시간 경과에 따른 부가중합형 실리콘 인상재의 수소 발생

이근우,김경남,고영무 大韓齒科器材學會 1995 대한치과재료학회지 Vol.22 No.1

Clinical reports have indicated that there occurs many bubbles on the surface of the gypsum model because of the hydrogen release from the addition silicone impression materials. Recently the products containing hydrogen absorber have been being developed but not perfect yet. In this study, 4 type Ⅲ dental stones(New fujirock ; G.C., New Plastone ; G.C., MG dental stone ; Maruishi, Suprastone ; Kerr) was poured into the impression of detail-reproducing test block taken using addition-type silicones (Correct VPS ; J/P, Exafine ; G.C., Express ; 3M, Extrude ; Kerr, Provil ; Bayer, Reprosil ; Dentsply) with the intervals of 0, 15, 30, 45, 60, 90 and 120 minutes. Gypsum model was removed from the impressions and the number of bubbles on the surface of casts was counted after 30 min. Ordinal numbers were given to the ranges of the number of bubbles like this, Score 0 ; 0, 1 ; 1∼10, 2 ; 11∼30, 3 ; 31∼60, 4 ; 61∼100, 5 ; 101∼200, 6 ; 201∼400, 7 ; 401 or more. There was no bubble in Correct VPS impression poured immediately in MG dental stone and Extrude impression poured immediately in New Fujirock, New Plastone, and MG dental stone. Significant bubbles were appeared in Provil until 15 minutes(Score 1∼3), Reprosil until 30 minutes(Score 1∼2), and Express until 45 minutes(Score 1∼2) in all gypsum models(p<0.05). Express impression poured in Suprastone(Score 2) and New Plastone(Score 4) had bubbles until 120 minutes(p<0.05). On the basis of this study it can be concluded that not only hydrogen release but also compatibility with gypsum should be considered when using addition silicones.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

'선도 추격'에서 '동반 추격'으로의 전환을 위한 서비스 산업의 역할과 전략 : 한일 생산성 비교의 시사

이근,정무섭,김윤지 韓國東北亞經濟學會 2008 동북아경제연구 Vol.20 No.2

The Korean economy has grown very fast over the last decades, but it was an uneven catch-up led by a big business and manufacturing. Now it is time for co-catchup led by both manufacturing and services. This paper analyzes the weight and productivity of the service sector in Korea and suggests for policies for its improvement in productivity. The service sector in Korea is featured by low and declining productivity (both TFP and labor productivity), and a big trade deficits, which is in contrast to the trade surplus in manufacturing. This performance is worse, compared with the situation in Japan. For example, the ratio of labor productivity in service to that in manufacturing is only 14%, compared to 46% in Japan. Causes for the low performance in service include too much regulation and lack of competition due to the closed market. Thus, measures to boost up productivity in service include deregulation and market opening, which would open up the opportunity for learning from foreign companies. Industrial policy should also change from input-oriented one to network-oriented one emphasizing the unity of commodities and services.

