항장요법에 의한 白手?의 즉각형 과민반응 억제효과

문구,문석재,원진희,김태균,배남규,이종덕,임미양 한의병리학회 2001 동의생리병리학회지 Vol.15 No.5

각종(各種) 소화기(消化器) 증장(症狀)에 대(對)한 HPS-A의 임상(臨床) 치험(治驗)

문구,김세길 대한한방신경정신과학회 1992 동의신경정신과학회지 Vol.3 No.1

消化性潰瘍의 治法 및 運治方 活用에 對한 考察

文九,林圭庠,崔賢 圓光大學校 漢醫科大學 1989 圓光漢醫大論文集 Vol.- No.6

After finding out cure-all method by analyzing and synthesizing of Peon-Zheng-Shi-Chi(辨證施治) and clinical character of peptic ulcer, forming a cure-all prescription, attempting to conform the modificatory method of Kun(monarch). Shin(minister). Zhoa(assistant). Sha(guide) of forming drugs by Peon-Zheng(辨證) and modificatory drugs with Peon-Zheng-Shi-Chi(辨證施治) of Oriental medicine and pharmacologic effect of Western medicine, the author obtained conclusion as below. 1. The cure-all method based on the method of Peon-Zheng-Shi-Chi(辨證施治) are So-Kan-Hai-Wul (疏肝解鬱), Hoa-Wei (和胃), Hoal-Heol-Sang-ki (活血生肌), Hai-Keong-Zhin-Tong (解痙鎭痛), Jhei-San(制酸)(antacid). 2. The forming drugs of cure-all prescripiton are Radix paeoniae, Radix Glycyrrhizae, Rhizoma Cyperi, Radix Aucklandiae, Radix Linderae, Rhizoma Atracyodis, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Os Sepiae, Rhizoma Corydalis, Resina Myrrhae, Radix Astragali, Radix Adenophorae, Ramulus Cinnamomi. 3. The main durgs of each Peon-Zheng(辨證) are Rhizoma Cyperi, Radix Paeoniae Alba, Pericarpium Citri Reticulatae, Radix Aucklandiae, Radix Linderae in the symptoms of Ki-Chei(氣滯) Caused by Kan-Ki-Hoing-Yeog(肝氣橫逆) ; Radix Astrageli, Ramulus Cinnamomi, Radix Paeoniae Alba in the symptoms of Ki-Chei(氣滯) of Mog-Pul-So-To (木不疏土) caused by Kan-Ki-Her (肝氣虛) ; Radix Astragali, Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Atractylodis Macrocephalae in the symptoms of Her-Han(虛寒);Radix Adenophorae, Radix Paeoniae Alba in the symptoms of Wei-Yeum-Her(胃陰虛) and Wul-Yeol(鬱熱) ; Rhizoma Cyperi, Rhizoma cotydalis, Resina Myrrhae in the symptoms of Yer-Heol(瘀血) ; Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis in the symptoms od Tam-Kuel(痰厥). On the other hand, classifying and using the modification and utility method by the character of drug in order to coinside with Peon-Zheng (辨證) and pharmacologic effect, and finding out the therapeutic methods and prescriptions to protect the sideaction, it is considered that the better therapeutic effect will gain.

항장요법에 의한 白毛藤의 즉각형 과민반응 억제효과

문구,문석재,원진희,김태균,배남규,이종덕,임미양 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

The Solanum Iyratum Thunb. (Solanaceae) has been used against allergic disease for generations, and it still occupies an important place in traditional oriental medicine. In this study, the author investigated the effect of an aqueous extract of Solanum Iyratum on immediate-type hypersensitivity by anal administration. Anal administration of Solanum Iyratum showed a marked inhibition rate in systemic hypersensitivity with a dose of 0.1, 1 g/kg 1 hr before intraperitoneal injection of compound 48/80. Anal administration of Solanum Iyratum significantly reduced plasma histamine contents induced by compound 48/80. Anal administration of Solarium Iyratum (0.1 g/kg) also inhibited to 61.2%(P〈0.01) local allergic reaction activated by anti-dinitrophenyl (DNP) lgE significantly. In addition, Solanum Iyratum dose-dependency inhibited the histamine release from the peritoneal mast cells by compound 48/80 or anti-DNP IgE, When Solanum Iyratum was added, the level of cAMP in peritoneal mast cells transiently and significantly increased compared with that of basal cells. These results provide evidence that anal therapy of Solanum Iyratum may be beneficial in the treatment of systemic and local immediate-type hypersensitivity by inhibition of histamine release from mast cells in vivo and in vitro.

