오리 鼻腔 및 鼻粘膜上皮의 計測에 관한 硏究

金世仁,金武剛,申台均,金弘善,柳時潤,李永浩 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

The area of the various epithelial types linging the nasal navity of each six number in 1-week-old and 10-week-old adult ducks has been made for the light microscopic research. Transverse sections of 10 microns thick in each specimen were made continuously from the anterior end of nostril to the posterior end of pharyngeal inlet and specimen samples were selected at 0.13mm(1-week-old) and 0.17mm(10-week-old) intervals from the anterior end of the nasal cavity to the posterior end of pharyngeal inlet. The results obtained from research were summarized as follows. 1. The nasal cavity is lined with stratified squamous, respiratory and olfactory epithelium. The thickness of stratified squamous, respiratory and olfactory epithelium is 10-100㎛, 8-75㎛ and 50㎛ respectively in 1-week-old ducks, and 25-175㎛, 20-125㎛ and 66㎛ respectively in 10-week-old ducks. 2. The unilateral volumes of the nasal cavity in 1-week-old and 10-week-old ducks were 21.73±2.64㎟, 1,692.44±171.57㎟ respectively. 3. The total unilateral surface areas of the nasal cavity in 1-week-old and 10-week-old ducks were 70.44±4.92㎟, 1,772.45±94.10㎟ respectively. 4. Each area of the stratified squamous epithelium, respiratory epithelium and olfactory epithelium in unilateral nasal cavity is 14.82±1.85㎟ (21.1%), 46.86±3.20㎟ (66.5%) and 8.76±0.40㎟ (12.4%) in the 1-week-old ducks, and 348.23±40.02㎟ (19.7%), 1,282.31±47.03㎟ (72.3%) and 141.90±12.43㎟ (8.0%) in the 10-week-old ducks. Ducks are assumed as a microsmatic animals by the composition of the lining epithelium of the nasal cavity in ducks.

