3차원 전산화단층촬영 영상을 이용한 안면 연조직 두께 계측의 임상적 유용성

정호걸,김기덕,한승호,허경석,이제범,박혁,최성호,김종관,박창서 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.2

Purpose : To evaluate clinical usefulness of facial soft tissue thickness measurement using 3D computed tomographic images. Materials and Methods : One cadaver that had sound facial soft tissues was chosen for the study. The cadaver was scanned with a Helical CT under following scanning protocols about slice thickness and table speed; 3 mm and 3 mm/sec, 5 mm and 5 mm/sec, 7 mm and 7 mm/sec. The acquired data were reconstructed 1.5, 2.5, 3.5 mm reconstruction interval respectively and the images were transferred to a personal computer. Using a program developed to measure facial soft tissue thickness in 3D image, the facial soft tissue thickness was measured. After the ten-time repeation of the measurement for ten times, repeated measure analysis of variance (ANOVA) was adopted to compare and analyze the measurements using the three scanning protocols. Comparison according to the areas was analyzed by Mann-Whitney test. Results : There were no statistically significant intraobserver differences in the measurements of the facial soft tissue thickness using the three scanning protocols (p>0.05). There were no statistically significant differences between measurements in the 3 mm slice thickness and those in the 5 mm, 7 mm slice thickness (p>0.05). There were statistical differences in the 14 of the total 30 measured points in the 5 mm slice thickness and 22 in the 7mm slice thickness. Conclusion : The facial soft tissue thickness measurement using 3D images of 7 mm slice thickness is acceptable clinically, but those of 5 mm slice thickness is recommended for the more accurate measurement.

Upregulation of heme oxygenase-1 by ginsenoside Ro attenuates lipopolysaccharide-induced inflammation in macrophage cells

Kim, Sokho,Oh, Myung-Hoon,Kim, Bum-Seok,Kim, Won-Il,Cho, Ho-Seong,Park, Byoung-Yong,Park, Chul,Shin, Gee-Wook,Kwon, Jungkee The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.4

Background: The beneficial effects of ginsenoside species have been well demonstrated in a number of studies. However, the function of ginsenoside Ro (GRo), an oleanane-type saponin, has not been sufficiently investigated. Thus, the aim of the present study was to investigate the anti-inflammatory effects of GRo in vitro using the Raw 264.7 mouse macrophage cell line treated with lipopolysaccharide (LPS), and to clarify the possible mechanism of GRo involving heme oxygenase-1 (HO-1), which itself plays a critical role in self-defense in the presence of inflammatory stress. Methods: Raw 264.7 cells were pretreated with GRo (up to $200{\mu}M$) for 1 h before treatment with 1 mg/mL LPS, and both cell viability and inflammatory markers involving HO-1 were evaluated. Results: GRo significantly increased cell viability in a dose dependent manner following treatment with LPS, and decreased levels of reactive oxygen species and nitric oxide. GRo decreased inflammatory cytokines such as nitric oxide synthase and cyclooxygenase-2 induced by LPS. Moreover, GRo increased the expression of HO-1 in a dose dependent manner. Cotreatment of GRo with tin protoporphyrin IX, a selective inhibitor of HO-1, not only inhibited upregulation of HO-1 induced by GRo, but also reversed the anti-inflammatory effect of GRo in LPS treated Raw 264.7 cells. Conclusion: GRo induces anti-inflammatory effects following treatment with LPS via upregulation of HO-1.

Upregulation of heme oxygenase-1 by ginsenoside Ro attenuates lipopolysaccharide-induced inflammation in macrophage cells

Sokho Kim,Myung-Hoon Oh,Bum-Seok Kim,Won-Il Kim,Ho-Seong Cho,Byoung-Yong Park,Chul Park,Gee-Wook Shin,Jungkee Kwon 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.4

Background: The beneficial effects of ginsenoside species have been well demonstrated in a number of studies. However, the function of ginsenoside Ro (GRo), an oleanane-type saponin, has not been suffi- ciently investigated. Thus, the aim of the present study was to investigate the anti-inflammatory effects of GRo in vitro using the Raw 264.7 mouse macrophage cell line treated with lipopolysaccharide (LPS), and to clarify the possible mechanism of GRo involving heme oxygenase-1 (HO-1), which itself plays a critical role in self-defense in the presence of inflammatory stress. Methods: Raw 264.7 cells were pretreated with GRo (up to 200mM) for 1 h before treatment with 1 mg/ mL LPS, and both cell viability and inflammatory markers involving HO-1 were evaluated. Results: GRo significantly increased cell viability in a dose dependent manner following treatment with LPS, and decreased levels of reactive oxygen species and nitric oxide. GRo decreased inflammatory cytokines such as nitric oxide synthase and cyclooxygenase-2 induced by LPS. Moreover, GRo increased the expression of HO-1 in a dose dependent manner. Cotreatment of GRo with tin protoporphyrin IX, a selective inhibitor of HO-1, not only inhibited upregulation of HO-1 induced by GRo, but also reversed the anti-inflammatory effect of GRo in LPS treated Raw 264.7 cells. Conclusion: GRo induces anti-inflammatory effects following treatment with LPS via upregulation of HO-1.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

