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박재정 ( Jae Jung Park ),정성애 ( Sung Ae Jung ),노영욱 ( Young Wook Noh ),강민정 ( Min Jung Kang ),정지민 ( Ji Min Jung ),김성은 ( Seong Eun Kim ),정혜경 ( Hye Kyung Jung ),심기남 ( Ki Nam Shim ),김태헌 ( Tae Hun Kim ),유권 ( Kw 대한소화기학회 2010 대한소화기학회지 Vol.55 No.4
목적: 염증성 장질환에서 골밀도 감소는 비교적 흔한 합병증이며 이와 연관된 위험인자들이 보고되고 있으나, 한국의 염증성 장질환 환자에서의 연구는 미미하다. 본 연구는 염증성 장질환 환자에서의 골밀도 감소의 유병률 및 위험인자를 알아보고자 하였다. 대상 및 방법: 30명의 염증성 장질환 환자를 대상으로 X-선 골밀도 측정기에 의해 골밀도를 측정하였다. 혈청 인, 칼슘, 오스테오칼신과 데옥시피리디놀린을 포함한 인자들을 측정하였다. 의무기록을 후향적으로 검토하여 질병의 유병기간, 활성도, 약물력, 체질량지수 등을 조사하고 골감소와의 연관성을 분석하였다. 결과: 전체 환자의 63.3%에서 골밀도 감소가 있었으며 크론병과 궤양성 대장염에서의 유의한 차이는 없었다. 골밀도 감소와 임상적 지표들 간의 유의한 연관성이 없었고, 골대사의 지표들과 골밀도 사이에 유의한 상관관계가 없었다. 골밀도검사 전 글루코코르티코이드를 사용하지 않았던 염증성 장질환 환자의 50.0%에서 골밀도 감소를 보였다. 결론: 한국의 염증성 장질환 환자에서도 서구와 마찬가지로 골밀도 감소가 빈번하며, 이러한 골감소의 원인은 명확하지는 않지만 다양한 인자들이 복합적으로 관여할 것으로 여겨진다. 따라서, 글루코코르티코이드 사용 여부와 상관없이 염증성 장질환 환자에서 골밀도 측정이 필요하다. Background/Aims: Several clinical risk factors for low bone mineral density (BMD) in the patients with inflammatory bowel disease (IBD) have been suggested. However, its prevalence and pathophysiology in Korean population have not been fully studied. The aim of this study was to investigate the prevalence and risk factors for low BMD in Korean IBD patient. Methods: BMD of the lumbar spine and femur was evaluated using dual-energy X-ray absorptiometry in 30 patients with IBD. Biochemical parameters of bone metabolism, such as serum calcium, phosphorus, osteocalcin, and deoxypyridinoline were measured. The associations between low BMD and clinical parameters such as disease duration, disease activity, drug history, body mass index (BMI), and others were evaluated retrospectively using medical records. Results: Low BMD at the lumbar spine or femur was observed in 63.3% of the patients, and there was no significant difference between the patients with Crohn`s disease and ulcerative colitis. Clinical and biochemical parameters were irrelevant to BMD. In the patients without glucocorticoid treatment prior to BMD measurement, already 50.0% of patients had low BMD. Conclusions: Low BMD is a common feature in Korean IBD patients, even those who do not use glucocorticoid. The multiple factors may be involved in the pathogenesis of low BMD. Therefore, BMD should be examined in all IBD patients, irrespective of glucocorticoid treatment. (Korean J Gastroenterol 2010;55:237-244)
박재정(Park Jae-Jung) 충남대학교 사회과학연구소 2000 사회과학연구 Vol.11 No.-
1970년대 초반까지 전형적인 대도시형 투표행태를 보여주었던 대전은 1987년 대통령직선제가 부활되면서 지역주의적 정치동원의 한 축을 형성하였다. 신민주공화당(자민련)이 단독으로 참여한 최근까지의 6차례 선거 분석 결과, 대전은 같은 대도시인 부산이나 광주에 비하여 총유동성과 지역유동성이 월등하게 높아서 지역정당에 대한 투표응집력이 상대적으로 낮으며, 유권자들이 지역정당을 넘나드는 투표 행태를 보이고 있음이 입증되었다. 그럼에도 불구하고 5차례의 선거유동성(6차례의 선거) 분석 결과, 제16대 총선을 제외한 나머지 선거는 비경쟁적이거나 지역블록내 경쟁으로 나타났으며, 지역균열구조가 경쟁의 영역이 아닌 정체성의 영역에서 작동하고 있음을 알 수 있었다. 이런 의미에서 제16대 국회의원 선거는 지역블록간 경쟁을 부활시킨 중요한 의미를 가지는 선거였다고 결론지을 수 있다. 다만 제16대 총선 이후 대전지역에서 치러진 두 차례의 구청장 보궐선거는 다시 비경쟁적이고 지역균열이 정체성의 영역에서 배타적으로 작용하는 선거로 회귀하였다고 볼 수 있으나, 평일에 치러진 보궐선거였다는 점에서 아직 속단하기에는 이르다고 할 수 있다. 변화의 전망과 관련하여, 대전은 새로운 유권자의 대거 진입으로 타도시에 비하여 투표패턴이 달라질 가능성이 높으며, 전체적으로는 정당에 대한 친화력의 감소, 높은 선거유동성, 투표율의 감소 등의 현상이 다른 대도시에 비하여 높게 나타남으로써 '정당실패’의 징후가 상대적으로 높은 도시라고 할 수 있다.
