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An Efficient Implementation of LDPC Decoder with Partial Parallel Algorithm for DVB-S2 System
Suksoon Choi1,Minhyuk Kim,Jongtae Bae,Taedoo Park,Namsoo Kim,Jiwon Jung 대한전자공학회 2008 ITC-CSCC :International Technical Conference on Ci Vol.2008 No.7
In this paper, we investigate the encoding and decoding method of the irregular LDPC (Low Density Parity Check) codes that offer diverse coding rates from 1/2 to 9/10 defined in the Digital Video Broadcasting (DVB-S2) standard. We study the efficient memory assignment and the implementing method in the LDPC codes.
Jiwon Choi(Jiwon Choi),Keesin Jeong(Keesin Jeong),Haiyoung Jung(Haiyoung Jung) 한국화재소방학회 2022 International Journal of Fire Science and Engineer Vol.36 No.4
Dust and fine dust exist in various forms and can lead to various problems such as dust explosion and air pollution. To reduce them, recently, research on electrospray electric precipitation, among various dust collection methods, has been actively conducted. In this study, comparative analysis experiments were performed on microdroplet generation characteristics for direct and indirect charging methods of electrospray electric precipitation. A visualization device was fabricated to generate microdroplets, and microdroplets were photographed with a high-magnification camera according to each charging method. The size and number of microdroplets were then analyzed via ImageJ software.
Young Children’s Metacognition Expressed during Coding Play
Han Jiwon(Jiwon Han),Choi Younchul(Younchul Choi) The Pacific Early Childhood Education Research Ass 2023 Asia-Pacific journal of research in early childhoo Vol.17 No.3
The purpose of this study is to explore young children’s metacognition expressed during coding play. The children participating in this study consisted of 13 five-year children(6 males and 7 females) at H Kindergarten in S City. Various data, such as observation records, researcher’s own journals, and informal consultation meeting records were collected and analyzed. The results of this study are as follows: First, metacognitive planning can be further activated in coding play while children create their own meaning through judgment and selection. Second, children are engaged in monitoring the degree to which performance is progressing towards a desired goal. Third, metacognitive control actively appeared in coding play while children changed ways of conducting tasks. Fourth, children review task performance and evaluate the quality of performance in coding play. The results of this study are expected to help understand how young children’s metacognition appears in coding play, and further reveal the educational value of coding play that helps young children activate their metacognition.
1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists
Choi, Jiwon;Park, Yunsun;Lee, Hui Sun;Yang, Young;Yoon, Sukjoon Sookmyung Women's University Research Institute of 2011 여성과 건강 Vol.6 No.2
A new series of PPARγ partial agonists, 1,3-diphenyl-1H-pyrazole derivatives, were identified using an improved virtual screening scheme combining ligand-centric and receptor-centric methods. An in vitro assay confirmed the nanomolar binding affinity of 1,3-diphenyl-1 H-pyrazole derivatives such as SP3415. We also characterized the competitive antagonism of SP3415 against rosiglitazone at micromolar concentrations. They showed a PPARγ partial agonistic activity similar to that of a known PPARγ drug, pioglitazone. in a cell-based transactivation assay. Furthermore, the structure-activity relationships of the pyrazole derivatives were investigated through comparative molecular field analysis and binding mode analysis, which provided new insight concerning their partial agonistic effect on PPARγ.
3',4'-Dihydroxyl Groups in Luteolin are Important for Its Inhibitory Activities against ADAMTS-4
Jiwon Choi,정기웅,Jin-Kyoung Kim,Byung Ha Chang,Jee-Young Lee,김양미 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.9
A disintegrin and metalloprotease with thrombospondin domains (ADAMTS) are a member of peptidase and involved in processing of von Willebrand factor as well as cleavage of aggrecan, versican, brevican and neurocan. Among 19 subfamilies of human ADAMTS, ADAMTS-4 is a zinc-binding metalloprotease and is a famous therapeutic target for arthritis. It has been reported that a flavonoid luteolin shows inhibitory activity against ADMATS-4. In this study, we verified that luteolin is a potent inhibitor of ADAMTS-4 and probed the molecular basis of its action. On the basis of a docking study, we proposed a binding model between luteolin and ADAMTS-4 in which 3',4'-dihydroxyl groups in luteolin formed hydrogen bonding with ADMATS-4 and these interactions are important for its inhibitory activity against ADAMTS-4..
