Time-Related Changes in Detrusor Overactivity in Awake Rats with Spinal Cord Injury Observed by Simultaneous Registrations of Intravesical and Intraabdominal Pressures

Jin, Long-Hu,Shin, Hwa-Yoan,Yoon, Seung-Hwan,Seong, Do-Hwan,Park, Chang-Shin,Lee, Tack,Yoon, Sang-Min Korean Continence Society 2011 International Neurourology Journal Vol.15 No.1

<P><B>Purpose</B></P><P>To compare the physical characteristics of detrusor overactivity (DO) induced by intravesical infusion of saline in awake, sham rats and rats with chronic spinal cord injury (SCI), by simultaneous registrations of intravesical and intraabdominal pressures.</P><P><B>Methods</B></P><P>Male Sprague-Dawley rats, normal or with a spinal vascular clip at the level of Th9, were investigated cystometrically 1 and 4 weeks after SCI. Intravesical pressure (IVP) and intraabdominal pressure (IAP) were recorded simultaneously to evaluate true DO. During the filling phase, the event of IVP rises, defined as increments that exceeded 2 cmH<SUB>2</SUB>O from baseline, were determined as DO according to the absence of simultaneous changes in IAP.</P><P><B>Results</B></P><P>All SCI rats exhibited DO during the filling phase, which was not shown in sham rats. The frequency and pressure of DO had a tendency to decrease with time. The DO frequency of SCI rats after 4 weeks (0.9±0.2 min<SUP>-1</SUP>) was decreased compared with that after 1 week (2.1±0.4 min<SUP>-1</SUP>; P<0.05). The DO pressure of SCI rats after 4 weeks (8.4±1.9 cmH<SUB>2</SUB>O) was decreased compared with that after 1 week (11.6±2.9 cmH<SUB>2</SUB>O; P>0.05).</P><P><B>Conclusions</B></P><P>Cystometric studies in awake male SCI rats showed some significant changes in bladder function after SCI. All SCI rats exhibited DO during the filling phase, and showed different physical characteristics of DO over the course of time. The neurological basis of these time-related changes remains poorly understood, but may provide important prognostic information about long-term urological management in SCI patients.</P>

하악전돌증의 악교정수술 후 연조직 형태변화에 대한 연구

성상진,박현도,김재승,문윤식 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.3

악교정수술에 관한 치료계획은 치료결과에 관한 정확한 예측을 바탕으로 수립되는 것이 바람직하며 이는 심미적인 결과를 얻기 위한 가장 중요한 요소 중에 하나이다. 성인에서 골격성 하악전돌증의 치료는 하악골후퇴술을 이용한 악교정수술법이 주로 이용되는데, 술후 턱끝의 돌출도가 과도하게 감소되어 하악전진이부성형술을 추가로 시행해야 하는 경우 하악골과 턱 부위의 연조직 변화방향이 상이하게 나타나므로 술후 연조직 변화를 정확히 예측하는데 한계가 있다. 본 연구에서는 골격성 하악전돌증을 주소로 악교정수술을 시행한 성인을 대상으로, 상행지시상분할골절단술(BSSRO)만을 시행한 경우(A군) 11명과 하악전진이부성형술(advancement genioplasty)도 같이 시행한 경우(B군) 9명의 경조직과 연조직 변화의 상관관계를 알아보기 위하여, 수술 8개월 이후에 채득된 측모두부계측방사선사진을 비교하여 다음과 같은 결과를 얻었다. 1. E-line에 대하여 상순은 더 돌출되고 하순은 더 후퇴되어 입술의 형태가 개선되었으며,하악전진이부성형술을 병행한 경우 하순의 돌출도는 더 개선되었다. 2. 두 군 모두에서 상순은 후방이동하고 비순각은 증가하였다. 3. 술후 B점에 대한 연조직 POGs점의 변화율은 A군에서 84%, B군에서 66%로 나타났으며 두 군간에 통계적 유의성이 있었다. 4. 경조직과 계측점의 수직변화량은 A군에서 감소하였다. The treatment plan for orthognathic surgery must be based on accurate predictions, and this can be produced the most esthetic results. Treatment of prognathic mandible in adult is usually orthognathic surgery using mandible set back, but mandible with retruded chin point is needed additional chin augmentation. In this case, the directions between mandible and chin point are different therefore, the prediction of soft tissue reactions must be modified. In this study, we materialize the patients who was taken orthognathic surgery due to prognathic mandible, 11each(Group A) was taken only Bilateral Sagittal Sprit Ramus Osteotomy (BSSRO), 9each(Group B) was taken additional advancement genioplasty. The lateral cephalometric radiography taken 8 months later after orthognathic surgery by this patients were used. The results of this study were as follows : 1.The profile of lips was favorable after surgery due to upper lip to E-line became prominent and lower lip to E-line was retruded. 2.In both group, upper lip moved posteriorly and nasolabial angle was increased. 3.The ratio of the soft tissue profile change in POGs point to skeletal B point movement was 84% in group A and 66% in group B, and there was statistical significance between group A and group B. 4.Vertical movement of hard tissue points is decreased in group A.