적취(積聚) 처방(處方)에 대(對)한 문헌적(文獻的) 고찰(考察)

문구,조성각,Mun, Gu,Jo, Seong-Gak 대한암한의학회 1996 大韓癌韓醫學會誌 Vol.2 No.1

Cancer is one of the most important cause of death. So recently, investigation of cancer progress prosperously all over the world. Cancer in the present medicine correspond to You-Am, Sin-Am, Young-Soon, Sel-Gyun, Sil-Young, Young-Lyoo, Seg-Je, Seg-Young, Seg-Ha, Jerk-Chui(積聚), Jing-Ha, Oel-Gyek, Ban-Oui, Bi-Gi, Bok-Lyang, Jang-Dan, Hyen-Bek in the oriental medicine. Among these, generally Jerk-Chui(積聚) is expressed to cancer. So to develop of new drugs of cancer in the present medicine, bibliographic investigation of mass-prescriptions was studied in the oriental medicine-books. According to the bibliographic study of Jerk-Chui-prescriptions, the results run as follows. 1. According to the analyses of three hundred sixty eight Jerk-Chui-prescriptions in the twenty-seven kinds of literature, the frequency number of the used drugs were Pericarpium Citri Nobilis Viride 140 times, Pericarpium Citri Reticulatae 135 times, Rhizoma Scirpi 124 times, Radix Aucklandie 115 times, Rhizoma Zedoariae 114 times, Cortex Magnoliae Officinalis 111 times, Radix Glycyrrhizae 106 times, Rhizoma Zingiberis 100 times, Rhizoma Coptidis 94 times, Radix Ginseng 93 times, Poria 86 times, Rhizoma Pinelliae 85 times, Semen Arecae 83 times, Rhizoma Cyperi 82 times, Radix Angelicae Sinensis 80 times, Rhizoma Atractylodis 74 times, Massa Fermentata Medisinalis 67 times, Radix Et Rhizoma Rhei 66 times, Fructus Aurantii 62 times, Fructus Hordei Genninatus 55 times, Conex Cinnamomi 54 times, Fructus Evodiae 51 times, Fructus Aurantii Immaturus 49 times, Fructus Crataegi 49 times, Rhizoma Cnidii 46 times, Radix Platycodi 44 times, Semen Tiglii 44 times, Radix Aconiti 43 times, Fructus Amoni 38 times, Semen Raphani 37 times, Radix Aconiti Praeparata 36 times, Radix Scutellariae 35 times, Pericarpium Zanthoxyli 35 times, Rhizoma Corydalis 33 times, Rhizoma Acori Graminei 31 times, Carapax Amydae 31 times, Fructus Foeniculi 31 times, Semen Persicae 30 times, Radix Bupleuri 30 times. 2. The frequency number of the most imponant used drugs in the Jerk-Chui-prescriptions were Rhizoma Coplidis 41 times, Rhizoma Scirpi 35 times, Radix Et Rhizoma Rhei 31 times, Pericarpium Citri Reticuiatae 30 times, Rhizoma Zedoariae 27 times, Rhizoma Cyperi 22 times, Cortex Magnoliae Officinalis 22 times, Rhizoma Atraclylodis 22 times, Pericarpium Citri Nobilis Viride 21 times, Rhizoma Pinelliae 20 times, Semen Arecae 20 times, Fructus Crataegi 18 times, Rhizoma Zingiberis 17 times, Carapax Amydae 16 times, Semen Pharbitidis 13 times, Poria 12 times, Radix Angelicae Sinensis 10 times, Semen Persicae 10 times, Fructus Evodiae 10 times, Radix Aeoniti 10 times, Radix Glycyrrhizae 9 times, Massa Fennenlata Medisinalis 9 times, Fructus Aurantii 9 times, Fructus Hordei Genninatus 8 times, Radix Aueklandie 8 times, Rhizoma Atractylodis 8 times, Radix Bupleuri 8 times, Radix Ginseng 7 times, Semen Raphani 7 times, Radix Astragali 7 times, Cortex Cinnamomi 6 times, Fructus Aurantii Immaturus 6 times, Rhizoma Cnidii 6 times, Radix Aconiti Praeparata 5 times, Fructus Foeniculi 5 times, Lacca Sinica Exsiccata 5 times, Radix Aconiti 5 times, Rhizoma Zingiberis 5 times. 3. The clinical-botanic classifications of the used drugs in the Jerk-Chui-prescriptions were regulating the flow of Qi drugs, warm-heating drugs, promoting blood circulation drugs, killing mass drugs, resolving drugs, purgative drugs, Qi and blood tonics drugs, heat clearing drugs, removing dampness by promoting diures is drugs, phlegm eliminating drugs, allaying pain drugs. 4. According to the nature and taste in the drugs, warm and heating recipes were used most, heatclearing recipes were used a few times assistantly. 5. The Jerk-Chui-prescription used frequently was Bun-Don-Tang, which was used 13 times ; Bok-Oyang-Hoan 12 times, Bi-Gi-Hoan(肥氣丸) 12 times, Sik-Boon-Hoan 12 times, A-Uie-Hoan 12 times, Bi-Gi-Hoan 12 times, Dai-Cil-Gi-Tang 8 times, San-Cuie-Tang 8 times, Guye-Gyen-Tang 6 times, On-Baig-Won 5 times, So

