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      • KCI우수등재

        고령자 주간 통행의 공간분포 패턴과 영향 요인 : 성별에 따른 차이를 중심으로

        서형주,박인권 대한국토·도시계획학회 2023 國土計劃 Vol.58 No.7

        본 연구는 은퇴 후 여가 시간이 많을 것으로 예상되는 연령층인 70세 이상의 고령자가 낮시간 동안어느 지역으로 밀집하여 이동하는지, 유출입 이동 흐름에 어떠한패턴이 존재하는지, 그리고 이러한 노인 통행을 유발하는 지역요인에 성별에 따른 차이가 존재하는지를 규명하고자 한다. 그과정에서 고령자의 내·외재적 욕구 충족을 통한 웰빙 증진이라는고령자 통행의 특수성과 성별 차이를 고려하여 모형을 구축·해석하고자 한다. 이를 위해 2021년 생활이동빅데이터를 활용하여, 서울대도시권 고령자의 주간이동 밀집 지역의 공간적 분포 특성과 이동 패턴을 파악하고, 성별에 따라 고령자들이 선호하는 시설이나 서비스 등 목적지의 지역 환경 요인들이 고령자의 주간 통행에 미치는 영향의 차이를 공간 SUR(spatial seemingly unrelated regression) 모형을 통해 분석하였다. 특히, 고령층은 타연령대에 비해 장거리 이동 비율이 높기에(추상호 외, 2013), 서울 인근 외곽지역으로의 넓은 이동 반경을 가진 고령자의 이동 특성을 반영하여 수도권 전역을 대상으로 통행 패턴을 분석하였다. This study is intended to investigate the travel patterns of individuals aged 70 and above, who are expected to have a significant amount of leisure time after retirement, and to identify the urban-environmental factors that influence elderly mobility, with a focus on gender differences. Spatial SUR (Seemingly Unrelated Regression) model analysis was conducted using mobile phone location-based OD (Origin-Destination) big data. The analysis reveals that older adults engage in active mobility, seeking to fulfill their needs and overcome personal deficiencies, while actively participating in social interactions and community engagement during their increased leisure time. Furthermore, differences in spatial distribution patterns and influencing factors are observed between genders. Female older adults tend to travel within their local neighborhoods and frequent traditional markets, while male older adults primarily engage in long-distance travel and frequent urban parks. Among urban spaces, coffee shops, “colatecs,” and dance schools are characterized by gender-inclusive usage patterns. However, public welfare facilities such as seniors’ centers and elderly classrooms have encountered resistance. When designing age-friendly cities for the ultra-aged society, careful consideration of gender is necessary to create urban spaces that fulfill the social participation needs of older adults and enable them to spend their daily lives vibrantly.

      • KCI등재후보

        멍게의 수압수용체세포 형성에서 FGF와 MEK 신호의 역할

        서형주,김길중 한국발생생물학회 2009 발생과 생식 Vol.13 No.4

        멍게 유생의 뇌포에는 2개의 감각색소세포인 평형기와 안점 이외에 또 다른 감각세포로 추정되는 수압수용체세포가 존재한다. 수압수용체세포 형성에 관해서는 현재까지 거의 알려진 것이 없다. 본 연구에서는 수압수용체세포 형성에서 FGF 신호전달 과정의 관련성을 조사했다. 수정란에 Hr-FGF9/16/20 antisense MO를 미세주입했을 때, 발생한 유생에서 수압수용체세포 특이적 Hpr-1 항원의 발현이 검출되지 않았다. 32세포기부터 FGF 수용체 억제제 SU5402 및 MEK 억제제 U0126을 처리한 배아도 수압수용체세포를 갖지 못한 유생으로 발생했다. 다음으로 수압수용체세포 형성에 FGF 신호전달 과정이 관련되는 시기를 자세히 조사했다. 수압수용체세포 형성에는 FGF 수용체 활성이 16세포기부터 64세포기까지 필요하다는 것이 시사되었다. U0126은 8세포기부터 후기 낭배기까지 Hpr-1 항원 발현을 억제했다. Hpr-1 항원 발현은 신경판기 직전부터 U0126의 영향을 받지 않았다. 따라서, 멍게에서 수압수용체세포 형성은 1차 신경유도기부터 후기 낭배기까지 FGF 신호전달 과정을 필요로 한다는 것이 밝혀졌다.