國家意識의 實態와 그 對策 : 국기, 애국가 및 국민교육헌장의 보급을 중심으로

李建衡,盧禎埴,成炳卓,姜萬石,朴泰岩,朴仁熙,金漢植 대구교육대학교 1971 論文集 Vol.7 No.-

國旗의 常備現況은 總體的으로 보아 低調한 實態에 있다. 全體 標集者의 86.8%가 國旗를 備置하고 있다는 反應을 보였으나, 이 數置가 보이는 內容은 區區하다. 卽 깃발과 그 附帶品一切를 完備한 家庭은 全體의 42.5%에 不過하고 깃발만을 備置한 家庭이 20.4%, 函까지를 갖춘 家庭이 45.8%로서 約 半數의 家庭이 適當한 場所에 깃발을 保管하고 揭揚時에는 적의한 막대기로 代用할뿐만 아니라 깃발조차 없는 家庭이 約 15%에 이르는 셈이다. 最少限 깃발만이라도 갖춘 家庭을 地域別로 보았을 때 中都市의 96%, 農村의 90%만이 全體의 86.6%를 上廻하고 있고 漁村 79.6%가 特히 低調함은 注目할 일이다. 그리고 附帶品의 具備狀況이나保管도 中都市가 比較的 充實하고 漁村이 低調한 傾向을 보이고 있으며 意外로 農村보다도 大都市가 모든 面에서 不實함도 注目할 일이다. 國旗의 保管이나 揭揚은 主로 젊은 學生層에서 擔當하고 있다. 이러한 傾向은 農·山村일수록 年令이 낮아지고 中都市와 大都市는 비슷하게 年令이 높아지는데 이로 미루어 高令層의 啓蒙이 要請된다고 하겠다. 國慶日의 國旗揭揚狀況는 質問紙에 依한 應答 結果는 約 70%이나 實際 揭揚은 約 35%의 低調한 것이어서 깃발조차 갖고 있지않는 約 15%를 감안하더라도 言行이 一致하지 않는 一面을 엿볼 수 있다. 特히 中都市(37%) 大都市(49.2%) 農村(37.8%)과 對比할 때 前述한 깃발 備置狀況과 逆現象을 보인 都市人의 覺醒을 促求하지 않을 수 없다. 國旗揭揚法의 正確性 與否는 問題가 될 것이나, 大部分 알고 있으면서도 關心과 誠意가 없어서 國慶日에 國旗를 揭揚하지 않는다고 反應한 데 對한 積極的인 對策이 要望되며 特히 國慶日을 모르기 때문에 憩揚하지 않는다은 것을 1順位로 反應한 山村을 留意해야 겠다. 國旗의 뜻을 잘 모른는 國民이 大部分이고 이러한 現象은 意外로 靑年層일수록 더한 것이 豫想과는 相反되고 있다. 國旗의 制定由來나 그 國家象徵性을 認識하지 못하는 傾向 亦是 같은 現象을 보이고 있다. 다만 由來나 象徵性에 對한 認識에 關한 限 都市民과 漁村民이 比較的 높고, 農村과 山村民이 相對的으로 낮다. 農·山村에 比한 漁村, 大都市에 比한 中都市의 住民이 갖는 相對的으로 높은 認識度는 東海岸民의 安保意識과 中都市人의 等質性 및 國家施策의 浸透 容易性에 緣由하는 것이라고 생각된다. 그리고 우리 國民은 國旗의 뜻을 모른는 者가 3分의 1에 該當하고 國旗에 대한 公式的 敎育을 받지 못한 사람도 3分의 1에 이르며 國旗를 그릴 수 없는 사람이 半以上이나 된다. 國旗에 關한 諸般 認識度는 男子보다 女子가, 年令別로는 老令層이, 生活程度는 낮을수록 低調한 것을 알 수 있고, 全體 國民의 우리 國旗에 對한 滿足度에는 유감이 없음을 보여주고 있다. 愛國歌의 普及 實態는 過히 不振한 便은 아닌 것 같다. 80.9%의 國民이 적어도 愛國歌의 1절以上을 부를 수 있고 愛國歌가 들려올 때 約 18.6%의 國民을 除外한 大多數 國民이 차려姿勢 또는 경건한 態度를 가질뿐만 아니라 愛國歌의 普及强化를 所望하는 反應이 78.1%나 되었다는 것이 이를 立證하고 있다. 그리고 地域的으로는 大都市에 比해 中都市가 農·山村에 比해 漁村이 보다 健全함을 보여주고 있다. 그러나 部分的으로는 問題가 없는 것도 아니다. 愛國歌를 1절도 못외우는 18.4%, 愛國歌가 들려와도 無關心한 18.6%의 國民이 있고, 이러한 反應度는 愛國歌 부르기 敎育을 받은 적이 없는 33.2%의 國民, 愛國歌 解說敎育을 받은 적이 없는 47.8%의 國民 및 한해에 한번도 愛國歌를 부를 機會가 없는 36.0%의 國民이 있다는 事實과 有關하리라고 생각된다. 上述한 問題點은 地域的으로는 都市보다는 農·山·漁村이, 特히 農村에 比해 農·山村이, 學歷 및 年令上으로는 文盲者 및 國·漢文 解讀者를 그 속에 간직하고 있는老令層에, 男子보다는 女子가, 또한 生活程度는 낮을수록 尤甚하다는 것을 指摘할 수가 있다. 全體的으로 보아서는 中都市의 實積이 大都市 및 餘他地域보다 良好하고 豫想한대로 農·山村에 比해 漁村이 두드러진 特徵을 보이고 있는 點이다. 그리고 愛國歌의 普及 및 그 敎育에 있어서는 資料 通計上으로는 그 어떤 經路보다도 學校敎育의 充實이 가장 效果的이었다는 것을 보여주고 있으나 愛國歌의 普及强化策에 對한 反應을 中心으로 본다면 山·漁村을 除外한 모든 地域이 新聞 放送 等의 報道機關을 通한 普及을 希望하고 있다. 이는 이미 指摘한 老年層, 文盲者, 國漢文 解讀者, 및 家庭主婦인 女子를 相對로 한 境遇에 異論이 있을 수 없겠고, 報道機關의 普及率이 낮은 山村이 學生啓蒙運動을 그리고 安保意識이 强한 漁民이 地域別 成人敎育을 希望한다고 보아 無妨할 것이다. 그리고 劇場 演藝物을 通한 普及은 效果가 적을 것임이 나타났고 그 밖에는 妙案이 없는 것으로 反應되었다. 그리고 愛國歌의 普及强化를 所望하는 意志는 强하다고 할 수 있는 것은 이미 指摘하였거니와 이 境遇에는 規制的인 方法보다도 自律的인 方法 例컨대 報道機關을 通한 宣傳啓蒙이나 山·漁村을 對象으로 한 學生啓蒙運動 또는 里動單位의 自體啓蒙을 希望하고 있음을 特記해 둔다. 