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      • 유아의 성별, 연령에 따른 체력 특성

        전영남,양점홍,김수진,이성민 釜山大學校 附設 體育科學硏究所 2005 體育科學硏究所 論文集 Vol.21 No.2

        The purpose of this study is to examine the characteristics of young children's fitness development in accordance with gheir gender and age, providing information necessary for an effective physical education instruction for young children's growth and development. For the purpose, this researcher selected total 257 young children from K Kindergarten located at K-gu in B Metropolitan City who consisted of 73 boys and 45 girls, both of were fully aged 4, and 83 boys and 56 girls, fully aged 5.......

      • Haemophilus influenzae Type b 에 대한 급성 후두염의 치료 경험 2 례

        이수영(Soo Young Lee),유상호(Sang Ho Yoo),이기선(Ki Sun Lee),홍미애(Mi Ae Hong),김순남(Soon Nam Kim) 대한소아알레르기호흡기학회 1998 소아알레르기 및 호흡기학회지 Vol.8 No.1

        Epiglottitis is an uncommon but potentially life threatening infectious disease in young children. And it is rapidly progressing cellulitis of the epiglottis and adjacent structures that has the potential for causing abrupt, complete airway obstruction. The most common cause of acute epiglottitis is Haemophilius influenzae type b (Hib), therefore in USA, the acute epiglottitis is seen less commonly since the wide spread use of immunization against Hib. In Korea, there has been no report of acute epiglottitis caused by known bacterial organism, and a little investigation of the effects of the immunization against Hib, or Hib related respiratory diseases. In this report, we describe two cases of acute epiglottitis caused by Hib, occurred in non-immunized young-male children admitted to Ajou University Hospital. They had visited to the emergency center of Ajou University hospital with the complaints of acute fever, drooling, dysphagia and severe respiratory difficulties. In both cases, we observed the cherry-red colored, severely swollen epiglottis by the direct laryngoscopic examination. Hib was cultured in blood samples from both two cases, and the patients treated successfully by the 3 days of endotracheal intubation and proper antibiotics therapy without any complications such as pneumonia, meningitis, osteomyelitis, or pericarditis.

      • SCOPUSKCI등재

        만성 B형 간염에서 라미부딘 치료중 발생한 Viral Breakthrough 예의 임상 결과

        안수현,장윤정,오성남,최도원,백수정,정원석,최창원,김경오,임형준,조남영,박종재,김재선,박영태,이명석,연종은,변관수,이창홍 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.4

