운동의 Biomechanic적 변인들의 측정 및 분석을 위한 Micro Computer용 Software의 개발

고흥환,황인승 연세대학교 대학원 1986 延世論叢 Vol.22 No.1

뇌경색환자의 한방치료 후 생화학적ㆍ혈액학적 변화에 대한 임상적 고찰

고흥ㆍ이은 세명대학교 한의학연구소 2001 韓醫學硏究所 論文集 Vol.3 No.-

We check complete blood count and bio-chemistry three times(onset, 2 weeks later after treatment, 4 weeks later after treatment) for estimating the oriental medicine treatment's influence on hemodynamic, blood viscosity change in the cerebral infarction patients. Though RBC, hemoglobin(Hgb), and hematocrit(Hct) are decrease significantly after 2 weeks treatment and continue 4 weeks, their change are within normal limit. We suggested that the oriental medicine treatment in the cerebral infarction is not influence on blood viscosity and hemodynamic change.

運動種目別 筋運動 感覺의 比較硏究 : - 태권도, 축구, 농구, 야구를 中心으로 -

高興煥,金常圭,李愚萬 연세대학교 교육대학원 1985 연세교육과학 Vol.26 No.-

The purpose of this stuffy was find out any relationship between specific segmental kinesthesis and particular shorts using several different sports athletes. A total of 20 (5 athletes for each event) subjects were randomely selected among the athletes in "Y" university athletes clubs of Taekwondo, football, basketball, and baseball. The kinesthesis test used in this study were Horizontal space test of the upper limbs, Vertical space test of the upper limbs, Horizontal space teat of the lower limbs and Vertical space test of the lower limbs. The results of this stuffy were as follows; 1. In Horizontal kinesthesis of the upper limbs, the athletes using the upper limbs much such as basketball and baseball players wore superior in the score to those using the lower limbs much like Taekwondo athletes and football players. 2. In Vertical kinesthesis of the upper limbs, the athletes using the upper limbs much such as basketball and baseball players were superior in the score to those using the lower limbs mach like Taekwondo athletes andfootball players. 3. In Horizontal kinesthesis of the lower limbs, athletes using the lower limbs much were superior in the score to those using the upper limbs, much wereas the athletes using the lower limbs much were inferior in the score to those of others. 4. In Vertical kinesthesis of lower· limbs the athletes using the lower limbs such as Taekwondo athletes and football players were inferior in the score to those of using the upper limbs much like basketball and baseball players. 5. In kinesthesis of upper limbs, the players using the upper limbs much were superior in the score to those using the lower limbs much like Taekwondo athletes and football players born in vertical and Horizental kinesthesis, but in kinesthesis of the lower limbs, all the athletes were the same in Horizental kinesthesis. And in Vertical kinesthesis, the players using the upper limbs much were superior in the cootie to those of using the lower limbs much like Taekwondo athletes, and football players.