박재정 ( Jae Jeong Park ),박진균 ( Jin Gyoon Park ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ),윤숙정 ( Sook Jung Yun ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.1
Ganglion cysts are common lesions that are most often found around the hands and feet. Ganglia around the proximal tibiofibular joint usually occur within the synovial membrane, tendon sheath or peroneal nerve, but they rarely occur within muscle. We report here on a case of a 60-year-old man who complained of an asymptomatic deep seated mass in the proximal part of the right calf that he`d had for more than two years. On magnetic resonance imaging, the lesion appeared as a cystic lesion within the gastrocnemius muscle without communication with the knee joint. To the best of our knowledge, intramuscular ganglion cyst has never been reported in the Korean dermatologic literature. (Korean J Dermatol 2010;48(1):56∼59)
박재정 ( Jae Jung Park ),정성애 ( Sung Ae Jung ),노영욱 ( Young Wook Noh ),김고흔 ( Go Heun Kim ),허현미 ( Hyun Mi Heo ),배서은 ( Suh Eun Bae ),최윤정 ( Yun Jung Choi ),김소이 ( So I Kim ),이명원 ( Myung Won Lee ),강민정 ( Min Jun 대한장연구학회 2009 Intestinal Research Vol.7 No.1
Background/Aims: Primary epiploic appendagitis (PEA) is a rare cause of focal abdominal pain in otherwise healthy patients. Patients with acute abdominal pain are often misdiagnosed clinically as acute appendicitis or diverticulitis. The purpose of this study was to describe the clinical presentation and characteristic computed tomography (CT) findings of PEA. Methods: We reviewed the clinical records and CT images of 23 consecutive patients in Korea who presented with acute abdominal pain between January 2005 and February 2009 and had radiologic signs of PEA. Results: Twenty-three patients (7 females and 16 males; average age, 42±14 years) were diagnosed with symptomatic PEA. Abdominal pain localized to the left (8 patients [44.5%]) and right (10 patients [55.5%]) lower quadrants as the leading symptom. CT findings specific for PEA were present in all patients except one. The symptoms resolved within 1 week (mean, 3.5 days) with or without antibiotic treatment. Conclusions: In patients with localized, sharp, acute abdominal pain not associated with other symptoms, such as nausea, vomiting, fever or atypical laboratory values, the diagnosis of PEA should be considered and the diagnosis confirmed by CT scan. (Intest Res 2009;7:47-51)
박재정 ( Jae Jeong Park ),윤숙정 ( Sook Jung Yun ),이지범 ( Jee Bum Lee ),김성진 ( Seong Jin Kim ),원영호 ( Young Ho Won ),이승철 ( Seung Chul Lee ) 大韓皮膚科學會 2009 대한피부과학회지 Vol.47 No.9
Dermatomyositis is a rare progressive autoimmune disease characterized by inflammatory myopathy that classically manifests several characteristic cutaneous findings, such as Gottron`s papules, periorbital heliotrope rashes, poikiloderma, and reticular telangiectasis. However, there exist a wide variety of atypical cutaneous features in dermatomyositis. We describe a case of bullous DM with preceding adenocarcinoma of the lung in a 62-year old woman. To our knowledge, this is the 2nd report in the Korean literature of a bullous eruption in dermatomyositis. (Korean J Dermatol 2009;47(9):1094∼1097)
Uncommon Acquired Dermal Melanocytosis
박재정 ( Jae Jeong Park ),윤숙정 ( Sook Jung Yun ),김성진 ( Seong Jin Kim ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ),이지범 ( Jee Bum Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.7