        목적: 만성 B형 간염의 치료 중 발생하는 약제 내성 변이종은 임상적으로는 치료 중 음전되었던 혈청 HBV DNA가 다시 양전되는 viral breakthrough 로 진단할 수 있다. 현재 약제 내성 변이종이 발생했을 경우라도 라미부딘 치료를 계속 유지하는 것을 권장하고 있으나, viral breakthrough 발생 예들의 장기적 임상경과가 아직도 불명확하여 이것을 일반화하기는 어려운 상황이다. 이에 라미부딘 사용 중 viral breakthrough 가 발생한 예들을 대상으로 그 임상경과를 알아보고자 하였다. 대상과 방법: 9개월 이상 라미부딘을 투약한 만성 B형 간염 환자로 viral breakthrough가 발생한 74명을 대상으로 하였다(남/여 54/20, 평균연령 42세). Viral breakthrough 후 혈청 ALT치, 총 빌리루빈치, HBV DNA 역가, HBeAg, anti-HBe를 정기적으로 검사하면서 임상경과를 관찰하였다. Viral breakthrough 후 라미부딘의 투약기간은 평균 13개 월(1-41개월)이었다. 결과: Viral breakthrough 발생후 혈청 ALT치가 정상으로 유지되었던 환자는 8예(11%)에 불과했고 나머지 66예(89%)에서는 ALT치가 증가하였으며, 이중 30예(41%)에서 급성 악화(ALT 정상 상한치의 5배 이상 상승)를 보였다. 급성악화는 viral breakthrough 후 3개월 내에 19예 (63%)에서 발생하여 3개월 내에 발생한 예가 많았으나 12개월 이상 지나서 나타나는 예도 약 20%에서 있었다. 비대상성 악화는 6예에서 관찰되었다. Viral breakthrough 후 급성악화가 일어난 예와 없었던 예의 비교에서 급성악화를 예측할 수 있는 인자는 발견할 수 없었다. Viral breakthrough 후 발견할 수 없었다. Viral breakthrough 후 HBeAg이 음전된 예는 8예(11%)였으나 그 임상경과는 양호하지 않았다. 결론: 만성 B형 간염 환자 에서 라미부딘 투여 중 발생한 viral breakthrough 예 중 상당수에서 급성악화가 발생하였으며, HBeAg 이 소실되더라도 그 임상경과는 양호하지만은 않았다. Viral breakthrough 발생 후 주의 깊은 임상경과 의 관찰이 요구되며, 앞으로 viral breakthrough 후 급성악화 예에 대한 대규모 연구와 적절한 치료방향의 제시가 이루어져야 할 것으로 생각된다. Background/Aims: Long-term lamivudine therapy can induce the emergence of lamivudine resistant hepatitis B virus (HBV) mutants. Clinically emergence of the mutant is expressed by the reappearance of disappeared HBV DNA in serum. Continued lamivudine treatment has been usually recommended in cases of viral breakthrough. However, the clinical outcome in patients with viral breakthrough is not clear. The aim of this study was to investigate the clinical course of chronic hepatitis B patients after viral breakthrough during lamivudine therapy. Methods: A total of 74 patients with chronic hepatitis B who showed viral breakthrough after at least 6 months of lamivudine treatment were included in this study. They had positive HBeAg and HBV DNA before treatment. The median follow-up duration after breakthrough was 13 months. Results: After viral breakthrough, only 8 patients (11%) maintained normal ALT levels and 66 patients (89%) showed elevation of ALT. 30 patients (41%) showed acute exacerbation of hepatitis (ALT increase over five-times upper normal limit). These acute exacerbations occurred within three months after breakthrough in 19 patients (63%). In the cases of acute exacerbation, 6 patients showed decompensated progression such as elevation of serum total bilirubin. One of them died of hepatic failure. A predictive factor for acute exacerbation was not found. HBeAg seroconversion occurred in 8 patients after viral breakthrough but their clinical course was highly variable. Conclusions: Chronic hepatitis B patients who had viral breakthrough during lamivudine therapy should be followed carefully and regularly in mind of potential clinical deterioration. New strategies are needed to manage the cases of acute exacerbation after viral breakthrough.(Korean J Hepatol 2002;8:389-396)

      • Multiple occurrence of recurrent nodular fasciitis after surgical extirpation: masquarding as in-transit metastasis of sarcomatous presentation

        ( Kyung-nam Bae ),( Kihyuk Shin ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Gun-wook Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Hoon-soo Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

        Nodular fasciitis (NF) is a rare benign fibrous tumor related with a proliferative reactive process arising mostly from the muscular fascia or deep subcutaneous region. It distinctively appeared as solitary nodule in young-aged patient with rapid growth, which gives its other name as pseudosarcomatous fibromatosis. A 16-year old boy visited our clinic for the palpable mass on the left shoulder. The initial lesion had already been partially removed by the skin biopsy at local clinic. The biopsy specimen showed only fragments of fibrous mass consisting of collagenous stroma with spindle-shaped cells, but no atypia or mitotic figure. Surgical excision was performed, of which the surgical specimen showed invasion of spindle shaped cells involving subcutaneous layer interlacing with conspicious collagenous fiborus stroma without malignant features. After 3 months, two nodules reappeared near the operation sites and the following biopsy results showed the same as before. We decided to observe the remaining lesions and there had been no significant changes for 5 months. Multiple lesional occurrence is as quite uncommon feature of NF as the recurrence after surgical treatment. Herein, we report a rare case of multiple recurrence of NF after surgical extirpation, which presented with in-transit metastasis of sarcoma-like feature.

