변화치 및 경고치 검색과 Q-flag limit를 이용한 혈구산정검사의 검사소요시간

구본경,유광현,임대진,조영국,김희진 대한임상검사과학회 2012 대한임상검사과학회지(KJCLS) Vol.44 No.2

Test turnaround time (TAT) is the lead time from reception to reporting. In the complete blood cell count (CBC), 4 units of the XE-2100 (Sysmex Corp., Japan) processed around 80% of quantity, 1 unit of the LH-780 (Beckman-Coulter Incorp., USA) processed around 10% and 1 unit of ADVIA-2120 (Siemens AG, Munich, Germany) processed around 10%. We analyzed the change in the TAT for the CBC for over 7 years, from January of 2005 to December of 2011. The delta check made alterations of delta to WBC, hemoglobin, hematocrit, platelet and metamyelocyte, however, did not made them to band neutrophil, eosinophil, basophil and monocyte. The panic value check made alterations of panic value to hemoglobin, hematocrit, platelet and monocyte. In the criteria of currently slide review, LH-780 and ADVI-2120 analyzers prepared suspect flags of “Blast, Imm NE2, Immature granulocyte, Imm NE1, Left shift, Variant lymphocyte, Atypical lymphocyte, Platelet clumps and NRBC”. The New slide review in the XE-2100 analyzer altered the preparations of a smear slide more than a “Platelet clumps flag(≥200 unit), a single flag excluding the “Platelet clumps flag (≥250 unit) and a multiple flag (≥200 unit)”. Also, below the 240 unit, medical technologists prepared manual slides selectively according to their evaluations. The automatic reporting rate was 33.4% without alterations, whereas it was 41.0% without alterations, and was thus improved by 7.6%. The slide review rate was 15.2% before using the Q-flag limit, whereas it was 12.1% for a reduce 3.1%. TAT was 45 minutes without the creation alterations of the delta and panic value checks, whereas it was 35 minutes after making alterations of the delta and panic value checks and thus was shortened by 10 minutes. We came to the conclusion that the establishment and operation of delta and panic value checks and slide review criteria suitable for laboratory environment can reduce unnecessary smear slides, re-checking, re-sampling, re-testing, telephone inquiries and concentrated workloads during specific times of the day. .

포스터(혈액) 19 : 골수 및 유세포검사 논문 조사: 1967-2012년(46년간) 대한임상검사학회지

구본경,김정해,심현설,이범세,이용탁,임대진,장석 대한임상병리사협회 2013 임상혈액검사학회 발표자료집 Vol.15 No.1

북한 이탈 여성에 대한 여성주의 목회상담적 이해: 생존의 모티브 하갈을 중심으로

구본경 한국여신학자협의회 2022 한국여성신학 Vol.- No.96

임상병리사국가시험 및 직무의 변천 비교를 중심으로 한 기초자료 제안: 한국, 일본, 대만을 중심으로

구본경,Myung Soo KIM,김윤식,이준호 대한임상검사과학회 2023 대한임상검사과학회지(KJCLS) Vol.55 No.2

This study examined the transition process of clinical laboratory technologists’ national examination and job definition in Korea and compared the differences in the national examination between Korea and neighboring countries, such as Japan and Taiwan. In Korea, the number of questions made for it was 200 (1965), 200 (1977), 300 (1982), 250 (1992), 330 (2006), and 280 (2015). The practice of clinical physiology is important for real-time monitoring, given the characteristics of physiological testing. On the other hand, there are conflicts between other occupations in the working area. Clinical molecular biology needs to be established as a new major subject considering the diagnostic importance of molecular biological tests and the speed of science and technology development. Clinical laboratory operations provide policy and guidance recommendations to technologist staff. The proposed clinical laboratory technologists’ national examination comprises major subjects: clinical biochemistry, clinical hematology, clinical transfusionology, clinical immunology, clinical microbiology, clinical molecular biology, clinical histology, clinical cytology, clinical physiology, and clinical laboratory operations. In addition, this study proposes the job definition of clinical laboratory technologists, revising various chemical or physiological testing to biomedical or physiological testing required for medical practice.

