해조가 2,4,6-trinitrobenzene-sulfonic acid로 유발된 염증성 장질환 동물모델에 미치는 영향

이상욱,류봉하,박재우,Lee, Sang-Wook,Ryu, Bong-Ha,Park, Jae-Woo 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.2

Objectives : The aim of the current study was to investigate the effects of Sargassum (Sargassum pallidum (TURN.) C. AG.; SP) on the experimental colitis induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS) in mice. Methods : ICR mice were divided into 7 groups (NOR, CON, $SS50\times5$, $SP20\times3$, $SP50\times3$, $SP20\times5$, $SP50\times5$). TNBS processing was intrarectally applied to all experimental groups on the 3rd experiment day, except the normal group (NOR). For investigating the prophylactic effect, SP at doses of 20 mg/kg ($SP20\times5$) and 50 mg/kg ($SP50\times5$) were orally administered for 5 days. The SP at doses of 20 mg/kg ($SP20\times3$) and 50 mg/kg ($SP50\times3$) were orally administered for 3 days after the colitis induction in order to check the effect of treatment. As a positive control group, sulfasalazine 50 mg/kg ($SS50\times5$) was administrated. Macroscopic findings of epithelial tissue on mice were measured by colon length and macroscopic score. Histologic findings were also checked by crypt cell, epithelial cell, inflammatory cell and edema of submucosa. We measured the ability of SP to inhibit lipid peroxidation and myeloperoxidase activity. We also measured levels of the inflammatory markers, interleukin (IL)-$1\beta$ and cyclooxygenase-2 (COX-2), its transcription factor activation, phospho-NF-${\kappa}B$ (pp65), in the colon by enzyme-linked immunosorbent assay and immunoblot analysis. We measured activation of fecal bacterial enzyme, $\beta$-glucuronidase and degradation activation of fecal glycosaminoglycan (GAG), and hyaluronic acid. Results : Oral administration of SP on mice inhibited TNBS-induced colon shortening and myeloperoxidase activity in the colon of mice as well as IL-$1\beta$ and COX-2 expression. SP also inhibited TNBS-induced lipid peroxidation and pp65 activation in the colon of mice. SP inhibited $\beta$-glucuronidase activation and fecal hyaluronic acid degradation activation as well. Conclusions : SP could be a possible herbal candidate and preventive prebiotic agent for treating inflammatory bowel disease (IBD). Further experiments to differentiate effects of SP on IBD, such as other solutions and extracting times, might be promising.

2-2형 압전복합재료의 전기적 특성

이상욱,남효덕,류정탁,김연보,Lee, Sang-Wook,Nam, Hyo-Duk,Ryu, Jeong-Tag,Kim, Yeon-Bo 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.8

We have investigated on the development of 2-2 mode piezocomposites that have better piezoelectric activity and lower acoustic impedance than those of conventional piezoceramics. In this study, we have investigated the electrical properties and acoustic impedance of 2-2 mode piezocomposite which were fabricated using the dice-and-fill technique for the different volume fractions of PZT The volume shrinkage of polymer is an important factor in 2-2 mode piezocomposites fabrication. The thickness mode electromechanical coupling factor($\kappa_t$) of PZT was compared with that of piezocomposites. It was shown that the 2-2 mode piezocomposites were much better than the PZT only. The acoustic impedance of 2-2 mode piezocomposites decreased linearly when PZT volume fraction was decreased.