각종(各種) 소화기(消化器) 증상(症狀)에 대(對)한 HPS-A의 임상(臨床) 치험(治驗)

문구,김세길,Mun Gu,Kim Se-Gil 대한한방신경정신과학회 1992 동의신경정신과학회지 Vol.3 No.1

The effectiveness, the safety and the usefulness of HPS-A(An Jung San with Chyag Yag Kam Cho Tang), herbal digestive, was examined on 32 patients complained digestive symptoms. This medicine was administered 1 package per 1 time 3 times per 1 day, during 2 weeks. From the examination of the improvemnt and the safety mainly by subjective symptoms, the usefulness was gained. The results were as follows ; 1. In the improvement rate of susbjective symptoms, high rate symptoms was gastric distension, anorexia, heart burn, gastric discomport, dyspepsia, acrid eructation, indigestion, nausea. 2. The improvment over moderate effective was 85.7% after 1 week 96.4% after 2 weeks. The 4 cases breaked medicine during experimental period were all over moderate offectiveness. 3. There weren't any cases complaind particular problem about safety except for 1 case complained mild pushing up of heat. There weren't also any side effect of medicine on common blood count, blood chemistry and urinalysis. 4. In the dicision of usefulness, 19cases(59.4%) were usefulnesss, 12cases(37.5%) were moderate usefulness, 1 case was uselessness(3.1%). So the cases over moderate usefulness were 31 and rate was 96.9%. 5. The usefulness rates according to physical features were all over 95.5% in sturdiness, middle feature and infirmity. So the rates were no relations with the features. 6. The usefulness rates over moderate usefulness according to total seriousness were all over 90% in high, middle, and mild cases. So the rates were no relations with the seriousness. Totally HPS-A was a medicine that was highly effective, safe and useful to patients complained various digestive symptomes.

팔진탕합화적환(八珍湯合化積丸)과 Adriamycin의 병용처리시 나타나는 synergistic 항종양(抗腫瘍) 효과(效果)에 관(關)한 작용기전 연구(硏究)

문구,문석재,원진희,조정연,박상구,송봉길,박래길,이병구,Moon, Gu,Moon, Seok-Jae,Won, Jin-Hee,Cho, Jung-Yun,Park, Sang-Gu,Song, Bong-Gil,Park, Rae-Gil,Lee, Byung-Gu 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.3

Objective : This study was designed to evaluate the synergistic effect on cytotoxicity of combination with adriamycin and Palginhonhapwhajucwhan, a traditional prescription for cancer treatment in oriental medicine, in Chang, HL-60, Hep-3B and Alexander cells. Methods : We observed cell viability in Chang, HL-60, Hep-3B, and Alexander cells by crystal violet staining. Those cells were treated with various concentrations of adriamycin alone, Palginhonhapwhajucwhan alone and combination of two medications for 10 hr. On condition of $0.5{\mu}l/ml$ adriamycin alone, $15.6{\mu}l/ml$ Paljintanghapwhajucwhan alone and combination of two medications, at first, we observed colony forming of Chang and HL-60 cells. Second, we observed DNA fragmentation by agarose electrophoresis in Chang, HL-60, Hep-38 and Alexander cells. Third, we measured the catalytic activation of caspase-1, 2, 3, 6, 8, and 9 protease in Chang cells and caspase-3 protease in Chang, HL-60, Hep-3B and Alexander cells by using fluorogenic substrate. Finally, we isolated mRNA of Fas in Chang, HL-60, Hep-38 and Alexander cells and observed that Fas gene was amplified by RT-PCR Results : 1. The combination of adriamycin and Palginhonhapwhajucwhan synergistically augmented the cytotoxicity of Chang and HL-60 cells whereas did not in Hep-38 and Alexander cells. 2. Cotreatment of two drugs also markedly inhibited the colony forming ability both in Chang and HL-60 cells. 3. The cytotoxicity of these medicatons was revealed as apoptosis characterized by high molecular wight DNA fragmentaton. 4. The apoptotic cytotoxicity was mediated by activation of caspase-3 protease in Chang cells. 5. Synergistic increase in apoptotic cytotoxicity by combination of two medications was dependent on the expression of Fas in cancer cells. Conclusions : Combination of adriamycin and Palginhonhapwhajucwhan significantly augmented apoptotic cytotoxicity of Fas-positive cells such as Chang and HL-60 cells via acticaton of apoptosis signaling pathway.

