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아토피 피부염 동물모델에서 피부에 도포한 한약 복합추출물의 염증 억제 효과
조희찬,설현철,김순례,최한석,신용철,고성규,Cho, Hee-Chan,Sul, Hyun-Cheol,Kim, Soon-Re,Choi, Han-Seok,Shin, Yong-Cheol,Ko, Seong-Gyu 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.3
Objective : This study is conducted to evaluate the efficiency of ethanol extracts of 4 mixed herbs(CP001 or CP002) on mouse model of atopic dermatitis induced by ovalbumin. Methods : Female BALB/c mice were internally sensitized with ovalbumin($20{\mu}g$) plus aluminum hydroxide hydrate(4mg) once per week. After 3 weeks, they were dermally challenged with patches containing ovalbumin ($100{\mu}g$) plus aluminum hydroxide hydrate(20mg) every other day for 3 weeks. After induction of atopic dermatitis, mice back skin were gently rubbed with CP001 or CP002(200mg/$m{\ell}$, $100{\mu}{\ell}$) for two weeks(every 2 days). Results : In CP001 or CP002 treated group, there was a remarkable reduction in infiltration of eosinophils on the skin areas and diminution of mast cells and total T cells in blood samples as compared with control group. Cutaneous expressions of interleukin-13, 17 were also decreased by CP001 or CP002. Moreover, blood immunoglobulin E level was decreased by drug administration while there was no decrease in OVA sensitization group. Conclusion : In summary, our result shows that herbal extracts(CP001 and CP002) could be potential candidates for the treatment of chronic atopic dermatitis.
조민규 ( Min-gyu Cho ),엄종욱 ( Jong-wook Eom ),고희정 ( Hee-jung Go ),조희찬 ( Hee-cha Cho ),김동년 ( Dong-nyeon Kim ),이형봉 ( Hyung-bong Lee ) 한국정보처리학회 2020 한국정보처리학회 학술대회논문집 Vol.27 No.2
이번 캡스톤 디자인에서는 식당, 카폐 등 유명 장소 검색 시 날씨까지 함께 보여줄 수 있는 앱을 구현한다. 이 앱을 사용하는 사용자는 날씨 정보를 보면서 희망하는 장소를 검색하여 출장 업무나 여행 일정에 도움을 얻을 수 있다.
자원순환형(資源循環型) 사회(社會) 구축(構築)을 위한 고품질(高品質) 순환골재(循環骨材) 생산(生産) 공정(工程) 개발(開發) 연구(硏究)
김관호,조희찬,안지환,Kim, Kwan-Ho,Cho, Hee-Chan,Ahn, Ji-Whan 한국자원리싸이클링학회 2009 資源 리싸이클링 Vol.18 No.3
부존자원의 대량소비로 인해 자원고갈 문제와 이에 따라 발생하는 폐기물처리 문제가 대두되고 있는 가운데 두 가지 문제를 동시에 해결하기 위해 현재의 사회구조를 자원소비형에서 자인순환형으로 변화하기 위할 노력이 진행되고 있다. 이런 노력의 일환으로 국내 발생 폐기물 중 가장 높은 비중을 차지하고 있는 건설폐기물에 관심이 급증하고 있지만 종합적인 처리에 대한 연구는 미흡한 실정이다. 본 연구에서는 건설폐기물의 가장 많은 단일 물질인 폐콘크리트의 자원순환을 위한 고품질 순환골재 생산 공정 연구를 진행하였다. 굵은 골재, 잔골재, 시멘트 등이 수화물의 형태로 결합되어 있는 폐콘크리트를 가열전처리 방법과 Autogenous mill을 이용한 단체분리를 통해 고품질의 콘크리트용 순환 굵은 골재를 회수하였으며, 파분쇄 후 생산된 폐콘크리트 미분은 sink/float 분리를 통한 비중분리 특성을 파악한 후 간섭침강분리를 통해 정제과정을 거쳐 고품질의 콘크리트용 순환 잔골재를 생산하였다. 따라서 본 연구를 통해 전체 건설폐기물 중 가장 높은 비중을 차지하는 폐콘크리트를 고품질 순환골재로 재활용 할 수 있는 자원순환형 처리 공정을 개발하였다. To solve resource exhaustion and waste management problems caused by mass consumption, there are many efforts to change from resource consumption system to recycling system. Specially, interests about management of construction waste have increased, but efficient recycling system of waste concrete is not established yet. In this study, high quality recycled aggregate processing circuit was developed to recycle waste concrete. From the waste concrete which is a hydrated compound with coarse aggregate, fine aggregate, and cement material, high quality recycled coarse aggregate for concrete making was produced by autogenous milling and heat pretreatment method. After then, refinement process was performed to separate fine aggregate and cement material from waste concrete fines by sink float separation and hindered-settling separation. As a result, high quality recycled aggregate was produced from waste concrete by developed processing circuit.
