반영웅소설(反英雄小說)의 서사적 특성 연구

김유진 ( Kim¸ Yujin ) 한국고소설학회 2020 古小說 硏究 Vol.49 No.-

영웅소설 유형은 영웅의 일대기를 중심으로 설명되었다. 본고에서는 영웅의 일대기라는 구성의 문제에서 나아가 영웅이라는 인물 유형이 지닌 변별적 자질을 통해 영웅소설의 세부 분류를 시도하였다. 〈최고운전〉, 〈전우치전〉, 〈홍길동전〉처럼 영웅소설 가운데 예외적 특징을 보이는 작품들의 주인공을 반영웅(反英雄, Anti-Hero)의 인물유형으로 분류하고 이들 작품의 서사가 보여주는 특성을 추출해보았다. 그 결과 반영웅소설 유형을 새롭게 제안할 수 있었다. 반영웅소설의 서사는 자식 살해라는 가부장제의 극단적 폭력성을 보여주는 한편, 국가 지배 권력의 무능력을 고발하는 것이었다. 나아가 반영웅소설의 서사는 국가 간 관계에 있어서 대국(大國)과 소국(小國)의 불평등한 관계의 문제를 비판하는 한편 대등한 국가 간 관계에 대한 고민을 보여주기도 하였다. 이러한 반영웅 인물 유형과 반영웅소설은 새로운 작품 유형으로 제안될 수 있다. So far, the type of heroic novel has been described about the hero's biographical story. This paper tried to classify heroic novels in detail through the distinctive feature of the heroic character type in addition to the problem of the composition of the hero's biographical narratives. The protagonist of the heroic novels such as Choe-go-un-jeon, Jeon-u-cu-jeon, and Hong-gil-dong-jeon were classified as the type of characters of Anti-Hero and these pre-modem novels extracted the characteristics of the narratives of Anti-Heroic novels. As a result, this paper could suggest to call this type of novels as Anti-Hervic novels. The main character of the Anti-Hero novels and these narratives were to show the extreme violence of the patriarchal system of killing children, while accusing the incompetence of national governance. Furthermore, the narrative of the Anti-Heroic novel criticized the unequal relationship between the great and small nations in the international relations, while also showing concerns about equal relations between the nations. These Anti-Heroic characters and Anti-Heroic novels can be categorized into a group of pre-modern novels.

열처리 및 나이신ㆍ유카추출물 첨가에 의한 김치의 미생물 증식 저해

김지선(Ji Sun Kim),김유진(Yujin Kim),박정미(Jung-Mi Park),김태집(Tae-Jip Kim),김범수(Beom Soo Kim),김연미(Yeon Mi Kim),김혜림(Hye Rim Kim),한남수(Nam Soo Han) 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.11

