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      • KCI등재

        Hybrid Evaluation Method for Dispatching Control Level of Smart Distribution Network

        Yu‑Qian Wang,Leijiao Ge,Na Zhang 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.6

        Smart distribution network (SDN) is an important part of smart grid (SG), and its dispatching control level is closely related to the safety and reliability of power system. In order to comprehensively and systematically evaluate the dispatching and control level of smart distribution network, this paper constructs an evaluation index system based on the considerations of reliability, economy, efectiveness, adaptability and cleanness. Taking into account the disadvantages of subjective weighting methods and the objective weighting methods, this paper puts forward a kind of subjective and objective mixed evaluation method for dispatching control level of SDN. In view of the great infuence of expert opinions of subjective weighting method and the high data dependence of objective weighting method, the binomial coefcient method of subjective weighting is combined with the multi-objective programming method of objective weighting to give weight to each index in the comprehensive evaluation index system of dispatching control level of SDN. Case studies verify the proposed method has great signifcance to the evaluation of the dispatching control level of SDN. It can efectively evaluate the dispatching level of SDN and provide a reference for the improvement of the dispatching control level of SDN.

      • KCI등재

        Phosphorylation of DYNLT1 at Serine 82 Regulates Microtubule Stability and Mitochondrial Permeabilization in Hypoxia

        Xue Xu,Yue-sheng Huang,Qiong Zhang,Jiong-yu Hu,Dong-xia Zhang2,Xu-pin Jiang,jie-zhi Jia,Jing-ci Zhu 한국분자세포생물학회 2013 Molecules and cells Vol.36 No.4

        Hypoxia-induced microtubule disruption and mitochondrial permeability transition (mPT) are crucial events leading to fatal cell damage and recent studies showed that microtubules (MTs) are involved in the modulation of mitochondrial function. Dynein light chain Tctex-type 1 (DYNLT1) is thought to be associated with MTs and mitochondria. Previously we demonstrated that DYNLT1 knockdown aggravates hypoxia-induced mitochondrial permeabilization, which indicates a role of DYNLT1 in hypoxic cytoprotection. But the underlying regulatory mechanism of DYNLT1 remains illusive. Here we aimed to investigate the phosphorylation alteration of DYNLT1 at serine 82 (S82) in hypoxia (1% O2). We therefore constructed recombinant adenoviruses to generate S82E and S82A mutants, used to transfect H9c2 and HeLa cell lines. Development of hypoxia-induced mPT (MMP examining, Cyt c release and mPT pore opening assay), hypoxic energy metabolism (cellular viability and ATP quantification), and stability of MTs were examined. Our results showed that phosph-S82 (S82-P) expression was increased in early hypoxia; S82E mutation (phosphomimic) aggravated mitochondrial damage, ele-vated the free tubulin in cytoplasm and decreased the cellular viability; S82A mutation (dephosphomimic) seemed to diminish the hypoxia-induced injury. These data suggest that DYNLT1 phosphorylation at S82 is involved in MTs and mitochondria regulation, and their interaction and cooperation contribute to the cellular hypoxic tolerance. Thus, we provide new insights into a DYNLT1 mechanism in stabilizing MTs and mitochondria, and propose a potential therapeutic target for hypoxia cytoprotective studies.

      • KCI등재

        Interactions between Endophytes and Plants: Beneficial Effect Endophytes to Ameliorate Biotic and Abiotic Stresses in Plants

        Yu Zhang,Xiaxia Yu,Wenjin Zhang,Duoyong Lang,Xiaojia Zhang,Gaochang Cui,Xinhui Zhang 한국식물학회 2019 Journal of Plant Biology Vol.62 No.1

        Endophytes are typically non-pathogenic microbesthat at some period in their life cycles colonize the interiorspaces of plant tissues. There is a growing interest in the roleof the endophytes in ameliorating various stresses on plants,including biotic stress (such as pathogenic microbes) andabiotic stress (such as drought and salt stress), becauseendophytes can produce phytohormones, fixing nitrogen,antagonistic substances, enzymes, which plays an importantrole in plants respond to biotic and abiotic stress. Previouslyresearchers have reviewed endophytes promote plant growththrough direct or indirect mechanisms. In order to furtherclarify the interactions between endophytes and it’s hostplants, we reviewed the biological properties of endophytesisolated from different parts of plant, the methods of plantinoculation with endophytes and the beneficial effects ofendophytes to mitigate biotic and abiotic stress in plants.