후두 및 하인두 편평세포암종에서 E-cadherin의 면역조직화학적 발현

도남용,나한조,이도용,허준,최지윤,이홍영,임성철 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Background and Objectives : The cell-cell adhesion molecule E-cadherin is necessary for the maintenance of the epithelial cellular structure. We were designed to confirm the significance of E-cadherin as a marker for differentiation and invasiveness of squamous cell carcinoma of the larynx and hypopharynx. Materials and Methods : Our study was investigated for the immunohistochemical expression of the epithelium-specific cell adhesion molecule E-cadherin in formalin fixed paraffin embedded tissue specimen of 32 cases of squamous cell carcinoma of larynx and hypopharynx. Results : The positive expression of E-cadherin was 56.3%(18 cases) in squamous cell carcinoma of the larynx and hypopharynx. Decreased E-cadherin expression was a stastistically significant correlation with a increased grade of lymph node stage and clinical stage. Reduced expression was seen in the large tumor size and poorly differentiated tumors, but these result was not statistically significant. Conclusion : The expression of E-cadherin may be related with progression of squamous cell carcinoma of the larynx and hypopharynx. But these correlation were not sufficient for the prognostic indicators in squamous cell carcinomas of the larynx and hypopharynx.

Shield Disk 상의 Ag-Cu 공정계 합금 도금기술 개발

윤경도,차동관,심기종,민봉기,최순돈,이상기 嶺南大學校 工業技術硏究所 2003 工業技術硏究所論文集 Vol.31 No.1

The composition and the microstructure of the Ag-Cu alloy electrodeposits electroplated in Succinimide bath were investigated varying the electrolysis conditions such as bath composition, current density and additive agents etc. The cathode overpotential increased with the increase of Succinimide concentration and current density ratio in the bath. The Ag content of the alloy deposits decreased with the increase of current density and pH and temperature in the bath. The optimum condition for 78wt.%Ag-22wt.%Cu code position alloy is an follows : pH10(adjusted by NH_4OH), 0.03M AgNO_3, 0.27M Cu(NO_3)_2 3H_2O, 0.5M Succinimide in bath and 3.5A/dm^2∼5.5A/dm^2 current density.

스쿠버다이빙 참가유형에 따른 라이프스타일에 관한 연구

윤상문,최정도 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.2

The purpose of this study was to investigate opportunities in the scuba diving market and examine the lifestyles of scuba diving customers based on the pattern of their participation in scuba diving in order to provide the important data for developing effective marketing strategies. The subjects included 843 scuba diving customers of scuba diving resorts or scuba diving pro shops in the Republic of Korea. They were asked to complete a survey at either a resort or a pro shop. The statistical analyses were performed by using the SPSS 10.0 software. The statistical techniques used for analysis were factor analysis, reliability analysis, frequency. One-way ANOVA, and Scheffe's post hoc test. Statistical significance was accepted at an alpha level of p<.05. The major findings of this study were as follows: First, individuals pursuing for health showed the highest participation in scuba diving at four times or more a week. It was followed by innovators who were very receptive to new ideas, individuals valuing social recognition, and individuals who were followers of fashion and trends. Second, individuals with less than 3 years of scuba diving experience were most often found among the followers, and followed by conservative people. Individuals with at least 11 years of scuba diving experience were most often found among the innovators, and followed by the individuals valuing social recognition. Third, individuals with advanced scuba diving skills were most often found among the individuals pursuing for health. It was followed by the innovators, and the individuals valuing social recognition. In the meantime, the beginners were most often found among the followers and the conservative people. Fourth, all different lifestyle groups showed significantly differences when they participated in scuba diving with their colleagues, friends or alumni. The individuals pursuing for health showed the highest difference and were followed by the innovators, the individuals valuing social recognition, the followers, and the conservative people. Fifth, the conservative group showed significantly higher interest in improving health and fitness as a reason to participate in scuba diving. The individuals valuing social recognition showed significantly higher interest in learning scuba diving skills, the followers participated in for social reasons, and the individuals pursuing for health and the innovators wanted to have a scuba diving career.