본 실험은 김치의 유통기한을 연장하고자 배추김치에 열처리 및 천연보존료를 첨가하여 그 효과를 조사하였다. 400g의 배추김치를 각각 원형 polyethylene 플라스틱 용기에 담고 90℃에서 120분 처리하였을 때, 2.0 log₁?CFU/g만큼 총균수가 감소하였으나 열처리 10분 만에 용기의 변형이 일어났고, 김치의 관능변화가 감지되어 부적절한 조건으로 판정되었다. 필름 파우치에 김치를 옮겨 열처리하였을 때는 80℃에서 30분 이하로 열처리하였을 때 0.3 log₁?CFU/g의 저해효과를 보여 효과는 크지 않았지만 김치의 관능변화를 일으키지 않는 적정조건이었다. 반면에, 배추 조직의 느린 열전달과 열처리 시 관능 변화 특성을 고려하여 김치 부재료 양념을 절임배추와 혼합 전 별도 열처리를 실시한 결과, 80℃ 이하에서 30분 열처리하였을 때 총 균수를 0.5 log₁?CFU/g, 그리고 유산균을 1.0 log₁?CFU/g만큼 저해하여 배추김치 살균보다도 더 효과적인 방법으로 판명되었다. 또한, 나이신과 유카추추물을 첨가한 김치를 한 달간 저장하며 미생물의 저해 효과를 확인한 결과 5℃에 보관할 때에 두 처리구 모두 저장기간 동안 유산균의 생육을 저해하는 효과를 보였다. 나이신과 유카추출물의 경우 모두 낮은 온도에서(5℃) 높은 초기 미생물의 저해 효과를 보였다. 이 연구 결과는 저온 살균법의 물리적 방법과 나이신 또는 유카추출물과 같은 천연보존료를 사용하는 화학적방법이 각각 김치의 초기 미생물을 감소시키고 유통기간 동안 미생물의 생육속도를 저해하는데 효과적임을 보여준다. For extension of storage period of cabbage-kimchi, effects of heat treatment as well as nisin or yucca extract were examined on the growth of microbes. Firstly, when kimchi was heated at various temperatures in polyethylene plastic bottle or membrane pouch, the optimum inhibitory condition giving no sensory change was at 80℃ for 30 min in a plastic membrane pouch and this treatment made a reduction of 0.3 log₁?CFU/g in total microbes. The result showed that use of plastic bottle was inefficient due to low heat transfer rate. Interestingly, pasteurization of seasoning pastes at 80℃ for 30 min separately from cabbage resulted in better inhibitory effect reducing 0.5 log₁?CFU/g of total bacteria and 1.0 log₁?CFU/g of lactic acid bacteria, and this operation was regarded as a promising inhibitory method. Secondly, when nisin and yucca extract were separately added in kimchi, microbial growth was inhibited during storage period and their inhibition effects were enhanced at lower temperature.

Ameliorating effects of Mango ( <i>Mangifera indica</i> L.) fruit on plasma ethanol level in a mouse model assessed with ¹ H-NMR based metabolic profiling

Kim, So-Hyun,K. Cho, Somi,Min, Tae-Sun,Kim, Yujin,Yang, Seung-Ok,Kim, Hee-Su,Hyun, Sun-Hee,Kim, Hana,Kim, Young-Suk,Choi, Hyung-Kyoon the Society for Free Radical Research Japan 2011 Journal of clinical biochemistry and nutrition Vol.48 No.3

<P>The ameliorating effects of Mango (<I>Mangifera indica</I> L.) flesh and peel samples on plasma ethanol level were investigated using a mouse model. Mango fruit samples remarkably decreased mouse plasma ethanol levels and increased the activities of alcohol dehydrogenase and acetaldehyde dehydrogenase. The <SUP>1</SUP>H-NMR-based metabolomic technique was employed to investigate the differences in metabolic profiles of mango fruits, and mouse plasma samples fed with mango fruit samples. The partial least squares-discriminate analysis of <SUP>1</SUP>H-NMR spectral data of mouse plasma demonstrated that there were clear separations among plasma samples from mice fed with buffer, mango flesh and peel. A loading plot demonstrated that metabolites from mango fruit, such as fructose and aspartate, might stimulate alcohol degradation enzymes. This study suggests that mango flesh and peel could be used as resources for functional foods intended to decrease plasma ethanol level after ethanol uptake.</P>

Virus-Based Structural Color Sensor for the Endocrine Disrupting Chemicals Detection

Yujin Lee,Ye-Ji Kim,Thanh Mien Nguyen,Yeong Ju Lee,You Hwan Kim,Seung Su Jeong,Jae Suk Yoon,Na Yeung Kim,Jun Su Choi,Min Soo Kim,Jin Jae Park,Suk Ho Lee,Eun Jung Choi,Jin-Woo Oh 한국고분자학회 2019 한국고분자학회 학술대회 연구논문 초록집 Vol.44 No.2

The combination of ursolic acid and leucine potentiates the differentiation of C2C12 murine myoblasts through the mTOR signaling pathway.

