간경변 환자에서 콜히친 사용에 의한 호중구성 백혈구감소증 1예

이호찬,이헌주,김용길,박재현,김성준,박준석 영남대학교 의과대학 2009 Yeungnam University Journal of Medicine Vol.26 No.2

Colchicine is an alkaloid that has been used for treating acute gouty arthritis, psoriasis, scleroderma and Behcet's syndrome. Colchicine decreased liver fibrosis in rats with carbon tetrachloride induced cirrhosis and in patients with many liver diseases. Therapeutic oral doses of colchicine may cause nausea, vomiting, abdominal pain and diarrhea. The adverse effect of colchicine associated with the dose is bone marrow suppression, and especially neutopenia. Neutropenia has often been reported in patients have taken an overdose of colchicine. We describe a 64-year-old female liver cirrhosis patient with neutropenia that was induced by a therapeutic dose of colchicine.

섬유강화 복합재료의 사출성형에 있어서 섬유배향에 미치는 성형조건의 영향

이동기,한길영,김성용 朝鮮大學校 機械技術硏究所 2000 機械技術硏究 Vol.3 No.2

Injection molding is a very important industrial process for the manufacturing of plastics objects. During an injection molding process of composites, the fiber-matrix separation and fiber orientation are caused by the flow of molten polymer/fiber mixture. As a result, the product tends to be nonhomogeneous and anisotropic. Hence, it is very important to clarify the relations between separation orientation and injection molding conditions. So far, there is no research on the measurement of fiber orientation using image processing. In this study, the effects of fiber content ratio and molding condition on the fiber orientation-angle distributions are studied experimentally. Using the image processing method, the fiber orientation distribution of weld-line parts in injection-molded products is assessed. And the effects of fiber content and injection molding conditions on the fiber orientation functions are also discussed.

생체분해성 고분자의 특성 및 의학적 응용

이진호,최선웅,강길선,노승무,민병무,김용백,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

"Biomaterials" are nonviable materials used in medical devices, intended to interact with biological systems. They should have "biocompativility", which is defined as the ability of materials to perform with an appropriate host response in a specific application. It includes many materials that are often classified as biomaterials. Metals, ceramics, polymers, glasses, carbons, and composite materials are some examples. Among them, biodegradable polymers are discussed in this revies article. Since a biodegradable polymeric implant does not have to be removed surgically once it is no longer needed, biodegradable polymers are of value in short-term applications that require only the temporary presence of a polymeric implant. Main short-term medical applications of biodegradable polymers include the temporary tissue scaffold, the temporary adhesion barrier, the drug delivery device, and the multifunctional implant. In this article, the properties, processing methods, and medical applications of the biodegradable polymers are reviewed.

초음파 및 Phased Array를 이용한 터빈 블레이드 루트부 건전성 평가에 관한 연구

길두송,박상기,조용상,이상국,허광범 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1

Power plant is consisted of many component parts for the generation of the electricity, and occasionally, turbine equipment may be caused in break-down because of the damage of the blade root. Phased array ultrasonic testing system has become available for practical application in complicated geometry such as turbine blade root, tenon, disc in power industry, This research describes the characteristics of phased array ultrasonic testing signal for various type of blade roots in thermal Power Plant turbines. This application of Phased array ultrasonic testing system has been promoted mainly to save inspection time and labor cost of turbine inspection. The characteristic of phased array ultrasonic testing signal for power plant component in very simple to understand but to difficult for perform the inspection. This paper is focused on the safety of the turbine equipment by the ultrasonic measurement and phased array analysis. As a result of the test through ultrasonic and phased array method, we have concluded that the main damage in these turbine blade root parts could be generated by the concentrated stress and centrifugal force.

한국인에서 다변성 D12S391 유전좌의 집단유전학적 연구

이용욱,김성민,구태완,이혜린,강일호,한길로,이혜승,황적준 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

The hypervariable short tandem repeat(STR) locus D12S391 was investigated in a Korean population. A total of 14 alleles were detected by size under denaturing conditions in 517 unrelated individuals. To confirm all of the alleles detected in a Korean population, a total of 34 fragments were sequenced. Prior to allele designation, we constructed the allelic ladders containing 11 alleles sequenced in this study. Allele 18 is the most common with a frequency of 0.281 in Koreans, and one variant allele 19.3 which have been confirmed by sequencing, was detected. The observed heterozygosity, the power of discrimination (PD), and the mean exclusion chance (MEC) for the locus D12S392 is 0.781, 0.946 and 0.652 , respectively. No deviation from Hardy-Weinberg equilibrium was observed in a Korean population (p=0.557). In the 424 meioses in 105 Korean families confirmed using other 17 STR loci, no mutation was detected in locus D12S391. The STR locus D12S391system is useful both for the analysis identification and parternity.