Jiwon Choi,Jayong Chung 한국영양학회 2023 Journal of Nutrition and Health Vol.56 No.6
Purpose: Baicalein, a natural flavone found in herbs, exhibits diverse biological activities. Nonalcoholic steatohepatitis (NASH) is an irreversible condition often associated with a poor prognosis. This study aimed to evaluate the effects of baicalein on the development of NASH in mice. Methods: Male C57BL/6J mice were randomly divided into four groups. Three groups were fed a methionine-choline-deficient (MCD) diet to induce NASH and were simultaneously treated with baicalein (at doses of 50 and 100 mg/kg) or vehicle only (sodium carboxymethylcellulose) through oral gavage for 4 weeks. The control group was fed a methionine-choline-sufficient (MCS) diet without the administration of baicalein. Results: The baicalein treatment significantly reduced serum levels of alanine aminotransferase and aspartate aminotransferase, suggestive of reduced liver damage. Histological analysis revealed a marked decrease in nonalcoholic fatty liver activity scores induced by the MCD diet in the mice. Similarly, baicalein treatment at both doses significantly attenuated the degree of hepatic fibrosis, as examined by Sirius red staining, and hepatocellular death, as examined by the terminal deoxynucleotidyl transferase dUTP nick end labeling assay. Baicalein treatment attenuated MCD-diet-induced lipid peroxidation, as evidenced by lower levels of hepatic malondialdehyde and 4-hydroxynonenal, demonstrating a reduction in oxidative stress resulting from lipid peroxidation. Moreover, baicalein treatment suppressed hepatic protein levels of 12-lipoxygenase (12-Lox) induced by the MCD diet. In contrast, baicalein enhanced the activities of antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. Additionally, baicalein treatment significantly reduced hepatic non-heme iron concentrations and hepatic ferritin protein levels in mice fed an MCD diet. Conclusion: To summarize, baicalein treatment suppresses hepatic lipid peroxidation, 12-Lox expression, and iron accumulation, all of which are associated with the attenuation of NASH progression.
Effect of Aging on Speech Discrimination
Choi Jiwon,Kim Taeho,Kim Sunhong,Kim Yoonho,Kim Dong-Kee 대한청각학회 2022 Journal of Audiology & Otology Vol.26 No.4
Background and Objectives: The aim of this study was to investigate the factors associated with decrease in speech discrimination ability seen in patients with presbycusis and whether aging has a significant effect on the observed decline.Subjects and Methods: We retrospectively analyzed the medical records of patients aged >40 years who had undergone pure-tone audiometry, speech audiometry, and auditory brainstem response for hearing loss at our hospital from January 2019 to June 2021, and investigated the factors that correlated with speech discrimination score.Results: We enrolled 103 patients with 120 ears, with a mean age of 65.8±11.9 years. The pure-tone average of the patients’ thresholds at 0.5, 1, 2, and 4 kHz was 37.2±27.7 dB HL, and their mean speech discrimination score was 82.5%± 22.3%. A correlation analysis revealed a significant negative correlation between the patients’ speech discrimination scores and age. In addition, all variables of pure-tone audiometry and the patients’ auditory brainstem responses were significantly correlated with the speech discrimination scores. The pure-tone average had the strongest negative correlation. On analyzing the significant predictors of lower speech discrimination scores, using a multiple linear regression analysis, pure-tone average and age showed significant results.Conclusions: The speech discrimination ability of older patients with hearing loss significantly decreases with increasing pure-tone average and age.
Jiwon Choi(최지원),Chanjoo Kim(김찬주),Yunhee Ko(고윤희),Hyeji Im(임혜지),Yoo-Jin Moon(문유진),Reid McLain(뤼드 맥클레인) 한국컴퓨터정보학회 2021 韓國컴퓨터情報學會論文誌 Vol.26 No.11
이 논문은 데이터 큐잉 알고리즘과 의약품 빅데이터를 통해 약품 성분-성분 간의 정보와 질병-성분 간의 정보를 지원함으로써 의약품 다약제 복용 시 부작용이 발생 가능한 약물 정보를 사용자에게 제공하기 위한 시스템을 제안하고 구현한다. 또한, 의약품 성분에 더하여 복용이 금지된 의약품, 공급업체, 유통업체의 정보 등을 제공함으로써 의료 전문가뿐만 아니라 일반 사용자의 의약품 복용에 대한 불안감을 덜어줄 수 있다. 제공되는 대표적인 정보는 두 가지 약물 사이에서 일어나는 부작용, 특정 의약품의 주성분과 효능, 동일한 제약회사에서 제조된 의약품, 만성 질환 환자가 주의해야 할 약품 성분 정보이다. 앞으로, 희귀병 약이나 신약에 대한 정보를 수집하여 데이터를 업데이트하는 것이 필요하다. In this paper, we designed and implemented the integrated system to prevent adverse drug reactions of polypharmacy components in medicine by supporting component-component information and disease-component information, through data queuing algorithm and vast amounts of pharmaceutical big data. In addition, by providing information for drugs, drug components, prohibited drugs, as well as suppliers and distributors, it could help ease anxiety about taking drugs not only for health-care professionals but also for general users. The representative information provided were side effects between two drugs, main components and effectiveness of particular drugs, drugs manufactured by the same pharmaceutical company, and drug component information for patients with chronic diseases. The future work is to update the database by collecting information on rare & new diseases and new drugs.