CEO 교체와 연임에 따른 기업 성과 비교 연구

구본경 한국재무학회 2008 한국재무학회 학술대회 Vol.2008 No.11

기업 지배 구조 개선 운동만으로 기업의 재무 구조 개선과 기업 가치 향상이 완전히 반영 되지 않고 있다는 문제점때문에 조직 환경내 인적 자원 활동에서 원인을 찾아보았다. 한국 사회에서 기업 문화를 중시한다는 것을 고려한다면 조직 환경속의 CEO 존재의 중요성을 들 수 있어 본 연구에서는 CEO 활동이 기업 성과에 미치는 영향을 살펴보았다. CEO의 안 정된 경영권 확보 유무가 기업의 장기 성과에 미치는 영향을 보기 위해 임기 기준으로 임기 도중 교체된 후 CEO의 기업 성과와 경영권을 확보한 이후 연임 기업 성과간 차이를 비교 하였다. 또 CEO 교체 시기가 일정치 않은데도 통상적으로 직전 년도말 또는 당해 재무 성 과로 기업 성과를 측정하는 것은 순수한 교체와 연임 성과를 반영할 수 없다는 문제점을 지 적하고, 정보 반영 손실의 최소화를 위해 교체와 연임 직전 분기 자료를 사용하여 미래 CEO의 장기 성과를 살펴보았다. 각 조직 환경과 조직 환경내 CEO 특성 변수들을 통제한 이후 교체와 연임 기업의 공시 전후 기업 가치의 성장성과 수익성을 비교하였다. 기업들은 교체에 대한 위험 부담으로 특별한 사유가 없는 한 연임을 선택하지만, 전문 경영자 집단에 서의 연임 효과를 제외한 대부분의 실증 분석 결과에서 교체가 연임에 비해 기업 성과의 비 교 우위를 가지는 것으로 나타났다. 교체와 연임 결정 요인은 과거 재무 성과보다는 CEO와 조직 환경 관련 요인이 크게 좌우하는 것으로 나타났다. CEO의 경영권 안정 확보가 기업 성과로 이어지지 않고 있어 소유 경영자 기업이 대부분인 한국 기업 사회에서 경영의 투명 성이 전제되지 않는 한 전문 경영자 체제 정착이 어렵다는 것을 알 수 있었다. 재벌 기업을 제외한 단일 체제의 비재벌 기업에서는 오너 중심의 경영으로 적시 교체가 효율적인 것으로 나타났다. 경영권의 안정권 확보라는 동일한 조건에서 교체와 연임 모두 수익성이 좋지 않 으나 교체보다는 위험 부담이 낮은 연임을 선택하는 것으로 나타났다. In this study I examine cause from human resource activity understanding that corporate governance improvement campaign doesn't clearly reflect financial structure improvement and firm value improvement. If we consider importance of corporation culture in Korea sociaty, we realize CEO existence in organization environment. In this study I examine impact affecting CEO managerial activity on firm value. After considering tenure cycle to see influence affecting on long-term performance, I study performance difference in CEO succession before and after CEO term-expiration. It is generally used annual data of just before year or the end of a year in past study in spite of happening CEO turnover timing irregularly. I use quaterly data to minimize information reflection loss about CEO's long-term performance. I compare firm value profitability with growth between CEO turnover and CEO term-expiration succession after controlling several organization environmental and CEO characteristic variables. I discover in having a high performance after CEO turnover better than term-expiration succession in various results. It appears that corporations prefer term-expiration succession to CEO turnover because of taking a risk. It can be seen not by past financial performance but by relating CEO managerial activity in organization environment. I judge that it is difficult in maintaining revitalization of professional CEO regime in Korea corporation sociaty as long as not having managerial transparency. It appears that owner management is more effective CEO turnover immediately in non-chaebol firm.

