일반연제 발표 : 부인과종양학 ; 항암제를 처리한 HeLa세포의 DNA합성 억제에 미치는 인삼추출물의 영향

최영배,윤지열,노흥태 대한산부인과학회 1990 대한산부인과학회 학술대회 Vol.66 No.-

건물에너지시뮬레이션을 활용한 육계사 사육환경 및 에너지부하 평가, Part 2: 지역 및 축사구조에 따른 모델 적용

최영배,이인복 (사)한국축산환경학회 2023 한국축산시설환경학회지 Vol.25 No.3

With a significant portion of poultry production costs, efficient energy management is imperative for sustainable growth. This study evlauated the influence of regional climate variations and structural configurations of broiler houses on their internal environments and energy demands using previously validated Building Energy Simulation (BES) model. The analysis indicated distinct thermal conditions within broiler houses, primarily driven by regional climate differences and building structures. The model effectively demonstrated the effects of various wall compositions and ventilation systems. The installation of ceiling structures in broiler houses showed a pronounced impact on maintaining appropriate rearing temperatures. Specifically, during winter, the mid-ceiling installations led to a temperature rise of up to 4.5°C, effectively reducing heating loads by 4.7% to 5.7% across various regions. In summer, activating ceiling fans in conjunction with mid-ceiling structures reduced cooling loads by 9.0% to 2.4%. These results underscore the importance of tailored building designs, ventilation systems, and energyefficient practices for broiler houses in diverse climatic conditions. The study suggests that dynamic energy simulations could contribute to the development of more sustainable and climate-adaptive practices in broiler farming.

2005년과 2006년 경주 지역에서 유행한 인플루엔자의 임상적 고찰 및 인플루엔자 신속 항원 검사법의 유용성

최영배,송화,최성민,김두권,이동석,이선주,김애숙,하경임 동국대학교 의학연구소 2008 東國醫學 Vol.15 No.1

인플루엔자는 매년 겨울 유행하는 급성 호흡기 감염으로 진단은 주로 임상 증상에 의존하였다. 저자들은 2005년, 2006년 경주에서 유행한 인플루엔자 감염 환아들에 대해 임상적 고찰과 신속 항원 검사법의 결과에 대해 평가하였다. 2005년 11월부터 2006년 2월까지 동국대학교 경주병원 소아과 내원 환자 중 인플루엔자 의심 환자를 대상으로 인후 도찰물 및 콧물을 채취하여 QuickVue 또는 SD 인플루엔자 테스트를 시행하고 검체에서 인플루엔자 바이러스를 배양하였다. 80명의 환아 중 인플루엔자 바이러스 배양 양성은 32례이었으며 인플루엔자 신속 항원 검사 양성은 40례이었다. 예민도 93%, 특이도 83.3%, 양성 예측도 75%, 음성 예측도 95% 이었으며 인플루엔자 바이러스가 분리된 환아들 중 influenza A형이 32례, B형이 0례였다. Influenza A형중 H1N1형이 3례였으며 H3N2형이 29례였다. 남녀성비는 1.9:1 이었으며 중심나이는 4년6개월 이었다. 인플루엔자 신속 항원 검사법의 사용으로 인플루엔자 감염을 신속하게 진단할 수 있으며 증상이 심한 환아의 경우 조기에 항바이러스제를 사용하고 인플루엔자가 진단된 환아를 조기에 격리하여 인플루엔자 바이러스 감염의 전파를 줄일 수 있을 것이다. Although influenza is an epidemic acute respiratory infection every winter, the diagnosis of influenza depends on mainly the clinical sypmtoms in Korea. We evaluated the clinical features of influenza virus infection in children and the use of rapid antigen detection tests in 2005 to 2006 in Gyeongju. From November 2005 to February 2006, throat and nasal swabs were obtained from the children with suspected influenza infection to isolate influenza viruses and to test by rapid antigen detection tests. The medical records of the patients with influenza virus infection were reviewed retrospectively. Influenza viruses were isolated in 32 cases of 80 patients examined, while 40 cases were positive in the rapid antigen detection tests. The sensitivity obtained from rapid antigen detection tests was 93%, the specificity 83.3%, the positive predictive value 75%, and the negative predictive value 98.8%. All cultured influenza viruses were type A. Twenty nine cases were H3N2 subtype, and 3 cases were H1N1. The ratio of male to female with influenza virus infection was 1.9:1, and the median age was 4 years 6 months. The use of rapid antigen detection tests was valuable for the diagnosis of influenza infection in children. In order to reduse the spreading of influenza virus, the rapid diagnosis by these tests the isolation of the patients with influenza infection, and the use of antiviral agents in the early stage are necessary.

