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      • KCI등재

        Effect of Halloysite Nanotubes (HNTs) on Mechanical Properties of EPDM/NBR Blend-Nanocomposites

        Raj Kishor Das,K. Ragupathy,T. Senthil Kumar,S. Vishvanathperumal 한국고분자학회 2023 폴리머 Vol.47 No.2

        The nanocomposite of ethylene-propylene-diene monomer (EPDM), acrylonitrile-butadiene rubber (NBR), and halloysite nanotubes (HNTs) was produced. On a two-roll mill, the 0–25 parts per hundred rubber (phr) of HNTs with 70/30 EPDM/NBR was mixed. The effect of HNT on the cure characteristics (scorch (tS2) and optimum cure time (t90), cure rate index, maximum torque, minimum torque and torque difference) and mechanical properties of the composites were studied and discussed. Scanning electron microscopy (SEM) was used to examine the surface morphology of tensile-fractured EPDM/NBR rubber-HNTs. Tensile strength, 100% modulus, elongation at break, tear strength, hardness, abrasion resistance, and compression set were increased whereas rebound resilience, tS2, and t90 were decreased with increasing in the concentration of HNTs in it.

      • SCISCIESCOPUSKCI등재

        Effect of Pulsed Current GTA Welding Parameters on the Fusion Zone Microstructure of AA 6061 Aluminium Alloy

        ( T. Senthil Kumar ),( V. Balasubramanian ),( S. Babu ),( M. Y. Sanavullah ) 대한금속재료학회 ( 구 대한금속학회 ) 2007 METALS AND MATERIALS International Vol.13 No.4

        AA6061 aluminium alloy (Al-Mg-Si alloy) has gathered wide acceptance in the fabrication of food processing equipment, chemical containers, passenger cars, road tankers, and railway transport systems. The preferred process for welding these aluminium alloys is frequently Gas Tungsten Arc (GTA) welding due to its comparatively easy applicability and lower cost. In the case of single pass GTA welding of thinner sections of this alloy, the pulsed current has been found beneficial due to its advantages over the conventional continuous current processes. The use of pulsed current parameters has been found to improve the mechanical properties of the welds compared to those of continuous current welds of this alloy due to grain refinement occurring in the fusion zone. In this investigation, an attempt has been made to develop a mathematical model to predict the fusion zone grain diameter incorporating pulsed current welding parameters. Statistical tools such as design of experiments, analysis of variance, and regression analysis are used to develop the mathematical model. The developed model can be effectively used to predict the fusion grain diameter at a 95 % confidence level for the given pulsed current parameters. The effect of pulsed current GTA welding parameters on the fusion zone grain diameter of AA 6061 aluminium alloy welds is reported in this paper.

      • Antitumor effect of Careya arborea against Ehrlich ascites carcinoma with reference to lipid peroxidation and enzymatic and non enzymatic antioxidant system in Swiss albino mice

        Kumar, R Sambath,Sivakumar, T,Senthil, V,Murthy, N Venkateswara,Balasubramaniam, V,Sabi, R Kanaga,Sundram, R. Shanmuga,Perumal, P,Mazumder, U K,Gupta, M Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.8 No.2

        The methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family- Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich's Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice.

      • KCI등재후보

        Antitumor effect of Careya arborea against Ehrlich ascites carcinoma with reference to lipid peroxidation and enzymatic and non enzymatic antioxidant system in Swiss albino mice

        R Sambath Kumar,T Sivakumar,V Senthil,N Venkateswara Murthy,V Balasubramaniam,R Kanaga Sabi,R. Shanmuga Sundram,P Perumal,U K Mazumder,M Gupta 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.2

        The methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family- Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich’s Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice. The methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family- Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich’s Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice.

      • KCI등재

        Improved Thermal Stability of Green InGaN/GaN Multiple-Quantum-Well Light-Emitting Diodes with an AlGaN/GaN Short-Superlattice-Inserted Structure

        Y. S. Lee,M. Senthil Kumar,T. V. Cuong,J. Y. Park,J. H. Ryu,S. J. Chung,E.-K. Suh,C.-H. Hong 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.1