國民敎育憲章 普及實態의 全體的인 傾向은 公布事實마저도 모른다 24.0%, 憲章冊子를 가지지 않았다 約 30%, 制定의 理由를 모른다 30% 等으로 보아 制定公布된지 3年이란 時間的 經過에 비추어 豫想外로 低調하다 할 수 있으며 地域別로 보면 制定事實의 知悉, 內容理解 分析努力, 暗記努力, 普及施策 贊成面에서 中都市가 大都市보다 理解度가 높게 나타났으며 漁村이 現實與件上 國家意識이 높으리라는 豫想은 立證되지 않았으며, 山村은 豫想한대로 普及狀態가 極히 不振하였다. 性別로는 男子의 理解度가 높고, 年令別로는 年令이 낮을수록 學歷은 높을수록 生活程度는 높을수록 普及實態나 理解度가 높아지고 있다. 다만 制定理由의 知悉面이나 分析經驗 普及施策에 對한 贊同面에서 大學卒業 以上의 學歷者가 高等學校 卒業者보다 낮게 나타난 點은 異彩로운 現象이다. 職業別에 있어서는 大體로 公務員, 商·써비스業, 無職, 農業의 順으로 意識이 높다. 憲章公布事實을 알게 된 經路나 普及을 爲한 效果的인 施策의 選擇狀況을 보면 報道機關이 가장 效果的이며 學校敎育의 影響이 意外로 低調함을 發見할 수 있다. 普及施策中 學生을 通한 啓蒙運動에 對한 共鳴度도 낮고, 劇場 및 演藝機關을 通한 普及은 큰 支持를 받지 못하고 있음이 發見되었다. 暗記動機는 自發的인 境遇가 29.2%에 不過화고, 憲章에 對한 一般의 關心度가 낮으며 普及運動의 反對理由로는 "形式에 흘러 實效性이 없다"가 24.2%로 가장 높다. 以上을 綜合해 볼 때 國旗, 愛國歌, 및 國民敎育憲章 할 것 없이 그 普及 및 認識度가 豫想外로 低調함을 알 수 있다. 愛國歌에 關한 限 80.9%의 國民이 1절 以上의 愛國歌를 부를 수 있는 바 他 2者에 比해 相對的으로 良好한 便이나 公式集會의 慣例 탓으로 4절까지를 모두 외우는 者는 極히 不振하다. 要컨대 三者가 모두 敎育 또는 啓蒙이 不實하였음이 立證되었으며 特히 知識水準이 낮은 老年層과 性別로는 女子, 地域的으로는 山村, 農村, 漁村의 順으로 不振하였고 豫想外로 大都市 및 大學卒業者가 低調하였음도 發見되었다. 그리고 愛國歌에 關한 限 學校敎育으 效果가 斷然 越等한 反面 國民敎育憲章의 普及 및 認識은 學校敎育보다도 報道機關의 啓蒙이 奏效하였음이 發見되었다. 그리고 國旗의 國家象徵性에 關한 認識은 光復後의 學校敎育을 받은 靑少年層이 보다 健全하여 日帝下에서 靑壯年期를 보낸 壯·老年層이 意外로 低調한 傾向을 보여주고 있다. The research in this report was done to discover the reality of the korean National Consciousness. By this we mean an awareness of the National flag, the National Anthem, and the Charter of National Education in Korea. Also since threre appears to be a lack of awareness in certain areas we have attempted to propose adequate measures to imporve these conditions. Methods and materials used for this study are as follows: the method was of Random Sampling in which we selected randomly 900 men and women living in a city, a town, farm areas, remote areas, and sea-side areas. The materials was an interview form called "the schedule" which consisted of 46 items. From the data received we reached the conclusion that knowledge about the National Flag, the National Anthem, and the Charter of National Education in Korea was generally poor. This trend appeared more in the farm area, remote area, and seaside area then in the city and town; more in women than in men; more in the old than in the young, more in those of lower academic careers and lower economic levels than of their counterparts with better careers and living levels. From the above conclusions we propose that the community schools and the mass communication system in korea strive actively to increase the instruction of these people in order to improve the national consciousness of the above mentioned people.