Kodak Insight 구내필름의 치아우식증 진단능에 대한 연구

윤영남,이상래,이병도 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1

Purpose : To compare the diagnostic accuracy of Kodak Insight film with other intra-oral films in the detection of dental caries. Materials and Methods : Periapical radiographs of 99 extracted human teeth with sound proximal surfaces and interproximal artificial cavities were made on Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Kodak Insight films and automatically processed. Six dentists examined the presence of dental caries using a five-point confidence rating scale and compared the diagnostic accuracy by ROC (Receiver Operating Characteristic) analysis and ANOVA test. Results : The sensitivity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.84, 0.77, 0.75 and 0.79 respectively. The specificity of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.97, 0.95, 0.96 and 0.94 respectively. The mean ROC areas (Az) of Kodak Ultra speed, Ektaspeed, Agfa Ektaspeed and Insight film were 0.917, 0.910, 0.894, 0.909 respectively. There was no significant differences between Az of Insight film and other films (p = 0.178). Conclusion : Theses results suggested that Kodak Insight film have the comparative diagnostic accuracy of dental caries with Ultraspeed and Ektaspeed films.

동시에 진단된 대장암·위암 중복암 2예

신영도,이상목,이기형,윤충 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.3

綜合病院에 入院한 結核性腦膜炎 患兒의 疫學的 觀察

尹聖道,李性寬 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

大邱市內 三大綜合病院에 1975年부터 1980年까지 6年間 小兒科에 入院한 結核性腦膜炎 患兒 253名에 대한 疫學的調査分析 結果는 다음과 같다. 結核性腦膜炎의 發生率은 男兒가 女兒보다 높고, 3세以下의 年少兒에서 高率이었고, 年度別로는 1975年을 起點으로 했을때 漸次減少하였으며, 季節的으로는 春季가 가장높고 秋季가 낮았다. 地域別로는 大都市外廓地가 가장높고, 다음이 農村, 中都市, 大邱市中心都의 順位였다. 出生順位別로는 끝아이에서 높고, 中間아이에서 低率이었다. 結核家族에서 發生率이 높았고 BCG未接種者에서 높았다. 發病에서 入院까지의 期間은 中期以後가 많고 症狀으로는 末期인 意識混濁을 同伴하는 患兒가 많았다. 症狀別로는 熱, 嘔吐, 痙攣, 意識不明등이 높게 나타났으며 治療期間은 7日以後가 34%, 8日에서 20日까지가 31%, 20日이후가 24%였다. 退院時의 治療成積은 漸定的인 退院當時 狀態에서 症狀이나 腦脊髓膜液性狀의 狀況으로 判定하여 好轉한 것이 51.7%, 惡化가 36.9%, 死亡이 11.4%이었다. 好轉率은 男兒가 女兒보다 高率이었고 年齡的으로는 年少兒가 年長兒보다 높았으며, 年度別로는 1975年을 起點으로 했을때 年度가 經過함에 따라 好轉率이 높았고, 季節的으로는 夏節에서 높았고, 地域的으로는 都市의 中心地는 높으나 外廓地는 가장 低率이었다. 出生順位別로는 中間아이에서 높고 첫아이에서 가장 낮았다. 傳染源이 있는 患兒에서 높았고, BCG接種兒에서 높았다. BCG와 傳染源이 같이 있는 BCG 群에서 高率이었고, 傳染源은 있으나 BCG 接種이 없는兒에서 가장 낮았다. 症狀別로는 意識混濁群이 가장 낮았고 頭痛郡이 가장 높았다. 發病해서 入院까지의 期間이 짧을수록 그리고 入院期間이 길수록 好轉率이 높았다. 끝으로 적극 협조해주신 慶北大學敎醫科大學 부속병원 소아과교실원, 계명대의과대학 소아과 교실원 및 파티마병원 소아과원 제위에게 심심한 감사를 표시하는 바이다. During the last 6 years since 1975, epidemiological studies were done on 253 children with tuberculous meningitis admitted in 3 general hospitals in Daegu. The result were as follows; 1) The statistical studies indicated a gradual decrease in the incidence after 1975. Concerning the age difference, the highest incidence was noticed in the group of the children under 3 years old, rate of the group was 57.3% of the total patients. Concerning sex differences, the incidence of the male patients were slightly higher than that of the female patients. Concerning the seasonal differences, its incidence in spring was found to be the highest. Concerning the areas, the incidence in the suburban area was highest and rural, middle urban and central area in the large city were followed. Concerning the birth order, the incidence was higher in last child than in first and middle child. The source of the infection was mainly familial and inicidence of the group with infectious source accounted for 36.5%. The incidence of the group inoculated BCG accounted for 39.1% of the total patients. The main chief complaints were drowsiness, convulsion, vomiting, headache and fever. Main complications of the disease were miliary tuberculosis, 17.0%, pulmonary tuberculosis, 9.5%, other tuberculous lesion, 2.0% and other diseases, 6.0%, respectively. Concerning duration between initial onset and admission within 10 days, 11-20 days and after 20days were 36.8%, 40% and 20.6%, respectively. Concerning duration of treatment were within 5days, 6-10days, 11-20days and more than 30days were 31.0%, 15.0%, 42.0% and 12%, respectively. 2) The prognosis of the diseases was analysed by various factors. Concerning the age difference, the patients less than 3 years old showed low rate of improvement and the rate of improvement increased with increase of ages. Concerning sex difference, the rate of improvement was slightly higher were in male than female cases. Concerning calendar year, the rate of the improvement was increased year by year. Concerning seasonal difference, the rate of the improvement was the highest in summer and autumn, winter and spring in that order. Concerning birth order, the rate of the improvement was highest in middle child and last and first child were in that order. The rate of the improvement were higher in the patients with infectious source than in those without sources and in the group of BCG vaccination than in that of non-vaccination. Concerning relationship between the rate of improvement and the history of infectious source and BCG vaccination, it was found that its rate of the patient with infectious source and BCG vaccination was highest paradoxically and the patient with infectious source and non-vaccination was lowest. Concerning the duration between initial onset and admission, the rate of improvement was higher in shorter period than that of longer period. Concerning the duration of the treatment, the rate of improvement was higher in the patients received longer period than that of shorter period. The rate of improvement was 35.1% in the group of the patients who showed disturbance in the consciousness already on the admission, while the group with headache was the highest rate with 73.7%.

