Three Poems by Yun Dong-ju

Yun Dong-ju,Lee In-soo(번역자) The Academy of Korean Studies 1965 Korea Journal Vol.5 No.9

Combination treatment for onychomycosis using 1,064-Nd:YAG laser and efinaconazole 10% topical Solution

( Sang Ju Lee ),( Dong Woo Suh ),( Won Soon Chung ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Onychomycosis is one of the most common nail disease around the world. No specific treatment other than drug therapy and surgery has been suggested till present. Systemic treatment with antifungal drugs for onychomysosis is effective. However, a long treatment time is required and it is not suitable for people with other systemic disease. Furthermore, it may cause many side effects such as liver diseases. For that reasons, topical drugs or physical treatments are preferred by many patients. Recently laser treatment for onychomycosis has been proposed. The efficacy of treatment is less than systemic drugs but, laser is more convenient, safe and accessible in treatment. As a result, the combination therapy using 1064 Nd:YAG laser and efinaconazole 10% topical solution was performed. Two patients with onychomycosis were treated with 1064 Nd:YAG laser (PinPointe FootLaser, Cynosure, Westford, MA, USA) once a month with application of 10% eifnaconazole solution(Jublia, Dong-A EST) once a day. All three patients were treated successfully. We considered a combination treatment of a 1064 Nd:YAG laser and efinaconazole 10% topical solutions would be an effective, safe, and convenient treatment method for onychomycosis.

Combination treatment for onychomycosis using 1,064 Nd:YAG laser and efinaconazole 10% topical solution

( Sang Ju Lee ),( Dong Woo Suh ),( Won Soon Chung ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Onychomycosis is one of the most common nail disease around the world. No specific treatment other than drug therapy and surgery was suggested till present. Systemic antifungal drugs for onychomysosis are effective. However, they require a long treatment time and not suitable for people with other systemic disease. Furthermore, they may cause many side effects such as liver disease. Also, many patients prefer topical drugs or physical treatment. Objectives: The objective of this study was to evaluate the efficacy of combination treatment with a 1064 Nd:YAG laser and efinaconazole 10% Topical Solution. Methods: Ten patients with onychomycosis were treated with 1064 Nd:YAG laser (PinPointe FootLaser, Cynosure, Westford, MA, USA) once a month with application of 10% eifnaconazole solution(Jublia, Dong-A EST) once a day. The effectiveness of treatment were evaluated with before and after photographs. Results: Improvement were shown in 90% of patients after the treatment. However, 10% of patients had no response. Conclusion: This clinical study suggests that combination treatment of a 1064 Nd:YAG laser and efinaconazole 10% Topical Solutionis an effective, safe, and convenient treatment method for onychomycosis.

Alkylhalide가 Mouse의 LDH isozyme 분포에 미치는 영향 : Cellulose Acetate Electrophoresis Method

권미경,김영옥,박은주,이동화,이명미,이문희,이양자 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

The effect of Carbontetrachloride administration on Lactatedehydrogenase isozyme patterns were analyzed by cellulose acetate electrophoresis for the brain, heart, kidney, lung, liver and mouse muscle. Each other tissue was found to have a characteristic distribution of these isozymes. At normal condition, aerobic tissue such as brain, heart, kidney, and lung were found to have all five isozymes from LDH_1 to LDH_5, while anaerobic tissues such as liver and muscle were found to have superiorly LDH_5 The toxicity of Carbontetrachloride administration was most prominence in the liver, and lung toxicity was occured also.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

연령 및 가정에서의 인터넷 환경이 인터넷 이용행태에 미치는 영향

이현주,심성훈,신동일 한국항공대학교 경영연구소 2001 경영연구 Vol.8 No.1

인터넷이 확산되면서 정보접근에 있어 사회 계층별로 더 큰 격차를 보이게 되었다. 초고속 인터넷 접속서비스의 급속한 보급으로 우리나라가 세계 최고 수준의 인터넷 이용률을 보이게 되면서 가정에서의 초고속 인터넷 접속 서비스 이용여부가 가구원 개인의 정보이용에 적잖은 영향을 미치고 있으며, 또한 연령대에 따라서도 많은 차이를 보이고 있다. 본 연구에서는 실증분석을 통해 이 두 변수에 의한 집단구분이 인터넷 이용장소, 이용시간, 이용빈도, 즐겨 찾는 사이트, 전자상거래 이용경험과 같은 인터넷 이용행태에 유의적인 차이를 발생시킴을 보이고 있다. The growth of internet use makes larger difference in information access among social classes. Rapid diffusion of broadband internet access at home enables Korea the highest internet penetration among OECD countries. So the accessibility of broadband service effects a lot on the information usage and also great difference with age. This study shows that there is significant difference in internet access location, time, frequency of access, favorite site and use of e-commerce according to two variables through empirical investigation.