구연발표1 (혈액) : 구연5 ; XE-2100 자동혈구분석기와 STA-R 자동응고분석기에서의 간섭물질 평가

구본경,전영진,유광현,김희진 대한임상병리사협회 2011 임상혈액검사학회 발표자료집 Vol.13 No.1

자폐아 중재에 관한 국내 연구 분석:1997년~2006년 등재(후보)학술지 논문을 중심으로

구본경,신현기 한국특수아동학회 2007 특수아동교육연구 Vol.9 No.3

The purpose of this study was to synthesize Intervention studies for students with autism and present suggestions for future intervention studies. An extensive search process yielded a total of 92 intervention studied in journal articles published in major journals from 1997 to 2006 in Korea. Synthesis indicate as follows: first, the intervention studies for students with autism was increasing for the 10 years, the most of study subjects was 3 students and more than 50% that were preschool childhood. The most diagnosed autism by CARS, the mostly instructor was researchers, and the most used intervention setting was clinic. Second, the most study of intervention duration was 31-40 mins and the most intervention term was 1-2 months. The most research design was single-subject design and analysis method was th visual analysis on the graphs. Over 40% of studies were reported maintenance or follow-up and reliability, but few of that was reported generalization and social validity. Third, the most intervention strategies were other interventions and treatments such as art therapy, music therapy, physical activity, and related program. After skill-based interventions and treatments, interpersonal relationship interventions and treatments followed it. Target behaviors were social skill, communication, challenge behaviors were high similarly. Fourth, in preschool childhood used applied behavior analysis, in school childhood and in adolescence most used physical activity. For school childhood and adolescence intervened in challenge behaviors, for preschool childhood and adulthood intervened in communication. Based on the results, limitation of this study and future research issues were discussed. 본 연구에서는 1997년부터 2006년까지 국내의 등재 및 등재후보 학술지에 게재된 자폐아 대상의 중재연구물 92편을 분석하였다. 자폐를 가진 학생을 대상으로 한 중재연구의 분석을 위해 첫째, 일반적인 특성(연구대상, 진단도구, 중재자, 중재환경) 둘째, 설계상 특성(실험설계방법, 중재결과의 분석방법, 중재의 회기당 시간, 중재기간, 유지/추후검사, 일반화, 신뢰도, 사회적 타당도의 빈도) 셋째, 중재연구의 중재방법과 중재의 목표행동, 넷째, 생애발달별 중재방법과 목표행동의 빈도를 분석하였다. 분석결과, 최근 10년간 중재연구는 지속적으로 증가하였는데, 대상자는 학령전 아동, 진단도구는 CARS, 중재자는 연구자가 가장 많았고, 중재환경은 치료실이 가장 빈도가 높았다. 설계상 특성의 결과, 중재시간은 31-40분으로 기간은 1-2개월의 빈도가 가장 높았고 단일대상연구로 시각적 그래프를 제시한 연구가 가장 많았다. 유지/추후검사와 신뢰도는 40%이상, 일반화와 사회적 타당도는 소수 연구물에서만 보고하고 있었다. 중재방법은 기타치료 및 프로그램, 기술중심중재, 인간관계중심중재 순이었고, 목표행동은 사회성, 의사소통, 문제행동이 비슷하게 높은 빈도를 보였다. 생애발달별 분석결과, 학령전 아동에게는 응용행동분석이, 학령아동기와 청소년기에는 신체활동이 가장 많이 사용되었으며, 학령전 아동기와 성인기에는 의사소통이 학령기 아동기와 청소년기에는 문제행동을 가장 많이 목표행동으로 하였다. 이 결과를 토대로 연구의 제한점과 앞으로의 연구과제를 제시하였다.

헤파린민감도평가를 위한 두 가지 방법의 비교; 체외에서 헤파린 혼합 혈장을 사용한 aPTT 검사와 헤파린 치료중인 환자 혈장을 사용한 anti-Xa 검사

