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Effects of dietary supplementation with probiotic CS-A on performance in broiler chickens
Seong Soo Kang1*, Se Eun Kim, Ara Go, Kyung Mi Shim, Chun Sik Bae, Chang Jong Moon, Sung-Ho Kim, Jong-Choon Kim, Jin-Cheol Yoo, Seung Sik Cho 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3
Probiotics, enzymes, organic acids, oligosaccharides, antioxidants, and other functional materials are actively being explored as alternatives to antibiotics. Probiotics include live beneficial microorganisms that colonize the intestinal tract and competitively inhibit attachment and growth of harmful microbes. Probiotics also increase feed efficiency by assisting in nutrient absorption and digestion. The current study was conducted in order to evaluate the effect of a new probiotic, CS-A, as a dietary supplement of a fermented product on growth performance, feed intake, and feed conversion efficiency in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Antibacterial and anti-inflammatory effects of CS-A were investigated in vitro and the in vivo effects of a constant concentration of supplemented CS-A on growth rate and feed efficiency were evaluated. In addition, the safety of CS-A was assessed by examination of common symptoms and mortality. Determination of minimal inhibitory concentration revealed an excellent antibacterial effect of CS-A. Cytotoxicity was low and anti-inflammatory effects were achieved at the effective concentration of CS-A. Supplementation with 0.1% CS-A resulted in a feed efficiency score of 1.84 in broilers, compared to 2.00 in the control group. There were no adverse clinical findings, necropsy findings, hematology, and altered serum biochemistry parameters, and no mortality. Thus, it is concluded that CS-A is safe and effective as a feed additive.
Pbo-B₂O₃계 저융점유리에 코디어라트 Filler 첨가에 따른 특성에 관한 연구
강원호,이헌식,홍유식,이경희 明知大學校 産業技術硏究所 1989 産業技術硏究所論文集 Vol.8 No.-
On sealing glass for Joining with the ceramic substrate of which the coefficient of thermal(C.T.E) expansion is ??, the properties of sealing glass due to change the content and particle size of filler were studyed. Mother glass used PbO-B₂= 3 system glass and Ceramic filler used cordierite that have low dielectric constance and C.T.E. of ?? Optimum content of filler cordierite for matching C.T.E. withe ceramic substrate is 15 ∼ 17 wt.% and MOR in maximum at 15 wt.%. Sealing glass which prepared with coarse filler in average particle size have a good flowbility, but have a poor resistance to acid and high dielectric contance. The particle size range of cordierite in optimum properties is 270 - 400 mesh.
康景植 명지대학교 공학기술연구소 1986 공학기술연구소 논문집 Vol.1 No.-
An individual makes an endeavor for maximum of their usefulness. An usefulness is involved in a rich through consume and an usefulness to investment is involved in the change rate of rich. In this paper, we have study 1) the individual attitude for the risk 2) a relation of cost functions 3) measure of danger refrainment 4) the attitude of danger under representation function. We have a result that expect usefulness with usefulness function decide a question about individual investment behavior.
康景植,閔雄基 명지대학교 공학기술연구소 1987 공학기술연구소 논문집 Vol.2 No.-
This paper is to show how to determine the optimal Lot Sizing Rules in a hierarchical Production System. Four selective Lot Sizing Rules, shown excellent among those 9 Lot Sizing Rules in recent studies, are evaluated in terms of production and inventory cost. Six typical demand patterns are generated, and unit production costs and set-up costs are considered as a function of different levels of production system. Also were calculation the total cost of 16 Lot Sizing Sequence generated by the permutation of the four selective rules. Decisions are made on the optimal Lot Sizing Rules at the minimum total cost. Since the total cost varies as a function of the lot size, the upper and lower limit of the lot size is to be estimated within the range of the tolerance level of the total cost. The Economic Lot Range, which the variation of the total cost is negligible, is determind by the two limits of the lot size. Experimentation shows the range is wide enough to provide a greater flexibility in management decision. As the lot size spans from its lower to upper limit, the corresponding penalty costs occur. A functional relationship between total cost and lot size is established through the use of sensitivity analysis. Then the suggested model lays down new criteria by which the penalty cost is optimal.