Kim, Minjung,Sung, Bokyung,Kang, Yong Jung,Kim, Dong Hwan,Lee, Yujin,Hwang, Seong Yeon,Yoon, Jeong-Hyun,Yoo, Mi-Ae,Kim, Cheol Min,Chung, Hae Young,Kim, Nam Deuk UNKNOWN 2015 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.35 No.3

<P>Aging causes phenotypic changes in skeletal muscle progenitor cells that lead to the progressive loss of myogenic differentiation and thus a decrease in muscle mass. The naturally occurring triterpene, ursolic acid, has been reported to be an effective agent for the prevention of muscle loss by suppressing degenerative muscular dystrophy. Leucine, a branched-chain amino acid, and its metabolite, 관-hydroxy-관-methylbutyric acid, have been reported to enhance protein synthesis in skeletal muscle. Therefore, the aim of the present study was to investigate whether the combination of ursolic acid and leucine promotes greater myogenic differentiation compared to either agent alone in C2C12 murine myoblasts. Morphological changes were observed and creatine kinase (CK) activity analysis was performed to determine the conditions through which the combination of ursolic acid and leucine would exert the most prominent effects on muscle cell differentiation. The effect of the combination of ursolic acid and leucine on the expression of myogenic differentiation marker genes was examined by RT-PCR and western blot analysis. The combination of ursolic acid (0.5 µM) and leucine (10 µM) proved to be the most effective in promoting myogenic differentiation. The combination of ursolic acid and leucine significantly increased CK activity than treatment with either agent alone. The level of myosin heavy chain, a myogenic differentiation marker protein, was also enhanced by the combination of ursolic acid and leucine. The combination of ursolic acid and leucine significantly induced the expression of myogenic differentiation marker genes, such as myogenic differentiation 1 (MyoD) and myogenin, at both the mRNA and protein level. In addition, the number of myotubes and the fusion index were increased. These findings indicate that the combination of ursolic acid and leucine promotes muscle cell differentiation, thus suggesting that this combination of agents may prove to be beneficial in increasing muscle mass.</P>

Brachybacterium kimchii sp. nov. and Brachybacterium halotolerans subsp. kimchii subsp. nov., isolated from the Korean fermented vegetables, kimchi, and description of Brachybacterium halotolerans subsp. halotolerans subsp. nov.

Yujin Kim,Yeon Bee Kim,Juseok Kim,Joon Yong Kim,Tae Woong Whon,Won-Hyong Chung,Eun-Ji Song,Young-Do Nam,Se Hee Lee,Seong Woon Roh 한국미생물학회 2022 The journal of microbiology Vol.60 No.7

Two Gram-stain-positive, oxidase-negative, catalase-positive, and coccus-shaped bacterial strains, designated CBA3104T and CBA3105T, were isolated from kimchi. Strain CBA3104T and CBA3105T grew at 10–35°C (optimum, 25°C and 30°C, respectively), at pH 6.0–8.5 (optimum, pH 6.5), and in the presence of 0–15% (w/v) NaCl (optimum, 5%). A phylogenetic analysis based on 16S rRNA gene sequences revealed that strain CBA3104T formed a distinct phylogenetic lineage within the genus Brachybacterium whereas strain CBA3105T was closely positioned with Brachybacterium halotolerans MASK1Z-5T. The 16S rRNA gene sequence similarity between strains CBA3104T and CBA3105T was 99.9%, but ANI and dDDH values between strains CBA3104T and CBA3105T were 93.61% and 51.5%, respectively. Strain CBA3104T showed lower ANI and dDDH values than species delineation against three closely related strains and type species of the genus Brachybacterium, however, strain CBA3105T showed 96.63% ANI value and 69.6% dDDH value with Brachybacterium halotolerans MASK1Z-5T. Among biochemical analysis results, strain CBA3104T could uniquely utilize bromo-succinic acid whereas only strain CBA3105T was positive for alkaline phosphatase and α-fucosidase among two novel strains, closely related strains, and type species of the genus Brachybacterium. Compared with strain CBA3105T and Brachybacterium halotolerans JCM 34339T, strain CBA3105T was differentially positive for acid production of D-arabinose, D-adonitol, and potassium 5-ketogluconate and enzyme activity of β-glucuronidase. Both strains contained menaquinone-7 as the dominant quinone. The cell-wall peptidoglycan of two novel strains contained meso-diaminopimelic acid. The major fatty acids of strains CBA3104T and CBA3105T were anteiso-C15:0, anteiso-C17:0, and iso-C16:0. The major polar lipids of both strains were phosphatidylglycerol and diphosphatidylglycerol. Strain CBA3104T possessed a uniquely higher abundance of tRNA (97 tRNAs) than four Brachybacterium strains used for comparative taxonomic analysis (54–62 tRNAs). Both the CBA3104T and CBA3105T strain harbored various oxidoreductase, transferase, hydrolase, and lyase as strain-specific functional genes compared to closely related strains and Brachybacterium type species. The results of biochemical/physiological, chemotaxonomic, and genomic analyses demonstrated that strains CBA3104T and CBA3105T represent a novel species of the genus Brachybacterium and a novel subspecies of B. halotolerans, respectively, for which the names Brachybacterium kimchii sp. nov. and B. halotolerans subsp. kimchii subsp. nov. are proposed. The type strains of the novel species and the novel subspecies are CBA3104T (= KCCM 43417T = JCM 34759T) and CBA3105T (= KCCM 43418T = JCM 34760T), respectively.