정경식,조희찬,이승환,Jeong, Kyong-Shik,Cho, Hee-Chan,Yi, Seung-Hwan 한국전기전자재료학회 2008 전기전자재료학회논문지 Vol.21 No.6
This paper reports the characteristics of piezoelectric microspeakers that are audible in open air with high quality piezoelectric AlN thin film according to the materials properties. When we use a tensile-stressed silicon nitride diaphragm as a supporting layer, the Sound Pressure Level (SPL) is relatively small and constant at low frequency region and shows about 70 dB at 10 kHz. However, in case of a compressively stressed composite diaphragm, the SPL of the fabricated microspeakers shows higher output pressure than those of a tensile-stressed diaphragm. It produces more than 66 dB from 100 Hz to 15 kHz and the highest SPL is about 100 dB at 9.3 kHz with $20V_{peak-to-peak}$, sinusoidal input biases and at 10 mm distances from the fabricated microspeakers to the reference microphone. From the experimental results, it is superior to have a compressively composite diaphragm in order to produce a high SPL in piezoelectric microspeaker.
화학적 분해법을 이용한 난용성 자원으로부터 희토류 회수 특성 연구
김리나,조희찬,정진안,김지혜,이수경,Kim, Rina,Cho, Heechan,Jeong, Jinan,Kim, Jihye,Lee, Sugyeong 한국자원리싸이클링학회 2020 資源 리싸이클링 Vol.29 No.1
In this study, rare earth elements (REE) leaching from a refractory REE ore containing goethite as a major gangue mineral was conducted, introducing a two-stage method of chemical decomposition-acid leaching. At the chemical decomposition step, using one of alkaline agent, NaOH, the ore was decomposed, changing NaOH concentration from 20 to 50 wt% at 10% (w/w) of pulp density and the maximum temperature achieved without boiling at each NaOH concentration. With increasing NaOH concentration, light REE (Ce, La and Nd) and iron were concentrated in the solid phase which is the decomposed product, while aluminum (Al) and phosphorus (P) were removed to the liquid phase, and their concentrations in the solid phase were down to 0.96 and 0.17%, respectively. In addition, through XRD analysis, it was found that the crystallinity of goethite was considerably decreased. At the acid leaching step, the product decomposed by 50 wt% NaOH was leached at 3.0 M HCl and 80 ℃ for 3 hr, then the REE leaching efficiency was above 94% (Ce 80%), and the leaching efficiencies of Al and P were decreased to 12 and 0%, respectively. Therefore, in terms of both REE leaching efficiency and impurity removal, those decomposition and leaching conditions were chosen as optimum processing methods of the investigated material. In terms of REE leaching mechanism, because REE and iron leaching efficiencies showed the positive correlation each other, so it can be concluded that decreasing crystallinity of goethite affect the improvement of REE leaching.
