제주 성상 S/S MTr #1 행원 풍력단지 전압해석

김상준(Sang-Jun Kim),조민호(Min-Ho Cho),윤기갑(Gi-Gab Yoon),장상옥(Sang-Ok Jang),안정식(Jeong-Shik Ahn) 대한전기학회 2003 대한전기학회 학술대회 논문집 Vol.2003 No.11

Breast Cancer Screening by Clinical Examination and Mammography in Korea

Sung Soo Kang(강성수),Byung Jun Park(박병준),Soon Gi Hong(홍순기),Sun Duk Kim(김순덕),Kyung Sang Lee(이경상),Jee Hyun Lee(이지현),Sung Kong Lee(이성공),Sei Ok Yoon(윤세옥) 대한여성건강학회 2000 여성건강 Vol.1 No.2

The novel method for determining the accuracy of intra-articular injection in the laboratory animals

Sang Hee Lee,Min Seong Jang,Kyung-su Cha,Jung-hui Jang,Chul Kyun Kim,Young Kil Kim,Eun-Jung Bae,Ok-Lan Yoon,Kang-Hyun Han,Jung-Ho Noh,Yong-Bum Kim 한국실험동물학회 2018 한국실험동물학회 학술발표대회 논문집 Vol.2018 No.7

Differential effects of treadmill exercise on cyclooxygenase-2 in the rat hippocampus at early and chronic stages of diabetes

Sung Min Nam,Sun Shin Yi,Ki-Yeon Yoo,Ok Kyu Park,Bingchun Yan,Wook Song,Moo-Ho Won,Yeo Sung Yoon,Je Kyung Seong 한국실험동물학회 2011 Laboratory Animal Research Vol.27 No.3

Cyclooxygenase-2 (COX-2) is believed to be a multifunctional neural modulator that affects synaptic plasticity in the hippocampus. In the present study, we investigated the differential effects of treadmill exercise on COX-2 immunoreactivity in the dentate gyrus in early and chronic diabetic stages in Zucker diabetic fatty (ZDF) rats and lean control (ZLC) rats. To this end, ZLC and ZDF rats at 6 or 23 weeks of age were put on a treadmill with or without running for 1 h/day for 5 consecutive days at 16-22 m/min for 5 weeks or 12-16 m/min for 7 weeks, respectively. Treadmill exercise in prediabetic and chronic diabetic rats significantly reduced blood glucose levels. In particular, exercise in the prediabetic rat blocked the onset of diabetes. COX-2 immunoreactivity was mainly detected in the granule cell layer of the dentate gyrus and stratum pyramidale of the CA3 region in all groups. COX-2 immunoreactivity was significantly increased in these regions of ZLC and ZDF rats after treadmill exercise in the early diabetic stage. However, COX-2 immunoreactivity was not changed in these regions in ZDF rats after treadmill exercise in the chronic stage. These results suggest that treadmill exercise in diabetic animals in the chronic stage has limited ability to cause plasticity in the dentate gyrus.

Effects of Low-Intensity Combined Exercise Program on Body Composition and Functional Fitness in Elderly Women

( Yoon Ho Jang ),( Yoon Sik Kim ),( Sung Wook Chun ),( Ye Ju Lee ),( Mi Ok Kim ),( Eur Soon Kim ),( Byeoung Gu Kim ),( Sang Keun Shin ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1

Purpose: This research aimed to verify the effects of a 32-week low-intensity combined exercise program as an exercise intervention on body composition and functional fitness in elderly women. Method: A total of 24 subjects were assigned to Otago exercise group(n=12) and control group(n=12) randomly. A 60 minute Otago exercise was applied to them as the intervention 3 times a week for 32 weeks by 20-25%HRR. Exercise Intensity was set by using Polar and %HRR, with participants’ heart rates monitored. Body composition was measured and calculated to compare the effects of exercise on the baseline and 32 weeks later. Items for body composition contained height, weight, BMI, WHR, %fat, %LBM, Fat, LBM, fat/height, and LBM/height. Functional fitness was measured by Senior Fitness Test. Mean and standard deviations were calculated to analyze the research data by using SPSS Version 22.0. A two-way repeated measures ANOVA was conducted to verify interactions between pre-post measurement and groups. Statistical significance was set at p<.05. Result: This research showed that no significant interactions between pre-post measurement and groups appeared in any body composition items for Otago exercise group. It showed a significant increase(p<.05) between pre-post measurements in WHR for Otago exercise group and between groups. There were significant interactions between time and groups in 30-second chair stand(p<.01), 30-second arm curl(p<.05), back scratch(p<.01) and 8-foot up-and-go(p<.05) for Otago exercise group. Significant increase appeared between groups in 30-second chair stand(p<.01), and 30-second arm curl(p<.001) for Otago exercise group. Significant increase appeared between time in 30-second chair stand(p<.05), and back scratch(p<.05) for Otago exercise group. Conclusion: Although 32-week low-intensity combined exercise had no effects on body composition in elderly women, it verified the significant decrease between pre-post measurements of WHR for exercise group. And this exercise program showed the effects on low body strength, upper body strength, upper body flexibility, dynamic balance and agility for exercise group in elderly women. In spite of low-intensity exercise by 20-25%HRR, this program can be used as an effective and safe exercise intervention to improve strength and prevent falls for elderly women living in a community.