High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Children with High-Risk or Recurrent Bone and Soft Tissue Sarcomas

최영배,이은상,이지원,유건희,성기웅,구홍회 대한의학회 2016 Journal of Korean medical science Vol.31 No.7

Despite increasing evidence that high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) might improve the survival of patients with high-risk or recurrent solid tumors, therapy effectiveness for bone and soft tissue sarcoma treatment remains unclear. This study retrospectively investigated the feasibility and effectiveness of HDCT/auto-SCT for high-risk or recurrent bone and soft tissue sarcoma. A total of 28 patients (18 high-risk and 10 recurrent) underwent single or tandem HDCT/auto-SCT between October 2004 and September 2014. During follow-up of a median 15.3 months, 18 patients exhibited disease progression and 2 died of treatment-related toxicities (1 veno-occlusive disease and 1 sepsis). Overall, 8 patients remained alive and progressionfree. The 3-year overall survival (OS) and event-free survival (EFS) rates for all 28 patients were 28.7% and 26.3%, respectively. In the subgroup analysis, OS and EFS rates were higher in patients with complete or partial remission prior to HDCT/auto-SCT than in those with worse responses (OS, 39.1% vs. 0.0%, P = 0.002; EFS, 36.8% vs. 0.0%, P < 0.001). Therefore, careful selection of patients who can benefit from HDCT/auto-SCT and maximal effort to reduce tumor burden prior to treatment will be important to achieve favorable outcomes in patients with high-risk or recurrent bone and soft tissue sarcomas.

LSS(Laser Seam Stepper)를 이용한 초고강도강 차체부품(Panel Assembly Rocker) 기술 개발

최영배,김준수,이광원 대한용접·접합학회 2021 대한용접학회 특별강연 및 학술발표대회 개요집 Vol.2021 No.11

현재 초고강도강(1.5GPa급) 제품의 롤 포밍 공정의 품질 저하 문제와 조립 공정 중 생산 효율이 낮은 용접 공정으로 인한 생산성 저하 문제가 발생되고 있다. 이러한 문제 해결을 위해서는 롤 포밍 공정의 단품 품질을 개선하여 불량률을 감소시킬 수 있는 품질 안정화 기술과 높은 생산 효율을 확보할 수 있는 용접 시스템 개발을 통한 생산 고도화 기술 개발이 필수적으로 요구되고 있다. 이를 해결하기 위해 품질 안정화 기술을 개발하여 불량률을 감소함과 동시에 시스템 최적화를 통해 생산 고도화 기술 개발을 진행하고자 한다. 본 발표에서는 산업통상자원부 양산성능평가 일환으로 추진 중인 “1.5GPa급 초고강도강 차체부품(Panel Assembly Rocker) 생산 고도화 기술 개발”의 연구내용이다. 본 과제에서 제작되는 Panel Assembly Rocker 부품의 주요 기능은 자동차 측면 충돌 시 충돌 에너지를 흡수하여 충격으로부터 운전자 및 탑승자를 보호하는 부품으로 정의된다. 본 과제에서 사용되는 레이저 심 스테퍼(이하 LSS용접 )용접은 점용접 대비 선 용접의 특성을 가짐으로써 비틀림 강성이 2~20% 강화되는 장비이다. LSS 용접은 비드형상을 변화하여 점 용점 부위에서 발생되는 응력 집중을 완화 시키며, 접합 플랜지 (Flange) 감소를 통한 차체 경량화를 구현할 수 있으므로 고 품질의 고강성 경량 차체 개발이 가능할 것으로 기대된다.