初乳의 分泌期間中의 成分變化 및 保存性에 관한 硏究

李鳳求,金相根,李晩徽,金武剛 충남대학교 수의과대학 동물의과학연구소 1995 動物醫科學硏究誌 Vol.3 No.-

The study was carried out to investigate the charges of hourly and daily components and preservation of colostrum produced 1st through 7th day after parturition of Holstein cows. The results obtained were summarized as follows : 1. The specific gravity in colostrum was 1.032-1.057 from 1 to 24 hrs after parturition and then showed slightly higher than normal milk. The pH and titerable acidity were 6.43 and 0.170% at 1 hrs after parturition respectively and thereater gradually increased. 2. The solids not-fat, fat and protein of colostrum were 16.24%, 6.60% and 14.20% at 1hrs after parturition respectively, and then showed markedly higher than normal milk. 3. The solids not-fat, fat and protein of colostrum were 9.02%, 6.66% and 3.92% at day 1 postpartum respectively and thereafter gradually decreased. But milk lactose ranged from 2.47% to 4.76% at day 1-7 postpartum and thereafter gradually increased. 4. The F, Mg and Fe of colostrum were 0.244%, 0.064% and 0.430% at day 1 postpartum respectively. The Ca and Na were 0.262% and 0.074% at day 1 postpartum and then showed markedly higher than normal milk and thereafter gradually decreased. 5. The pH from 1st through 5th days of milking was decreased from 6.4 to 5.3. The number of common bacteria reached a peak levels of 1×10^7.5/ml after 3-7 days and then slightly decreased. The number of coli from group reached a peak levels of 1×10^8/ml after 3 days and thereafter rapidly decreased to 10^3/ml after 20 days. 6. The number of common bacteria of colostrum added 0.5, 1.0 and 2.0% of propionic acid and acetic acid at 20℃ were inhibited from 1 to 20 days in addition of 0.5%-2% propionic acid and acetic acid. The number of coli form group was retarded from 3 to 7 days addition of 1.0%-2.0% propionic acid and acetic acid. The addition of propionic acid and acetic acid to colostrum were effective in retarding the growth of bacteria than acetic acid.

오골계, 토종계 및 산란계의 卵黃, 卵白 및 卵殼중 無機質 含量에 관한 硏究

李明憲,李鍾鎭,金相根,金武剛,韓成郁 충남대학교 수의과대학 동물의과학연구소 1995 動物醫科學硏究誌 Vol.3 No.-

This study was to assayed 12 trace minerals of Ca, P, Cu, Fe, K, Mg, Mn, Na, Ni, Zn, Al and B components of Korean native ogol, Korean native fowls and laying hen's egg yolk, albumen and egg shell by with Inductively Coupled Argon Plasma(ICAP). The results summarized as follows: 1. The levels of P, K, Mg, Na components of Korean native ogol and Korean native fowl's egg yolk and albumen were high components than laying hens. 2. The levels of Ca, P, Fe, Na, Zn components of Korean native fowl's egg yolk were higher than Korean native ogol and laying hens. Particularly the levels of Ca, Na components showed signicantly high. But, the levels of Cu components of Korean native ogol's egg yolk was higher than Korean native fowl's and laying hens. 3. The levels of Ca, P, Mg components of Korean native fowl's albumen were high components. And the level of Cu, Fe, K, Na components of Korean native ogol's albumen were very high. 4. The levels of Ca, P, Na, P, K constituents of Korean native ogol and Korean native fowl's egg shall were high.

COX 모델을 이용한 생존자료분석에서 Proportionality 가정 검정의 의의

이무송,유근영,노동영,최국진 대한암학회 1991 Cancer Research and Treatment Vol.23 No.4

절수에 의한 mongolian gerbil의 체중 변화에 관한 연구

이경열,송치원,김무강,조성환,류시윤,김상근,박배근 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

Recently, the mongolian gerbils have been used in neurology and the study of water metabolism because of their easy onset of epileptic seizure and typical resistance to water deprivation. The sebaceous glands which are under the control of the gonadal hrmones are differently developed from the other laboratory animals. However the physiological data on the changes of body weight following water deprivation in mongolian gerbils is not available until now. In order to investigate the effect of the water deprivation on the body weight, the animals were deprived of water for 15 days. The body weights were measured daily by the torsion balance. The mean, the standard deviation, the standard error and the coefficient of variance of the body weights were calculated. The correlation was examined. The potential regression equation was y = 61.5458 - 2.0533 * x + 0.0487 * x^2. The regression coefficient was 0.993. The results obtained were as follows : 1. The body weights of the mongolian gerbils were continuously decrased from the 1st day to the 15th day after the water deprivation. 2. The mean body weight on the water deprivation was 63.0±7.00g and that at the 15th day was 41.4 ± 5.42g. 3. The coefficients of the variance showed the highest (13.09) at the 15th day and the lowest (10.10) at the 10th day. the coefficients of the variance kept decreasing until the 10th day and thereafter gradually increased until the 15th day. 4. The changing rate of the body weight kept continuously decreasing from the 1st day to the 15th day showing the daily loss of 1.0 - 3.3%. 5.The deviations (M - QBW) between the measured values (m) and the theorical values (QBW) using the regression equation showed the highest (1.494) at the 1st day and the lowest (0.053) at the 13th day. 6. The sum of the devitions was 0.179 and that of the deviation square was 1.15. The sum of the deviation rates between the mesaured body weights and the theorical ones was 0.484. 7. The daily body weight loss showed the highest at the 1st day by 2.053g and the lowest at the 15th day by 0.591g. 8. The specific body weight changing rates which were the rate of the body weight changing velocity to the changed body weight were decreased from 0.033% at the 1st day to 0.014% at the 15th day.

