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Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants
Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9
The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.
김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-
The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.
제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방
김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-
The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.
의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향
허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1
Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.
강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1
There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.
류재청 濟州大學敎 體育科學硏究所 1999 체육과학연구 Vol.5 No.-
The purpose of this Consideration was to suggest basic sports industry guidline and investigate developmental consideration as meca of global sports industry of CheJu-Do. It will be necessary for Cheju-Do's sports industry to develop hardware facilities and software program on the basis of characteristics of clear sky- ocean of 4 plane-mid level altitude area-subtropic area background in terms of farsighting for 21c globalization and meca of sports industry.
해조류 에탄올 농도별 추출물의 항돌연변이원성 및 항균성
박제석,오명철,오창경,현재석,김봉오,김수현 濟州大學校工科大學産業技術硏究所 1996 尖端技術硏究所論文集 Vol.7 No.2
톳. 미역 및 다시마의 에탄올 농도별 추출물이 MMS. ICR191 및 sodium azide에 의해 유도되는 돌연변이원성의 억제효과 및 E. coli, B. subtilis 및 S. serevisiae에 대한 항균효과를 검정하였다. 톳의 90% 에탄올 추출물은 MMS와 ICR191에 대한 항돌연변이 원성이 각각 70 및 95% 이상으로 매우 높았으나, sodium azide에 대한 항돌연변이원성은 없었다. 미역의 에탄올 농도별 추출물은 30∼90% 에탄올 추출물에서 50% 이상의 항돌연변이 효과를 보았으나 MMS와 sodium azide에 대한 항돌연변이 효과는 없었다. 다시마의 30∼90% 에탄올 추출물의 ICR191에 대한 항돌연변이 효과는 70% 이상이었으나, MMS와 sodium azide에 대한 효과는 없었다. 에탄올 농도별 톳의 추출물들에 대한 항균성 검색 결과 70과 90% 추출물들이 E. coli와 B. subtilis에 대하여 뚜렷한 항균효과는 미역 추출물 보다 다시마의 추출물이 더욱 요과적이었다. 미역 추출물은 50% 추출물만이 S. cerevisiae에 대한 성장저지효과를 나타낸 반면, 다시마 추출물은 90% 에탄올 추출물에서는 시험된 모든 공시균주에 대하여, 그리고 70% 에탄올 추출물에서는 E. coli와 B. sutilis에 대하여 높은 성장저지효과를 나타내었다. Desmutagenic against MMS-, ICR191- and sodium azide-induced mutations, and antimicrobial effects against Escherichia coli, Bacillus subtilis and Saccharomyces cerevisiae by the extracts from Hizikia fusiforme. Laminaria japonica and Undaria pinnatifida with ethanol of a different concentrations were investigated. Desmutagenic effects against MMS and ICR191 of 90% ethanol extracts from Hizikia fusiforme were up 70 and 95%. respectively. no against sodium azide. Desmutagenic effects against ICR191 of 30∼90% ethanol extracts from Undaria pinnatifida and Laminaria japonica were up to 50 and 70%. respectively. but no against sodium azide and MMS. Antimicrobial effect of 70 and 90% ethanol extracts from Hizikia fusiforme had potent antimicrobial activities against E. coli and B. subtilis. Ethanol extracts from Laminaria japonica showed more effective antimicrobial effects than those from Undaria pinnatifida. Only 50% ethanol extract from Undaria pinnatifida showed growth inhibition effect against S. cerevisiae. Seventy percent ethanol extract from Laminaria japonica showed growth inhibition effect against all strains tested. while 90% ethanol extract showed against E. coli and B. subtilis.
DCT 기반 영상압축에서 각 블록의 구성요소 선택 기준
조제황 東新大學校 1997 論文集 Vol.9 No.-
The DCT is applied to a 8×8 block and the low frequency coefficients are selected to compress. Because RMSE and the standard deviation for unselected coefficients versus each block present similar distribution, the standard deviation can be utilized to decrease the complexity and bit rate of a compression system. In 3 to 5 standard deviation, the proposed method has around 2dB lower PSNR than only b selection, but has the number of coefficients around four times as small as only b selection.
지속적인 음악 줄넘기 운동이 초등학생의 기초체력 및 흥미도에 미치는 영향
문채련 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5
The study was performed to make a comparison and to analyse the effect on basic physical strength and interesting degree of primary school students by continuous "skipping rope to music". The test was done in a way that the experimental group of 119 persons and the comparative studying group of 113 persons were tested and analyzed about "physical elasticity, agility, balancing power, sustaining power of heart and lungs, pliability, and interesting degree" before and after skipping rope to music. It was resulted that in the first, continuous skipping rope to music makes considerable effects to improve physical adjusting abilities (physical elasticity, balancing power, agility) and especially, showed the considerable change on statistical data of physical elasticity. In the second, continuous skipping rope to music made significant effects to advance sustaining power of heart and lungs, which may lead to increase of sustaining power of heart and lungs and to improvement of physical circulation system. In the third, muscular strength whs considerably increased by the continuous skipping rope to music, In the fourth the continuous "skipping rope to music" made student think about skipping rope in a good way and it was found that students were more interested in skipping rope together with others than in doing that alone. In line with the above facts, 36 weeks of skipping rope to music resulted in improvement and advancement of basic physical power of primary school students, and it played an important role to make students get interested in doing that, and furthermore, the continuous development of physical training program is expected in the future for a large number of primary school students through readjusting training times and level of "skipping rope to music".
장재철,성금수,김동원 군산대학교 기초과학연구소 2000 基礎科學硏究 Vol.15 No.-
The purpose of this study is to investigate the pollution characteristics of groundwaters in Kansan city. Volatile organic compounds such as TCE(tri-choroethylene), PCE(tetruchloroethylene), 1,1,1-trichloroethane, THM(trihalo-methane), dichloromethane, pesticides such as diazinon, parathion, malathion, toxic inoganic matters such as As, Hg, Se, Cd, Al, Cr6+, oder, taste and phenol were not detected in the groundwaters. Mean values of groundwater pollution indicators were bellow drinking-water standards, but Bacteria, Total Coliforms, Pb, Mn, NO3-N and NH3-N, total solid and pH exceeded a little in some samples.