파킨슨 증후군을 동반한 조발형 알쯔하이머병 1예

최은정,방현,임주혁,이재홍 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.1

Extrapyramidal signs (EPSs) frequently accompany Alzheimer's disease(AD). However, the pathogenesis or pathologic basis for the EPSs in AD remains unclear. We report a case of presenile onset progressive dementia later associated with hemiparkinsonism. Brain biopsy showed neurofibrillary tangles and amyloid plaques. compatible with Alzheimer's disease. There are a few report about dopamine transporter imaging of AD with EPSs. 1-123 IPT SPECT revealed a decreased uptake in both basal ganglia, more severe on the left side and in the caudal putamen, which is consistent with the finding of idiopathic Parkinson's disease. Alzheimer's disease and Parkinson's disease are thought to be coexistent in our patient.

수평 매복된 상악 견치의 교정적 견인

최형준,이종은,이제호,이종갑 大韓小兒齒科學會 2003 大韓小兒齒科學會誌 Vol.30 No.4

치아 매복은 구강점막이나 악골내에서 치아의 맹출이 중지된 상태를 의미하며, 제 3구대구치와 상악 견치에서 호발한다. 상악 견치의 매복은 주로 측절치가 상실되거나 왜소한 경우와 연관성이 높지만 치배의 위치 이상과 같이 유전적인 요소와도 관련될 수 있다. 매복치는 심미적, 기능적으로 여러 가지 문제점을 야기하므로 조기에 진단하여 치료하는 것이 중요하며, 매복치의 상태에 따라서 치료 방법을 적절하게 선택하여야 한다. 본 증례는 11세 여아에서 구개측으로 수평 매복된 상악 우측 견치의 치료를 보고한 것으로, 매복치는 외과적 수술을 동반한 교정적 견인 방법을 사용하여 기능적, 심미적으로 회복되었다. 견인 치료는 매복 견치의 맹출 공간을 확보하면서 이루어졌으며, 치료 종료 후 매복 견치는 치근 흡수와 같은 합병증 없이 적절한 부착치은을 확보하여 양호하게 위치되었다. Tooth impaction is defined as a cessation of the eruption of a tooth at the level of the oral mucosa or alveolar bone. Maxillary canines are the most frequently impacted teeth next to the third molar. Maxillary canine impaction is associated with congenital missing of lateral incisors, peg lateralis and genetic factors such as ectopic positioning of a tooth germ. The clinicians have an important role in early detectionof tooth impaction for prevention of esthetic and functional problems. There are specific methods to treat impacted tooth for different conditions. In this case, an 11-year-old girl with a horizontally impacted maxillary right canine in a palatal position was treated through orthodontic traction along with surgical button attachment procedure. On regaining of eruption space, canine traction was performed. At the completion of treatment, the canine was positioned fairly within the arch with proper keratinized gingiva and complications such as root resorption were not observed.

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.

비중격 천공이 없는 크롬 노출 근로자에서의 후각장해에 관한 연구

최재욱,이성희,최연국,이은일,김해준 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : The chrome-induced olfactory alterations is caused by inhalation of chromic acid, a highly corrossive and toxic materials. And nasal septum perforation (NSP) has been suspected with possible causative factor of olfactory alterations. To our knowledge, there has been no report of the detailed findings of the olfactory alterations in chrome exposed subjects without nasal septum perforation (NSP). So we present the results of olfactory function test measured by T&T olfactometer and olfactometer perception test among chromium exposed workers without NSP. Methods : We performed this study in 25 study subjects and 25 control subjects matched with age, alcohol and smoking. All of subjects are man. We performed olfactory function test measured by T&T olfactometer and olfactometer perception test. Results : 1) The age distribution of the subjects involved in this study was from 20 to 54 years old (average 33.3 years old) and the mean duration exposed to chromium was from 64.9 months. 2) The olfactory function was checked by detection and recognition thresholds in five odorants. The detection thresholds of exposed group dealing with chromium were significantly increased in A and B ordorants than nonexposed group. The recognition thresholds of exposed group were significantly increased in D ordorants than nonexposed group. 3) The mean threshold of olfactometer perception test of exposed group were more increased than nonexposed group. But thresholds difference did not show statistical significance. 4) The detection thresholds of A and D ordorants, recognition threshold of C ordorants and thresholds of olfactometer perception test were increased in the relation with duration of chrome exposure. Conclusions : There has been no remarkable alterations in olfactory sense (T&T olfactometer and Olfactometer Perception Test) in subjects without nasal septum perforation (NSP) exposed to chromic acid.

甘草엑스의 抗炎 및 抗潰瘍作用에 대한 機轉

殷載淳,崔東晟,全焄,安文生 又石大學校 1989 論文集 Vol.11 No.-

Glycyrrhizae radix, commonly called licorice, has been used as anti-ulcerous and anti-inflammatory agents. It's main component, glycyrrhizin, is known to be effective as an anti-allergenic, anti-hepatic, and anti-viral agent, and shows steroid-like action. Histamine mediates and modulates inflammation through a variety of immuno-regulatory actions and stress-induced secretion of glucocorticoids(GC) is generally mediated by release of ACTH from the pituitary gland. This study was to investigate the mechanism of Glycyrrhizae Radix Ext. on anti-inflammatory and anti-ulcerous action. 1. The serum histamine contents was the most increased at the dose of 25㎍/㎏ LPS. injected rats(i.p), and the serum corticosterone was not significant. 2. Pretreatment of Glycyrrhizae radix Ext. (150㎎/㎏) was markedly decreasing the levels of serum histamine and corticosterone. 3. The serum histamine content was significantly increased in 120 minutes after LPS. injection. 4. The serum histamine content was decreased by pretreatment of cimetidine (H^2- receptor antagonist) 5㎎/㎏. These results were suggested that the effects of Glycyrrhizae Radix Ext, on anti-inflammatory and anti-ulcerous action was induced by its glucocorticoid-like action and inhibition of the histamine realese via H_2-receptor.