도이치말에서의 부정유형에 대하여

이상욱,Lee Sang-Wook 한국독어학회 2000 독어학 Vol.2 No.-

Die Negation im Deutschen wird in der Tradition, besonders aus dem syntaktischen Aspekt, in zwei verschiedenen Arten unterschieden: Sondemegation(Wortnegation oder Konstituentennegation) vs. Satznegation. Demzufolge bei der Satznegation bezieht sich das Negationswort auf die gesamte Aussage, d.h. die vom gesamten Satz $ausgedr\"{u}ckten$ Propositionskomplexe und bei der Sondernegation auf Teile des gesamten Satzes. Diese Unterscheidung wird hauptsachlich durch die Stellungsmoglichkeiten von 'nicht' $begr\"{u}ndet$. Sie wird aus kommunikativ orientierten Aspekten problematisiert. Solche $Ans\"{a}tze$ gehen davon aus, $da{\ss}$ die Negation eine Blockierungsoperation bei der Bearbeitung bereits vorhandener Kenntnisse ist. Aus kommunikativ orientierten Aspekten wird nur bei der Satznegation von 'Negierung' gesprochen, und bei der Sondernegation liegt nur eine negierte Teilstruktur vor, die den Chakrakter der Affirmierung des Gesamtsatzes zwar modifiziert, aber nicht aufhebt. Als $vorla\"{u}figes$ Fazit stellt man fest, $da{\ss}$ die Beschreibung der Negation aus kommunikativ-pragmatischen Sichten die Unterscheidung Satznegation/Sondernegation nicht $\"{u}berfl\"{u}ssig$ macht. Um die Negation besser zu ermitteln, werden nicht nur unterschiedliche syntaktische $Stellungsm\"{o}glichkeiten$ von 'nicht' $ber\"{u}cksichtigen$, sondern auch die im Satz verschieden gegebene Intonation und auch kommunikative $Handlungszusammenh\"{a}nge$.

언어행위적 관점에서 본 부정문의 기능들

이상욱,Lee Sang-Wook 한국독어학회 1999 독어학 Vol.1 No.-

In den kommunikativen orientierten Sprechbehandlungen lassen sich negative $S\"{a}tze$ allgemein als Klasse kommunikativer Operlationen mit spezifischen kommunikativ-pragmatischen Funktionen kennzeichnen. Diese Funktionen, die der Sprecher mit den sogenannten negativen $Behauptungss\"{a}tzen$ in wirklichen kommunikativen Sprechakten $ausdr\"{u}ckt$, stellen dabei Handlungs-bzw. Sprechhandlungsintentionen des Sprechers dar. Sie $k\"{o}nnen$ aus den in negierten $\"{A}u{\ss}erungen$ implizierten Sprecher-Einstellungen zu bestimmten Sachverhalten, die in den vorangehenden $\"{A}u{\ss}erungen\;seines\;Gespr\"{a}chpartners\;ausgedr\"{u}ckt$ werden, abgeleitet werden. In diesem Zusammenhang sind die negativen $Behauptungss\"{a}tze$ erst dann sinnvoll darzustellen, wenn sie mit Voraussetzungsstruktur verbunnden werden. D.h. also die Funktionen der negativen $Behauptungss\"{a}tze\;k\"{o}nnen$ im Zusammenhang mit einer(bzw. mehreren) vorangehenden $\"{A}u{\ss}erung(en)\;des\;Gepr\"{a}chpartners$ oder den aktuellen $Sprechhandlungsumst\"{a}nden\;besser\;erkl\"{a}rt$ werden. Aus solchen kommunikativen Situationen kann man bestimmte Einstellungen des $Gespr\"{a}chspartners$ annehmen. So haben wir negative $Behauptungss\"{a}tze$, die mit den in Grammatiken angenommenen verschiedenen $Negationsw\"{o}rtern$ verwirklicht werden, in die Subkategorie der Sprechhandlungen eingesetzt, um ihre sinnvollen Funktionen zu bezeichnen. Dabei stellen wir fest $da\ss$ den negativen $Behauptungss\"{a}tzen$ nicht nur eine Sprechhandlung 'Verneinen' zuzuordnen ist. In den aktuellen Sprechhandlungen zeigen sie auch die anderen kommunikativ-pragmatisch orientierten Funktionen. Wir klassifizieren nun die folgenden illokutionaren Typen: 1) Verneinen(bzw. Negieren); 2) Widersprechen; 3) $Pr\"{a}zisieren$ (oder Korrigier); 4) Behaupten; 5) Antworten auf Wortfrage; 6) Zustimmen; 7) Verweigern

특징 기반 다중 물체 추적 시스템에 관한 연구

이상욱,설성욱,남기곤,권태하,Lee, Sang-Wook,Seol, Sung-Wook,Nam, Ki-Gon,Kwon, Tae-Ha 대한전자공학회 1999 電子工學會論文誌, S Vol.s36 No.11