자산건전성 분류기준에 따른 대손충당금 적립제도에 대한 고찰

朴範鎬,丁光秀 홍익대학교 경영연구소 2003 경영연구 Vol.28 No.-

1999년 말 금융감독위원회는 은행의 여신관행을 개선하고, 자산건전성 분류제도가 국제적 정합성에 부합되도록 미래의 채무상환능력과 함께 연체기간 부도여부 등 금융거래 내용을 종합적으로 반영한 새로운 개념의 자산건전성 분류제도를 도입하였다. 본 제도의 기본 취지는, 당국은 최소한의 가이드 라인만을 제시하고, 금융권 스스로 자율적이고 합리적인 자산건전성 분류 및 대손충당금 적립체제를 구축하게끔 지원, 유도하는 것이었다. 또한 정보 데이터의 축적, 자체 여신 감리체제의 운용 및 신용평가모형의 활용을 통하여 여신관행의 선진화를 정착시켜 선진 금융 체제의 조기 정착을 달성하는 것이 그 궁극의 목적이었다. 하지만 새로운 자산건전성 분류 기준에 의한 대손충당금 적립제도는 우리나라의 금융기관들에 적용하는데 있어서 나름의 한계점들을 내포하고 있다. 본 연구에서는 새로운 자산건전성 분류기준에 의한 대손충당금 설정제도의 한계와 그 개선방향에 대하여 연구하고, 한국 금융기관에 적합한 모형이 무엇인지를 찾고자 하는데 그 목적을 두었다. 연구결과에 의하면 사후관리 중심의 자산건전성 분류가 아닌 사전, 사후 통합리스크관리시스템의 필요성을 도출하게 되었다. 따라서 사전, 사후관리가 균형을 이루어 하나의 시스템처럼 유기적으로 적용될 수 있는 통합리스크관리(total risk management)체계에 관한 실증적 연구가 이루어질 필요가 있다.

團體交涉을 위한 會計情報시스템에 관한 硏究

朴範鎬,金東出 홍익대학교 경영연구소 1991 경영연구 Vol.15 No.-

우리나라 物價變動會計制度의 導入方案에 관한 硏究

朴範鎬,宋在萬,李勉榮,蔡奎學 홍익대학교 경영연구소 1985 경영연구 Vol.9 No.-

As accounting is an outgrowth of society, we can say that the accounting system of each country is derived from its economic situation and from the people's outlook no economic values. Thus when the economic situation of one country is different from that of another country, and the outlook of the people of one country is different from that of another country, they the accounting system for changing prices as well as general accounting systems may be different. Actually accounting systems of different countries are not identical. The writers of this paper try to find an accounting system for changing prices suitable to out country. The writers review various theories on accounting systems for changing prices, survey accounting systems of various countries and basic patterns of such systems, and in vestigate the actual conditions of our country in order to provide accounting information which reflects the effect of changing prices and to give a practicable accounting system. In this paper, the writers state their opinions about accounting systems for changing prices as follows: 1)The demand for the publication of accounting information about the effect of changing prices upon the financial status and operational result of a business is a world-wide trend. Considering that our industries are now aiming at opening a capital market, we should establich an accounting system for changing prices in order to follow the world-wide current. 2) As we intend to follow the world-wide current, to get useful accounting information, and to get a practicable accounting system, the most suitable system for us is the current value accounting system The current value accounting system mentioned here does not provide information supplementary to that of the financial statements based on the historical cost but it provides a substitute of the current value financial statements for those based on the historical cost. Financial statements based on current values are standard statements. 3) In our country, there are no active studies or discussions on the accounting systems for changing prices. We need to set up an organization entirely responsible for the establishment of a desirable accounting system for changing prices, responsible for the establishment of guidelines for putting the system to use, and responsible for the coordination of the interests of those concerned.

人的資源評價모델에 관한 硏究

朴範鎬 弘益大學校 1981 弘大論叢 Vol.13 No.-

In approaching this problem I have attempted to point out the necessity for, and importance of, human resource accounting imformation in the light of the current accounting environment. This study will discuss a number of valuation models, dealing with human resources which have thus far been developed. The suthor has developed his own model by comparing the properties of various measuring models Its characteristics are (1) that among the existing measuring models, it is based on the clear logic of the method of economic values resting on beneficial values: (2) that it evaluates the values of human resources in an organization not by measuring values of the organization but by measuring and integrating values of individual members in the organization: and (3) that it accounts for the probability that an individual will remain in an organization. Escaping from the dimension of simple and general quantitative measurement, it especially tries to make dual measurements which are characterisitc in business accounting, using the capital maintenance concepts and operational approach. The author considers values of human resources as the sum of disconted present values of future service potential to be offered by the individual employees of an enterprise for the purpose of managing the enterprise, and, to measure it, following basic model is proposed: 1 E(V?????)=??????P???(t+1)??????-----------I???? (1+r)???? To solve the difficulties of obtaining values for I?????, in reality, the above equation is modified as follows to be a basic model of measuring value for human resources: 1 1 E(V????*)=??????P???(t+1)??????-----------I*???+??????------------ (Ra-ki) (1+r)???? (1+r)???? 1. 人的資源會計情報에 대한 要約 2. 人的資源會計測定의 基本構造 3. 人的資源會計測定 모델 1) 支出原價法 2) B. Lev와 A. Schwartz의 測定 모델 3) R. H. Hermanson의 測定 모델 4) 給與還元法 5) R. Likert의 組織價値測定 모델 6) E. Flamboltz의 個人價値測定 모델 7) W.J. morse의 測定 모델 8) P. Ogan의 測定 모델 4. 諸人的資源測定 모델의 特徵 및 開發 모델의 提示 1) 諸人的資源測定 모델의 特徵 2) 人的資源測定 모델의 提示

주식수익률 시계열관계에 의한 시장의 효율성 검증

朴範鎬 홍익대학교 경영연구소 2004 경영연구 Vol.29 No.-

대상 포진양 배열을 보인 다발성 에크린 나선종 1예

박현제,김문범,장봉석,오창근,장호선,권경술 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.4