Sodium Dodecyl Sulfate의 분해반응에 대한 속도론적 연구

이길준,김종용,박병각 嶺南大學校 環境問題硏究所 1994 環境硏究 Vol.14 No.1

하천수에서 분리해 낸 SDS(Sodium Dodecyl Sulfate) 분해균주에 의하여 분해균주량의 변화와 SDS의 농도변화를 주어 SDS를 분해시킬 때 그 분해반응을 속도론적으로 연구하였다. 실험결과 SDS의 분해를 BOD로 표시하여 분해률을 측정한 속도식은 1차로 나타남을 알 수 있었다. 그리고 분해균주량의 변화와 SDS농도의 변화에 따른 속도상수는 분해규준량에는 영향을 받지 않으나 SDS의 농도에는 영향을 받음을 알 수 있었다. 그리고 활성화에너지는 5.304kcal/mol, 활성화 파라메타인 ???와 ???는 각각 4.69kcal/mol, -56.90 e.u.임을 알았다. Kinetic studies were carried out for change in BOD of SDS degradating microorganism isolated from river water. It is found that the decomposition of SDS is first order. Rate constants for the decomposition of SDS and its degrading microorganism found not to have an influence on variation of SDS-degrading microorganism but have an influence on SDS concentration. And thermodynamic parameters, Ea, ???? and ????, were obtained the value of 5.304kcal/mol, 4.69kcal/mol and -56.90 e.u., respectively.

A. 高校 科學 (生物·地球科學) 및 數學科 探究學習의 評價模型 定立과 評價紙 開發

李相協,權炳奎,林在圭,孫文求,吳岱燮,楊洪準,梁承榮,姜用熙,林成圭,金正遠,金吉民,兪正在 경북대학교 과학교육연구소 1982 科學敎育硏究誌 Vol.6 No.-

Currently the evaluation of high school science and mathematics learning has been too much knowledge-centered without concerning the inquiring ability or scientific attitude. This study, therefore, was made for the purpose of establishing of evaluation model for high school science (biology and earth science) and mathematics learning and its evaluation items. In this paper, the research was done about three fields, biology, earth science and mathematics. 1. For the biology, the evaluation methods of inquiry learning were studied with the foreign references, and proper evaluation items were suggested. 2. For the earth science, after analizing 5 kinds of earth science textbook of current using in high school, essential 19 items were selected. 5 of them were tested in test group and control group, then, the results were analized. 3. For the mathematice, the teaching elements of「Set」and「Flow chart」in mathematics (Ⅰ) were selected and structured. Detailed teaching objects were established and evaluation items were introduced.

트랙션 시브의 마모특성 연구

이강용,이길호 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.2

A laboratory testing machine is manufactured to examine the relationship between wear amount and hardness. Wear characteristics are observed with the traction sheaves of BHN 211-245 and wire rope of BHN 370 using acoustic emission method. The empirical relations between wear amount and hardness as well as between total acoustic emission count and wear amount are obtained. The empirical results show that the relationship between wear amount and hardness is not inversely proportional and the one between total acoustic emission count and wear amount is linear. The wear amounts of traction sheave T1 and T2 are the minimum and nearly constant in the ranges of BHN 235-245 and BHN 225-245, respectively.

도시하천의 환경 친화적 개선방안에 관한 조사연구

이길영,권득용,김영안,한천규 대전대학교 산업기술연구소 1999 산업기술연구소 論文集 Vol.10 No.1

The three main steams flowing through Taejon have some serious problems to be solved or improved. They are : First, the uniform cross section of the rivers should be changed. Second, the extension of the riverside road should be reconsidered. Third. the neighborhood parks on the flood plain should be modified. Fourth, the flood plain parking place must not be constructed. Fifth, the ecosystem will be destroyed by the structure constructed along the rivers. In this study, we suggest that the investment and research on the development of the new technology for the setting the rivers in natural condition should be needed now and the continuous investigation and long-term plan to preserve the ecosystem of the rivers should be required. The environmental conditions of Taejon-stream, Yudung-stream and Kap-stream are indicators of the standard of living of the citizens in Taejon. Now is the time to reconsider the careless construction around the rivers and to prepare the long-term plan for the protection of the ecosystem and natural environment.

土木科 模型 敎育課程 修正 開發 硏究

李與吉,金芳植,趙客璡,成基泰 忠州大學校 1987 한국교통대학교 논문집 Vol.21 No.-

For reasonable curriculum modification and development corresponding with training to competent middle-level, engineers as educational object of Technical Junior College this research was carried out as following process; 1. Collection and analysis of present curricurn in civil engineering department of domestic Junior College including the curriculum of foreign Junior College. 2. Organization of advisory committee for industry school cooperation and visiting industry and interview 3. Organization of all Korea Civill engineering department chief Committee 4. Result of research through the questionnaire for all Korea representative industry and academic could be summarized as follows; 1) wide contact between college education and industry field should be strengthened, and field experimental education was strengthened to consider of ability, and construction management was edited Compulsory major 2) For the adaption trend of variety and subdivision of construction skill E.D.P.S education was edited compulsory. 3) The curriculum was endeavoured to fundamental science 4) The curriculum enlarged the range of the optional subject which is able to manage the flexible curriculum for characterization of each Local junior college and endeavoured consideration of field adapting ability by classifing the civil design into construction design and integration, Hydraulic design and integration, Earth design and integration 5) The curriculum of academic theories and experiments were unificated into single subject for the purpose of flexible management 6) The curriculum was edited in the ratio which is 20 to 80 between liberal and majoring arts in presentation on the basis of all accounts of opinion from the academic and field worker, and emphasized the importance of language education industrial english conversation because of demand of much ability along with foreign advance of construction technique 7) The curriculum was emphasity of the field experiments training based on the information by all opinion. By operating this curriculum, it is expected that the relationship between industry and academic will be efficiently considered 8) the present system of second grade National Technical Qualification Test while at college is in high level similar to the first grade, and has been required some of the majoring academic the-ories to pass of it's qualification concentrically. Because of this reason, it must be efficiently studied to educated prospective technicians demanding from industry organization and academy according to the educational gaal of Junior Technical College for improvement plan