Impact of Day 14 Peripheral Blood Chimerism after Allogeneic Hematopoietic Stem Cell Bone Transplantation on the Treatment Outcome of Non-Malignant Disease

최영배,이지원,성기웅,구홍회,김희진,유건희 대한의학회 2019 Journal of Korean medical science Vol.34 No.6

Background: The impact of early peripheral blood chimerism on the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We aimed to determine whether day 14 peripheral blood chimerism after allo-HSCT predicts outcomes in patients with non-malignant diseases. Methods: Data from 56 patients who received allo-HSCT between April 2007 and March 2016 were retrospectively analyzed. Chimerism was evaluated using short-tandem repeat polymerase chain reaction, with mixed chimerism (MC) defined as greater than 1% recipient cells which was further categorized into low-level MC (> 1% and < 15% of recipient-derived cells) and high-level MC (≥ 15% of the recipient-derived cells). Results: Thirty-six patients showed complete donor chimerism (CC), 14 low-level MC, and 6 high-level MC at day 14 post-transplant. The estimated 5-year event-free survival (EFS) was higher in the CC or low-level MC groups than in the high-level MC group (86.1% vs. 71.4% vs. 33.3%; P = 0.001). In BM or peripheral blood stem cell (BM/PBSC) transplants, the 5-year EFS was higher in the CC or low-level MC group than in the high-level MC group (93.1% vs. 66.7% vs. 0%; P < 0.001). However, in cord blood transplants, the 5-year OS and EFS according to the day 14 peripheral blood chimerism did not reach statistical significance. Conclusion: Although CC is not always necessary after allo-HSCT for non-malignant diseases, our data suggest that day 14 peripheral blood chimerism may predict outcomes in patients with non-malignant diseases who underwent BM/PBSC transplants.

로봇기반 마찰교반용접 기술개발 현황

최영배,안영남,이광원 대한용접·접합학회 2019 대한용접학회 특별강연 및 학술발표대회 개요집 Vol.2019 No.11

한국에 있어서의 히이트 펌프계의 최적 설계 조건에 관한 연구

최영배,Choe, Yeong-Bae 대한설비공학회 1981 설비저널 Vol.10 No.4

This paper presents, the result of the study for the fluctuant temperature of the out-side air adopting the heat pump system in seoul, Taejean, Taegu, Busan and Jejeu among principle cities in korea for the purpose of checking the heating capacity, Heat pump capacity (outlet capacity), Coefficient of performance and running cost in comparison with the supporting the energy for the boiler's operation. According to the supply temperature changes of the out door coil by the out side air-return air mixing ratio, the Coefficient of performance is increased from 3. 1 to 5.0. Particularly, in Taegu, it is necessary to adopt the heat pump system against the supplement heat supply on the full outside air intake in January of the heating period, and it was recognized that the running cost is cheaper than that of the Boiler use. At the same time, if it is able to get $25\%$ of return air of the inside in the Seoul, it could be saved its costs when we use the supplementary boiler. And I think it is necessary to the development.

지역 MICE 산업 육성 정책에 따른 MICE 산업의 경제적 파급효과 추정 - 광주광역시를 중심으로 -

최영배,박효연,김동한 한국호텔리조트학회 2023 호텔리조트연구 Vol.22 No.4

The purpose of this study is to estimate the economic impact of the MICE industry based on the regional MICE promotion policies and to provide implications for MICE policies and developments. Since 2018, South Korea has been carrying out a vitalization policy by designating an Convention Integrated District, and among them, the current research focused on Gwangju Metropolitan City. In order to estimate the economic impact, an Inter-Regional Input-Output Model was applied, and the economic impact caused by the MICE industry in Gwangju Metropolitan City was estimated using published statistical data. Through the results, various implications for future development were presented.

개방된 통신 시장의 규제 완화와 NMF의 역할

최영배,박남훈,이계상,Choe, Yeong-Bae,Park, Nam-Hun,Lee, Gye-Sang 한국전자통신연구원 1996 전자통신동향분석 Vol.11 No.3

세계의 통신 시장이 개방되는 추세에 있고, 통신에 관한 규제가 완화됨에 따라 떠오르는 문제는 여러 가지 있겠으나 가장 큰 문제는 역시 표준화와 이에 따른 상호 운용성(interoperability)의 문제가 아닌가 생각한다. 본 고에서는 통신 분야의 서비스 관리에 있어서 세계적으로 주도적인 활동을 하고 있고, 그 중요성이 점차 부각되고 있는 NMF(Network Management Forum)의 역할에 대하여 소개하고자 하였다.