[TEACOOH]-Montmorillonite 층간화합물의 형성 및 층 내에서의 고분자화 반응

윤도우,조성준 배재대학교 공학연구소 2005 공학논문집 Vol.7 No.1

Na-Montmorillonite와 10-Carboxy-n-decyltriethylammonium bromide (유기 양이온) 사이의 양이온 교환반응에 의해 얻어진 [TEACOOH]-Montmorillonite 층간화합물을 유기 단분자인 ε-caprolactone을 반응시켜 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 형성하였다. 이렇게 얻어진 [TEACOOH]-ε-caprolactone-Montmorillonite 층간화합물을 220oC의 온도 하에서 48시간 동안 가열하여 고분자화시켜 무기물질인 몬모릴로나이트와 유기 고분자인 폴리카프로락톤이 화학적으로 결합된 몬모릴로나이트/폴리카프로락톤 나노복합재료를 제조하였다. 고분자화반응을 수행한 후 얻어진 시료를 메탄올을 이용하여 추출한 뒤 고진공 하에 65oC로 24 시간 동안 건조시킨 후에 얻은 층간거리 값으로는 34.24 Å이 얻어졌다. [TEACOOH]-Montmorillonite intercalations complex obtained from Na-Montmorillonite and 10-Carboxy-n-decyldimethylethylammonium bromide(organic cation) was reacted with the monomer(ε-caprolactone) to achieve the [TEACOOH]-ε-caprolactone-Montmorillonite intercalations complex. From this intercalations complex Montmorillonite/Polycaprolactone Nanocomposite in which montmorillonite(inorganic material) is chemically linked with the polycaprolactone(organic polymer) was formed at 220oC for 48 h. The basal spacing for the sample obtained after polymerization, extraction with methanol and dried at 65oC in high vacuum for 24 h was 50.7 Å.

레이저 스페클간섭법에 있어서 스페클크기와 측정 한계에 관한 연구

윤성운,김경석,양승필,정현철,김정호,이도윤 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.1

The high coherence of laser beam has made it possible to observe interference effects even in the light scattered from rough surfaces. That's why, when object with a scattering surface is illuminated with laser light, we do see a speckled appearance due to random interference. This sort of unique property of laser speckle has brought into existence the new noncontacting techniques such as speckle metrology method of measuring deformation, displacement, and vibration etc of objects with high optical sensitivity. The measurable range of speckle metrology especially used to measure in-plane information, however, is limited by some factors, the so-called strain, rotation, tilt of surface and out of displacement perpendicular to the plane of analysis. This restrictions severly limits the measurable range of speckle metrology by causing the decorrelation of speckle patterns. It is the purpose of this paper to give a survey on the measurable limitation of speckle photography method that is one of speckle metrology. Namely we will discuss the mutual relationships and problems of each limitations adding the restriction of the largest and smallest displacement measurable with speckle methods.