        We report an amelioration of the electrical, thermal and optical performances of green InGaN/GaN multiple-quantum-well light-emitting diodes (LEDs) with AlGaN/GaN short- superlattice (SSL)-inserted structure grown using metal-organic chemical vapor deposition. Ac- cording to an atomic force microscopic study, the GaN template with the SSL-inserted structure shows a signicant reduction in pit density compared to the conventionally-grown template. The insertion of the SSL is also found to alleviate the eect of threading dislocations on the degradation of the electrical performance and promotes the stability of the K-factor and a low thermal resis- tance under a long-term acceleration test. A relatively higher optical output power is obtained for SSL-inserted InGaN/GaN green LEDs at high injection currents. We report an amelioration of the electrical, thermal and optical performances of green InGaN/GaN multiple-quantum-well light-emitting diodes (LEDs) with AlGaN/GaN short- superlattice (SSL)-inserted structure grown using metal-organic chemical vapor deposition. Ac- cording to an atomic force microscopic study, the GaN template with the SSL-inserted structure shows a signicant reduction in pit density compared to the conventionally-grown template. The insertion of the SSL is also found to alleviate the eect of threading dislocations on the degradation of the electrical performance and promotes the stability of the K-factor and a low thermal resis- tance under a long-term acceleration test. A relatively higher optical output power is obtained for SSL-inserted InGaN/GaN green LEDs at high injection currents.

      • KCI등재

        Fast kinetics and high adsorption capacity of green extract capped superparamagnetic iron oxide nanoparticles for the adsorption of Ni(II) ions

        K. Nithya,Asha Sathish,P. Senthil Kumar,T. Ramachandran 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.59 No.-

        Superparamagnetic iron oxide nanoparticles were synthesized using co-precipitation technique by dissolving required stoichiometric proportions (1:2) of Fe2+ and Fe3+ salts in water. Lantana camara extract and ammonia solution were used as the stabilizing and precipitating agents, respectively. The prepared particles were characterized using FTIR, TGA, PSA, SEM–EDAX and zeta potential analysis. This material was successfully adopted for the removal of Ni(II) ions from aqueous solution and the process parameters were optimized. The results indicated the faster kinetics and a remarkably higher adsorption capacity of 227.20 mg/g at a pH of 6.0 and an adsorbent dose of 0.05 g.

      • KCI등재후보

        Cardioprotective Effect of Squalene on Lipid Profile in Isoprenaline-Induced Myocardial Infarction in Rats

        R. Anandan,K.H. Sabeena Farvin,S. Hari Senthil Kumar,K.S. Shiny,Suseela Mathew,T.V. Sankar,P.G. Viswanathan Nair 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.4

        We studied the cardioprotective effect of squalene on isoprenaline-induced myocardial infarction in male al-bino rats with respect to changes in the levels of lipid components in plasma and heart tissue. Prior administration of 2% squa-lene in feed for 45 days significantly reduced the isoprenaline-induced elevation in the levels of cholesterol, triglycerides, andfree fatty acids in plasma and heart tissue of rats following myocardial infarction. It exerted an anitlipidemic effect by re-ducing the level of low-density lipoprotein cholesterol with a parallel rise in the level of high-density lipoprotein cholesterolin plasma of experimental rats. A tendency to prevent the isoprenaline-induced depletion of phospholipids in the myocardiumof experimental rats was also observed. In the present study, the pretreatment with squalene significantly counteracted the iso-prenaline-induced lipid peroxidation and maintained the rats at near normal status. The results of the present study indicatethat the overall cardioprotective effect of squalene is probably related to an inhibition of lipid accumulation by its hypolipi-demic properties and/or its antioxidant properties.

      • Ellagic acid normalizes mitochondrial outer membrane permeabilization and attenuates inflammation-mediated cell proliferation in experimental liver cancer.

        Srigopalram, S,Jayraaj, I A,Kaleeswaran, B,Balamurugan, K,Ranjithkumar, M,Kumar, T Senthil,Park, J I,Nou, I S Humana Press 2014 Applied biochemistry and biotechnology Vol.173 No.8

        <P>Despite great advances in our understanding of the molecular causes of liver cancer, significant gaps still remain in our knowledge of the disease pathogenesis and development of effective strategies for early diagnosis and treatment. The present study was conducted to evaluate the chemopreventive activity of ellagic acid (EA) against experimental liver cancer in rats. This is the first report that implies a possible role of EA in controlling liver cancer through activation of mitochondrial outer membrane permeability via activating proteins such as Bax, bcl-2, cyt-C, and caspase-9, which play important roles in apoptosis. Downregulation of NF-κB, cyclin D1, cyclin E1, matrix metalloproteinases (MMP)-2, MMP-9, and proliferating cell nuclear antigen (PCNA) were noted in EA-treated experimental rats and controlled inflammation mediated liver cancer when compared to the diethylnitrosamine (DEN)-induced group. Transmission electron microscopy (TEM) analysis of the livers of experimental rats demonstrated that EA treatment renovated its internal architecture. Overall, these results demonstrate the value of molecular approaches in identifying the potential role of EA as an effective chemopreventive agent.</P>

