히스토아크릴을 이용한 십이지장 궤양 출혈의 지혈 후 발생한 급성췌장염

유재훈,문원,노지훈,구동영,조영화,김기수,윤준모 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

Upper gastrointestinal bleeding is common and potentially life threatening medical emergency. Emergency endoscopy is the first choice of diagnostic and treatment measure for patients with active upper gastrointestinal bleeding. Histoacryl should be considered a second-line treatment modality when conventional treatments were failed. However, it might cause several complications. Herein, we report a case of acute pancreatitis developed after histoacryl injection therapy for active duodenal ulcer bleeding. A 71-year-old man was admitted with melena and hematemesis. On emergency endoscopy, a 2 cm sized active ulcer with bleeding from an exposedvessel was seen at the duodenal bulb. Attempts to arrest the bleeding with hemoclipping and submucosal epinephrine injection were tried, but failed. We changed the method to endoscopic histoacryl injection, and obtained hemostasis immediately. A few hourslater, after successful hemostasis, patient complained diffuse abdominal pain. Ultrasonography revealed hyperechoic heterogenous diffuse pancreatic enlargement and right pararenal space fluid collection, this ultrasonographic findings and elevated serum pancreatic enzymes are compatible with acute pancreatitis.

벼 무논골뿌림裁培時 播種期가 生育 및 收量에 미치는 影響

池在浚,朴裁成,朴成圭,李尙榮,洪性澤,孫錫龍 충북대학교 농업과학기술연구소 1999 農業科學硏究 Vol.16 No.-

This study was carried out to determine the optimum seeding date for the rice(Oryza sativa L.) cultivation of the puddled-soil drill seeding, which is one of the efficient labor saving cultural methods, at the central part of Korea. Namweonbyeo, Anjungbyeo and Ilpumbyeo were seeded on four dates from April 10 to May 25, 1994 with the 15 day interval in the paddy field. In order to examine the adequate seeding date, the growth characters, yield components and yields were investigated. The coleoptile emerged 1 or 2 days earlier in Namweonbyeo than in Anjungbyeo and Ilpumbyeo, and later seeding resulted earlier coleoptile emergence. The number of seedling stands were higher in the order of Namweonbyeo, Anjungbyeo and Ilpumbyeo, was increased at the later seeding and was 81 to 88 seedlings on April 10 seeding. The plant height, number of leaves, number of tillers and dry weight at 50 days after seeding of all three cultivars were higher at later seeding. Leaf area index(LAI) were higher in the order of Ilpumbyeo, Anjungbyeo and Namweonbyeo. LAIs at the heading stage, at 30 days after heading and at 30 days before heading were higher in that order. The dry matter weight at the 30 days before heading was higher in sheath and stem than that in leaf blade, while, at heading stage, it was higher in the order of sheath and stem, leaf blade and panicle. On the other hand, at 30 days after heading, it was higher in the order of panicle, sheath and stem and leaf blade. The number of panicles per m2 was greater in the order of Ilpumbyeo, Anjungbyeo and Namweonbyeo. The ratio of ripened grain was reduced as the later seeding date. Its ratio was higher in Namweonbyeo than in Anjungbyeo and Ilpumbyeo. Yield of Namweonbyeo was lower than those of Anjungbyeo and Ilpumbyeo. Yield was decreased as the seeding date was delayed. Namweonbyeo showed the highest yield at seeding on May 10, while Anjungbyeo and Ilpumbyeo showed at seeding on April 25. The seeding date was negatively correlated with the ratio of ripened grain. while the number of seedling stands was positively correlated with the number of panicle per m2.

CAT용 스펙트럼 분석기 모듈에 적용한 인터페이스 설계및 구현에 관한 연구

전동근,강지훈,김재형 國立 昌原大學校 産業技術硏究所 1992 産技硏論文集 Vol.6 No.-

As factory automation is rapidly propelled, automatic manufacturing facility is developing widely. But the development of ATE(Automatic Test Equipment) is not reached than that of it. In this paper, we designed intermodule interface for measurment device for computer and CAT(Computer Aided Test) for automatic testing device of spectrum analyzer and implemented real time processing program for control of measurement device. OOP(Object Oriented programming) technique was used in control program to be interfaced with other measurement equipment easily. And we constructed of GUI(Graphical User Interface) method that can be used softwere for user.

