연약한 점성토 지반의 지지력 결정에 관한 연구

안종필,박상범,김규덕 朝鮮大學校 建設技術硏究所 2004 建設技術硏究 Vol.24 No.2

To find out the variation of bearing capacity due to the plasticity of soils in case of working the unsymmetrical surcharge of ML, CL, and CH, the existing theoretic expression were investigated and were compared with a series of test results The critical surcharge of soft soils was found as q_(cr)=4.22C_(u) in ML, which is slightly larger than the existing expression, but similar to Darragh's expression. The critical surcharge in CL was found as q_(cr)=3.21C_(u), which is the value between JHI and Jaky and in CH was found as qcr=2.60C_(u), which is a the value between Tachebotarioff and Meyerhof. The ultimate bearing capacity of soft soils was found as q_(uIt) = 11.19C_(u) in ML, which was significantly larger than the existing expression. The ultimate bearing capacity of CL was found as q_(ult)=8.41C_(u), which was slightly bigger than the existing expression, but is close to Meyerhof's expression. The ultimate bearing capacity in CH was found as q_(uIt) =4.73C_(u), which is similar to Parndtl's expression.

한국인에서 DXS7132 유전좌와 GATA31D10 유전좌의 다형성에 관한 연구

안종성,장영길,이숭덕,신창호,이윤성,이정빈 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

The validation study for two STR loci on X-chromosome, DXS7132 and GATA31D10, was done including allelic distribution and frequency of each allele to use these results for individual identification and paternity testing. For 496 unrelated Koreans, above two STR loci were amplified simultaneously using duplex PCR amplification method. The amplified products were analyzed by polyarylamide gel electrophoresis followed by silver staining. In male DXS7132 locus revealed 7 different alleles ranging from 276bp to 300bp. The largest allele was consisted of 14 repetition of [TCTA] unit and took 0.3417. The allele 15 followed next as 0.3165 and allele 13 as 0.1726. In female general distribution was same except one allele, allele 18 was found additionally. The heterozygosity was 0.7706 and 23 different genotypes were found. Polymorphism information content(PIC) was 0.727. Two cases of mutation were noted in DXS7132 locus In both male and femal 7 different alleles were noted in GATA31D10 locus and the alleles ranged from 195bp to 231bp. The allele 15(199bp) took the majority of all as 0.825. The other alleles showed rather relatively low frequency. The heterozygosity was 0.2385 and 11 different genotypes were found. PIC was 0.2521, and no mutation was noted in GATA31D10 locus. Considering these two loci together, 22 different halpotype were noted.

건설산업에서 ISO 9000의 적용방안 연구

안종필,박상범,유덕찬 朝鮮大學校 建設技術硏究所 2001 建設技術硏究 Vol.21 No.1

This study conducts the questionnaire with 320 employees who work in the construction field and head office of 80 construction companies which acquired ISO 9000 quality systems with a view to complement the problems from the application of ISO quality system to the construction industry. Acquirement of ISO certificate with the formal quality system or its formal post management adds to unnecessary tasks and will be a cause to deteriorate the progression of key projects on the business management. Therefore, when ISO 9000 quality systems is made in consideration of the scale, business capacity and customers' requirements and are suitable to the actual affairs and systematized system is established, execution quality will be improved and it will result in the decisive effects for construction field control.

전기 치수 검사 시 역치 자극 이후 과용(過用) 자극 시간의 측정

남기창,안선희,김수찬,김덕원,이승종 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.3

Use of electric pulp testing elicits painful response in vital teeth. In this study, we examined the excessive time from pain feeling to stimulation disconnection in clinical situation. D626D (Parkell Inc., USA.) scan type electric pulp tester was used in total of 23 young healthy individuals. Each of the right central incisors and first premolars were used as testing teeth. Stimulation disconnection was achieved by EMG in anterior belly of digastric muscle, finger span, and voice and the excessive stimulation time over the sensory threshold was recorded. As a result, we found that the short responses before the stimulation disconnection appeared following order: EMG, finger span, and voice. The EMG disconnection is suggested to be used to reduce the excessive stimulus time in electric pulp testing.

