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심성용,Sim, Sung-Yong 대한한방안이비인후피부과학회 2015 한방안이비인후피부과학회지 Vol.28 No.4
Objective : The patient presented with a week history of orange-eryhtematous follicular hyperkeratotic papules in facial and skull part.Methods : Korean medicinePalMul-tang八物湯 was used and Aroma ointment and Retinoid lotion were used together.Results : After 6 months therapy, she experienced remarkable improvement of symptoms.Conclusions : Pityriasis Rubra Pilaris (PRP) is belong to 'Pityriasis Rubra Pilaris (PRP) is belong to 'Honyoja狐尿刺'in Korean medicine, and we can expect a relatively good treatment effect.
심성용,김경태,엄유식,남혜정,김경준,Sim Sung-yong,Kim Kyung-tae,Um Yu-sik,Nam Hae-jeong,Kim Kyung-jun 대한한의진단학회 2004 大韓韓醫診斷學會誌 Vol.17 No.2
Vertigo is a symptom, not a disease. The tenn vertigo refers to the sensation of spinning or whirling that occurs as a result of a disturbance in balance. It's sometimes referred to as a hallucination of motion. The cause of vertigo is very various and generally divided into peripheral and central. A patient presented with severe vertigo, nystagmus and heteophoria. She has taken the BanHaBaekChulChunMa-tang and treated by acupuncture. After 2 days, her symptoms become disappeared and about 1 week, all symptoms except heterophoria were disapperaed. And after 2 weeks, heterophoria was disappeared. In conclusion, we diagnosed her case as vestbular neuronitis by her clinical course, but we also considered her illness as vertebrobasilar insufficiency, TIA etc.
加味柱枝湯이 알레르기 비염에 미치는 영향에 관한 실험적 연구
심성용,김경준,Sim Sung-yong,Kim Kyung-jun 大韓外官科學會 2004 大韓外官科學會誌 Vol.15 No.1
Major symptoms of allergic rhinitis are nasal obstructions, sneezing and watery rhinorrhea. Gamigyeji-tang has been used to treat for watery rhinorrhea, which is one of the symptoms of allergic rhinitis. This experimental study was done to rescarch effects of Gamigyeji-tang. We have studied effect of mice on OVA-induced Production of IL-4, IL-5, IFN-${\gamma}$ by Murine Splenocytes, and effect of OVA-induced total IgE and OVA-Specific IgE. The results were as follows ; 1. In IL-4 study, Gamigyeji-tang treated group was proved significant inhibitory effect(p〈0.005) 2. In IL-5 study, Gamigyeji-tang treated group was proved significant inhibitory effect.(p〈0.05) 3. In IFN-${\gamma}$ study, Gamigyeji-tang treated group was proved significant inhibitory effect(p〈0.000001) 4. In Total IgE, Gamigyeji-tang treated group didn't showed significant inhibitory effect. 5. In OVA-specific IgE, Gamigyeji-tang treated group didn't showed significant inhibitory effect. According to this result, Gamigyejj-tang was concluded to be effective on anti-allergic action. More studies are required to investigate the mechanism of inhibition by herbal medicine in allergic rhinitis model.
Antiinflammatory and antioxidative effects of Agrimonia pilosa Ledeb
심성용,Kim GJ,Ko SG 경희대학교 융합한의과학연구소 2007 Oriental Pharmacy and Experimental Medicine Vol.7 No.3
Agrimonia pilosa Ledeb. has long been used for a useful natural agent ameliorating inflammation related symptoms in the folk medicine recipe. This study was performed to investigate effects of Agrimonia pilosa Ledeb.(AP) on the expression of inflammation related genes such as the inducible nitric oxide synthase (iNOS) in macrophage cell line, RAW 264.7 cells. The AP (whole plants) was extracted with 80% ethanol and sequentially partitioned with solvents in order to increase polarity. Among the various solvent extracts of AP, the n-butanol (BuOH) fraction showed the most powerful inhibitory ability against nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 cells without affecting cell viability. Reverse transcriptase-polymerase chain reaction and Western blot analysis revealed that the BuOH fraction provided a primary inhibitor of the iNOS protein and mRNA expression in LPS-induced RAW 264.7 cells. The DPPH and OH radical scavenging activities of the several fractions of 80% ethanol extracts of AP significantly increased by EtOAC and BuOH fractions. Thus, the present study suggests that the response of a component of the BuOH fraction to NO generation via iNOS expression provide an important clue to elucidate anti-inflammatory mechanism of AP.
심성용,이원욱,박진우,오차환 한국물리학회 2021 Current Applied Physics Vol.28 No.-
Helium (He) inductively coupled plasma (ICP) was generated by a right-helical-type RF antenna. At a fixed He pressure of 20 mTorr, the optical emission spectrum from the He plasma was measured with RF power. The E-H mode transition and the characteristic hysteresis of the mode transition were confirmed by a change in the spectral line intensity of the 33D 23P transition at 587.6 nm. By laser absorption spectroscopy using a laser light with a wavelength of 1083 nm resonant to the 23S→23P absorption transition, the line-integrated He 23S metastable density was measured and found to show consistent behavior with the spectral line intensity of the 33D 23P transition during the E-H mode transition. The line-integrated He 23S metastable atom density exhibited distinctly different longitudinal distributions in the E and H modes.
안면마비를 동반한 Tolosa-Hunt Syndrome 환자 1례
심성용,엄유식,홍철희,김경준,변학성,Sim, Sung-Yong,Um, Yu-Sik,Hong, Chul-Hee,Kim, Kyung-Jun,Byun, Hak-Sung 대한한방안이비인후피부과학회 2005 한방안이비인후피부과학회지 Vol.18 No.2
Painful ophthalmoplegia due to idiopathic granulomatous inflammation of the cavernous sinus/superior orbital fissure has been termed Tolosa-Hunt syndrome(THS). The syndrome is characterized by pain behind, above or around the eye, involvement of the cranial nerves which pass through the cavernous sinus, spontaneous remissions and exacerbations, and a favourable response to steroid therapy. There was the 56 years old man who suffered from painful ophthalmoplegia and facial palsy. The oriental medical treatment without steroids and analgesics reduced the symptoms of the patient remarkably during 5 weeks. There is few report that treat THS with oriental medical method. If more clinical trials like this are proved to be effective, we can expect that oriental medical treatment will be a good method in THS.