AB 슬라이드, 크런치 및 윗몸일으키기 운동이 복직근 근활성도에 미치는 효과 : Comparison of It `s Myoelectrical Activities with Crunch and Sit-Up

지송운,김호성,양윤준,장재원 대한스포츠의학회 2004 대한스포츠의학회지 Vol.22 No.1

The purpose of this study was to compare the effect of AB slide™ on abdominal muscles with Crunch and Sit-up. Myoelectrical activities of Rectus abdominis muscles produced by AB slide™, Crunch and Sit-up were recorded. Healthy male aged from 17 to 36 years(23.0±5.9 yrs) were included fo the test. Surface electrodes were attached to upper and lower part of Rectus abdominis of the study subjects. Averaged integrated electromyography(AIEMG) and Normalized integrated electromyography(NIEMG) were recorded. The results are summarized as follows; First, the AIEMG of Sit-up were highest among them with insignificant difference statistically. Second, the NIEMG of upper part of Rectus abdominis were higher than the one of lower part with significant difference statistically(p<0.05). This phenomenon was same irrespective of the type of exercises. AB slide™ was not more effective than Sit-up and Crunch for strengthening of Rectus abdominis muscle. The upper part of Rectus abdominis was more activated than the lower part by all three exercises.

토양환경지도 자료를 이용한 콩밭 토양의 화학성 비교

박지숙,이민진,정재원,김미혜,이서연,지윤미,한준호,김유학,공명석,한광현,노희명 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

It is important to interpret the soil chemical properties in order to effectively manage the farmland. This study was conducted to investigate the soil chemical properties of upland soybean field according to the soil series at 32 upland fields located in the parts of Gangwon-do. Soil sampling sites were selected by using the National Statistics DB and KSIS DB that is a soil environment information system provided by the Rural Development Administration. Soil samples were collected from 0~15 cm of top soil before seeding or transplanting, air-dried, passed through a 2 mm sieve, and analyzed for soil pH, EC, organic matter, available phosphorus (P2O5), exchangeable potassium, exchangeable calcium and exchangeable magnesium. The average chemical properties have exceeded the each nutrient optimum range level of RDA, except the organic matter in experimental soil 2015. And despite application of conventional fertilization, each soil series nutrient contents were change respectively. The results of this study suggest that conventional fertilization should be applied based on the analysis about the amount of accumulated nutrient contents in the soil.