154kV용 활선 안전 경보기 개발에 관한 연구

정민규,조현광,우종수,안창회,서영석,김응태,박창기,오세득 영남대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.28 No.1

In this report we developed a high voltage alarm for the safety of workers who check and repair the 154kV power line. This high voltage alarm we developed is attached on workers' helmet and alarms automatically in order to let workers know when workers work over the safety distance near 154kV power line. Until now the exact safety distance hasn't been regulated and high voltage alarm we've been using was for the range of 6∼22.9kV power line. We fabricated this high voltage alarm on the basis of electric density and actual measurement of power line. The experimental result was that high voltage alarm at 66kV power line alarmed near 90cm, at 154kV power line alarmed near 160cm from the line. Accordingly, we developed the new high voltage alarm which is operated in the range of 66∼154kV power line.

백서 혈관평활근 세포에서 α-Lipoic acid가 PAI-1 발현, 세포의 증식, 주유능 및 신생내막 형성억제에 미치는 효과

신동우,이동욱,이상준,김혜순,강효경,안종덕,이인규 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.6

연구배경:당뇨병의 혈관 합병증의 발생에 있어서 산화스트레스는 중요한 역할을 하는 것으로 알려져 있다. 혈관 평활근세포에서 고혈당은 안지오텐신Ⅱ와 더불어 활성산소족(ROS)을 증가시키며, 산화스트레스에 민감한 전사인자들을 활성화시켜 동맥경화증을 유발하는 것으로 알려져 있다. 이에 저자들은 항산화제로 알려진 알파­리포산이 혈관 평활근세포의 증식속도와 이주에 미치는 영향과 PAI­1발현에 미치는 영향을 조사하였고 이와 동시에 백서의 혈관 손상 모델을 이용하여 알파­리포산이 신생내막 증식을 억제시킬 수 있는지를 알아보았다. 방법:In vitro 실험은 백서의 대동맥 평활근세포를 고농도의 포도당(22mM)과 100nM의 안지오텐신Ⅱ로 4시간 배양하였다. 알파­리포산을 처리 후, PAI­1 mRNA의 발현을 보기 위해 노던 블롯을 시행하였고 평활근세포의 유주능과 증식속도에 미치는 영향을 보기 위해 성장속도의 유주능 분석을 시행하였다. 또한 평활근세포의 유주능에 NF­μB 경로가 미치는 영향을 보기 위해 겔 지연 분석과 NF­μB 보고 유전자 분석을 시행하였다. In vivo 실험으로 백서의 혈관손상 모델을 이용하여 알파­리포산 처리 후 혈관의 신생내막 두께를 비교하였다. 결과:In vitro 실험에서 고농도 포도당과 안지오텐신Ⅱ에 의해 유도된 PAI­1 mRNA 발현증가는 알파­리포산 처리에 의하여 용량에 비례하여 억제되었다(p<0.05). 알파­리포산 처리로 혈관 평활근세포의 유주능은 유의하게 억제되었으나(p<0.01),증식속도는 유의하게 억제되지 않았다. 또한 알파­리포산 처리로 NF­μB 발현도 유의하게 억제되었다(p<0.01). In vivo 실험에서 알파­리포산을 주입한 군에서 혈관손상에 의한 신생내막의 증식이 유의하게 억제되는 것을 보여주었다(p<0.01). 결론:알파­리포산은 백서의 대동맥 평활근 세포의 증식속도는 억제하지 못했으나 유주능은 유의하게 억제하였으며, 혈관 손상 모델에서 신생 내막 증식도 유의하게 억제함을 확인할 수 있었다. 이러한 작용은 알파­리포산에 의한 NF­μB 경로의 억제와 연관이 있는 것으로 사료된다. Background : Exposure to large amounts of glucose causes a characteristic dysfunction and morphologic changes of the endothelium by an increased production of reactive oxygen species(ROS) in diabetes. The plasminogen activator inhibitor-1(PAI-1), which modulates fibrinolysis and cell migration may influence proteolysis and neointimal formation in vascular smooth muscle cells(VSMC). Antioxidants have been proposed to inhibit multiple proatherogenic events. This study investigated the effect of α-lipoic acid on PAI-1 expression and VSMC proliferation and migration both in vivo and in vitro. Methods : In the in vitro study, cultured rat aortic smooth muscle cells(RASMC) were incubated in a medium containing high glucose (22 mM) and 100 nM angiotensin Ⅱ for 4 hour. After α-lipoic acidtreatment, a -migration and growth assay of the RASMC, and a gelmobility shift assay and reportergene analysis for nuclear factor- иB(NF- иB) and northern blot analysis for PAI-1 were performed. In the in vivo study, the effect of α-lipoic acid on neointimal hyperplasia in a rat carotid balloon injury model was evaluated. Results : RASMC migration was inhibited significantly by α-lipoic acid (p<0.01), but their prolife ration was not inhibited. The NF-иB DNA binding activity and NF-иB promoter activity was inhibited by α-lipoic acid significantly (p<0.01). α-lipoic acid inhibited PAI-1 mRNA expression by high glucose and angiotensin Ⅱ in dose dependent manner (p<0.05). In the rat carotid artery balloon injury model, neointimal formation was reduced by α-lipoic acid treatment in a dose dependent manner significantly (p<0.01). Conclusion : α-lipoic acid suppresses migration, but not prolife ration in RASMC. α-lipoic acid also reduce neointima formation in a rat carotid balloon injured model. This effect might be related to the blocking of NF-иB which increase the expression of the genes associated with atherosclerosis including TNF-α, IL-1, IL-6, endothelin-1, MCP-1, VCAM-1, ICAM-1, E-selectin, tissue factor(J Kor Diabetes Asso 25:446~459, 2001).