      • SCISCIESCOPUS

        Selective methane production from visible-light-driven photocatalytic carbon dioxide reduction using the surface plasmon resonance effect of superfine silver nanoparticles anchored on lithium titanium dioxide nanocubes (Ag@Li<sub>x</sub>TiO<sub>2</sub>)

        Do, Jeong Yeon,Chava, Rama Krishna,Mandari, Kotesh Kumar,Park, No-Kuk,Ryu, Ho-Jung,Seo, Myung Won,Lee, Doyeon,Senthil, T.S.,Kang, Misook Elsevier 2018 Applied Catalysis B Vol.237 No.-

        <P><B>Abstract</B></P> <P>This study focused on the results of applying the strong surface plasmon resonance (SPR) effect of silver (Ag) particles anchored on cubic phase Li<SUB>x</SUB>TiO<SUB>2</SUB> to the carbon dioxide (CO<SUB>2</SUB>) photoreduction reaction. The study demonstrated the importance of three aspects: First, the cubic TiO<SUB>2</SUB>, which activated the [101] facet, was successfully produced. Secondly, Li<SUP>+</SUP> ions were introduced as Frenkel defects in some lattices to create oxygen defects. These vacancies increased the adsorption of carbon dioxide and sped up the rate-determining step in the CO<SUB>2</SUB> reduction reaction. In other words, they induced the easy conversion of CO<SUB>2</SUB> to CO, which is the first reduction product. Finally, the loading of Ag nanoparticles onto the Li<SUB>x</SUB>TiO<SUB>2</SUB> cubic surface the improved photocatalytic activity through SPR effects, and in particular led to selective conversion of CO<SUB>2</SUB> to methane (CH<SUB>4</SUB>). Quantitatively, the yield of CH<SUB>4</SUB> from CO<SUB>2</SUB> using the Ag@Li<SUB>0.075</SUB>TiO<SUB>2</SUB> particles was 49 μmol/g after 10 h of reaction, which was 8.2 and 1.5 times higher than that of cubic TiO<SUB>2</SUB> (6 μmol/g) and Li<SUB>0.075</SUB>TiO<SUB>2</SUB> (33 μmol/g) under UV-light. Additionally, its activity did not decrease under visible lights of 420 and 620 nm with the similar CH<SUB>4</SUB> yields of 42 and 34 μmol/g after 10 h, respectively. In particular, the production ratio of CH<SUB>4</SUB> and CO using cubic TiO<SUB>2</SUB> and Li<SUB>x</SUB>TiO<SUB>2</SUB> were about 1:1, with no selectivity for either product. However, after metallic Ag nanoparticles were loaded, the product selectivity shifted towards CH<SUB>4</SUB>, and the product ratio of CH<SUB>4</SUB> to CO was about 3:1. Furthermore, the Ag@Li<SUB>0.075</SUB>TiO<SUB>2</SUB> particles exhibited a strong SPR effect (in particular, direct electron transfer), which contributed to maintaining the charge separation and the lifetime of the catalyst over a long period. Catalytic deactivation was not observed during five cycles of recycling tests.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cubic TiO<SUB>2</SUB> activated the [101] facet was successfully synthesized. </LI> <LI> Li<SUP>+</SUP> addition made oxygen defects in some lattices. </LI> <LI> Ag particles anchored on cubic phased Li<SUB>x</SUB>TiO<SUB>2</SUB>. </LI> <LI> Ag@Li<SUB>x</SUB>TiO<SUB>2</SUB> improved photocatalytic activity, and produced selectively methane. </LI> <LI> Ag@Li<SUB>0.075</SUB>TiO<SUB>2</SUB> exhibited a strong SPR effect in particular direct electron transfer. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Selective methane production from visible-light-driven photocatalytic carbon dioxide reduction using the surface plasmon resonance effect of superfine silver nanoparticles anchored on lithium titanium dioxide nanocubes (Ag@Li<SUB>x</SUB>TiO<SUB>2</SUB>).</P> <P>[DISPLAY OMISSION]</P>

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