Nuclear Factor I-C 결손 생쥐에서 상아모세포의 형태학적 특징

고승백,이창섭,이난영,이상호,김흥중,박주철 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

NFI-C K/O 생쥐에서는 상아모세포의 분화과정에 이상이 초래되어 상아질 형성에 이상이 생기고 치근 형성이 불완전하게 이루어지는 것으로 알려져 있으나 이에 대한 명확한 기전은 잘 알려져 있지 않다. 상아모세포가 분화하여 정상적으로 상아질을 형성하기 위해서 핵과 세포질이 극성을 띠고 잘 조직화되어야 하며, 이 과정에서 다양한 세포사이 결합장치들이 중요한 역할을 하는 것으로 알려져 있다. 본 연구에서는 NFI-C K/O 생쥐에서 상아질 형성에 이상이 생기는 것이 상아포세포의 형태학적 변화와 세포사이 결합장치들이 기능을 하지 못한 결과에서 기인한 것인지 알아보기 위하여, NFI-C K/O 생쥐에서 발생한 비정상적인 상아모세포들을 광학 및 투과 전자현미경을 이용하여 형태학적으로 관찰하고, Zo-1과 occludin의 발현을 면역조직화학적으로 관찰하여 세포사이 결합장치들의 분포를 확인하여 다음과 같은 결과를 얻었다. 1. 광학현미경 소견에서 NFI-C K/O 생쥐의 전치부 상아모세포는 세포 극성이 상실되고, 여러 층으로 배열되어 있었으며 상아질에 많은 세포들이 함입된 것과 같은 비정상적인 상아질의 소견을 나타냈다. 반면에 NFI-C K/O 생쥐의 구치부 상아모세포는 치관부에서는 잘 조직화된 소견을 보였으나 치근 형성 부위에서는 세포 배열이 불규칙해지고 세포 극성이 상실되었다. 2. 투과 전자현미경 소견에서 NFI-C K/O 생쥐 전치부의 비정상적인 상아모세포는 둥근 형태로 세포 사이 간격이 넓으며 폐쇄연접과 같은 세포사이 결합장치들이 전혀 관찰되지 않았다. 3. Zo-1의 면역조직화학적 염색에서 NFI-C K/O 생쥐의 전치부 법랑모세포의 근위부와 원위부에서 ZO-1이 강하게 발현되었으나 비정상적인 상아모세포에서는 ZO-1의 발현을 관찰할 수 없었다. 4. Occludin의 면역조직화학적 염색에서 정상 생쥐의 전치부 상아모세포에서는 occludin의 발현이 관찰되었으나 NFI-C K/O 생쥐의 비정상적인 상아모세포에서는 occludin의 발현이 관찰되지 않았다. 이상의 결과를 종합하여 볼 때 NFI-C의 결손은 상아모세포의 분화 이상을 초래하고 비정상적으로 상아질을 형성하는 과정에 세포사이 결합장치의 상실과 같은 형태학적인 변화의 중요한 요소로 작용하는 것으로 생각된다. NFO-C null mice demonstrated aberrant odntoblast differentiation and thus abnormal dentin formation while other tissues/organs in the body, including ameloblasts, appear to be unaffected and normal. However, little is known about the mechanism of NFI-C function in odontoblast differentiation and dentin formation. Odontoblasts are tall, highly polarized cells that are responsible for formation and maintenance of the predentin and dentin. An indication of their polarity is the acquisition of specialized intercellular junctions. As predontoblasts differentiate into odontoblasts, they are joined and attached at the apical end by well developed terminal webs of cytoskeletal actins, and associated tight as well as adherent njunctions. In this study, in order to investigate if disruption of the NFI-C gene interferes with formation of a specific or other structural proteins of the intercellular junctions, we examined morphological charcteristic of the aberrant odontoblast in NFI-C null mice using light and electron microscope. In addition, we determined the expression of major structural proteins of intercellular junctions, ZO-1 and occludin, during the differentiation of odontoblasts using immunohitochemistry. The results were as follows: 1. In light microscopy, abnormal odontoblasts of incisors of the NFI-C null mice were round in shape, lost their polarity, and trapped in osteodentin-like mineralized tissue. Mutant molars have relatively normal crowns, but short and abnormal differentiating adontoblasts in root formation area. 2. Electron microscopy of abnormal odontoblasts revealed the dissociation of the round osteoblast-like cells, the loss of their cellular polarity, and the absence of an intercellular junctional complex known as the tight junctions. 3. A mutant incisor showed labeling for ZO-1 at the proximal and distal ends of secreting ameloblasts, while staining for ZO-1 was not observed in the abnormal odontoblasts. 4. A normal incisor showed immunoreactivity for occludin in the differentiating odontoblasts. However, staining for occludin was not observed in the abnormal odntoblasts of mutant incisor. These results suggest that NFI-C gene causes dissociation of odontoblast and thus abberant odontoblast differentiation and abnormal dentin formation by interfering with the formation of intercellular junctions.

자궁경부암 Ia기의 임상적 고찰

노흥태,고지환 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

In 1995, The Cancer Committee of the International Federation of Gynecology and Obstetrics(FIGO) subdivided stage Ia cervical cancer into stage Ia1, tumor which invades the cervical stroma to a depth of 3.0 mm or less, and stage Ia2, tumor which invades the cervical stroma to a depth of 3.0 - 5.0 mm and a horizontal spread of 7 mm or less. We conducted this retrospective study in order to evaluate the result of therapeutic approach in patient with stage Ia cervical cancer. To investigate the clinical and pathological aspect of cervical cancer Ia1, a retrospective study was made on 62 cases, histological reconfirmed surgical specimen, which had been treated during the period from January, 1995 to October, 1999 at department of Obstetrics and Gynecology, Chungnam National University, Daejeon, Korea. The age ranged from 25 to 64 years and median age 41.8 years. In 62 cases, mean parity was 2.34. In 42 cases (67.8%) incidentally found through the routine Pap smear, in symptomatic group most frequently initiating symptom was vaginal bleeding (19.4%). Pap smear was done in all cases, the results reveals CIN Ⅲ in 51.5% and carcinoma in 32.3%. The corresponding rate of Pap smear was done 39.8%. The type Ⅰ hysterectomy was performed in 34 cases, and the type Ⅱ hysterectomy wan done in 24 cases of stage Ia1 disease and the type Ⅲ hysterectomy was done in 4 cases of stage Ia2 disease. Postoperative complication was in 6 cases, in which was bladder dysfunction in 2 cases, wound hematoma in 2 cases, wound infection in 2 cases. In conclusion, preoperative correct diagnosis of stage Ia cervical cancer was not easy. Based upon meticulous analysis of Pap smear, colposcopy and biopsy finding, more liberal use of diagnostic conization should be done for correct diagnosis.