Comparison of Photosynthesis between Treatment and Non-treatment of Lime Bordeaux Mixture in 3 Year Old Root in Panax ginseng C. A. Meyer

Ahn, Deok-Jong,Jung, Won-Kwon,Choi, Jin-Kook,Jang, Myeong-Hwan,Kwon, Tae-Ryong,Shin, Yeon-Hwa,Lee, Sang-Chul The Plant Resources Society of Korea 2013 한국자원식물학회지 Vol.26 No.3

Korean ginseng has been used for thousands of years as an important medicinal plant. Lime-Bordeaux mixture (LBM) was made with copper sulfate and quicklime, which was sprayed instead of pesticides in ginseng field. Net photosynthesis ($P_N$) was compared between Treatment and Non-treatment of LBM in 3 Year Old Ginseng. $P_N$ in control plot recorded $2.94{\mu}mol\;(CO_2)\;m^{-2}s^{-1}$ at the first day of experiment, which was similar until the last day of experiment. However, The $P_N$ in LBM recorded $2.23{\mu}mol\;(CO_2)\;m^{-2}s^{-1}$, which was lower than that in control plot. As time goes by, The $P_N$ in LBM was gradually increased up to $3.21{\mu}mol\;(CO_2)\;m^{-2}s^{-1}$ and finally, it was similar with that in control plot at 7th day as a $3.20{\mu}mol\;(CO_2)\;m^{-2}s^{-1})$.

Phytic Acid and Mineral Composition of Rice Cultivars Grown at Southern Part of Korea

Ahn Deok-Jong,Won Jong-geun,Park Sang-go,Park So-Deuk,Lee Sang-Chul 한국작물학회 2005 한국작물학회 학술발표대회 논문집 Vol.2005 No.-

신뢰성이론에 의한 널말뚝벽의 안정해석에 관한 연구

안종필(Ahn Jong-Pil),김규덕(Kim Gyu-Deok),김용덕(Kim Yong-Deok) 대한토목학회 2009 대한토목학회 학술대회 Vol.2009 No.10

3년생 인삼포에서 석회보르도액 연속살포가 토양이화학성 및 구리함량변화에 미치는 영향

안덕종(Deok-Jong Ahn),권태룡(Tae-Ryong Kwon),최진국(Jin-Kook Choi),장명환(Myeong-Hwan Jang),정원권(Won-Kwon Jung) 한국약용작물학회 2012 한국약용작물학회 학술대회논문집 Vol.2012 No.1