Enhanced activation of NAD(P)H: quinone oxidoreductase 1 attenuates spontaneous hypertension by improvement of endothelial nitric oxide synthase coupling via tumor suppressor kinase liver kinase B1/adenosine 5&vprime;-monophosphate-activated protein kina

Kim, Yong-Hoon,Hwang, Jung Hwan,Kim, Kyung-Shim,Noh, Jung-Ran,Gang, Gil-Tae,Oh, Won Keun,Jeong, Kyeong-Hoon,Kwak, Tae Hwan,Choi, Hueng-Sik,Lee, In-Kyu,Lee, Chul-Ho Wolters Kluwer Health | Lippincott Williams Wilkin 2014 Journal of Hypertension Vol.32 No.2

AIMS:: Guanosine 5&vprime;-triphosphate cyclohydrolase-1 (GTPCH-1) is a rate-limiting enzyme in de-novo synthesis of tetrahydrobiopterin (BH4), an essential cofactor for endothelial nitric oxide synthase (eNOS) coupling. Adenosine 5&vprime;-monophosphate-activated protein kinase (AMPK) is crucial for GTPCH-1 preservation, and tumor suppressor kinase liver kinase B1 (LKB1), an upstream kinase of AMPK, is activated by NAD-dependent class III histone deacetylase sirtuin 1 (SIRT1)-mediated deacetylation. &bgr;-Lapachone has been shown to increase cellular NAD/NADH ratio via NAD(P)H:quinone oxidoreductase 1 (NQO1) activation. In this study, we have evaluated whether &bgr;-lapachone-induced NQO1 activation modulates blood pressure (BP) through preservation of GTPCH-1 in a hypertensive animal model. METHODS AND RESULTS:: Spontaneously hypertensive rats (SHRs), primary aortic endothelial cells, and endothelial cell line were used to investigate the hypotensive effect of &bgr;-lapachone and its action mechanism. &bgr;-Lapachone treatment dramatically lowered BP and vascular tension in SHRs and induced eNOS activation in endothelial cells. Consistent with these effects, &bgr;-lapachone treatment also elevated levels of both aortic cGMP and plasma nitric oxide in SHRs. Meanwhile, &bgr;-lapachone-treated SHRs showed significantly increased levels of aortic NAD, LKB1 deacetylation, and AMPK Thr phosphorylation followed by increased GTPCH-1 and tetrahydrobiopterin/dihydrobiopterin ratio. In-vitro study revealed that AMPK inhibition by overexpression of dominant-negative AMPK nearly abolished GTPCH-1 protein conservation. Enhanced LKB1 deacetylation and AMPK activation were also elicited by &bgr;-lapachone in endothelial cells. However, inhibition of LKB1 deacetylation by blocking of NQO1 or SIRT1 blunted AMPK activation by &bgr;-lapachone. CONCLUSION:: This is the first study demonstrating that eNOS coupling can be regulated by NQO1 activation via LKB1/AMPK/GTPCH-1 modulation, which is possibly correlated with relieving hypertension. These findings provide strong evidence to suggest that NQO1 might be a new therapeutic target for hypertension.