尖端産業團地의 開發과 地域發展 : 淸州「테크노-빌」을 中心으로 A Case of Chongju Technoville

조흥수,고영구 안성산업대학교 1994 論文集 Vol.26 No.-

High-tech industrial parks are a version of technoville in Korea in respect of providing a complex of industry, research, high-level education and housing function. The development of High-tech industial parks raims to promote national economy and balanced regional growth together. This paper illustrates the expected impacts throughout the national-wide level as well as local level and points out the necessity for various subsidizations from central govemment together with formulation of special law to promote them. The new technoville planned in the Chongju suburb is not only defferent from existing high-tech industrial parks and technopolis, but embodies a new concept of development. That is, the techonville is organized by local provincial government. The industrial park emphasizes the production orientation with the ville landscape and function of its residential and recreational area. There are many highly desirable locational advantages to the area such as the international air port under construction nearby, Taeduck Researth and Development Center, and an affluent overflow of skilled labour from the capital region. Furthermore, a favorable industrial linkage with existing industrial parks and rural industrial estate provides outstanding locational characteristics which can not be found in any other part of the country.

생강나무 잎과 가지의 정유성분 비교

고건우, 홍열, 임흥빈 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

-본문참고-

지역마케팅 전략수립을 위한 구매력지수 측정

조흥수,고윤배 안성산업대학교 1997 論文集 Vol.29 No.2

This research focuses on introducing buying power index(BPI) as area marketing tool and estimating market potentials of 18 major cities. Buying power index measures the overall market power in each areas. The result can be use to evaluate market demand for retail and advertising strategies. We use 3 variables ; population of paticular regions, retail sales amount and disposable income to produce buying power index. This article concludes with some recommendations on the practical use of the index and future study.

외상성 교합으로 인한 어린이의 치주질환

최병재,고동현,김성오,이제호,손흥규 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

외상성 교합은 교합력의 결과로서 치주조직에 가해지는 손상이다. 주된 증상은 치아의 동요도이고, 통증, 타진에 민감, 열에 민감한 증상이 동반될 수 있으며 교합력에 의해 치아가 이동을 할 수도 있다. 만성으로 진행시 치아의 과도한 교모가 나타나며 방사선학적으로 치근막 공간의 비후, 치조백선의 비후, 치조골의 방사선 투과성, 치근흡수 등이 나타날 수 있다.외상성 교합은 치주질환의 원인과 관련되어 있다. 증가된 치아동요도를 야기하며 외상성 교합 자체는 치은염과 치주낭을 발생시키지 않으나 국소적 치태와 염증이 존재하고 있는 하에서 골소실, 치주낭이 발생할 수 있다. 치은퇴축은 외상성 반월, 맥콜스 팽윤, 스틸만 균열의 형태로 나타난다. 본 증례는 하악 유견치 부위의 치주질환을 주소로 내원한 5세 남아로서 상하악 유견치의 조기 접촉에 의해 하악 좌우측 유견치의 중증도의 동요도, 교합마모, 치은 퇴축, 치조골 파괴의 증상이 나타났기에 보고하는 바이다. Trauma from occlusion(TFO) is injury to the periodontal tissue as a result of occlusal forces. Mobility is a common clinical sign of occlusal trauma. In acute occlusal trauma, this may be accomanied by pain, tenderness to percussion, thermal sensitivity, and pathologic tooth migration. Chronic occlusal trauma may be marked by excessive wear and gingival recession. Radiographic finding include a widened periodontal ligament space, radiolucence and condensation of the alveolar bone, and root resorption. TFO is related to the pathogenesis of periodontal disease. It can cause increased tooth mobility. TFO itself does not initate or aggravate marginal gingivitis or initiate periodontal pockets. Active trauma can accelerate bone loss, pocket formation and gingival recession depending on the presence of local irritants and inflammation. Gingival recession associated with occlusal forces includes traumatic crescent, McCall's festoon and Stillman's cleft. TFO plays a minor role in the pathogenesis of early to moderate periodontitis. A 5-year-old male visited Yonsei University Pedodontics clinic with a chief complaint about gingival recession. Mobility, excessive wear, gingival recession were detected by clinical exam on the both mandibular deciduous canine. On the radiographic view, vertical alveolar bone loss was observed on both mandibular deciduous canine.

제7차 교육과정에 따른 함수영역의 수준별 문항개발 및 평가방법

박대연,고안상,유흥상,김윤배 전주대학교 교육문제연구소 2000 敎育論叢 Vol.15 No.-