      • Erosive adenomatosis of the nipple presenting early improvement after short-term cryotherapy

        ( Kyung-nam Bae ),( Kihyuk Shin ),( Woo-il Kim ),( Min-young ),( Yang Won-ku Lee ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Gun-wook Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

        Erosive adenomatosis of the nipple (EAN) is a rare benign neoplasm characterized by the erosion of the nipple forming crust with serous or bloody discharge. Although there is no pronounced link between its nature course with the malignant transformation, the erosive deformity is directly related to the recurrent functional discomfort and cosmetic problem, resulting in deterioration of the quality of life. A 22-year old woman visited the breast clinic for her persistent deformity of the left nipple. She underwent a core-needle biopsy of a breast mass, which was incidentally found during a breast examination. However, no additional abnormalities were found except for fibrocystic change, and then visited to our clinic for evaluation of the skin lesion. The physical examination revealed serous and bloody erosion on top of the nipple with loss of half of its normal structure. The skin biopsy showed hyperplasia of the tubular structure composed of layers of cuboidal cells, but no atypia or pleomorphism. Then she received four times of cryosurgery every six-weeks, and after 6 months the nipple almost completely healed only remaining a tiny slit-like hole. Although the first choice of treatment for EAN is local excision, it is not quite feasible approach in young-aged female patients given the unsatifactory cosmetical outcomes and the anxiety for invasive procedure. Cryotherapy could be one of the acceptable option for the treatment of EAN.

      • 남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

        조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

      • KCI등재후보

        간암 환자에 합병된 Citrobacter braakii 패혈증 1례 보고

        이해미,배성하,이수남,이정우,신아영,류시영,이수연,윤문희,한선영,한남익,이영석,유진홍 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

        Citrobacter species is a gram-negative bacilli that can cause opportunistic infections in immunocompromised hosts. Citrobacter braakii refers to the genomospecies 6 of the Citrobacter freundii complex. There are no detailed studies on infections caused by this newly identified specific genetic species in Korea. We herein report a case of a patient with hepatocellular carcinoma who, after undergoing transcatheter arterial chemoembolization, developed biloma which later progressed to C.braakii sepsis and did not respond to treatment. To our knowledge, this is the first reported case in Korea on C. braakii infection resulting in septic shock in a patient with malignancy in Korea.

      • 韓國人의 初潮年齡에 關한 硏究 : 地域, 季節, 織業을 中心으로 Conducted toward the site, season, job

        南泰昊,趙榮濟,具光洙 釜山大學校 附設 體育科學硏究所 1988 體育科學硏究所 論文集 Vol.4 No.-

        This research aims at surveying the MIA and the menarche ages by using a follow-up survey of the Korean students height of the two schools in which the job of their parents and their living areas are somewhat different, some result can be withdrawn from this research. 1. The annual increase marks the height point at the age of ten and eleven, the average age of the object menarche marks 12.78 and the average height of them is marked by 151.5㎝. 2. In the relation between the menarche and the season, the objects usually have the menarche in the percentage of 36.82 in summer and in the percentage of 20.72 in August. 3. While the age of the menarche has be in being stationary in Norway and Sweden, that has been decreased 1960 to 1987 in Korea. 4. The ages of the menarche and the 3rd class industry has been lowered than that in the 1st and 2nd class industry.