體育特技者의 肺機能과 運動後 恢復期의 血液가스의 變化

崔圭澤,朴載植,黃樹寬,朱永恩 慶北大學校 1985 論文集 Vol.39 No.-

The pulmonary function and changes of blood gas tensions and pH in the athletes have been reported but are fragmentary as to require more complete studies including all the pulmonary parameters and blood gas tensions especially at the early part of 20 years of age. This study was aimed to elucidate the pulmonary function at the rest and the changes of venous blood gas tension and pH after the exercise in the athletes of physical education students. The subjects chosen for this study were 15 athletes of physical education students (special group) of 21-25 years of age. The athletes had at least four years of exercise careers, and were compared with 12 non-athletes of physical education students (general group) who had not been subjected to any form of rigorous training program. All the subject were directed to perform running on the treadmill for three minutes under the condition of 15% grade and 5 MPH. The venous blood samples were taken at the rest as well as at 0, 5, 10 and 20 minutes after the exercise to check the changes of Pco_2, Po_2 and pH during the recovery period. The venous blood Pco_2, Po_2 and pH were determined using the Model 175 Automatic Blood Gas Analyzer by Corning Co., and the pulmonary function using the computerized spirometer. The results obtained were compared with the general group and summarized as follows: The special group exhibited higher values of the pulmonary function except FVC compared with the general group, and particularly FEV_0·5% and FEV_1% were significantly different. The venous Po_2 was decreased immediately after the exercise, but increased during the recovery period. The special group generally showed higher oxygen partial pressure than the general group. The venous Pco_2 in contrast to the oxygen increased immediately after the exercise, but decreased during the recovery period. The special group showed lower carbon dioxide partial pressure. Blood pH was significantly decreased from the resting value after the exercise and returned to the resting value at 20 minutes. In the special group, however, the change of pH was less than in the general group.

혼합치열기 반대교합자에서 상악골 전방견인장치를 이용한 치료증례

최형준,이제호,최병재,김은영 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.3

The prevalence of class Ⅲ malocclusion is approximately 5∼9%, and about one fourth of this malocclusion is due to underdeveloped maxilla. Maxillary protraction appliance is an orthopedic device which promote the growth of a deficient maxilla by applying extraoral force to actively growing patients. The object of using maxillary protraction appliance is to guide a normal growth of maxilla and mandible and improve the occlusal relationship and also improve the facial profile. The author treated three patients whom were diagnosed as a class Ⅲ malocclusion due to deficient maxilla using maxillary protraction appliance and the followings are the conclusions : 1. In these cases, anterior crossbite was corrected by anterior movement of maxilla and downward backward rotation of mandible and simultaneously, anterior facial height was increased. 2. The amount of dental change compare to skeletal change was greater as the patients got older. 3. When 500gm of force to each side was applied, the treatment period has been decreased. 4. As a result of applying the force between maxillary first primary molar and canine, there was a small degree of changes in palatal plane. So, it can be concluded that the maxillary protraction appliance is effective in treating growing patients with a deficient maxilla.

시비량이 생강의 생육 및 수량에 미치는 영향

최재을,김정선,이은정,이완재 충남대학교 농업과학연구소 1998 농업과학연구 Vol.25 No.2

This experiment was carried out to define the effects of application amounts of the chemical fertilizers on plant growth and yield of the ginger. The results obtained are summarized as follows. Plant height of the ginger was 45.3 cm at lower level of fertilizer, 52.6 cm at recommended level, and 49.4 cm at higher level. Leaf area, stem number, and stem diameter were more significantly increased at higher level of fertilization compared to recommended rate. Dry weight of shoots and rhizomes were significantly increased with the increase of fertilization level. Stem number, stem diameter, leaf area, dry weight of shoots, and fresh weight of rhizomes were positively correlated with the amounts of fertilizer applied. Yield of rhizomes were 1, 653 kg at lower level of fertilizer, 2,248 kg at recommended level and 2,428 kg at higher level, respectively. Ginger yield showed 7.4% higher at higher level of fertilization compared to recommended rate.

밀레니엄 광고세대의 커리어 행로(carrer path)에 관한 문헌연구

최은하,김재영 남서울대학교 2004 남서울대학교 논문집 Vol.10 No.1

This paper aims at study of the career path that is the most important decision factor of millennium generation's lifestyle. Because millennium generation will be new market indicator, of 21 century. For this study, this paper is based on generation Gap that is dealt with all social science. Where Traditionalists seek to build lifetime careers, Boomers to build stellar careers, and Xers to build portable careers, the career path ClashPoint for Millennials will be around parallel careers. Millennials' programmed live have made them true multitaskers. Millennials are already quite capable of learning several jobs simultaneously and performing them admirably. Millennials are throwing out the old model that you're either a waitress, a hostess, or running the register. In a tight labor market, making sure scarce Millennials can cover more than one position is a smart strategy. In a contracting economy, it's cost-effective to put Millennials' multitasking abilities to use rather than hire more employees. Plus, cross-training is a great retention strategy, which reduces the expense of turnover. Futurists predict that Millennials will experience as many as ten career changes in their lifetimes. That's career changes, not job changes-meaning they will recycle their skills and talents and personal preferences into new application again and again and again. Throughout their careers, this generation will be ready, willing, and able to adapt to an organization's evolving structure.

租稅에 의한 所得再分配效果의 有效性

崔壬煥,李載殷 成均館大學校 韓國産業硏究所 1981 韓國經濟 Vol.9 No.-