Partial Amino-Terminal Signal Sequence of Bovine Gastric Prepepsinogen

Yoon, Joo-Ok,Yoon, Sang-Kee 동국대학교 재료과학연구소 1983 材料科學硏究所 論文集 Vol.3 No.-

소의 제 4 위점막에서 얻은 RNA를 밀 배아 무세포 단백질 합성계에서 번역한 결과, 주 번역산물은 그 면역침전물에 대한 SDS-폴리아크릴아미드 젤 전기영동과, 아미노-말단부의 아미노산 배열 결정으로 프리펩시노젠임이 확인되었다. 즉 번역단백질은 펩시노젠의 아미노-말단에 다시 16 잔기로 된 시그날 펩티드를 달고 있었다. 이 시그날 펩티드의 구조는 다음과 같았다. Met-X-X-Met-Val-Val-X-Val-Val-X-Leu-X-Leu-Leu-X-X-펩시노젠. The major translation product of bovine fourth stomach mucosa RNA in a wheat germ cell-free system was identified as prepepsinogen by electrophoretic analysis of its immunoprecipitate on sodium dodecyl sulfate-polyacrylamide gels and amino-terminal sequence determination. The translation product had an aminoterminal extension peptide comprising 16 amino acid residues. A partial amino acid sequence of this extension peptide was as follows: Met-X-X-Met-Val-Val-X-Val-Val-X-Leu-X-Leu-Leu-X-X-pepsinogen.

Validation of QF-PCR for Rapid Prenatal Diagnosis of Common Chromosomal Aneuploidies in Korea

Sung-Hee Han,Jae-Song Ryu,Jeong-Wook An,Ok-Kyoung Park,Hye-Ryoung Yoon,Young-Ho Yang,Kyoung-Ryul Lee 대한의학유전학회 2010 대한의학유전학회지 Vol.7 No.1

목적 : QF-PCR법은 흔한 염색체 이수성에 대한 빠른 산전 진단을 가능하게 하는데, 낮은 가격, 빠른 속도, 그리고 자동화가 가능하여 한꺼번에 많은 검체에 대해 적용할 수 있다는 장점들이 있다. 하지만 아직까지 국내에서 QF-PCR법은 산전 염색체 이수성 선별검사로 주로 사용되는 방법이 아니다. 본 연구에서는 한국인에서 빠른 산전 진단을 목적으로 시행하는 짧은 염기서열 반복(short tandem repeats, STR) 표지자를 이용한 QF-PCR법의 수행능을 검증하고자 한다. 대상 및 방법 : 2007년에서 2009년까지 산전 염색체 이수성 선별을 목적으로 의뢰된 847개의 양수 검체에 대해 QF-PCR법을 시행하였는데 13번, 18번, 21번, X, Y염색체에 위치한 총 20개의 STR 표지자로 구성된 Elucigene kit (Gen-Probe, Abingdon, UK)를 사용하였다. 총 847개의 양수 검체에 대한QF-PCR 결과는 염색체 검사 결과와 비교하였고, STR 표지자의 정보력을 평가하기 위해서 각 표지자에 대해 이형접합체 지수(heterozygosity index)를 구하였다. 결과 : 총 847개 양수 검체에 대한 QF-PCR 검사 결과 19개(2.2%, 19/847)에서 13, 18, 21번 염색체와 X, Y염색체의 수적 이상이 관찰되었는데 염색체 검사에서도 동일한 결과를 보여100% 양성 예측율을 나타냈다. 하지만 염색체 검사 결과 7개(0.8%, 7/847) 검체에서 5개의 균형전좌와 2개의 불균형 염색체 이상이 관찰되었으나 QF-PCR에서는 진단되지 않았다. STR 표지자의 평균 이형접합체 지수(he-terozygosity index)는 0.76으로 서양인에서 보고된 0.8에 비해 다소 낮았다. 본 연구에서 D13S634표지자의 미세수준의 중복(submicroscopic duplication)이 1.4% (12/847)에서 관찰되었는데 이는 한국인에서 특징적인 소견으로 생각된다. 결론 : 본 기관에서는 산전 염색체 이수성 선별을 위한 QF-PCR법을 검증하였으며 효율적이고 신뢰할 수 있는 방법임이 입증되었다. 하지만 QF-PCR결과를 해석하기 위한 지침을 만들기 위해서 검사실마다 독립적으로 각각의 STR표지자에 대한 검증이 필요하며, 또한 QF-PCR법을 통상적인 염색체 검사 업무흐름에 통합하는 것이 필요하다고 사료된다. Purpose: Quantitative fluorescent polymerase chain reaction (QF-PCR) allows for the rapid prenatal diagnosis of common aneuploidies. The main advantages of this assay are its low cost, speed, and automation, allowing for large-scale application. However, despite these advantages, it is not a routine method for prenatal aneuploidy screening in Korea. Our objective in the present study was to validate the performance of QF-PCR using short tandem repeat (STR) markers in a Korean population as a means for rapid prenatal diagnosis. Material and Methods: A QF-PCR assay using an Elucigene kit (Gen-Probe, Abingdon, UK), containing 20 STR markers located on chromosomes 13, 18, 21, X and Y, was performed on 847 amniotic fluid (AF) samples for prenatal aneuploidy screening referred for prenatal aneuploidy screening from 2007 to 2009. The results were then compared to those obtained using conventional cytogenetic analysis. To evaluate the informativity of STR markers, the heterozygosity index of each marker was determined in all the samples. Results: Three autosomes (13, 18, and 21) and X and Y chromosome aneuploidies were detected in 19 cases (2.2%, 19/847) after QF-PCR analysis of the 847 AF samples. Their results are identical to those of conventional cytogenetic analysis, with 100% positive predictive value. However, after cytogenetic analysis, 7 cases (0.8%, 7/847) were found to have 5 balanced and 2 unbalanced chromosomal abnormalities that were not detected by QF-PCR. The STR markers had a slightly low heterozygosity index (average: 0.76) compared to those reported in Caucasians (average: 0.80). Submicroscopic duplication of D13S634 marker, which might be a unique finding in Koreans, was detected in 1.4% (12/847) of the samples in the present study. Conclusion: A QF-PCR assay for prenatal aneuploidy screening was validated in our institution and proved to be efficient and reliable. However, we suggest that each laboratory must perform an independent validation test for each STR marker in order to develop interpretation guidelines of the results and must integrate QF-PCR into the routine cytogenetic laboratory workflow.