積聚 處方에 對한 文獻的 考察

문구,조성각 대한한방종양학회 1996 대한한방종양학회지 Vol.2 No.1

Canser is one of the most important cause of death. So recently, investigation of cancer progress prosperously all over the world. Cancer in the present medicine correspond to You-Am, Sin-Am, Youg-Soon, Sel-Gyun, Sil-Young, Young-Lyoo, Seg-Je, Seg-Young, Seg-Ha, Jerk-Chuo(積聚), Jing-Ha, Oel-Gyek, Ban-Oui, Bi-Gi, Bok-Lyang, Jang-Dan, Hyen-Bek in the oriental medicine. Among thes, generally Jerk-Chui(積聚) is expressed to cancer. So to develop of new drugs of cancer in the present medicine, bibliographic investigation of mass-prescriptions was stodied in the oriental medicine-bodks. According to the bibliographic study of Jerk-Chui-prescriptions, the results rus as follows. 1. According to the analyses of three hundred sixty eight Jerk-Chui-prescriptions in the twenty-seven kinds of literature, the frequency number of the used drugs were Perivarpium Citri Nobilis Viride 140 times, Pericarpium Citri Reticulatae 135 times, Rhizoma Scirpi 124 times, Radix Aucklandie 115 times, Rhizoma Zedoariae 114 times, Cortex Magnoliae Officinalis lll times, Radix Glycyrrhizae 106 times, Rhizoma Zubguberis 100 times, Rhizoma Coptidis 94 times, Radix Ginseng 93 times, Poria 86 times, Rhizoma Pinelliae 85 times, Semen Arecae 83 times, Rhizoma Cyperi 82 times, Radix Angelicae Sinensis 80 times, Rhizonma Atractylodis 74 times, Massa Fermentata Medisinalis 67 times, Radix Et Rhizoma Rhei 66 times, Fructus Aurantii 62 times, Fructus Hordei Germinatus 55 times, Cortex Cinnamomi 54 times, Fructus Evodiae 51 times, Fructus Aurantii Immaturus 49 times, Fructus Crataegi 49 times, Rhizoma Cnidii 46 times, Radix Platycoi 44 times, Semen Tiglii 44 times, Radix Aconiti 43 times, Fructus Amoni 38 times, Semen Raphani 37 times, Radix Aconiti Praeparata 36 times, Radix Scutellariae 35 times, Pericarpium Zanthoxyli 35 times, Rhizoma Corydalis 33 times, Rhizoma Acori Graminei 31 times, Carapax Amydae 31 times, Fructus Foeniculi 31 times, Semen Persicae 30 times, Radix Bupleuri 30 times. 2. The frequency number of the most important used drugs in the Jerk-Chui-prescriptions were Rhizoma Coptidis 41 times, Rhizoma Scirpi 35 times, Radix Et Rhizoma Rhei 31 times, Pericarpium Citri Reticulatae 30 times. Rhizoma Zedoariae 37 times. Rhizoma Cyperi 22 times, Cortex Magnoliae Officinalis 22 times, Rhizoma Atractylodis 22 times, Pericarpium Citri Nobilis viride 21 times, Rhizoma Pinelliae 20 times, Semen Arecae 20 times, Fructus Crataegi 18 times, Rhizoma Zingiberis 17 times, Carapax Amydae 16 times, Semen Pharbitidis 13 times, Poria 12 times, Radix Angelicae Sinensis 10 times, Semen Persicae 10 times, Fructus Evodiae 10 times, Radix Aconiti 10 times, Radix Glycyrrhizae 9 times. Massa Fermentata Medisinalis 9 times, Fructus Aurantii 9 times, Fructus Hordei Germinatus 8 times, Radix Aucklandie 8 times, Rhizoma Atractylodis 8 times, Radix Bupleuri 8 times, Radix Ginseng 7 times, Semen Raphani 7 times, Radix Astragali 7 times, Cortex Cinnamomi 6 times, Frctus Aurantii Immaturus 6 times, Rhizoma Cnidii 6 times, Radix Aconiti Praeparate 5 times, Fructus Foeniculi 5 times, Lacca Sinica Exsiccata 5 times, Radix Aconiti 5 times, Rhizoma Zingiberis 5 times. 3. The clinical-botanic classifications of the used drugs in the drugs in the Jerk-Chui-prescriprions were regulating the flow of Qi drugs, warm-heating drugs, promoting blood circulation drugs, killing mass drugs, resolving drugs, purgative drugs, Qi and blood tonics drugs, heat clearing drugs, removing dampess by promoting diuresis drugs, phlegm eliminating drugs, allaying pain drugs. 4. According to the nature and taste in the drugs, warm and heating recipes were used most, heat-clearing recipes were used a few times assistantly. 5. The Jerk-Chui-prescription used frequently was Bun-Don-Tang, Which was used 13 times ; Bok-Oyang-Hoan 12 times, Bi-Gi-Hoan(肥氣丸) 12 times, Sik-Boon-Hoan 12 times, A-Uie-Hoan 12 times, Bi-Gi-Hoan(肥氣丸) 12 times, Dai-Cil-Gi-Tang 8 times, Sik-Boon-Hoan 12 times, A-Uie-Hoan 12 times, Bi-Gi-Hoan(肥氣丸) 12 times, Dai-Cil-Gi-Tang 8 times, San-Cuie-Tang 8 times, Guye-Gyen-Tang 6 times, On-Baig-Won 5 times, So-Jek-Jeng-Ouen-San 5 times, Jin=In-Hoa-Cel-Tang 5 times. Byel-Gab-San 5 times, Sng-Hong-Hoan 5 times, Ji-Sil-San 4 times, So-A-Oie-Hoan 4 times, Hyang-Rng-Hoan 4 times.

