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장애학생 관련 변인에 따른 비장애 학생의 통합태도 연구
오원석 ( Won Seok Oh ),남경숙 ( Kyung Sook Nam ),허명진 ( Myung Jin Huh ) 한국특수교육문제연구소 2006 특수교육저널 : 이론과 실천 Vol.7 No.3
장애학생 관련 변인에 따른 비장애 학생의 통합교육에 대한 태도 및 장애학생에 대한 친근감을 알아보기 위하여 본 연구를 수행하였으며, 연구 대상은 대구광역시 초등학교 5개교15학급 477명을 선정하였다. 연구 결과 장애학생의 통합에 대한 비장애 학생의 태도에 영향을 미치는 변인은 장애유형, 장애학생 성별, 장애학생의 청결상태이며, 영향을 미치지 않는 변인으로는 장애학생 부모의 관심도, 장애아 가정의 경제적 수준 그리고 장애학생의 학습 능력인 것으로 나타났다. The purpose of this study is to determine the attitudes for integration education and the intimacy with disabled students of Nondisabled students influenced by disabled students. For such purpose, 477 students of 15 classes from 5 elementary schools located in Daegu Metropolitan City were selected as the object of this study. Integrated Attitudes was measured through an investigation equipment by Oh Won-Seok and Seo-Yeong Ran which adapted and modified a testing document called Inclusion of Students who are Deaf or Hard of Hearing Inventory (ISDHH) invented by Hsin-Ling Hung(2005). The result indicated that the factors which influence the Attitudes of nondisabled students regarding integration with disabled students are the type of injury, the gender and the cleanness of the disabled student. The factors which do not influence the above are interests of the disabled student``s parents, economic level of the family and the learning ability of the disabled student.
해저케이블 비용 모델을 이용한 HVAC 해상변전소 적정 위치 선정에 관한 연구
원종남(Jong-Nam Won),문원식(Won-Sik Moon),허재선(Jae-Sun Huh),김재철(Jae-Chul Kim) 대한전기학회 2013 전기학회논문지 Vol.62 No.4
Development of the technologies for offshore wind power is proceeding actively and the installation capacity is continuously increasing because of its many advantages in comparison with the land wind power. Accordingly, project for Southwestern 2.5GW offshore wind power plant is in progress in Korea. Design of electric power systems for offshore wind power plant is very important due to its high investment and operational costs. Hence, it needs to be designed in order to minimize costs. This way can be employed in determining the installation location of offshore substation for HVAC wind power plant. According to the offshore substation site, MV inter-array cable and HV export cable lengths vary and they change a total cost regarding submarine cable. This paper represents cost models with variables which are MV inter-array cable and HV export cable lengths to locate the offshore substation for HVAC wind power plant. It is classified into submarine cable installation cost, reactive power compensator installation cost, ohmic losses, and unsupplied energy cost. By minimizing a total cost, an appropriate installation site of the offshore substation is determined.
Lys1110 of TRPM2 is critical for channel activation.
Kim, Taek-Keun,Nam, Joo Hyun,Ahn, Won-Gyun,Kim, Nam-Ho,Ham, Hwa-Yong,Hong, Chang-Won,Nam, Ju-Suk,Lee, Jongho,Huh, Sung-Oh,So, Insuk,Kim, Sung Joon,Song, Dong-Keun Biochemical Society 2013 The Biochemical journal Vol.455 No.3
<P>TRPM2 (transient receptor potential melastatin 2) is a non-selective Ca2+-permeable cation channel activated by ADPR (adenosine diphosphoribose) and H2O2. It is widely expressed in mammalian cells and plays an important role in the regulation of various cell functions. However, the mechanisms of TRPM2 channel activation are not fully understood. Previously, we reported that TRPM2 channel activation is induced by high intracellular Cl- concentration. In the present study, we investigated the functional role of Lys1110 in the membrane-proximal C-terminal region by site-directed mutagenesis. Replacement of the positively charged amino acid lysine (Lys1110) with the neutrally charged amino acid asparagine (K1110N) or the negatively charged amino acid glutamic acid (K1110E) generated mutants that failed to induce an increase in free cytosolic calcium concentration ([Ca2+]i) not only by intracellular injection of Cl-, but also by H2O2 or ADPR. However, a mutant generated by replacing the lysine residue with a positively charged amino acid arginine (K1110R) displayed channel activity similar to wild-type TRPM2. Interestingly, in the K1107N/K1110N double-point mutant, the impaired function of the K1110N mutant in response to ADPR and H2O2, but not to Cl-, was recovered. There were no changes in protein expression, membrane trafficking and oligomerization of the mutant channels. The extent of [Ca2+]i increase by H2O2 in HEK (human embryonic kidney)-293 cells expressing TRPM2 mutants was well correlated with the degree of susceptibility to H2O2-induced cell death. These results display the crucial role of a positively charged amino acid residue at position 1110 for TRPM2 channel activity.</P>