생체분해성 안과제형의 안구내흡수정도와 안독성

민병무,김용백,박근성,송규상,양준묵,이성복,조항진,길숙종,김승영,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

An improved retinal tack can be used to fix the retina in complicated retinal detachment and proliferative vitreoretinopathy. We used the retinal tack made by biodegradable polyglycolic acid, polylactic acid and copolymers. The tacks with polyglycolic acid were placed in the retina the right eyes of 10 rabbits as group 1, with polylactic-polyglycolic acid copolymers as group 2 in each left eyes. We examined the absorption rates and degree of intraocular inflammation at 1 day, 1, 2, 4, and 8 weeks and compared both eyes. The tacks were absorbed with time in both eyes, but more rapid in copolymers. And there was no inflammation in both eyes. Now, this study will be a base on the drug delivery system in intraocular pharmacological and surgical management.

干拓地에서 潮位와 地下水位와의 關係에 對하여

權武男,李根厚,金哲會 慶尙大學校 1975 論文集 Vol.14 No.-

The relation between tide level and ground water level in reclaimed land is one of important imformations to make the successful agriculture in reclaimed land and water resources development. To clarify this relationship, an investigation was made at the newly reclaimed land located in Gyeong-nam province. Obtained results were as follows: 1. The fluctuation of tide level affected significantly (r=0.468*∼0.670**) the ground water level variation in reclaimed land. 2. The nearer to shore line, the greater the effect of tidal fluctuation on ground water level. It was found that no significant effect of tidal fluctuation on ground water level existed beyond the range of 2km from shore line. 3. The average ground water level during the rising interval of tidal curve was higher than the average ground water level during the falling interval of tidal curve. 4. The magnitude of ground water level variation curve was one half of the magnitude of tidal curve.

Rat의 복강에 삽입한 Fluorouracil-Polyglycolic acid 제형의 Fluorouracil 용출에 관한 연구

노승무,정경수,오정연,김진향,양준묵,강대영,송규상,최정목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

A common form of relapse in adenocarcinoma of the stomach is intraperitoneal dissemination, in fact, among gastric adenocarcinoma patients who have undergone surgery intended to cure, approximately 50% of the patients develope initial recurrence in the peritoneal cavity regardless of the anatomic site of the primary tumor within the stomach. The efficacy of systemic postoperative chemotherapy to prevent peritoneal recurrence of gastrric adcnocarcinoma is not satisfactory. There is still a great need for improved therapeutic strategies on the disseminated microscopic disease and small miliary nodules remaining on the peritoneal surface or lymphatics after operation. The authers have made fluorouracil-polyglycolic acid composite disks(Fu-PGA disks) with fluorouracil and biodegradable polymer: polyglycolic acid for more effective intraperitoneal chemotherapy. We inserted the Fu-PGA disk(s) in the peritoneal cavity of rat and pharmacokinetic study was performed to measure fluorouracil concentration in the peritoneal fluid, plasma, liver, kidney and heart tissue at 24 hour, 72 hour and 168 hour after insertion of Fu-PGA disk(s). Myelosuppressive action of this composite also was determined following its administration. The data of this study suggested that Fu-PGA composite will be a new device releasing drugs in a controlled manner and having targetability to peritoneum, and this device will be improving the efficacy of intraperitoneal chemotherapy for gastric adenocarcinoma.