단면 CT 영상을 이용한 무치악 하악 대구치부 잔존골의 형태 분석

이설미,허경회,이원진,허민석,이삼선,강태인,최순철 대한구강악안면방사선학회 2007 Imaging Science in Dentistry Vol.37 No.3

Purpose : The purpose of this study was to evaluate the morphologic features of posterior edentulous mandible for Korean patients using cross-sectional CT images. Materials and Methods : Computed tomographic cross-sectional views taken in 2004 and 2005 at Seoul National University Dental Hospital were analyzed by an oral and maxillofacial radiologist. Four indices were measured to meet the purpose of this study: 1) the horizontal distance between the alveolar crest and mandibular canal (Type), 2) the angle of the mandibular long axis (Angle), 3) the bucco-lingual location of mandibular canal, and 4) the depth of the submandibular fossa. The averages and standard deviations of the measurements were compared according to the location (the first and second molar area) and sex of the patients. Results : Statistically significant difference was found in Type, Angle, and submandibular fossa depth between the first and second molar area (P<0.05). However, there was no significant difference between men and women in any of the measured indices. Most of the mandibular canals were located in lingual side of posterior mandible. Conclusion : More care should be taken when an implant is installed on the mandibular second molar area.

SHIELDING ANALYSIS OF DUAL PURPOSE CASKS FOR SPENT NUCLEAR FUEL UNDER NORMAL STORAGE CONDITIONS

Ko, Jae-Hun,Park, Jea-Ho,Jung, In-Soo,Lee, Gang-Uk,Baeg, Chang-Yeal,Kim, Tae-Man Korean Nuclear Society 2014 Nuclear Engineering and Technology Vol.46 No.4

Korea expects a shortage in storage capacity for spent fuels at reactor sites. Therefore, a need for more metal and/or concrete casks for storage systems is anticipated for either the reactor site or away from the reactor for interim storage. For the purpose of interim storage and transportation, a dual purpose metal cask that can load 21 spent fuel assemblies is being developed by Korea Radioactive Waste Management Corporation (KRMC) in Korea. At first the gamma and neutron flux for the design basis fuel were determined assuming in-core environment (the temperature, pressure, etc. of the moderator, boron, cladding, $UO_2$ pellets) in which the design basis fuel is loaded, as input data. The evaluation simulated burnup up to 45,000 MWD/MTU and decay during ten years of cooling using the SAS2H/OGIGEN-S module of the SCALE5.1 system. The results from the source term evaluation were used as input data for the final shielding evaluation utilizing the MCNP Code, which yielded the effective dose rate. The design of the cask is based on the safety requirements for normal storage conditions under 10 CFR Part 72. A radiation shielding analysis of the metal storage cask optimized for loading 21 design basis fuels was performed for two cases; one for a single cask and the other for a $2{\times}10$ cask array. For the single cask, dose rates at the external surface of the metal cask, 1m and 2m away from the cask surface, were evaluated. For the $2{\times}10$ cask array, dose rates at the center point of the array and at the center of the casks' height were evaluated. The results of the shielding analysis for the single cask show that dose rates were considerably higher at the lower side (from the bottom of the cask to the bottom of the neutron shielding) of the cask, at over 2mSv/hr at the external surface of the cask. However, this is not considered to be a significant issue since additional shielding will be installed at the storage facility. The shielding analysis results for the $2{\times}10$ cask array showed exponential decrease with distance off the sources. The controlled area boundary was calculated to be approximately 280m from the array, with a dose rate of 25mrem/yr. Actual dose rates within the controlled area boundary will be lower than 25mrem/yr, due to the decay of radioactivity of spent fuel in storage.