허갑범,이현철,임승길,송영득,차봉수,원영준,김선호,김경래,권석호,정보영,남수연,김태승,엄재화 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.2
Backgrounds: Pituitary hyperplasia can mimic pituitary adenoma. In MRI, enlarged pituitary gland is enhanced homogenously with upward convexity of the superior margin of the gland .The best definition of hyperplasia in the pituitary hyperplasia seems to be a multiplication of one or more cell types. But definition, etiology and clinical courses of this disease are not clear, Method : We reviewed clinical symptoms, MRI, and pathologic findindings in 6 patients with pituitary hyperplasia. Result: 1. Major clinical symptoms were headache(100%), visual field defect(84%), polyuria/polydipsia (64%), and irregular mensturation(32%). Other symptoms were amenorrhea(16%) and galactorrhea (16%). 2. Three of five cases showed abnormal responses to combined pituitary function test, 3. MRI findings were pituitary hyperplasia(4), macroadenoma(l), and microadenoma(1). 4. In two operated cases, there was no adenoma. One case showed hyperplasia of lactotroph cells, the other was hyperplasia of gonadotroph cells confirmed by the examination of immunocytochemistry. Conclusion : Pituitary hyperplasia should be considered in patients with enlarged pituitary gland without focal mass lesion. (J Kor Soc Endocrinol 12:155-164, 1997)
Cardiopulmonary function and scoliosis severity in idiopathic scoliosis children
Huh, Seokwon,Eun, Lucy Yougmin,Kim, Nam Kyun,Jung, Jo Won,Choi, Jae Young,Kim, Hak Sun The Korean Pediatric Society 2015 Clinical and Experimental Pediatrics (CEP) Vol.58 No.6
Purpose: Idiopathic scoliosis is a structural lateral curvature of the spine of unknown etiology. The relationship between degree of spine curvature and cardiopulmonary function has not yet been investigated. The purpose of this study was to determine the association between scoliosis and cardiopulmonary characteristics. Methods: Ninety children who underwent preoperative pulmonary or cardiac evaluation at a single spine institution over 41 months were included. They were divided into the thoracic-dominant scoliosis (group A, n=78) and lumbar-dominant scoliosis (group B, n=12) groups. Scoliosis severity was evaluated using the Cobb method. In each group, relationships between Cobb angles and cardiopulmonary markers such as forced vital capacity (FVC), forced expiratory volume in one second ($FEV_1$), $FEV_1$/FVC, left ventricular ejection fraction, pulmonary artery flow velocity, and tissue Doppler velocities (E/E', E'/A') were analyzed by correlation analysis linear regression. Results: In group A, 72 patients (92.3%) underwent pulmonary function tests (PFTs), and 41 (52.6%) underwent echocardiography. In group B, 9 patients (75.0%) underwent PFT and 8 (66.7%) underwent echocardiography. Cobb angles showed a significant negative correlation with FVC and $FEV_1$ in group A (both P<0.05), but no such correlation in group B, and a significant negative correlation with mitral E/A ratio (P<0.05) and tissue Doppler E'/A' (P<0.05) in group A, with a positive correlation with mitral E/A ratio (P<0.05) in group B. Conclusion: Pulmonary and cardiac function was significantly correlated with the degree of scoliosis in patients with thoracic-dominant scoliosis. Myocardial diastolic function might be impaired in patients with the most severe scoliosis.
Breeding of Light Pink Rose "Magic Pink" with High Productivity and Good Shape
Won Hee Kim,Kun Yang Huh,Seung Tae Kim,Eun Kyung Lee,Yong Nam Oh,Pil Man Park,Dong Woo Lee 한국육종학회 2007 한국육종학회지 Vol.39 No.4
A new standard rose cultivar 'Magic Pink' was bred from the cross between light yellow standard cultivar 'Medeo' and pink standard cultivar 'Veronica' at the National Horticulture Research Institute. The cross was made in 2001 and 'Magic Pink' was finally selected in 2006 after investigating characteristics for three years from 2003 to 2006. 'Magic Pink', a pink standard cultivar grows vigorously and has fashionable flower color. The major characteristics of this cultivar are 184.8 stems/m2/year in yield, 63.0cm in length of cut flower, 7.2 cm in flower diameter, 28.5 in petal number, and 10.4 days in vase life. This cultivar can be propagated by both cutting and grafting. The consumer's preference of this cultivar is relatively higher than that of control cultivar, 'Noblesse'.