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      • Characterization of cricket song patterns and the behavior observation of Teleogryllus emma (Orthoptera:Grylloidea)

        Ji Chang Woo,Kim Nam-Jung,Lee Sang-Guei,Hwang-Yong Kim,Choi Hoon-Sik,Song In-Sun,Ko Jee Sun 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05

        We analyzed the chirp sound and behavior of Teleogryllus emma with observation system, which was consisted of computer, ccd-camera and microphone. Computational methods of wavelet transformation and Self-Organizing Maps (SOM) were utilized to characterized the chirp sound of insect species for automatic counting in this study. Wavelets were initially applied to feature extraction of the chirp sound. Wavelet coefficients were accordingly calculated based on the basis function (e.g., Morlet). The obtained coefficients were subsequently provided to count number of chirps in each song. Sound structure of insect specimens consisted with long chirp and short chirp and the patterns of song were grouped by frequency of long chirp and short chirp. The song patterns of insect specimens were divided by Self-Organizing Map (SOM) that was used number of chirp as input data. Application of computational methods to automatic detection of chirp sound was further discussed for obtaining objective assessment in behavior science.

      • KCI등재후보

        진피내에 발생한 신경초종 3례

        송준영,박의수,김석주,노용지 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.3

        A neurilemmoma is a relatively uncommon tumor of the nerve sheath and almost never in malignant form. It is a slow-growing, encapsulated nerve tumor. Benign neurilemmoma occur commonly in the cranial acoustic nerves, but can occur on the flexor surfaces of the upper and lower limbs. There is no appreciable sex predilection, and most cases are seen in adults past the age of 30 years. The tumor has been seen to arise in major nerves and nerve branches, including the posterior tibial nerve, peroneal nerve, and femoral nerve. Common differential diagnoses are ganglion, lipoma, neuroma, and hemangioma. Symptoms most often are a palpable mass, usually tender to palpatioin. A history of a localized area of swelling that increases in size and firmness over a period of several years is usual. Hitsologically, the tumor is composed of antoni type A and B tissue. In Antoni type A tissue, there are interlacing bundles of spindle-shaped cells arranged in a compact fashion with a pallisading of cell uunuclei. Antoni type B tissue exhibits the same type of cells loosely arranged with intervening collagen fibers. The tumor usually is located in deep tissue and rarely is just under the epidermis. And so we represents 3 cases of intradermal neurilemmoma in our department of dermatology.

      • 저자계측정을 위한 종형 Hall 소자의 교류구동 원리

        송명희,김정헌,박용우,류지구 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        In this paper, the vertical Hall device which is sensitive to the magnetic fields parallel to the surface of the chip, is fabricated and characterized. The Hall voltage was ±0.2[mV] in the range of ±100[Gauss]. The current-related Magnetic sensitivity(S_(H)) was about 55[V/AT]. With an increased I_(sup), the offset voltage was also increased. Alternating Current(AC) driving system was used to process the amplification of Hall voltage and the reduction of offset and noise by the AC driving of the vertical Hall device. When the AC driving system was operated, the output of the Hall voltage was ±74.0 [mV] in the low magnetic field ranges of ±100 [Gauss], The magnetic fields resolution was 0.74[mV/Gauss].

      • 白鼠胎仔 골격발생과정에 미치는 Chlorambucil과 Tocopherol의 相互作用에 關한 實驗的 硏究

        宋志南,全容赫 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.3

        The effect of tocopherol to the teratogenecity due to chlorambucil have been studied on the developing skeleton in prenatal offsprings from 27 mothers of albino rat through macroscopic and microscopic observations. 1. None of the significant abnormality has been observed on either macroscopic or microscopic features in the fetal group treated with single dose of tocopherol administration the mother, except, the group treated with continuous 3 doses of it to the mother, of which the measures of the weight and stature of them are generally decreased than those of the normal contrast. 2. Though the degree of teratogenecity on the developing fetal skeletal frame due to the chlorambucil is mainly depend upon the amount of the drug and the time of administration during pregnancy of mother, the highest to teratogenetic effect could be elicitable on the fetuses at the day 12th, while, none of significant effect could be detectable in the fetuses after the time of day 14th of pregnancy on the administration of the chlorambucil. 3. The protective effectiveness of the tocopherol from the teratogenecity on the fetal skeletogenesis due to the chlorambucil appears not to be efficient. On the contrary, the concomitant use of tocopheral with chlorarmbucil tends to be facilitate the teratogenetic effect of the chlorambucil, furthermore, the rate is higher against with increase of the date of pregnancy.