구본경,권의훈,유광현,윤재원,김희진 대한임상검사과학회 2011 대한임상검사과학회지(KJCLS) Vol.43 No.4

The monitoring of heparin therapy is using almost aPTT assay. This study is compare to estimating aPTT therapeutic range using in vitro heparin-spiked sample and aPTT therapeutic range using in vivo heparin-treated sample. Normal pooled plasma was collected from 20 healthy representative individuals. 11 concentration of heparinized plasmas from 0 U/mL to 1.0 U/mL at intervals of 0.1 U/mL made by addition of heparin to normal pooled plasma were measured aPTT. The aPTT therapeutic range was performed through correlation analysis between heparin level 0.2 to 0.4 U/mL and aPTT. 30 plasmas from patients on heparin therapy were measured aPTT and anti-Xa activity. The aPTT therapeutic range was performed through correlation analysis between anti-Xa activity 0.3 to 0.7 U/mL and aPTT. The aPTT therapeutic range corresponded by heparin level-vs-aPTT value regression analysis was 60.7 to 102.4 seconds. The aPTT therapeutic range corresponded by anti-Xa activity-vs-aPTT value regression analysis was 85.3 to 147.5 seconds. The validation of heparin sensitivity using in-vitro heparin sample was not considered. The establishing aPTT therapeutic range is recommended anti-Xa activity using in-vivo sample. .

한국, 일본, 미국 임상병리사 전문자격

구본경 대한임상검사과학회 2019 대한임상검사과학회지(KJCLS) Vol.51 No.1

The names of medical technologist in Korea, Japan, and the United State of America vary depending on the medical system, educational system, and work areas. Conventionally, jobs equal or similar to medical technologist (commonly known as clinical laboratory technologist, medical laboratory technologist, clinical laboratory scientist, and medical laboratory scientist), histotechnologist, cytotechnologist, and genetic technologist. Jobs, such as extracorporeal technologist, medical electrophysiology technologist, and medical sonographer, allow other allied health professionals including medical technologists, to obtain their qualification. The work areas of medical technologists are classified into clinical pathologic technology, pathologic technology, clinical genetics technology, nuclear medicine in vitro technology, and clinical physiologic technology. New titles of Korean specialized medical technologists refer to certification systems, such as CLMJ, CMAJ, ASCP, IAC, ABRET, and ARMDS. Currently, there are eight types of specialized medical technologists under the cooperation of specialized academic societies. They are hematology, transfusionology, chemistry, immunology, microbiology, histology, cytology, nuclear medicine. It can be further divided into 20 categories according to the work areas such as mass spectrometry, infection control, Pathologists’ Assistant, flow cytometry, HLA, cytogenetics, molecular genetics, cardiopulmonary physiology, neurophysiology (EEG/EMG/PSG/etc.), cardiac sonography, neurosonography (TCD/carotid), and medical device quality manager. 우리나라, 일본, 미국의 임상병리사 명칭은 의료체계, 교육제도, 업무영역에 따라 차이가 있다. 전통적으로 medical technologist (별칭 clinical laboratory technologist, medical laboratory technologist, clinical laboratory scientist, medical laboratory scientist)와 동등하거나 유사한 직종은histotechnologist, cytotechnologist, genetic technologist 이다. Extracorporeal technologist, medical electrophysiology technologist, medical sonographer는 medical technologist를 포함한 다른 보건의료인도 자격을 취득할 수 있는 직종이다. 임상병리사의 업무영역은 임상병리기술학, 병리기술학, 임상유전기술학, 핵의학기술학, 임상생리기술학으로분류하였다. 새로운 전문임상병리사 종별은 CLMJ, CMAJ, ASCP, IAC, ABRET, ARMDS 등의 자격인정제도를 참고하였다. 현재 전문임상병리사 종별은 전문과목학회의 협조 하에 기존의 8종으로 혈액학, 수혈학, 화학, 면역학, 미생물학, 조직학, 세포학, 핵의학분야가 있으며 앞으로 미세질량분석, 감염관리, Pathologists’ Assistant, 유세포분석, HLA, 세포유전학, 분자유전학, 심폐생리학, 신경생리학(뇌파/근전도/수면다원 등), 심장초음파학, 신경초음파학(뇌혈류/경동맥), 기기품질관리사등 업무영역별로 20종으로 세분화할 수 있다.

아동이 지각한 부모의 언어 통제 유형과 아동의 내외 통제 소재와의 관계

구본경,김수정,김영지,김정은,김지현,박상미,양희정,유민아,윤지연 연세대학교 생활과학대학 1998 생활과학 Vol.- No.31