금(金) 광산(鑛山) 광미(鑛尾)로부터 유가자원(有價資源) 회수(回收)에 관한 연구(硏究)
오원,조희찬,이진수,Oh, Won,Cho, Hee-Chan,Lee, Jin-Soo 한국자원리싸이클링학회 2010 資源 리싸이클링 Vol.19 No.6
가행중인 금(gold) 광산에서 발생하는 광미(tailing)로부터 금 및 실리카와 같은 유가자원을 회수하기 위해 선별특성을 검토하였다. 금 선별에는 고비증액(heavy liquid}을 이용한 비중선별(gravity separation)을 하였고, 실리카 선별에는 하이드로싸이클론을 이용한 분급/비중선별, 부유선별(froth-flotation) 그리고 마찰대전형 정전선별 (triboelectrostatic separation)을 하였다. 실험결과 금은 비중액의 비중이 2.72일 때 품위가 최고 5.58 g/ton인 정광을 약 3 wt.% 회수하였으며, $SiO_2$의 함량이 약 94%인 고순도 실리카를 회수할 수 있었다. 따라서, 본 연구를 통하여 환경을 훼손하는 광미의 감량 및 무해화는 물론 유가자원 회수를 위한 공정을 수립 할 수 있을 것으로 기대된다. This study was carried out to develop a process flow sheet for recovering valuables (gold and high purity silica) from the gold mine tailings containing 1.7 g/ton of gold and 79.48 wt.% $SiO_2$. Float-sink tests using heavy liquids was conducted to explore the possibility of recovering gold by gravity separation. Hydrocyclone, froth flotation, and triboelectrostatic separatoin tests were conducted to recover high purity silica from the gold mine tailings. The results of float-sink tests showed that particles containing 5.58 g/ton of gold could be obtained at 2.72 specific gravity, but with very low yields around 3%. Meanwhile, all tests with hydrocyclone, froth flotation, and triboelectrostatic separation showed that high purity silica with $SiO_2$ content over 90% could be obtained. The purity could be improved further up to about 94% by employing several recleaning steps in the froth flotation and triboelectrostatic process.
한지영,조희찬,김도균,Han Ji Young,Cho Hee Chm,Kim Do Kyun 한국자원리싸이클링학회 2002 資源 리싸이클링 Vol.11 No.4
폐기물 관리법에 의하면 2001년부터 슬러지의 매립이 금지됨에 따라, 매립이외의 다른 처리방식을 도입해야 할 상황이다. 전과 정평가는 제품 및 서비스의 전과정을 통해서 발생하는 환경부하를 정량화 하는 방법으로 대두되고 있으며 환경성에 대한 정책의 입안 및 제품의 비교평가 등 그 활용분야가 다양하다. 본 논문에서는 전과정평가(Life Cycle Assessment, LCA)를 이용하여 슬러지의 처리방법 중 소각, 퇴비화, 고형화에 대한 환경성을 비교 평가하여 적절한 처리방식을 선정하는데 도움이 되고자 하였다. 각각 처리시설의 Data는 구리시 하수처리장의 소각시설, 난지도 하수처리장의 퇴비화 시설, 수도권매립지의 고형화 처리시설을 방문하여 운영자료를 사용하였으며, 국내 D/B로 구축된 전력 및 수송자료도 이용하였다. 전과정 평가를 수행한 결과 퇴비화가 가장 낮은 환경 부하를 나타냈고. 고형화 처리방식이 가장 큰 환경부하를 나타냈다. As it is not allowed to landfill sludge from 2001 by the act of waste management, new systems of treating sludge are necessary. Life Cycle Assessment, LCA, is a method for evaluating systems in the aspect of environment and also can apply to decision making tools for policy making. The objective of this study is to assess 3 alternatives of landfill: incineration, composting, solidification by applying LCA. This study is done with operation data from incinerator in Kuri, composting facility in Nanjido, solidification facility in Kimpo and electricity and transport data of Korea in 1998 are used. The results of the LCA is that the composting system is most environmental-friendly and the solidification system is least environmental-friendly.