Dynamic Transcriptome Repertoire of Streptomyces coelicolor

Yujin JEONG,Giselda BUCCA,Emma LAING,Ji-Nu KIM,Min Woo KIM,Sun Chang KIM,Byung-Gee KIM,Colin P. SMITH,Byung-Kwan CHO 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.4

Overexpression of β-Catenin and Cyclin D1 is Associated with Poor Overall Survival in Patients with Stage IA-IIA Squamous Cell Lung Cancer Irrespective of Adjuvant Chemotherapy

Kim, Yujin,Jin, DongHao,Lee, Bo Bin,Cho, Eun Yoon,Han, Joungho,Shim, Young Mog,Kim, Hong Kwan,Kim, Duk-Hwan Elsevier 2016 JOURNAL OF THORACIC ONCOLOGY Vol.11 No.12

<P>Conclusions: The present study suggests that simultaneous overexpression of beta-catenin and cyclin D1 may be associated with poor overall survival irrespective of platinum-based adjuvant chemotherapy in stage IA-IIA squamous cell carcinoma of the lung. (C) 2016 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.</P>

Development of Key Performance Indicators for the Improvement of University Facility Management Services in Korea

Kim, Yujin,Kim, Min Soo,Kim, Jun Ha Informa UK (TaylorFrancis) 2018 JOURNAL OF ASIAN ARCHITECTURE AND BUILDING ENGINEE Vol.17 No.2

The SAM Domains of Anks Family Proteins Are Critically Involved in Modulating the Degradation of EphA Receptors

Kim, Jieun;Lee, Haeryung;Kim, Yujin;Yoo, Sooyeon;Park, Eunjeong;Park, Soochul 숙명여자대학교 여성건강연구소 2011 여성과 건강 Vol.6 No.2

We recently reported that the phosphotyrosine-binding (PTB) domain of Anks family proteins binds to EphA8,thereby positively regulating EphA8-mediated signaling pathways. In the current study, we identified a potential role for the SAM domains of Anks family proteins in EphA signaling. We found that SAM domains of Anks family proteins directly bind to ubiquitin, suggesting that Anks proteins regulate the degradation of ubiquitinated EphA receptors. Consistent with the role of Cbl ubiquitin ligases in the degradation of Eph receptors, our results revealed that the ubiquitin ligase c-Cbl induced the ubiquilinaiion and degradation of EphA8 upon ligand binding. Ubiquitinated EphA8 also bound to the SAM domains of Odin, a member of the Anks family proteins. More importantly, the overexpression of wild-type Odin protected EphA8 and EphA2 from undergoing degradation following ligand stimulation and promoted EphA-mediated inhibition of cell migration. In contrast,a SAM domain deletion mutant of Odin strongly impaired the function of endogenous Odin, suggesting that the mutant functions in a dominant-negative manner. An analysis of Odin-deficient primary embryonic fibroblasts indicated that Odin levels play a critical role in regulating the stability of EphA2 in response to ligand stimulation. Taken together,our studies suggest that the SAM domains of Anks family proteins play a pivotal role in enhancing the stability of EphA receptors by modulating the ubiquitination process.