황산산성 용액에서 기체 발생 속도에 의한 히드라진과 요오드의 반응속도에 관한 연구

이송주,박동화 광주보건대학 1989 論文集 Vol.14 No.-

We have studied the kinetics of the N₂H₄=l₂ reaction in sulfuric acid media by gas evolution Choi?? has explained that the reaction of N₂H₄-Br₂processes through the Competitive Consecutive Second order reaction mechanism, and we have assumed N₂H₄-l₂ reaction processes through the same mechanism. The rate constant(k'₁) was found to be 0.87~0.98X 10^(-1) M^(-1) sec^(-1) with change in [N₂H₄]_(0), [l₂]_(0), 2a(=2[N₂H₄3_(0)-(l₂]) and inversely proportional to hydrogen concentration. we have also found th at, as k₃ is constant, a comparatively stable intermediate is present .

조혈모세포이식 후 발생한 주폐포자층 폐렴에 대한 고찰

주지현,최정현,이동건,백지연,고윤호,이혜정,김세희,신호진,박윤희,박지영,김유진,신완식,김춘추 대한감염학회 2001 감염 Vol.33 No.4

Background : Pneumocytitis cainii pneumonia (PCP) can occur in immunocompromised hosts especially such as AIDS or cancer patients. Although recent research had focused on PCP in AIDS patients, few studies have described the clinical presentations of PCP in recipients of stem cell transplantation (SCT). We evaluated the clinical manifestations of PCP in SCT patients admitted at St. Mary's hospital, Seoul, Korea. Methods : The medical records of 17 PCP patients undergoing SCT between Feb. 1998 and Feb. 2000 were reviewed. The diagnosis of PCP was confirmed through the demonstration of Pneumocytitis cainii via either cytology of brochoalveolar lavage (BAL) or histological technique of lung biopsy. CMV disease and CMV infection were confirmed by BAL culture and antigenemia respectively . Results : Seventeen patients were all recipients of allogeneic SCT and 7 of 17 patients were performed non-sibling SCT. Patients presented with symptoms including brief period (4 ∼23 days) of fever (76%), dyspnea (70%), cough (64%), and signs such as rare(58.8%), Sixteen patients (94%) had been receiving immunosuppressive agent such as cyclosporine A (64%) or Fk506 (35%) without PCP prophylaxis. Eleven patients (64%) were treated with corticosteroid with mean dose of 16 mg/day prednisolone and mean duration of 4.6 months after post-SCT period. Twelve patients were co-infected with CMV. Another co-infected miCroorganisms were Pseudomonas aeruginosa, Mycobacterium tuberculosis, herpes simplex virus, parainfluenza virus, Average duration of treatment with trimethoprim-sulfamethoxazole (TMP/SMX) was 21 ±9 days. Four patients died, and three of them were related with PCP. Conclusion : PCP developed frequently in patients who were taking immunosuppressive drug due to graft versus host disease or were not taking TMP/SMX prophylaxis. High risk patients showing fever, cough, or dyspnea should be considered to take early bronchoscopic intervention for detection of PCP. When treat for PCP, it also be considered to the possibility of coinfection such as CMV. (Korean J Infect Dis 33:273∼279, 2001)

杜詩章法硏究

李永朱 한국중국어문학회 2000 中國文學 Vol.33 No.-

杜詩盡發古今之體勢, 而無所不備, 尤其是章法, 卓然獨高, 古今無比, 當謂詩家之模辯. 自筆者所窺而說之, 其章法略有三指向. 其一, 要融合相反相背之二律. 其二, 要探究所以貫通諸體之章法. 其三, 要試作變格,拙讀, 緣於地面限制, 不得不止於其一之一部分而已. 其餘期於下回續論. 此回所論, 大槪始 一, 杜誇融合相反之二律, 以造咸其所擅長之嚴密結構, 當展開誇想時, 置重於轉變, 又資脈絡應接, 因此文勢自有似斷不斷, 相應相避之妙, 恰如行雲流水, 或流暘, 或頓挫, 變化無窮, 而不露斧遊. 二, 杜誇, 無古律無長短, 每篇布置整密, 每段分界謹嚴, 行文自有起伏. 各段句數, 必訓於漏意, 多寡勻稱, 詳略相應. -篇之內, 必有開頭本論末謠之結構, 開頭破題以領下, 末尾承上暇或就題結, 彧開一步, 本論所言, 井幷有條, 意興迭出, 以示章法之妙諦.

대장암에서의 nm23과 CD44 단백질 발현에 대한 면역조직학적 분석

신동일,이기형,윤충,이주희 대한대장항문학회 1997 Annals of Coloproctolgy Vol.13 No.1