Dermal melanocytosis includes a variety of congenital and acquired conditions characterized by a sparse population of intradermal dendritic, variably pigmented, spindle-shaped melanocytes. Mongolian spot, Ota`s and Ito`s nevi are usually present at birth or appear in early childhood. But, several types of acquired dermal melanocytosis that usually appear in adults have been reported. A 47-year-old woman presented with asymptomatic, multiple, symmetric, brownish to black colored macules on the nasal ala, both palms and both feet dorsum that had been there for 10 years. Histopathologic findings showed that some scattered spindle-shaped cells containing melanin pigment in the upper dermis were positive for Fontana-Masson stain and these cells were positive for S-100 protein and MART-1. (Korean J Dermatol 2009;47(7):841~845)
식도를 따라 전이된 부갑상선암에 의한 지속성 부갑상선기능항진증 1예 보고
정파종,박재정,남영수,정원상<SUP>1<,SUP>,Pa Jong Jung,Jae Jeong Park,Young Soo Nam,and Won Sang Chung,<SUP>1<,SUP> 대한갑상선-내분비외과학회 2002 The Koreran journal of Endocrine Surgery Vol.2 No.1
Primary hyperparathyroidism is most commonly caused by an adenoma but rarely by carcinoma of the parathyroid gland. The common clinical manifestations were bone pain, recurrent urinary stone and asymptomatic. Parathyroid carcinoma is different from the parathyroid adenoma in that the invasion to the surrounding tissue or metastasis to the regional lymph nodes and persistent hyperparathyroidism are common in parathyroid carcinoma. It is important that radical en-bloc resection of parathyroidal mass including the lobe of the thyroid that is on the same side and post op follow up is important as well. There is the need of radical surgery even in recurrence of metastatic parathyroid carcinoma for improving hypercalcemia. We experienced a 50-year-old man with primary hyperparathyroidism caused by a parathyroid carcinoma in the left lower parathyroid which was confirmed by histopathologic findings. He was cured by using en-bloc resection of the parathyroid including the left lobe of the thyroid and a left side modifed radical neck dissection. But after 2 months hypercalcemia occurred again and therefore examination with computed tomography, endoscopic ultrasonography and esophagogram revealed a metastasis to the upper and mid esophagus. We opened the chest cavity and resected the surrounding mass of the esophagus. the mass was confirmed to be metastatic tissue from parathyroid carcinoma by histopathologic finding. therefore we report this case. (Korean J Endocrine Surg 2002;2:47-50)
소세포폐암 환자에서 토포테칸 투약 후 발생한 급성호흡곤란증후군
태정현 ( Jung Hyun Tae ),이진화 ( Jin Hwa Lee ),김윤경 ( Yoon Kyung Kim ),심윤수 ( Yun Su Sim ),이경종 ( Kyung Jong Lee ),노영욱 ( Young Wook Noh ),박재정 ( Jae Jung Park ),류연주 ( Yon Ju Ryu ),천은미 ( Eun Mi Chun ),장중현 ( Jun 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.2
Small cell lung cancer is characterized by an aggressive clinical course and a high tendency for early dissemination in spite of a good chemotherapy response. Topotecan is a topoisomerase I inhibitor, and it is used as second-line treatment for small cell lung cancer. The reported dose-limiting adverse reactions to topotecan are mainly hematologic. Yet pulmonary toxicity associated with topotecan is known to be rare. We report here on a case that showed the development of acute respiratory distress syndrome during the 3rd cycle of topotecan chemotherapy in a patient with small cell lung cancer. He developed dyspnea and respiratory failure, and the chest CT scan revealed diffuse ground-glass opacity that was probably due to chemotherapy-related pulmonary toxicity. He finally died of acute respiratory distress syndrome. (Tuberc Respir Dis 2008;65:142-146)