      • KCI등재
      • KCI등재

        The Evolution of Chinese New Media Research in 1998-2017—An Analysis Based on Science Mapping by CiteSpace

        Zhang, Tianrong,Li, Hongying,Zhang, Xiaoman,Zhao, Kun,Yu, Fangbo 부산대학교 중국연구소 2019 Journal of China Studies Vol.22 No.2

        This paper uses the visual analysis software-CiteSpace to analyze the 2, 076 related papers of “Key words=new media or new medium” in the CSSCI database from 1998 to 2017. It analyzes the research status and research hotspots of new media in China, and predicts the future development trend of new media, and provides reference for new media research and development in China. This research adopts the scientific metrology research methods, mainly including word frequency analysis, co-occurrence analysis, co-citation analysis and clustering analysis. The specific technical method is using CiteSpace to visualize the Science Mapping of paper datas, drawing up the Science Mapping of Chinese new media research from 1998 to 2017. The Science Mapping intuitively shows the law of paper growth, the source of paper, the contribution of authors and the characteristics of institutional distribution of Chinese new media research. It also analyses the research status, research hotspots and research frontiers of new media in China. There are seven main findings in this paper. First, papers of Chinese new media research increased slowly from 1998 to 2006, and began to flourish in 2007, reaching its peak in 2015. The index curve as a whole showed a straight upward trend, and it will continue to show a thriving development trend in the future. Second, new media research papers are mainly concentrated in news and communication journals, editing & publishing journals and educational comprehensive journals are also published. It has become an important part of the new media research field to study the influence of new media from the perspectives of journalism and communication, library and information science, pedagogy, sociology, art and other disciplines. Third, there are many High-yielding authors on new media research, such as Wang Xiwei, Huang Mingfen, Ji Haiju, Deng Xianglian and Kuang Wenbo. But they are widely distributed and have few cooperative networks. It can form a systematic and highly influential core research. Four, Yu Guoming, Penglan, Chen Lidan, Kuang Wenbo, Guo Qingguang and Ouyang Youquan are High-impact authors and high-cited authors in this field,Yu Guoming is an authoritative expert in new media. Five, the institutions with the highest papers of publications are Communication University of China, Renmin University of China, Fudan University and Jilin University in turn. There is a lack of cooperation and exchanges among institutions, which has not formed a large-scale cooperation network. Six, new media research mainly focuses on media convergence, network public opinion, the Internet, new media art, digital publishing, social media, WeChat, Weibo and other hot spots; media integration is the biggest research hotspot, betweenness centrality=0.62. Last,with the development of media technology, under the background of “Internet +”, “Artificial intelligence”, “Big data”, new media technology innovation, content innovation, government media image reshaping, network comsensus management,and educational information application will become the research frontiers of new media in the future.

      • SCIESCOPUSKCI등재

        Pathological Impact on the Phyllosphere Microbiota of Artemisia argyi by Haze

        ( Yu-zhu Zhang ),( De-yu Jiang ),( Chi Zhang ),( Kun Yang ),( Huai-fu Wang ),( Xiu-wen Xia ),( Wei-jun Ding ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.4

        The pathological impact of haze upon the phyllosphere microbiota awaits investigation. A moderate degree of haze environment and a clean control were selected in Chengdu, China. Artemisia argyi, a ubiquitously distributed and extensively applied Chinese herb, was also chosen for experiment. Total genome DNA was extracted from leaf samples, and for metagenome sequencing, an Illumina HiSeq 2500 platform was applied. The results showed that the gene numbers of phyllosphere microbiota derived from haze leaves were lower than those of the clean control. The phyllosphere microbiota derived from both haze and clean groups shared the same top ten phyla; the abundances of Proteobacteria, Actinomycetes and Anorthococcuso of the haze group were substantially increased, while Ascomycetes and Basidiomycetes decreased. At the genus level, the abundances of Nocardia, Paracoccus, Marmoricola and Knoelia from haze leaves were markedly increased, while the yeasts were statistically decreased. KEGG retrieval demonstrated that the functional genes were most annotated to metabolism. An interesting find of this work is that the phyllosphere microbiota responsible for the synthesis of primary and secondary metabolites in A. argyi were significantly increased under a haze environment. Relatively enriched genes annotated by eggNOG belong to replication, recombination and repair, and genes classified into the glycoside hydrolase and glycosyltransferase enzymes were significantly increased. In summary, we found that both structure and function of phyllosphere microbiota are globally impacted by haze, while primary and secondary metabolites responsible for haze tolerance were considerably increased. These results suggest an adaptive strategy of plants for tolerating and confronting haze damage.

      • Risk Factors for Cervical Cancer in Rural Areas of Wuhan China: a Matched Case-control Study

        Zhang, Bin,Zhou, Ai-Fen,Zhu, Chang-Cai,Zhang, Ling,Xiang, Bing,Chen, Zhong,Hu, Rong-Hua,Zhang, Ya-Qi,Qiu, Lin,Zhang, Yi-Ming,Xiong, Chao-Du,Du, Yu-Kai,Shi, Yu-Qin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

        Cervical cancer is a serious public health problem in developing countries. We investigated possible risk factors for cervical cancer in rural areas of Wuhan China using a matched case-control study with 33 women diagnosed with cervical cancer and 132 healthy women selected from the same area as matched controls. A questionnaire, which included questions about general demography conditions, environmental and genetic factors, the first sexual intercourse, first marriage age, age at first pregnancy, pregnancy first child's age, female personal health history, social psychological factors, dietary habits, smoking and alcohol status and other living habits was presented to all participants. At the same time, HPV infection of every participant was examined in laboratory testing. Results showed HPV infection (P<0.000, OR=23.4) and pregnancy first child's age (P<0.000, OR=13.1) to be risk factors for cervical cancer. Menopause (P=0.003, OR=0.073) was a protective factor against cervical cancer. However, there was no indication of associations of environmental (drinking water, insecticide, disinfectant) genetic (cancer family history), or life-style factors (smoking status, alcohol status, physical training, sleep quality), including dietary habits (intake of fruit and vegetable, meat, fried food, bean products and pickled food) or social psychological factors with cervical cancer. The results suggest that the risk of cervical cancer in Chinese rural women may be associated with HPV infection, menopause and the pregnancy first child's age.