Improve of Efficiency in Silicon Thin-Film Solar Cells by Optimizing Front TCO and Back Reflector

Sang Won Jeon,Jeong Chul Lee,Sae Jin Ahn,Jae Ho Yun,Seok Ki Kim,Jinsoo Song,Byung Ok Park,Kyung Hoon Yoon 한국진공학회 2005 한국진공학회 학술발표회초록집 Vol.- No.-

Microwave dielectric properties of glass-Bi₂Ti₂O7 ceramic composites

Sang Ok Yoon,Kwan Soo Kim,Sang Heung Shim,Yun Han Kim,Shin Kim 한양대학교 세라믹연구소 2008 Journal of Ceramic Processing Research Vol.9 No.1

The microwave dielectric properties of glass-Bi₂Ti₂O7 ceramic composites were investigated. Using bismuth-zinc borosilicate (BZBS) glass and TiO₂, glass-Bi₂Ti₂O7 composites were prepared by liquid phase sintering. The linear shrinkage exhibited a two-stage sintering behavior; viscous flow of the liquid phase and then crystallization. The crystalline phases of Bi₂Ti₄O₁₁and Bi₂Ti₂O7 were observed at 700 and 900oC, respectively. The dielectric constant (εr) and the quality factor (Q×f0) were affected by the formation of crystalline phases as well as the density. For the specimen sintered at 900oC, the dielectric constant, the quality factor and the temperature coefficient of the resonant frequency (τf) was respectively 56.4, 518 GHz (105 at 4.898 GHz), and +119 ppm/K. The microwave dielectric properties of glass-Bi₂Ti₂O7 ceramic composites were investigated. Using bismuth-zinc borosilicate (BZBS) glass and TiO₂, glass-Bi₂Ti₂O7 composites were prepared by liquid phase sintering. The linear shrinkage exhibited a two-stage sintering behavior; viscous flow of the liquid phase and then crystallization. The crystalline phases of Bi₂Ti₄O₁₁and Bi₂Ti₂O7 were observed at 700 and 900oC, respectively. The dielectric constant (εr) and the quality factor (Q×f0) were affected by the formation of crystalline phases as well as the density. For the specimen sintered at 900oC, the dielectric constant, the quality factor and the temperature coefficient of the resonant frequency (τf) was respectively 56.4, 518 GHz (105 at 4.898 GHz), and +119 ppm/K.

Evaluation of Cardiovascular Health Promotion Programs Offered to Mid-life Women in Korea

Ok Kyung Ham,Mi Hyoung Lee,Sang Yeon Park,Dong Soo Shin,Yoon Jung Chun 한국간호과학회 2007 한국간호과학회 학술대회 Vol.2007 No.11