본 논문은 연속 영상에서 윤곽선과 특징을 이용하여 주위 환경 변화에 적응가능한 다중 물체 추적 방법을 제안한다. 적응 배경 모델을 사용하여 주위 환경 변화에 적응케 했으며, 물체 분할 모델은 배경 영상과 현재 영상의 차영상에서 국부 영상의 임계값 이상의 화소를 찾아 연결한 영역을 추출한다. 특징 추출과 물체인식모델은 탐색 창 내에서 발견된 다중 물체의 데이터 연상 문제를 해결하기 우해 사용되며, 실시간 추적을 위해 칼만 필터를 사용하였다. 제안된 방법을 도로 영상에 적용한 결과 다중 차량 추적이 정확히 이루어짐을 실험을 통해 보였다. In this paper, we propose an adaptive method of tracking multiple moving objects using contour and features in surrounding conditions. We use an adaptive background model for robust processing in surrounding conditions. Object segmentation model detects pixels thresholded from local difference image between background and current image and extracts connected regions. Data association problem is solved by using feature extraction and object recognition model in searching window. We use Kalman filters for real-time tracking. The results of simulation show that the proposed method is good for tracking multiple moving objects in highway image sequences.

반작용 휠 외란의 시야선 안정성 영향

이상욱,김동훈,전동익,오화석,김응현,김규선,Lee, Sang-Wook,Kim, Dong-Hoon,Cheon, Dong-Ik,Oh, Hwa-Suk,Kim, Eung-Hyun,Kim, Gyu-Sun 항공우주시스템공학회 2008 항공우주시스템공학회지 Vol.2 No.1

The line of sight(LOS) is affected by the vibration of spacecraft. It is necessary to predict the effect of disturbance on LOS stability. Reaction wheel assembly is anticipated to be the largest disturbance source on spacecraft. The disturbance which is occurred mainly due to the mass imbalance is analyzed with harmonic numbers. The accuracy and stability are verified by probability density function with dynamic equation of the satellite motion.

편측 종골 골절의 수술적 치료의 예후 관련 인자

이상욱,고상봉,이현섭,Lee, Sang-Wook,Ko, Sang-Bong,Lee, Hyun-Sub 대한족부족관절학회 2006 대한족부족관절학회지 Vol.10 No.2

Purpose: To study prognostic factors of unilateral calcaneus fracture underwent surgery. Materials and Methods: We selected appropriate 60 cases of 236 calcaneus fracture cases between March 1985 and March 2004, and analyzed the correlation between sex, age, smoking, injury mechanism, Essex-Lopresti classification of calcaneus fracture, preoperative Bohler angle, postoperative Bohler angle, postoperative 1 year Bohler angle and Visual Analogue Scale (VAS), P.S. Kerr's Calcaneal Fracture Score (CFSS). The average age was 41.4 and average follow up period was 74 (12 to 240) months. Results: For follow up period, average VAS is 3.43 and CFSS is 81.23. The sex, age, smoking, injury mechanism, and preoperative, postoperative, postoperative 1 year Bohler angle had no correlation with the prognosis. But the Essex-Lopresti classification of calcaneus fracture, tongue type had better prognosis than joint depression type (VAS : p=0.041, CFSS : p=0.021). Conclusion: In unilateral calcaneus fracture, the sex, age, smoking, injury mechanism, preoperative Bohler angle, postoperative Bohler angle, postoperative 1 year Bohler angle had no correlation with the prognosis of fracture, but in Essex-Lopresti classification, the tongue type fracture had better prognosis than the joint depression type.

동적 XML 조각 스트림에 대한 메모리 효율적 질의 처리

이상욱,김진,강현철,Lee, Sang-Wook,Kim, Jin,Kang, Hyun-Chul 한국정보처리학회 2008 정보처리학회논문지D Vol.15 No.1