Isonitrosoethylacetoacetate Imine 리간드의 니켈(II) 착물 합성 및 구조 특성

김인환,구본창,최강열,김상태,이만호 大邱大學校附設 基礎科學硏究所 1993 基礎科學硏究 Vol.10 No.-

Nickel(lI) Complexes of the type Ni(IEAA-NH)(IEAA-NR) (R = H₁, CH₃, C₂H_(5), n-C₃H_(7), n-C₄H_(9), or CH₂C_(6)H_(5)), where IEAA-NH and IEAA-NR represents isonitrosoethylacetoacetate imine and its N-alkyl derivative, respectively, have been prepared. And the structure of the complexes have been studied by elemental analyses, electronic, infrared,1H and 13C-NMR spectra. It has been determined that IEAA-NH ligand coordinates to nickel through the nitrogen of imine group and the oxygen of isonitroso group to form 6-membered chelate ring and IEAA-NR coordinates to nickel through the nitrogens of imino group and isonitroso group to form 5-membered chelate ring in the square-planar Ni(IEAA-NH)(IEAA-NR) complexes.

Identification of genetic diversity and DNA polymorphisms in Korean rice accessions through resequencing

In-Seon Jeong,Ung-Han Yoon,Gang-Seob Lee,Hyeon-So Ji,Hyun-Ju Lee,Tae-Ho Kim 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07

With the rapid development of sequencing technologies, next-generation sequencing is widely utilized for molecular breeding in several crops including rice. We performed whole genome resequencing of ten Korean rice accessions including six cultivars and four mutant lines. In total, 2,448 million raw reads were generated with over 58x coverage of Nipponbare genome. We mapped the reads from each of the ten accessions onto genomic sequence of japonica rice cultivar, Nipponbare. We detected 3,144,016 SNPs, which estimated to be one per 2.2kb on average. We found SNPs in genes that have been reported to be involved in rice flowering time regulation and bacterial blight resistance among ten rice accessions. Unmapped region against Nipponbare genome occupied about 1 ~ 2% in each accession. Over 50% of the unmapped region were found in the repeat region. The minimum length of gap in all accessions were 1bp and the maximum length of gap was 45,967bp in Ilpum. We also identified 3,497 possible gene loss events within these unmapped regions. The frequency of gene loss in each chromosome ranged from 33 on chromosome 5 to 913 on chromosome 11. The genetic variations we detected among ten rice accessions will provide invaluable resources for identification of genes associated with diverse traits of agronomical importance for molecular breeding.

Diagnostic ability of differential diagnosis in ameloblastoma and odontogenic keratocyst by imaging modalities and observers

Gang, Tae-In,Huh, Kyung-Hoe,Yi, Won-Jin,Heo, Min-Suk,Lee, Sam-Sun,Kim, Jeong-Hwa,Moon, Je-Woon,Choi, Soon-Chul 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.4

Purpose : To evaluate the diagnostic ability in differentiating between ameloblastoma and odontogenic keratocyst according to the imaging modalities and observers. Materials and Methods : We evaluated thirty-six cases of ameloblastomas and forty-seven cases of odontogenic keratocysts all histologically confirmed. Six oral and maxillofacial radiologists diagnosed the lesions by 3 methods: using panoramic radiograph, using computed tomograph (CT), and using panoramic radiograph and CT. The observers were classified by 3 groups: group 1 had experienced over 10 years in oral and maxillofacial radiologic field, group 2 had experienced for 3-4 years, and group 3 was in the process of residentship. After over 2 weeks, the observers diagnosed them by the same methods. Results : The ROC curve areas except for group 3 were the highest with interpretation using panoramic radiograph and CT, followed by interpretation using CT only, and the lowest with interpretation using panoramic radiograph only. The overall difference was not found in diagnostic ability among groups in using panoramic radiograph only, but there was difference in diagnostic ability of group 1 and 2 vs 3 in using CT only, and combination panoramic radiograph and CT. Conclusions : To differentiate between ameloblastoma and odontogenic keratocyst more accurately, the experienced oral and maxillofacial radiologist should diagnose with combination of panoramic radiograph and CT.