      • KCI등재

        Food Microbiology and Biotechnology : Potential Probiotic Characterization of Lactobacillus plantarum Strains Isolated from Inner Mongolia “Hurood” Cheese

        ( Jian Zhang ),( Xue Zhang ),( Li Zhang ),( Yu Juan Zhao ),( Chun Hua Niu ),( Zhen Nai Yang ),( Sheng Yu Li ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.2

        Total 121 lactic acid bacteria were isolated from homemade Inner Mongolia extra hard Hurood cheese. Seven of these strains, identified as Lactobacillus plantarum, were studied for probiotic characteristics. All seven strains survived at pH 3.0 for 3 h, or in the presence of oxgall at 0.3% or 0.6% for 4 h, but their viabilities were affected to different extents at pH 2.0 for 3 h. Strains C37 and C51 showed better adherence to Caco-2 cells, and higher hydrophobicity. The seven L. plantarum strains were different in in vitro free radical scavenging activities and cholesterolreducing ability. In vivo evaluation of the influence of L. plantarum C37 on the intestinal flora in a mouse model showed strain C37 could increase the viable counts of lactobacilli in feces of mice and decrease the viable counts of enterococci. When L. plantarum C37 was used to prepare probiotic Hurood cheese, it was able to maintain high viable counts (>7.8 log CFU/g) during the whole storage period, but the composition of the cheese was not changed. These results indicate that L. plantarum C37 could be considered as a promising probiotic strain.

      • KCI등재

        A national survey on how to improve traditional Chinese medicine learning internationally: Perceptions from both teachers and students

        Zhu Yu-Hang,Yan Wu,Hao Zhang,Yanfei Zhao,Yule Ren,Wei Hu,Pan Li,Huiyi Wang,Ying Wang,Boda Zhang,Yujie Wang,Hongwen Yuan,Jiping Zhang,Wenqiang Li,Yufang Zhao,Jie Zhao,Yedong Shi,Yanye Shu,Xiao Zhang,Ya 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.4

        Background With the increasing popularity of traditional Chinese medicine (TCM) by the global community, how to teach basic knowledge of TCM to international students and improve the teaching quality are important issues for teachers of TCM. The present study was to analyze the perceptions from both students and teachers on how to improve TCM learning internationally. Methods A cross-sectional national survey was conducted at 23 universities/colleges across China. A structured, self-reported on-line questionnaire was administered to 34 Chinese teachers who taught TCM course in English and to 1016 international undergraduates who were enrolled in the TCM course in China between 2017 and 2021. Results Thirty-three (97.1%) teachers and 900 (88.6%) undergraduates agreed Chinese culture should be fully integrated into TCM courses. All teachers and 944 (92.9%) undergraduates thought that TCM had important significance in the clinical practice. All teachers and 995 (97.9%) undergraduates agreed that modern research of TCM is valuable. Thirty-three (97.1%) teachers and 959 (94.4%) undergraduates thought comparing traditional medicine in different countries with TCM can help the students better understand TCM. Thirty-two (94.1%) teachers and 962 (94.7%) undergraduates agreed on the use of practical teaching method with case reports. From the perceptions of the undergraduates, the top three beneficial learning styles were practice (34.3%), teacher's lectures (32.5%), case studies (10.4%). The first choice of learning mode was attending to face-to-face teaching (82.3%). The top three interesting contents were acupuncture (75.5%), Chinese herbal medicine (63.8%), and massage (55.0%). Conclusion To improve TCM learning among international undergraduates majoring in conventional medicine, integration of Chinese culture into TCM course, comparison of traditional medicine in different countries with TCM, application of the teaching method with case reports, and emphasization of clinical practice as well as modern research on TCM should be fully considered.

      • Exploring Appropriate Moral Education Methods in Literary Education in We-media Age

        Yujia ZHANG(Yujia ZHANG),Huan YU(Huan YU) 한국공공가치학회 2023 공공가치연구 Vol.5 No.-

        Purpose: Exploring appropriate moral education methods that adapt to the We-media age is an important task of literary education. In the context of We-media, literary education should aim at guiding the students to think over moral issues in specific situations on the basis of the aesthetic role of literature in order to promote their moral development. We-media have made communication convenient and efficient, and have created more diversified communication forms. Conclusion: Therefore, teachers should fully utilize the unique advantages of We-media in literary education to strengthen the communication and exchange between teachers and students and among the students themselves in the face of specific moral issues, and to cultivate the students’ ability to appropriately grasp moral phenomena and apply moral rules.

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