본 논문은 메모리 용량이 제약되어 있는 이동 단말기에서의 XML 데이터에 대한 질의 처리 기술에 관한 것이다. 대량의 XML 데이터에 대한 질의를 메모리 용량이 크지 않은 단말기에서 처리하는 경우 XML 데이터를 XML 조각(fragment)으로 분할하여 스트림으로 전송하고 처리하는 기술이 필요하다. 이는 전체 XML 문서를 재구성하지 않고 XML 데이터에 대한 질의 처리를 가능하게 한다. XFrag[4], XFPro[5], XFLab[6] 등 기존에 제시된 기법들은 질의 처리를 위해 조각에 대한 정보를 저장하고 사용한 후 더 이상 불필요해진 것들을 식별하여 삭제하지 못하기 때문에 조각 정보가 메모리에 계속 누적되어 대용량의 XML 데이터에 대해 질의 처리를 수행하기에는 문서 크기에 따른 확장성(scalability)이 떨어진다. 특히, XML 조각이 동적으로 생성되어 무한정 스트리밍되는 경우에 한정된 메모리로는 질의 처리를 보장할 수 없다. 본 논문에서는 동적 XML 조각 스트림에 대한 질의 처리에 있어 문서 크기에 따른 확장성 있는 질의 처리를 수행하기 위하여 누적된 조각 정보 삭제 기법들을 제시하고 이들을 바탕으로 기존 기법의 확장을 제시한다. 구현 및 성능 실험 결과 본 논문에서 확장된 기법이 기존의 기법보다 메모리 효율성이 현저히 높고 문서 크기에 따른 확장성이 월등히 우수한 것으로 나타났다. This paper is on query processing in the mobile devices where memory capacity is limited. In case that a query against a large volume of XML data is processed in such a mobile device, techniques of fragmenting the XML data into chunks and of streaming and processing them are required. Such techniques make it possible to process queries without materializing the XML data in its entirety. The previous schemes such as XFrag[4], XFPro[5], XFLab[6] are not scalable with respect to the increase of the size of the XML data because they lack proper memory management capability. After some information on XML fragments necessary for query processing is stored, it is not deleted even after it becomes of no use. As such, when the XML fragments are dynamically generated and infinitely streamed, there could be no guarantee of normal completion of query processing. In this paper, we address scalability of query processing over dynamic XML fragment stream, proposing techniques of deleting information on XML fragments accumulated during query processing in order to extend the previous schemes. The performance experiments through implementation showed that our extended schemes considerably outperformed the previous ones in memory efficiency and scalability with respect to the size of the XML data.

족부에 발생한 내혈관 유두내피 증식증(1예 보고)

이상욱,장호진,김석준,Lee, Sang-Wook,Chang, Ho-Jin,Kim, Seok-Jun 대한족부족관절학회 2012 대한족부족관절학회지 Vol.16 No.4

Intravascular papillary endothelial hyperplasia (IPEH) known as Masson's hemangioma is a rare benign reactive vascular lesion caused by the abnormal proliferation of endothelial cells. The lesion occurs most commonly in the fingers, head and neck, but very rare in the foot. We report a case of IPEH in the foot treated with operative excision.

모바일 환경을 위한 맞춤형 서비스 유비쿼터스 영상전송 시스템의 설계

이상욱,안용범,김응수,Lee, Sang-Wook,Ahn, Yong-Beom,Kim, Eung-Soo 한국정보통신학회 2008 한국정보통신학회논문지 Vol.12 No.4

영상전송에 있어서 주변 환경에 대한 영상인식은 대단히 중요하다. 최근 정보인프라의 대중화에 따라 모바일 환경에까지 유, 무선을 통한 대상의 상태를 영상으로 확인하려는 사용자 중심적 욕구가 증가하였다. 하지만 기존의 모바일용 솔루션은 저대역폭을 가지는 모바일 단말기 기반의 네트워크 특성상 소프트웨어 코덱만을 지원함으로써 소프트웨어적인 처리의 한계로 인한 고화질의 영상은 기대 할 수 없었다. 이러한 단점을 해결하기 위해서 본 논문에서는 모바일 환경에서 적용할 수 있는 고화질 지원과 실시간적 요소를 고려하여 높은 압축률을 가지는 국제비디오 압축 표준인 MPEG-4 기반 하드웨어 코덱 설계에 관하여 기술하였다. 이를 위한 시스템의 최적화된 설계를 위하여 임베디드용 전용 CPU를 채용하였으며 구현된 시스템은 모바일 환경에서도 고기능을 서비스하고 전송속도 및 해상도 등에 있어서 우수한 성능을 나타내었다. An image recognition for surrounding conditions is very important in image transmission. In recently rears, as the information infrastructure is more general, the user-centered demands in which they want to identify by object's states image using wire or wireless environment have increased. However, existing mobile solution could be hard to expect high quality mage, because limitation of software processing according as network based on mobile terminal which has low band width supports software codec. To solve this weak point, this paper describes on hardware codec design based on MPEG-4 which is international video compression standard. Implemented system contains the embedded CPU for optimized design and it works high quality service as transmission speed and resolution in mobile circumstance.