      • W-CDMA 상향링크에서의 2-D RAKE 수신기 시뮬레이터 제작

        남원모,황태욱,김영수 경희-다반 ASIC 설계교육센터 2003 경희-다반 ASIC센터 논문집 Vol.4 No.-

        본 논문에서는 W-CDMA 상향링크 기지국에서 빔 형성 기술을 적용한 2-D RAKE 수신기 시뮬레이터를 제작하고 그 성능을 배열 안테나 수, RAKE 가지 수 및 총 사용자 수에 따라 1-D RAKE 수신기와 비교 분석하였다. 본 논문에서는 도심환경에서 수신되는 신호의 방향성분과 다중접속간섭신호를 실제에 가깝게 모델링 하기 위해 기존의 모든 사용자의 위치를 고정시키는 방법 대신 셀 내의 다수 사용자는 임의의 위치에 존재함을 가정하여 시뮬레이터를 제작하였다. 기본적인 채널 모델은 Rappaport에 의해 고안된 GBSBEM(Geometry Based Single Bounce Elliptical Model)을 응용하였으며, 레일리 페이딩 채널을 가정하였다. 2-D RAKE 수신기의 배열 안테나 수가 증가함에 따라 빔 패턴의 주엽의 범위가 좁아지고. 따라서 다중접속간섭신호를 효과적으로 제거함으로써 비트오율 성능이 획기적으로 개선되는 결과를 얻을 수 있었다

      • 당뇨병환자에서 호흡이 심박수에 미치는 영향

        남수현,오용구,박경욱,윤영길 慶北大學校 醫科大學 1981 慶北醫大誌 Vol.22 No.1

        당뇨병환자에서 자율신경 기능장애를 알아내기 위한 검사로서 심호기 심흡기율이 건강인에 비해 떨어져 있음을 심전도를 이용하여 검사하므로서 환자 침대에서 간단하게 그리고 정확하게 검사할 수 있었다. 당뇨병환자는 안정시 정상인에 비해 빈맥이 있으며, 심박수의 감소 또한 유의하게 적었다. 특히 건반사가 이상이 있는 당뇨병환자에서 건반사가 정상인 환자에 비해 심박수의 변화가 유의하게 적었으며 건반사가 이상인 환자에서 심흡기 심호기율이 1.10 이하는 56명중 49명으로 88%나 되었다. Retinopathy가 있는 환자에서 역시 심박수의 변화는 유의하게 적었고 심흡기 심호기 율이 1.10 이하인 예가 47명중 38명으로 78%나 되었다. 또한 단백뇨가 있는 환자에서도 심박수의 변화는 그 정도는 낮았으나 유의하게 적었다. 당뇨병의 병력기간이 길수록 심흡기 심호기율은 더 작아지는 경향은 확실하며 저자의 예에서는 병력기간이 1년이상 5년이하까지는 1.11±0.21 이였고, 5년이 넘어서서 10년 이하에서 1.07±0.03으로 1.10을 하회(下廻)하였다. 이와 같은 성적으로 미루어 보아 심호흡시 흡기 호기의 율을 계산함으로써 외과수술환자의 급성심폐부전에 의한 높은 사망율을 줄이는 데는 많은 도움이 될 것이다. To find a simple and accurate test of autonomic nervous dysfunction in diabetes mellitus, we performed maximal deep breathing procedures while undergoing electrocardiographic recording at bed side. Normal indivisuals at rest show variation in heart rate induced by respiration. During maximal deep breathing these changes are accelltuated and electrocardiographic recording will show the increase in heart rate during inspiration and the decrease during expiration. This variation is reduced or abscent in diabetics with autonomic neuropathy. Forty eight of the 56 with sensory neuropathy(88%) had an DE/Dl ratio below of 1.10. Diabetics with retinopathy also had significantly smallest variation and thirthy eight of the 47 with retinopathy(78%) had an DE/DI ratio below of 1.10. Also diabetics with proteinuria had significantly smaller variation. Relation between duration of diabetics and DE/DI ratio was inverse proportion accurately. For example in diabeticc of duration which above 1 year and below 5 years DE/DI ratio was 1.11±0.21 and in diabtiecs with below 10 years duration was 1.07±0.03. Our study cleary shows that diabetics with sensory neuropathy have a high prevalence of autonomic dysfunction, with may be important clinically. Since sudden cardiorespiratory deaths are common in diabetics with autonomic neuropathy during and after sugery, the determination of the DE/DI ratio might be a suitable preoperative test for those diabetics at risk. Patients with an abnormal ratio should probably be closely monitered in an intensive care unit after operation.

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