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      • KCI등재

        한국형 강박장애 치료 알고리듬 2007 (Ⅲ) : 인지행동치료 적용을 위한 예비 조사

        양종철,하태현,김원,김세주,구민성,권준수,김찬형 대한정신약물학회 2007 대한정신약물학회지 Vol.18 No.6

        Objective: The Korean College of Neuropsychopharmacology developed a Korean algorithm for obsessive-compulsive disorder (OCD) to aid clinical decisions. The goal of this preliminary study was to encourage clinical practitioners to treat patients using cognitive-behavioral therapy. Methods: We sent a questionnaire to 34 leading experts on OCD to investigate their opinions about treating patients with OCD using cognitive-behavioral therapy. Results: Of the 34 experts, 12 responded to the survey. The responses indicated that most patients with obsessive-compulsive disorder should be offered cognitive-behavioral therapy, incorporating intensive and sufficient cognitive therapy with response prevention. Conclusion: These results may provide information about the application of cognitive-behavioral therapy to treat obsessive-compulsive disorder. 우리나라에서 시행되고 있는 강박장애 인지행동치료의 국내 실상과 외국에서 제시된 강박장애 인지행동치료 지침들을 종합하여, 강박장애 치료 알고리듬에서 인지행동치료를 어떻게 적용할지를 제안하고자 본 예비 연구를 실시하였으며, 다음과 같은 결론을 얻었다. 첫째, 경한 강박증(mild OCD)의 치료에서는 인지행동치료, 약물치료, 병용치료 모두를 일차치료방법으로 추천하고, 중등도 이상의 심한 강박장애(m oderate or s evere OCD)의 치료에서는 약물치료 또는 병용치료만을 일차치료방법으로 권장한다. 둘째, 강박장애의 치료 시 약물치료와 인지행동치료를 병용하여 치료하는 것이 단독 치료하는 것보다 더 권장된다. 셋째, 강박장애의 인지행동치료는 약 6~10주 동안을, 일주일에 1~2회씩, 한 번의 치료 시 90분 정도로 충분하게 시행함이 권장되는데, 치료 중간에 치료반응이 늦거나 좋지 않다고 판단되면 일주일에 5회 정도까지로 횟수를 늘려서 보다 더 집중적인 치료를 시행할 수 있다. 넷째, 강박장애의 인지행동치료는 노출 및 반응방지(ERP)와 인지치료(CT)가 모두 유용한데, 대체로는 두 가지 기법을 병합하여 치료한다.

      • KCI등재후보
      • KCI등재

        Ziprasidone 사용 후 발생한 호중구감소증

        양종철,김선영,박태원,정영철,정상근,황익근 대한정신약물학회 2007 대한정신약물학회지 Vol.18 No.4

        Neutropenia and agranulocytosis are dangerous conditions seldom caused by antipsychotics. We report the case of a 35-year-old female patient who presented with neutropenia following ziprasidone administration. Ziprasidone was gradually increased to 160 mg/day in combination with escitalopram 10 mg/day. Following ziprasidone administration, her neutrophil count fell to 1700 × 103/mm3 on day 45 and to 1500 × 103/mm3 on day 57. Ziprasidone was immediately stopped, and quetiapine 25 mg was given from the next day onward, along with the escitalopram. Her neutrophil count rose to 2700 × 103/mm3 2 days later, and was maintained at 2900 × 103/mm3 at 17 days after changing medication. To the best of our knowledge, this case represents the first report of ziprasidone-induced neutropenia in Korea. Further study is necessary to determine the incidence of neutropenia and its relationship with agranulocytosis secondary to ziprasidone. 몇 항정신병 약물들은 호중구감소증을 일으킬 위험이 있는 것으로 알려져 왔다. 본 증례에서는 정신분열병의 치료를 위해 ziprasidone을 복용한 후 호중구감소증이 발생되었고, ziprasidone 복약 중단 후 호중구감소증이 회복된 35세 여자 환자를 보고한다. 본 증례에서 나타난 호중구감소증은 ziprasidone의 복용과 관계된 것으로 판단된다. 따라서 ziprasidone의 투약시 호중구감소증의 발생 가능성에 대해서 유의해야 하며, 이에 대한 임상가들의 주지와 체계적인 연구가 필요하다고 본다.

      • KCI등재

        정신치료 지도감독의 의미와 종류

        양종철 대한신경정신의학회 2010 신경정신의학 Vol.49 No.-

        Psychotherapy supervision is one of the most important and specific ways for learning psychoanalytic psychotherapy. In this article, the author describes the meaning, significance, historical background, process, supervisor-supervisee relationship and interaction, boundary issues, and type of psychotherapy supervision.