Lesch-Nyhan 증후군 환아의 자해에 의한 혀의 외상

김지희,최병재,김성오,최형준,손흥규,이제호 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.3

Lesch-Nyhan 증후군은 드물게 나타나는 X 염색체 열성 유전 질환으로 purine의 대사 장애를 보이는 질환이다. Purine의 대사 장애는 대사에 관여하는 효소인 hypoxanthine guanine phosphoribosyl transferase의 결손 또는 활성 감소로 인하여 나타나며,요산의 과다 생산에 의한 요산과다혈증,요산과다뇨증 등의 신장계 증상과 정신지체,무도증 등의 신경학적 장애를 보이고,구강이나 손가락에 대한 자해를 나타낸다. 이 중 자해 행위는 입술과 혀,손가락을 깨무는 경우가 흔하고,심하면 혀와 손가락이 완전히 절단될 수도 있다. 이 경우 자해로 인한 통증뿐 아니라,연조직 결손으로 인한 심미적인 문제와 상처 부위로의 2차 감염이 발생할 수 있다. 이러한 Lesch-Nyhan 증후군 환자에서 자해를 막기 위해 여러 방법이 사용되고 있는데,이 중 치과적으로 접근하는 방법으로는 마우스 가드나 lip bumper 등의 장치를 이용하는 방법과 해당 치아들을 모두 발거하는 방법,악교정 수술을 통해 개방 교합을 형성해 주는 방법 등이 있다. 본 증례는 13세 9개월의 Lesch-Nyhan 증후군 환아로서 자해에 의해 혀에 심각한 외상을 가한 경우로 마우스 가드를 이용한 보존적인 방법을 사용하였으나 계속적으로 혀에 외상을 가해 하악 전치 뿐 아니라 구치까지 발거하여 치료하였다. Lesch-Nyhan syndrome is a rare X-linked recessively inherited disorder, caused by complete absence or decrease in activity of hypoxanthine guanine phosphoribosyl transferase(HPRT), an enzyme involved in purine metabolism. This enzyme deficiency gives rise to nephropathy symptoms, such as hyperuricosuria and hyperuricemia by excessive uric acid production and neuropathy symptoms, such as mental retardation, choreoathetosis and self mutilation behavior. Patients with Lesch-Nyhan syndrome have tendency to bite their liP, tongue and finger, In severe cases, partial or even total amputation of tongue or finger occur. Self-inflicted bites are often complicated by secondary infection to the injured site as well as pain. Furthermore tissue loss by biting results in esthetic problems. The dental management of self mutilation includes treatment with appliances such as soft mouth guard or lip bumper, extraction of all the teeth, and orthognathic surgery. We report a case of a 13 year-old boy with Lesch-Nyhan syndrome, who severely injured himself on his tongue. At first, conservative treatment using soft mouth guard was considered, but it could not prevent trauma on his tongue. Therefore, extraction of the lower anterior and posterior teeth was carried out.

혈관내피세포-U937세포의 부착에 미치는 Eicosapentaenoic Acid의 효과

김은지,전재은,임현주,차성철,정의룡,조용근,조용근 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1

연구배경: 역학적연구에서 어류의 섭취가 많은 집단에서 관상동맥질환의 빈도가 낮은 것이 보고되었고, 이것은 어류에 많이 함유된 불포화지방산(polyunsaturated fatty acid) 특히 eicosapentaenoic acid 때문으로 생각되어지고 있다. 본 연구에서는 동맥경화증 발생의 초기단계로 여겨지는 단핵구와 혈관내피세포 사이의 adhesion에 미치는 다불포화지방산의 영향을 in vitro system에서 관찰하고자 하였다. 방 법: 제대정맥에서 얻은 혈관내피세포를 배양하여 96 well에 옮기고 25, 50, 100, 200 ㎛ 농도의 eicosapentaenoic acid(EPA)를 6시간 동안 처리한 U937세포를 부착시켜 adhesion assay를 시행하였다. 혈관내피세포를 자극하기 위해서는 lipopolysaccharide(LPS)를 well당 100 ng씩을 투여하였다. 음성대조군으로는 LPS로 자극하지 않은 혈관내피세포에 EPA처리를 하지 않은 U937세포로 adhesion assay한 성적을 사용했고, 양성대조군으로는 LPS로 자극한 혈관내피세포에 EPA처리를 하지 않은 U937세포로 adhesion assay한 성적을 사용했다. 그리고 EPA(3.3 mM)을 5㎛ CuSO4 및 300 ㎛ asscorbic acid와 혼합하여 섭씨 37도에서 16시간 두어 산화-EPA를 만들어 같은 실험을 반복하였다. 결 과: U937세포에 25, 50, 100, 200 ㎛의 EPA로 6시간 처리하였을 때 U937세포의 생존율은 99% 이상이었다. 혈관내피세포를 LPS로 자극했을 때 adhesion assay에서 혈관내피세포에 붙는 U937세포의 수는 현저히 증가하였다. 그러나 EPA를 U937세포에 25, 50, 100, 200 ㎛의 농도로 6시간 처리 후에 lipopolysac-charide를 처리한 제대정맥 내피세포에 부착(adhesion)시켰을 때 처리한 EPA의 각 농도에 따른 부착된 U937세포의 수는 통계적으로 유의한 차이를 나타내지 못했다. EPA처리가 부착된 U937세포의 수에 영향을 미치지 못하였다. 결 론: EPA는 U937세포에 영향을 미쳐 혈관내피세포-U937 세포부착을 감소시키지는 못하였다. 따라서 EPA에 의한 혈관내피세포-단핵구 부착 억제 효과는 EPA의 단핵구에 미치는 영향에 의하지는 않는 것으로 생각되나 추후 더 많은 연구가 필요하리라 생각된다. Background : Epidemiological studies have shown correlation between low incidence of coronary heart disease and high consumption of fish products. It has been suggested that this may be due to the high content of polyunsaturated fatty acids of the n-3 fatty acid group in fish oil. In animal studies eicosapentaenoic and (EPA) inhibited attachment of monocytes to the arterial endothlium. Method : Adhesion assay was performed on the endothelial cells of the human umbilical vein with 25, 50, 100, 200 ㎛ EPA-treated U937 cells. The endothelial cells were activated with lipopoysaccharide (LPS). The adhesion assay was repeated with oxidized EPA. EPA was oxidized with CuSO4 and ascorbic acid. Result : Viability of U937 cells were not afected by concentrations up to 200 ㎛ of EPAand oxidized EPA. LPS treatment of endothelium notably increased the number of U937 cells attached to endothelial cells on the adhesion assay. However, treatment of EPA, native or oxidized, to U937 cells did not afect the number of U937 cells attached to LPS activated endothelial cells. Conclusion : EPA treatment, native or oxidized, of U937 cells did not affect U937 cell-endothlial cell adhesion. This suggests that inhibition of monocyte-endothlial cells ◎attachment by EPA is not due to the effects of EPS on monocytes.(Korean Circulatin J 1998;28(4):606-610)