      • KCI등재

        병식 평가 척도-한국판(SUMD-K)의 신뢰도와 타당도 검증

        송지영,김기태,이서경,김용희,노준호,김종우,장환일,반건호,강원섭 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

        Objectives : This study was conducted to evaluate the reliability and the validity of the Korean version of the Scale to Assessment Unawareness of Mental Disorder (SUMD-K). Methods : The subjects were 55 schizophrenic patients between ages of 26 and 58 who were recruited from the psychiatric unit of the university hospital and the out-patient clinic. The SUMD-K and insight scale of PANSS were applied to the patients. Results : The range of inter-rater (Spearman's rho) of the general items of SUMD-K were .97-.98 on the current illness and .58-.98 on the past illness. The correlation coefficient between the sum and the general items of the SUMD-K showed high scores. The concurrent validity between SUMD-K and insight item of PANSS was high (scores between .59-.96). However,the reliability and the validity of the attribution items of symptoms showed low scores compared to the current symptoms. Conclusion : The SUMD-K was confirmed in its reliability and validity. It can be a useful clinician-rating scale for evaluating insight in schizophrenic patients as well as patients with other neuropsychiatric conditions.

      • VRSA에 대한 항생물질을 생산하는 방선균의 분리

        이지연,양시용,고은지,이승구,김시관,조왕식,송민동 建國大學校 自然科學硏究所 2002 建國自然科學硏究誌 Vol.13 No.2

        본 연구가 VRSA에 대한 신규 항생물질 생산 균주를 얻기 위하여 실시하였다. 국내외에 채취한 토양시료에서 분리한 방선균 중, 임상분리 VRSA와 돌연변이 유발 VRSA에 대해 항균성을 나타내는 JY-24를 선별하였다. 선발 균주는 원통형의 포자 모양을 갖고 있으며, Bennett's 배지에 배양시 aerial mycelium color는 흰색을 나타냈으며, reverse side color는 대체로 노란색을 나타내었다. 항균물질 생산을 위한 탄소원으로는 fructose, mannose, 질소원으로는 yeast extract가 가장 우수하였으며 glucose의 첨가로 항균 물질 생산성이 증가하는 것으로 나타났다. 최적 초기 pH는 pH 7로 나타났으며, 28 ℃, 37℃, 45 ℃의 온도에서 균이 성장하는 것으로 나타났다. 또한 배양기간에 따라 항균물질 생산성을 조사한 결과, 임상분리 균주에 대해 5일 배양 시 가장 높았으나, 3일 배양과 7일 배양 시 동일한 생산성을 나타내 생산속도가 빠르며, 안정한 물질인 것이 파악되었다. 향후 균주동정 및 항균물질 정제에 관한 연구를 수행하고자 한다. An antibiotic substance producing strain JY-24, effective to the VRSA (Vancomycin-resistant Staphylococcus aureus), was isolated from soil. The spore chain of JY-24 was cylindrical, and its sulface was smooth. The aerial mass color of the strain was white, and its reverse side color was yellow. The strain did not produce soluble pigment. For the production antibiotics, fructose, mannose and yeast extract were favorable as carbon and nitrogen sources. Optimal initial pH for the production of the antibiotic was pH 7. Accumulation of the antibiotic in the culture broth reached at maximal level after 5 days cultivation in Bennett's medium.

      • 항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

        남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        Polyozellus multiplex가 생산하는 지질과산화 저해물질

        황지숙,송경식,김양섭,석순자,이태호,유익동 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.5

        담자균류로부터 지질과산화 저해물질을 탐색하던 중 강원도 오대산 지역에 자생하는 버섯의 한 종류로 부터, Sparague-Dawley계 rat의 간 mirosome 분획의 지질과산화를 강하게 억제하는 물질이 있음을 발견하였다. 이 버섯의 미생물학적 특성을 관찰한 결과 민주름버섯목, 굴뚝버섯과에 속하는 까치버섯(Polyzellus multiplex)으로 동정하였으며 본 버섯의 자실체 methanol 추출물을 benzene, ethylacetate로 순차적으로 추출하고 각종 chromatography를 이용하여 활성물질을 정제한 결과, ethylacetate층으로 부터 황산화활성을 나타내는 PM1을 benzene층으로 부터 지방산 계열의 PM2와 PM3 화합물을 순수하게 분리 정제하였다. PM1은 정색반응 및 각종 기기분석 결과 thelephoric acid계의 화합물로 동정되었으며 PM2 및 PM3는 각각 linoleic acid와 oleic acid로 동정되었다. 지질과산화 활성물질로 분리정제한 PM1 화합물의 IC_50 값은 1.96 ppm이었으며 LD_50 값은 500 mg/Kg 이상이었다. In the course of screening lipid peroxidation inhibitor from basidiomycetes, a mushroom, which was collected at O-Dae mountain in Kangweon-Do, was found to have active compound. The mushroom was identified as Polyzellus multiplex, which belongs to Aphylloporalles Thelephoraceae, on the basis of macroscopic and microscopic characteristics of the fruiting body. The methanol extract of fruiting body was extracted with benzene and ethylacetate, sequentially. By using various kinds of chromatographies, PM1, and PM2 and PM3, were purified from the ethylacetate extract and the benzene extract, respectively. Color reaction and analyses of IR, UV, and NMR spectra indicated that PM1 was a derivative of thelephoric acid, and PM2 and PM3 were linoleic acid and oleic acid, respectively. IC_50 of PM1 for inhibition of lipid peroxidation was 1.96 ppm and LD_50 was 500 mg/kg.

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