as a carrier, were used for the bone regeneration. The purpose of this experiment is to find out whether fibrin clot can be used as a carrier for DFBP. We used saline-rehydrated DBP in control group rats and saline-reconstituted DFBP mixed with fibrin in experimental group and sacrifice the rats at postoperative 3 days, 1 week, 2 weeks, 4 weeks, and 6weeks. We stained the demineralized samples with HE staining and the undemineralized samples with Villanueva staining and the samples was observed under the light microscope. The results were as follows. 1. The amount of the early mesenchymal tissue ingrowth at the third day specimen of the experimental group was similar to that of the 1st week control group. 2. The blood cells were found in the specimen at the postoperative third day in both of the experimental groups and the control groups. 3. Osteoid matrix surrounding the graft materials were observed from the postoperative 4th week in both of the experimental groups and the control groups. 4. Bone remodelling was observed from the postoperative 4th week in both of the experimental groups and the control groups.

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