      • KCI등재

        일반인군과 우울증 환자군에서 한국어판 사회적응 자가평가척도의 심리측정적 특성 평가

        양종철,김재민,신일선,노안영,윤진상 대한신경정신의학회 2003 신경정신의학 Vol.42 No.3

        Objectives:The purpose of this study is to examine the reliability and validity of the Korean version of the Social Adaptation Self-evaluation Scale (KvSASS), and to evaluate its psychometric properties. Methods:KvSASS was administered to two groups, 269 members of the general population and 52 depressive patients, and data on socio-demographic characteristics (age, gender, occupation, marital status, and level of education) and psychological assessment scales (Self-esteem Scale, Beck Depression Inventory, General Health Questionnaire/Quality of Life-12) were collected. For the patient group, data on clinical rating scales and the duration of antidepressant treatment were also obtained. Results:The evaluation of item intercorrelation by the Pearson correlation matrix showed that the number of correlation coefficients over 0.40 was nine. Internal consistency (Cronbach’s alpha), split-half reliability (Guttmans), and test-retest reliability of the KvSASS were good. Three main factors (social activity, self-value oriented activity, and work related activity) were extracted, and three clusters (highly, moderately, and poorly adaptive) emerged by factor and cluster analyses respectively. Concurrent validities with other psychological assessment scales were high. Stepwise multiple regression tests showed that KvSASS was significantly associated with Self-Esteem Scale and General Health Questionnaire/Quality of Life- 12 in the general population group, and with occupation and General Health Questionnaire/Quality of Life-12 in the depressive patient group. Conclusion:KvSASS was a reliable and valid instrument to assess social functioning in both members of general population and depressive patients, and had psychometric properties reflecting the depressive patients’ self-perception of social behavior rather than depressive symptoms themselves

      • KCI등재

        대청도(옹진군)의 관속식물상

        양종철,박수현,하상교,이유미 한국자원식물학회 2012 한국자원식물학회지 Vol.25 No.1

        Distributional surveys for vascular plants were carried out in Daecheong island, Ongjin-gun, South Korea, from 2008 to 2010. The vascular plants recognized from the island were in tatal 402 taxa that were of 90 families, 269 genus, 350species, 3 subspecies, 43 varieties, 6 forms. Among the investigated 402 taxa, 2 Korean endemic plants, 8 rare and endangered plants which was designated by Korea Forest Service, 35 specially plants designated by the Ministry of Environment were included. The naturalized plants were identified as 40 taxa and the percentage of naturalized plants index was 9.9%. In addition, an unrecorded species, Thyrocarpus glochidiatus Maxim (Boraginaceae), was recognized from the island. 본 연구는 2008년과 2010년에 걸쳐 3차례 식물상을 조사하였으며, 전체 조사된 분류군은 90과 269속 351종 3아종 43변종 6품종등 403분류군이 확인되었다. 주요 식물들로 특산식물이 서울제비꽃 등 2분류군이 확인되었고, 산림청지정 희귀 및 멸종위기 식물이 대청부채(CR) 등 8분류군, 환경부 지정 특정식물은 금방망이(Ⅴ) 등 35분류군으로 나타났다. 또한 식물지리학적 분포특성에 있어 남방계식물과 북방계식물이 함께 확인되었다. 귀화식물은 대청가시풀 등 40분류군이 확인되었으며, 한반도 미기록종인 대청지치가 새로이 발견되었다.

      • KCI등재

        Mirtazepine 사용에 의한 지속성 딸꾹질의 치료

        양종철 대한정신약물학회 2008 대한정신약물학회지 Vol.19 No.1

        Hiccups are defined as involuntary contractions of the diaphragm and intercostal muscles. Most instances of hiccups are self-limiting, but intractable hiccups can sometimes lead to multiple problems including exhaustion. A 56-year-old female visited our psychiatric department due to persistent hiccups and insomnia. Initially, she was unsuccessfully managed using conservative methods, i.e., holding her breath, drinking water, inducing a gag reflex, and orally administering haloperidol. We administered Remeron Soltab, and the hiccups disappeared. We conclude that mirtazapine is a useful treatment for persistent hiccups. ‘지속성 딸꾹질’의 발생 기전은 명확하지 않지만 다양한 기저질환과의 관련성이 제시되었으며, 경험적인 효과에 근거한 다양한 치료 방법들이 보고되었다. 본 증례에서는‘지속성 딸꾹질’을 보인 56세 여자 환자에게 mir-tazepine을 투여하여 치료한 사례를 보고하였다. 이는 mirtazepine이‘지속성 딸꾹질’에 대한 치료 방법의 하나로 사용될 수 있음을 시사한다. 이에 대한 기전을 밝히기 위해서는 향후 더 체계적인 연구들이 필요하다고 본다.

      • KCI등재

        한국형 공황장애 약물치료 알고리듬 2008:초기치료전략

        양종철,김민숙,유범희,윤세창,이상혁,서호석,김찬형 대한정신약물학회 2009 대한정신약물학회지 Vol.20 No.1

        Objective:The Korean Association of Anxiety Disorders developed a Korean treatment algorithm for panic disorder to help clinicians make treatment decisions. This study investigated a consensus about initial treatment strategies as part of developing a medication algorithm for panic disorders in Korea. Methods Based on current treatment algorithms published by the American Psychiatric Association, the National Institute for Clinical Excellence, and the Canadian Psychiatric Association, we developed questionnaires about initial treatment strategies for patients with panic disorder. Fifty-four experts in panic disorder answered the questionnaires. We classified expert opinions into three categories (first-, second-, and third-line treatment strategies) by χ2 tests. Results:Antidepressants and anxiolytics were recommended as first-line strategies for the initial treatment of panic disorder. A combination of medical treatment and cognitive-behavioral therapy was also recommended for more severe cases. Paroxetine, escitalopram, alprazolam, and clonazepam were preferred from among many anti-panic drugs. The mean starting dose of anti-panic drugs in the initial treatment for panic disorder was relatively lower than that for such other psychiatric illnesses as major depressive disorder. Conclusion:These results, reflecting recent studies and clinical experiences, may provide guidelines about initial treatment strategies for panic disorder.

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