내시경을 이용한 전두부 지방종 제거술

문구현 충북대학교 의학연구소 2000 忠北醫大學術誌 Vol.10 No.2

연구목적: 지방종은 성형외과 영역에서 가장 흔히 접하게되는 연부조직 양성 종양이다. 작은 표재성 지방종은 증상이 없으나 안면부에 발생시에는 눈에 쉽게 띄기에 수술적 치료를 요하게 된다. 전통적인 안면부 지방종의 치료법은 피부절개를 통한 제거술이나 이는 술후 해당부위에 반흔이 필연적으로 남게된다. 최근 성형수술 분야에서 내시경의 이용이 점차 늘고 있어 최소한의 절개만으로 원하는 결과를 얻는 수술법들이 속속 소개되고 있으나 아직 안변부 지방종에 내시경을 이용한 보고가 없어 저자는 내시경을 이용한 지방종 적출술을 시도하여 이의 유용성을 확인하고자 하였다. 대상 및 방법: 최근 18개월간 전두부에 발생한 지방종 환자 4례에서 내시경을 이용한 적출 술을 시도하였다 종괴의 크기는 직경 2.0 -2.7cm 이었고 2개가 떨어져 동시에 발생했던 1례를 제외하고는 모두 단일 병변을 지니고 있었다. 직경 4mm의 내시경을 이용하여 전부두 골막하 박리와 종괴 적출을 시행하였다. 결과: 눈에 띄는 부위에 반흔을 남기지 않고 모든 례에서 성공적으로 종양을 제거할수 있었고 혈종, 감염, 신경손상과 같은 합병증은 발생하지 않았다. 조직학적 검사상 보두 지방종으로 확인되었고 모든 환자들은 미용적으로 매우 만족해 하였다. 추적 관찰에서도 지방종의 재발이나 전두부 윤곽 변형등의 이차적인 합병증은 발생하지 않았다. 결론: 본 수술법은 원위부 절개를 통해 보이는 곳에 반흔을 남기지 않으면서도 전부두에 발생한 지방종 제거에 효과적인 방법이라고 사료되며 안면 다른 부위에서도 선택적으로 이용할 수 있으리라 판단된다. Purpose : Lipomas are probably the most common benign soft tissue tumor presenting to the cutaneous surgeon. Small superficial lipomas are symptom free but facial location rendered patients to receive surgery because of cosmetic concerns. Traditional treatment of facial lipoma has been direct excision with incision placed over the tumor which resulted in linear scar on corresponding location. In recent plastic surgery fields, endoscopy-assisted procedures are widely applied for minimal Incision technique so the author tried endoscopic extirpation of facial lipomas to evaluate it's efficacy. Materials and Methods: Four patients having forehead lipomas are included in this study. Diameter of the lesions were ranged from 2.0 to 2.7 centimeter and all had single mass except one case with double lesions. 4mm diameter endoscpoe was used for subperiosteal dissection and lipoma removal. Results: All tumors are successfully removed without noticeable scars on forehead and other morbidity like hematoma, infection and nerve problem. Histologic confirmation of lipoma was done. Cosmetically patients were very satisfied with the results and during follow -up, late comlications like recurrence and contour irregularity didn't occurred. Conclusion : The author concluded this endoscopy assisted extirpation with remote incision results in cosmetically excellent results and should be primary option in facial lipoma treatment.