발견학습을 통한 수학수업의 능률 향상에 관한 연구 : 중1학년 입체도형의 "측정"단원을 중심으로 Focusing on a chapter of "measurement" of a solid figure targeting students in the 1st grade of junior high school

김지영,전재복 국민대학교 2003 기초과학연구소 논문집 Vol.22 No.-

Criticism grows on current mathematics lessons at school lack of mathematical ability and just inclined to the acquirement of fragmentary knowledge and proficiency in solving questions. As a method of enhancing the mathematical ability, discovery learning has been selected and introduced to the class to make the class more interesting and fruitful. Therefore, the objective of this study is to obtain positive effects on school records by raising the interests and concerns of students about mathematics. Through such a research, the study concludes as followings: First, the studying-learning that lays stress on voluntary operations and discovery takes more positive effects on school records than the cramming studying/learning centered on explanation, exercise and memorizing. As a result, the mathematical lesson conducted through the discovery learning is more effective on the improvement of school records by arousing interests of the students. Second, through analyzing answers for the question papers asking the mathematical tendencies, attitudes and interests to both the experimental group and the control group and carried out after applying the discovery learning, it has been proved that the experimental group rather than the control group takes more positive effects on the affective domain. According to the above research, it is revealed that the mathematics lesson adopting the discovery learning shows more positive effects on school records by drawing interests of students in mathematics. Hence it is a task to be solved in the future to develop effective teaching and learning media with regard to mathematics and to make a continuous study on the establishment of mathematics as interesting and effective learning.

매복치의 외과적 노출에 대한 임상적 연구

김지연,김재덕,백종성,손경준 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

Impaction and ectopic eruption of Permanent teeth can cause various clinical Problems. These teeth are not hopeless. It is possible to use the remaining teeth as anchorage, surgically uncover the impacted tooth, and orthodontically move the tooth into the arch. The specific surgical procedure and the orthodontic mechanics, however, will vary depending upon the type of tooth and its position relative to the remaining erupted teeth. There are different surgical techniques for the surgical exposure of the impacted teeth. These case reports described the surgical exposure using the apically positioned flap(APF) and closed eruption technique ,

골수염으로 발현된 재발성 콕시디오이데스 진균증 1예

백지현,박은영,정윤숙,홍재원,채윤태,진성준,최희경,신소연,한상훈,진범식,김창오,최준용,송영구,조남훈,김준명 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.