Identification of genetic polymorphisms in Korean rice accessions by Whole-genome sequencing

In-Seon Jeong,Ung-Han Yoon,Gang-Seob Lee,Hyeon-So Ji,Hyun-Ju Lee,Tae-Ho Kim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

Advances in genome sequencing technologies have aided discovery of millions of genome-wide DNA polymorphisms, single nucleotide polymorphisms (SNPs) and insertion-deletion (InDels), which are an invaluable resource to analyze genetic diversity in a population. We performed whole-genome resequencing of ten Korean rice accessions including six cultivars and four mutant lines. A total of 2,447 million raw reads were generated with over 58x coverage and detected 3,240,025 DNA polymorphisms between the Korean rice accessions and Nipponbare as reference genome. We observed that in ten Korean rice accessions, the frequency of potential SNPs was estimated to be one per 2.1kb on Nipponbare (382Mb). Potential SNPs were classified into two types, homozygous SNP and heterozygous SNP, which approximately 87% of the total was homozygous SNPs from ten accessions and heterozygous SNPs accounted for 13%. According to annotation of DNA polymorphisms, 634,620 SNPs were found in gene region, and only 169,738 SNPs were occurred in coding region. Altogether, 86,251 non-synonymous SNPs were located on 76,891 genes. We also examined genes which had at least one SNP in all ten accessions. It was estimated that the total of 290 genes had one or more non-synonymous SNPs and 25 genes had only synonymous SNPs. These genes were functionally classified based on gene ontology (GO). These DNA polymorphisms obtained from our result will provide an invaluable resource to identify molecular markers and genes associated with diverse traits of agronomical importance.

대장 용종에서 겸자생검과 용종절제술 사이의 병리조직 소견의 비교

송인성,김용태,김재준,최규완,김정룡,이국래,윤용범,최상운,차수강,고광철 대한소화기내시경학회 1993 Clinical Endoscopy Vol.13 No.2

Colonic polyps are one of the most risky factors far colon cancer. The, pathology of the specimen obtained by forceps biopsy does not represent the whole specimen of the polyp obtained by polypectomy or surgery in some cases. To evaluate these pathologic differences, we analysed the 39 patients with colonic polyps who underwent forceps biopsy and polypsetomy. 1) The mean age was 53.6 years and tire ratio of ma1e to female was 2.5: 1. 2) 31 patients had single polyp and 8 patients had multiple polyps. 3) The sizes of polyps were under 1 cm in 7 cases(18%), 1 to 2cm in 20 cases (51%), and mare than 2 cm in 12 cases(31%). 4) Yamada type of the polyps were type I in 2 cases(5%), type II in 1 case (3%), type III in 3 cases(8%) and type IV in 33 cases(85%). 5) The mean sample number of the tissue obtained by forceps biopsy was 3.2. 6) Pathologic findings of forceps biopsy were consistent with that of polypectomy in 30 cases (77%) out of 39 cases. 7) Out of 27 adenomatous polyps with forceps biopsy, one case(4%) turned out to have adenocarcinnoma. Out of 11 non-neoplastic polyps with forceps biopsy, 3 cases(27%) turned out to have adenomatous polyps(2 cases) and to have sderaocarcinoma(1 case). In conclusion, pathologic findings of the specimen obtained by forceps biopsy is not consistent with that by polypectomy in some cases. Thus it is concluded that polypectomy is necessary for all cases. If polypectcmy is impossible initially, laserphotocoagtylatian ar electrocaagulation after forceps biopsy or strip biopsy is recommended.