      • KCI등재

        Weight Reduction Effect of Angook Cereal Mixture on Female College Students

        서형주,김영순,정은영,장은재,오성훈 한국식품영양과학회 2006 Preventive Nutrition and Food Science Vol.11 No.3

        This study evaluated the weight reduction effect of Angook cereal mixture. The cereal mixture was prepared with barley, unpolished rice, corn, soybean, Garcinia cambogia, guar-gum, maltodextrin, glucomannan and a vitamin mixture. Eighteen female college students participated in this 8 weeks weight control program. All subjects were randomly assigned to the treatment and placebo groups. Mean energy intake of the treatment group was 1,356.4±79.9 kcal (carbohydrate: 67.1%, protein: 18.7%, fat: 14.2%) and placebo group consumed 1,367.6±71.8 kcal (carbohydrate: 64.2%, protein: 19.7%, fat: 16.1%) during program. The placebo group lost 3.9±0.8 kg of body weight and the treatment group lost 5.9±0.7 kg of body weight. There were significant differences in the decrease of total body weight, absolute fat mass, waist circumference (WC) and hip circumference (HC) between the two groups (p<0.05), however, the lean body mass was not significantly decreased in the treatment group compared to the placebo group. There were no differences in the changes in blood glucose, total-cholesterol, HDL-choloesterol, LDL-cholesterol and triglycerides between groups. These findings suggest that the intake of Angook cereal mixture may be beneficial for the reduction of the body weight, absolute fat mass, WC and HC.

      • Rhodococcus 속이 생산하는 Nitrile Hydratase의 특성

        서형주 高麗大學校 倂設 保健大學 保健科學硏究所 1993 保健科學論集 Vol.19 No.1

        Nitrile hydratase(NHase) from Rhodococcus sp. was purified by 3 succesive column chromatogra-phy, TMAE-cellulose, Toyopeari HW-65, and Hydroxyapitite chromatography. The enzyme have been purified about 54.5 folds with yield of 6.7%. The enzyme had a molecular weight of approximately 60 KDa and consisted of 2 subunits each having molecular weight of 28.5 and 29 KDa. The enzyme was most stable in the temperature region of 0∼35℃, and lost its activity above 40℃. The enzyme was most stable in the pH reigion of 6∼8. The optimum temperature and pH for the enzyme activity was 30˚C and 8.0, respectively. The enzyme showed wide substrate specificity, and most of the metal ions did not affect enzyme activity significantly.

      • 양파 가수분해물의 갈색화에 대한 저장조건의 영향

        서형주,유광원 高麗大學校 倂設 保健大學 保健科學硏究所 1997 保建科學硏究論集 Vol.6 No.1

        Onion hydrolysate prepared with celluclast 1.5L and pectinex showed characteristics as follows ; 86% of D.H.(Degree of Hydrolysis), 54 ㎎/㎖ of total sugar, 31 ㎎/㎖ of reducing sugar, 48 ㎎/㎖ of phenols, and 83% of yield. Onion hydrolysate was processed browning reaction during storage. Browning reaction was rapidly processed under alkali condition. But changes of phenols content was showed an opposite trends of brewing degree. Browning degree was increased with decreasing concentrate degree(below 60 brix) and increasing storage temperature. And phenols content was a same trends of browning degree according to concentrate degree and storage temperature. On the contrary, browning reaction was slowly processed under neutral pH(pH 5.2-7.0), high concentrate degree(above 60 brix) and low storage temperature. Brewing degree(absorbance at 420 ㎚) was 0.352 at early storage time for 37℃ and was 0.481 at 7 days storage. Browning degree was increased with increasing storage time.

      • 두류 및 고추류의 단백분해효소 안정성

        서형주,김경미,김영순 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保建科學硏究論集 Vol.8 No.1

        Protease activities were measured in beans and green peppers used as cooking material or a side dish. Protease in yellow soybean and black soybean were high activities (255 unit and 186 unit, respectively) among soybeans and green papers. Kwari pepper that had highest activity of protease among green peppers showed 58 unit of protease activity. After dialysis, remaining activities of soybeans and green peppers were 67-77% and 22-63%, respectively. Remaining activities in yellow soybean, black soybean, mungbean and small red bean were 82%, 77%, 72% and 67%, respectively. And those in green pepper, Kwari pepper and Chungyang pepper were 63%, 55% and 23%, respectively. In the result of thawing after freezing the proteases, remaining activities in beans and green peppers were 75-100% and 45-82%, respectively. The protease activities in beans and green peppers were decreasing with increasing heating time at 60℃. After 10 min of heat treatment, the activities were sharply decreased. Proteolytic effects in beans and green peppers on plant protein sources (soytone and malt extract) were higher than animal protein sources (collagen, elastin, fibrin, casein and gelatin). Those on collagen and elastin were higher than the others of animal protein sources.

      • 고추장의 혈압강하 효과

        서형주,정수현,유광원,손흥수 高麗大學校 倂設 保健大學 保健科學硏究所 1997 保健科學論集 Vol.23 No.1

        This study was to evaluate the inhibitory effect of Kochujang prepared with Asp. oryzae on angiotensin converting enzyme(ACE). Kochujang had some characteristics follow as ; pH 4.7, 9.46 of acidity, 23.9% of reducing sugar, 152㎎% of amino-N and 0.839(hot water extract) and 3.460(ethanol extract) of absorbance at 500 nm. Methanol extract of Kochujang was a high inhibitory effect on ACE. And IC_(50) of mathanol extract was 1.15 mg. Methanol extract was fractionated with various solvents, ethylacetate(F-EA), butanol(F-B) and water(F-D). F-B and F-EA was obtained from methanol extract had a high ihibitory effect on ACE. F-B fraction was showed the competitive inhibition and F-EA was uncompetitive inhibition on ACE.

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