倫落女性에 對한 現況 및 性病에 關한 硏究

文九鉉 慶北大學校 1964 論文集 Vol.8 No.-

Five hundred and ten prostitutes living in Taegu, Kyung Joo, and Pou Hang areas were investigated for their present conditions and morbidities of the venereal diseases. Bacteriological studies of 28 strains of gonococci, 33 of coagulase positive and 75 of coagulase negative staphylococci isolated from the cervix were also made, and the following results were obtained. Ⅰ. Present conditions of prostitutes. 1. Ages of 66.6% of prostitutes were from 21 to 25 years. 2. Ages of menarche ranged from 16 to 19 years in most cases (80%). 3. First sexual intercourse was made under the ages of 20 years in 77.0%. 4. 89.0 per cent of prostitutes had not received an education higher than the level of primary school. 5. In 62.4% of prostitutes, it was found that they had no jobs in the past. 6. Important motives of the first sexual intercourse were love affaris (48.0%) and prostitution (22.0%). First intercourse of most of prostitutes (82.0%) was extra-marital. 7. Causes of fall into the misery were the difficulty in economic condition (57.1%0, seduction (27.6%) and abandonment (15.3%). 8. Prostitutes from urban areas showed a little higher percentage than those from rural areas. Ⅱ. Venereal diseases. 1. Lesions and/or pus discharges in the cervix were found in 51% of prostitutes and cervical erosions in 33.2%. 2. Gram negative diplococci in discharges were observed intracellularly or extracellualry in 31% of persons examined, and a high incidence of Gram negatice diplococci was noted among prostitutes for Koreans than in those for U.N. Forces. The appearance of leucocytes and Gram positive diplococci in discharges were almost the same in the both groups of prostitutes. 3. Thirtytwo strains of gonococci were isolated from specimens showing Gram negative diplococci upon staining, and three strains from those showing no Gram negative diplococci. 4. Thirtyfive strains out of 95 Gram negative diplococci showing positive oxidase reaction were identified as gonococci and the remaining as N. catarrhalis, N. sicca, N. flava or mimea group. 5. Gonococci were sensitive to penicillin, less sensitive to terramycin and erythromycin, moderately resistant to chloramphenicol, kanamycin and albamycin, and highly resistant to streptomycin and sulfadimethoxine. 6. One hundred and sixtytwo strains of staphylococci were/isolated from cervical discharges, and 33 strains of them were coagulase positive. 7. Among 33 strains of coagulase positive strains, 20 strains were identifed belonging to phage groupⅠ, one mixed group and 12 non-typable. Strains belonging to groupⅠ were identified as phage type 29 and one belonging mixed group as 29/6. 8. The sensitivity of staphylococci to various antibiotics showed no marked difference between coagulase positive and negative ones. Most of the strains were sensitive to antibiotics, and very few of them were resistant. 9. Serological test for syphilis was positive by VDRL test in 10.5% of prostitutes, while Syphilis recenta was not found. The incidence of positive VDRL test was higher among prostitutes in areas of poor sanitation and higher among those for Koreans. 10. Chancroid was found in 11 cases (1.9%) but Lymphogranuloma venereum and Granuloma inguinale were nor found.