STS 316 스테인리스 강의 고온 피로 균열성장에 미치는 하중 및 인장유지 시간의 효과
강경식,임병수 成均館大學校 科學技術硏究所 1999 論文集 Vol.50 No.1
As high temperature equipments are operated under the cycle composed of start-up, steady operation and shut down procedures, cracks existing in the components usually experience fatigue loading of trapezoidal waveshapes. An investigation has been conducted to evaluate the effects of load and hold time on high temperature fatigue crack growth in STS 316 stainless at 650℃. High temperature fatigue crack propagation experiments conducted under the load condition of 230 and 270MPa. and conducted over a wide range of hold times of 0, 0.1, 1 and 10 hours for each load condition. The results of this study can he summarized as follows : (1) As load increased from 230MPa to 270MPa and tensile hold time from 0 to 10 hours, average load line displacement rate per cycle and average crack growth rate per cycle increased gradually. (2) For prediction of creep damage, a linear superposition model was adopted. In the case of 0.1, 1 hour tensile hold time, the predicted creep crack growth rate was greater than the practical creep crack growth rate, which proved that creep-fatigue interaction had existed.
강형모,권경우,김기길,정의식,허영환 한밭대학교 산업과학기술연구소 1994 논문집 Vol.2 No.-
This paper presents results of the development of centerless feeding system which are applicable to bearing metal processes. As a result, the feeding system can be applied to automatic surface finishing on the bearing metal process such as bush, and has greatly effects on the increase of the prodnctiving and the decrease of the man power an effect on increase the productivity and decrease the man power and effect on increase the productivity and decrease the man power of the bush machining process.
생산라인의 설비효율 증대 확보를 위한 CBT System구축에 관한 연구
강경식,나승훈,김동환 한국경영과학회 1994 한국경영과학회 학술대회논문집 Vol.- No.1
Developing the safety training program has been a major research topic in C B T as well as in traditional teaching and learning. With regard to determining learning control in CBT, it is important to consider not only the characteristics of learning tasks but also student's individual difference. In this regard, the purposes of this study are to develop the CBT program as well as animation program in order to increase the student's performance.
최강원,오명돈,배현주,백경란,박선양,김병국,신완식,강문원,진종률,박종원,김춘추,김동집,한지숙,민유홍,이선주,고윤웅 대한화학요법학회 1993 대한화학요법학회지 Vol.11 No.2
Fluconazole의 진균 감염증 예방 효과와 안전성에 관하여 3개 대학병원에서 관해유도화학요법을 받는 급성 백혈병환자를 대상으로 무작위 배정법과 너도나도 누가림법에 의하여 연구하였다. 모두 62명의 환자에게 fluconazole(100㎎ bid) 또는 nystatin(1,000,000IU/day)을 무작위로 투여하였다. 투약은 관해유도화학요법과 같은 날짜에 시작하여 호중구수가 1,000㎣이상으로 회복되거나 진균 감염증이 확인되거나 의심되어 Amphotericin-B를 시작하거나, 약과 관련된 부작용이 나타날 때까지 계속하였다. 진균 colonization은 fluconazole군에서 감소하였으나 nystqatin군에서는 증가하였다, 표재성 진균감염증으로 nystatin군에서 C. albicans 진균혈증 1례와 C.parasilosis 진균혈중 1례가 발생하였다. 경험적 항진균요법으로 Amphotericin-B를 투여한 경우는 fluconazolerns 34명중 7례(21%), nystatinrns 28명중 10례(36%)였다(p<0.05). Fluconazole군과 nystatin군 사이에 부작용이나 사망률에 차이는 없었다. 결론적으로, fluconazole은 관해유도화학요법을 받는 급성 백혈병환자에서 진균의 colonization을 줄이는데 효과적이고 안전한 항진균제이다. We made a randomized, double-blind, multicenter trial to compare the efficacy and safety of fluconazole with nystatin for prevention of fungal infections in patients with acute leukemia. Sixty-two adult undergoing remission induction chemotherapy for cute leukemia were enrolled. Patients were randomly assigned to receive either fluconazole (100㎎ bid) or nystatin(1,000,000IU×6/day) with corresponding placebo. The study drug was started in initiation of chemotherapy and continued until recovery of neutrophil counts(>1,000/㎣), development of proven or suspected invasive fungal infection, or the occurrence of drug-related toxicity. Fungal colonization decreased in fluconazole(F) group, however increased in nystain(n) group. Superficial fungal infection occurred in 1 of 34 F group, whereas invasive fungal infection developed in 3 of 28 N group. Empirical amphotericin-B therapy was given in 7 of 34(21%) F group and 10 of 28(36%) N group(p>0.05). The incidence of drug-related side effects and overall moratlity were similar in both study groups.