http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Chen Jiang,Jialei Huang,Zhenyu Jiang,Dabing Qian,Xiaolan Hong 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.1
Reducing energy use is a major consideration in green manufacturing. Ultrasonic vibration has the advantage of improving machining performance. This work presents an experimental investigation on magnetic compound fluid (MCF) polishing with and without ultrasonic vibration and estimates reductions in polishing energy consumption and surface roughness due to ultrasonic vibration during the machining process. A series of ultrasonic vibration-assisted MCF polishing (UVAMP) tests was carried out for brass H62, and the normal and tangential polishing forces, surface roughness and material removal rate of the traditional MCF polishing (MP) and UVAMP of brass were investigated for various machining parameters. The polishing energy consumptions during traditional MCF polishing and UVAMP were calculated and analyzed from the perspective of the energy of the polishing process. Results indicate that the use of UVAMP considerably reduces energy consumption and surface roughness during the polishing of brass. The adoption of UVAMP therefore has the potential to improve the efficiency and quality of polishing processes and offers a practical solution for the greener manufacturing of brass.
Zhenyu Xu,Ke Li,Kui Zhou,Shuiyuan Li,Hongwei Chen,Jiaqi Zeng,Rugang Hu 한국섬유공학회 2023 Fibers and polymers Vol.24 No.1
Silk Fibroin (SF) is a protein polymer with great biocompatibility, which can promote cell proliferation and differentiation,and enhance bone repair. In this paper, the effects of distinctive concentrations of SF solutions on the physicochemical andbiological properties of the SF-HA-SA scaffolds were investigated. The SF-HA-SA porous scaffolds were prepared utilizingthe pneumatic extrusion 3D printing technique, composed of hydroxyapatite (HA) and different concentrations of SF solution,and sodium alginate (SA) as a binder. The results shown the SF-HA-SA scaffolds can promote cell proliferation withthe increase of SF concentration in scaffolds, and the strength meets the necessities of trabecular bone defects of bone andcartilage repair. It provides an important reference for the application of SF in bone tissue engineering.
Zhenyu Ou,Yongjie Wang,Jinbo Chen,Le Tao,Li Zuo,Deepak Sahasrabudhe,Jean Joseph,Long Wang,Shuyuan Yeh 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
Although early studies suggested that bladder cancer (BCa) is more prevalent in men than in women, muscle-invasive rates are higher in women than in men, suggesting that sex hormones might play important roles in different stages of BCa progression. In this work, we found that estrogen receptor beta (ERβ) could increase BCa cell proliferation and invasion via alteration of miR-92a-mediated DAB2IP (DOC-2⁄DAB2 interacting protein) signals and that blocking miR- 92a expression with an inhibitor could partially reverse ERβ-enhanced BCa cell growth and invasion. Further mechanism dissection found that ERβ could increase miR-92a expression at the transcriptional level via binding to the estrogen-response-element (ERE) on the 5′ promoter region of its host gene C13orf25. The ERβ up-regulated miR-92a could decrease DAB2IP tumor suppressor expression via binding to the miR-92a binding site located on the DAB2IP 3′ UTR. Preclinical studies using an in vivo mouse model also confirmed that targeting this newly identified ERβ/miR-92a/ DAB2IP signal pathway with small molecules could suppress BCa progression. Together, these results might aid in the development of new therapies via targeting of this ERβ-mediated signal pathway to better suppress BCa progression.
Double-Blind Compact E-cash from Bilinear Map
Jiyang Chen,Bin Lian,Yongjie Li,Jialin Cui,Ping Yu,Zhenyu Shu,Jili Tao 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.4
Compact E-cash is the first scheme which can withdraw 2l coins within (1) operations and then store them in ( ) bits. Because of its high efficiency, a lot of research has been carried out on its basis, but no previous research pay attention to the privacy of payees and in some cases, payees have the same privacy requirement as payers. We propose a double-blind compact E-cash scheme, which means that both the payer and the payee can keep anonymous while spending. In our scheme, the payer and the bank cannot determine whether the payees of two different transactions are the same one and connect the payee with transactions related to him, in this way, the privacy of the payee is protected. And our protocols disconnect the received coin from previous transaction, then, the coin can be transferred into an unspent coin which belongs to the payee. The proposed e-cash scheme is secure within y-DDHI and LRSW assumption.
IL-17A Secreted by Th17 Cells Is Essential for the Host against Streptococcus agalactiae Infections
( Jing Chen ),( Siyu Yang ),( Wanyu Li ),( Wei Yu ),( Zhaowei Fan ),( Mengyao Wang ),( Zhenyue Feng ),( Chunyu Tong ),( Baifen Song ),( Jinzhu Ma ),( Yudong Cui ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.5
Streptococcus agalactiae is an important bacterial pathogen and causative agent of diseases including neonatal sepsis and meningitis, as well as infections in healthy adults and pregnant women. Although antibiotic treatments effectively relieve symptoms, the emergence and transmission of multidrug-resistant strains indicate the need for an effective immunotherapy. Effector T helper (Th) 17 cells are a relatively newly discovered subpopulation of helper CD4<sup>+</sup> T lymphocytes, and which, by expressing interleukin (IL)-17A, play crucial roles in host defenses against a variety of pathogens, including bacteria and viruses. However, whether S. agalactiae infection can induce the differentiation of CD4<sup>+</sup> T cells into Th17 cells, and whether IL-17A can play an effective role against S. agalactiae infections, are still unclear. In this study, we analyzed the responses of CD4<sup>+</sup> T cells and their defensive effects after S. agalactiae infection. The results showed that S. agalactiae infection induces not only the formation of Th1 cells expressing interferon (IFN)-γ, but also the differentiation of mouse splenic CD4<sup>+</sup> T cells into Th17 cells, which highly express IL-17A. In addition, the bacterial load of S. agalactiae was significantly increased and decreased in organs as determined by antibody neutralization and IL-17A addition experiments, respectively. The results confirmed that IL-17A is required by the host to defend against S. agalactiae and that it plays an important role in effectively eliminating S. agalactiae. Our findings therefore prompt us to adopt effective methods to regulate the expression of IL-17A as a potent strategy for the prevention and treatment of S. agalactiae infection.
Design and Implementation of a Novel Horizontal AFM Probe Utilizing a Quartz Tuning Fork
Yifu Chen,Yingzi Li,Guanqiao Shan,Yingxu Zhang,Zhenyu Wang,Mubing Wang,Hua Li,Jianqiang Qian 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.1
This paper presents a new structure of a novel horizontal atomic force microscope probe utilizing a quartz tuning fork. The horizontal structure exhibits high resistance to environmental noise, and thus the probe can maintain good stability throughout the imaging work. The quartz tuning fork, which is utilized as a force sensor due to its simple mechanical structure and self-actuating and self-sensing characteristics, can significantly simplify the mechanical structure of the probe. The probe is divided into three parts: an approximation device, a force sensor, and a three-dimensional scanner. Each part is carefully designed to guarantee the imaging performance. It is verified that the proposed horizontal AFM probe is stable by conducting finite-element analysis, including modal analysis and noise analysis. Furthermore, the probe is fabricated and the experiments are performed to verify its stability. The proposed horizontal AFM probe combined with the existing control system in the frequency modulation succeeds in imaging within 25 μm × 25 μm and 20 μm × 20 μm ranges stably.