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류주현 한국 지리·환경 교육학회 1999 한국지리환경교육학회지 Vol.7 No.1
The use of color for representing geographic data on maps raises many questions. This study addresses questions about which color ensures accurate map reading and which color scheme is suitable for a specific geographic data. Two internal and external experiments and a review of previous color research have been conducted to establish and evaluate criteria for selecting colors to be used to represent geographic data. As a result, color use has proved to be effective in increasing accuracy in map reading. Maps are a unique way of communication and they convey geographic and spatial data. Generally, hue-value color schemes are the most effective method to represent geographic data. Hue-value schemes obviously have the advantages of hue differences and value variation. But I think that common rule is not enough. This study focuses on establishing guidelines which will enable optimal use of colors in map making. Previous research has confirmed the importance of colors, but colors have never been dealt with as an independent factor in map making. I would like to provide these guidelines here: First, map makers should select appropriate color schemes according to the haracteristics of data. For instance, they should select a hue-based scheme for qualitative data and a value-based scheme for the quantitative data. Second, quantitative data can be divided into three groups. Therefor, different schemes should be applied according to the characteristics of quantitative data. Third, the type of map task or the correlation between geograhic data and space is also a major factor in selecting color schemes. For instance, hue-based scheme is the most suitable to provide individual regional geographic data. Value-based scheme is the most suitable to provide the general trend of map. And the color scheme is influenced by direct acquisition task or recall task Forth, the education level of map users should be considered in map making. Specially numbers of data classes. Research on color symbolization is important in that computer mapping software is now widely available. Guidelines should be provided to improve the design of customized color schemes. Appropriate use of color schemes can improve the effectiveness of maps, improved color schemes will help map makers, including geography teachers, to gain insights into data.
Chemo-resistant choriocarcinoma metastatic to colon cured by low-anterior resection
류주현,최철훈,김태중,이정원,김병기,배덕수 대한부인종양학회 2011 Journal of Gynecologic Oncology Vol.22 No.3
The role of surgery in the treatment of patients with metastatic choriocarcinoma has diminished. We present a case of chemo- resistant metastatic choriocarcinoma salvaged by surgery. A 48-year-old patient presented with uterine perforation and severe intractable hemorrhage, and histological examination revealed a choriocarcinoma. After 6 years of disease-free state, recurrence occurred in the rectosigmoid colon. Seven cycles of EMACO chemotherapy was administered, and the human chorionic gonadotropin level was normalized. Three months after the chemotherapy, the rectosigmoid colon metastasis progressed. Low anterior resection with lymphadenectomy up to the level of the inferior mesenteric artery was conducted. After the operation, the human chorionic gonadotropin level decreased to within the normal range. There has been no evidence of disease for 13 months since the operation. Local resection of metastases seems to play a significant role in curing the disease in a small subset of patients.
BiFe<sub>3</sub>첨가에 따른 저온소결 PSN-PZT세라믹스의 유전 및 압전 특성
류주현,정광현,정영호 한국전기전자재료학회 2004 전기전자재료학회논문지 Vol.17 No.5
In this study, (0.96 -x)(PSN-PZT)-xBF-0.04 PNW+0.3wt%MnO$_2$+0.6wt%CuO ceramics were fabricated with the variations of the amount of BiFeO$_3$substitution and sintering temperature for the development of modified ceramics which can be sintered in the low temperature($\leq$100$0^{\circ}C$ ), and their microstructural, dielectric and piezoelectric characteristics were investigated. As the amount of BiFeO$_3$ substitution was increased, the density, mechanical quality factor(Q$_{m}$) and electromechanical coupling factor(k$_{p}$) showed the maximum value at each of sintering temperature. At sintering temperature of 98$0^{\circ}C$ and BiFeO$_3$substitution of 2 mol%, the density, dielectric constant and electromechanical coupling factor(k$_{p}$) showed the maximum value of 7.84 g/㎤, 1415 and 0.49, respectively. And at sintering temperature of 95$0^{\circ}C$ and BiFeO$_3$substitution of 3mol%, mechanical quality factor showed the maximum value of 1062. 1062.
저온소결 PMN-PNN-PZT세라믹스의 소결온도에 따른 미세구조 및 강유전특성
류주현,이현석,이상호,Yoo, Ju-Hyun,Lee, Hyun-Seok,Lee, Sang-Ho 한국전기전자재료학회 2006 전기전자재료학회논문지 Vol.19 No.12
In this study, in order to develop the low temperature sintering multilayer piezoelectric actuator, PMN-PNN-PZT system ceramics were manufactured and their microstructure, ferroelectric and piezoelectric properties were investigated. By increasing sintering temperature, remanent polarization$(P_r)$ was increased due to the increase of sinterability and grain size. However, coercive $field(E_c)$ showed an opposite tendency to remanent polarization owing to the feasibility of domain wall motion. At the sintering temperature of $900^{\circ}C$, dielectric $constant({\varepsilon}_r)$, electromechanical coupling $factor(k_p)$, piezoelectric $constant(d_{33})$ and mechanical quality $factor(Q_m)$ showed the optimal value of 1095, 0.60, 363 and 1055, respectively, for multilayer piezoelectric actuator application.
3차 진동모드를 이용한 종속 연결된 고주파 필터 특성에 미치는 결합 캐패시턴스의 영향
류주현,오동언 한국전기전자재료학회 2003 전기전자재료학회논문지 Vol.16 No.10
In this paper, two filters with center frequency of 19.58MHz were cascaded and its bandwidth characteristics were investigated with the variations of coupling capacitance for intermediate frequency (IF) bandpass filter application. The cascaded filter showed the higher stop region, reduction of spurious response and increase of selectivity. With the increase of coupling capacitance, insertion loss was increased but spurious response reduced. The cascaded filter with coupling capacitance of 15pF showed insertion loss of 5.643dB, 3dB bandwidth of 55.089kHz and 20dB bandwidth of 83.608kHz, respectively.
A proteomic analysis of differentiating dopamine neurons derived from human embryonic stem cells
류주현,박병철,이도희 한국통합생물학회 2019 Animal cells and systems Vol.23 No.3
Human embryonic stem cells (hESC) are being exploited for potential use in cell transplantation due to their capacity for self-renewal and pluripotency. Dopamine (DA) neurons derived from hESC represent a promising source of cell replacement therapy for Parkinson’s disease (PD). While gene expression on the transcriptome level has been extensively studied, limited information is available for the proteome-level changes associated with DA neuron differentiation. Here we analyzed the proteome of differentiating DA neurons to search for the potential biomarkers to assess the efficiency of differentiation. Although the proteome profile of DA neurons did not exhibit significant changes, a number of cytoskeletal proteins including nuclear lamin, tropomyosin 1, and myosin light chain 1 were specifically up-regulated during differentiation. Expression analysis of the respective genes was also consistent with the proteome results. In addition, these differentially expressed proteins form protein interaction network with several PD-related proteins suggesting that they may play roles in PD pathogenesis as well as the maturation of DA neurons.