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You-Ping Wang,Chao-Hong Ma,Ru-Hai Li 한국차학회 2015 한국차학회지 Vol.- No.S
Arthropod insects are important pests that feed on leaves and young shoots often causing 10 to 20% loss in tea yield. Evaluation of the effect of major cultural practice such as pruning on the ecological aspect of the arthropod insects and their natural enemies is essential to develop a sound IPM program for organic tea plantation. The impac of summer pruning in mid-May on the arthropod communities was investigated with 3 different pruning intensities,i.e. light, heavy, and no pruning, in Hubei organic tea plantation. Light summer pruning had significant impact on the species and number of tea bush insect pests and their natural enemies within 1 month after pruning, and it lasted by2 months. Heavy pruning had greater impacts. Light pruning postponed the first peak in occurrence of Empoasca vitis (Gothe) for 20 days and the peak of Acaphylla theae Watt for 30 days. Heavy pruning postponed the first peak of Empoasca vitis (Gothe) for 25 days, and completely avoided the damage on tea bush from Acaphylla theae Watt. difference in diversity indices and the ratio of ‘natural enemies/insect pests’ of the arthropod communities on tea bushes by 3 and 4 months after pruning, respectively. The results suggest that light pruning can be used to control insect pests in organic tea plantations with the effect lasting for two months. Heavy pruning had a better control of insect pests than light pruning, but it is hardly to recommend without confirming the balance among sustainability of tea bush vigor in growth and tea yield in the following year, population of natural enemies and the efficacy of insect pest control. The optimum intensity of pruning may differ by individual tea plantation as the age and vigor of tea bush, soil fertility and management of tea bush nutrition differ by each tea plantation.
Wang, Hong-Ping,Zhang, You-Bo,Yang, Xiu-Wei,Zhao, Da-Qing,Wang, Ying-Ping The Korean Society of Ginseng 2016 Journal of Ginseng Research Vol.40 No.4
Background: Ginsenosides are the characteristic and principal components which manifest a variety of the biological and pharmacological activities of the roots and rhizomes of Panax ginseng (GRR). This study was carried out to qualitatively and quantitatively determine the ginsenosides in the cultivated and forest GRR. Methods: A rapid and sensitive ultra-high-performance liquid chromatography coupled with diode-array detector and quadrupole/time of flight tandem mass spectrometry (UPLC-DAD-QTOF-MS/MS) was applied to the qualitative analysis of ginsenosides and a 4000 QTRAP triple quadrupole tandem mass spectrometer (HPLC-ESI-MS) was applied to quantitative analysis of 19 ginsenosides. Results: In the qualitative analysis, all ingredients were separated in 10 min. A total of 131 ginsenosides were detected in cultivated and forest GRR. The method for the quantitative determination was validated for linearity, precision, and limits of detection and quantification. 19 representative ginsenosides were quantitated. The total content of all 19 ginsenosides in the forest GRR were much higher than those in the cultivated GRR, and were increased with the growing ages. Conclusion: This newly developed analysis method could be applied to the quality assessment of GRR as well as the distinction between cultivated and forest GRR.
The Effect of Mn/Al Substitution on the Structural Stability and Magnetic Properties of Mn₃AlC
Xin-You Wang,Ping-Zhan Si,Hui-Dong Qian,Yang Yang,Hong-Liang Ge,Jihoon Park,Xin-Qing Wang,Chul-Jin Choi 한국자기학회 2019 Journal of Magnetics Vol.24 No.1
The structural stability and magnetic properties of Mn3+xAl1-xC antiperovskite with varied Mn/Al substitution were studied systematically. Single phase Mn3+xAl1-xC alloys with antiperovskite structure were obtained in samples with x = −1/4, 0, 1/4, 1/2. An additional Mn23C₆ phase was precipitated from Mn3+xAl1-xC antiperovskite for x = 3/4 while Mn23C₆ phase was formed as major phase for x = 1. The mutual substitution of Mn and Al atoms has substantial effect on the Curie temperature and the saturation magnetization of the Mn3+xAl1-xC alloys. In comparison with the as-cast alloys, the as-annealed Mn3+xAl1-xC alloys exhibit reduced Mn/Al substitutions after high temperature homogenization, which enhances the ordering of Mn and Al atoms in the lattices. The Curie temperature of the homogenized Mn3+xAl1-xC increases with increasing Mn substitution to Al. The Mn₃AlC alloy shows the highest saturation magnetization among all samples with varied Mn/Al ratios. Most samples show zero coercivity and zero remanent magnetization. The maximum value of the magnetic entropy changes of Mn2.75Al1.25C at 285 K is 2.26 J/㎏ K in fields up to 3 T.
Genetic Diversity for Rice Blast Management
(You Yong Zhu),(Hai Ru Chen),(Yun Yue Wang),(Zuos Hea Li),(Yan Li),(Jing Hua Fan),(Jian Bing Chen),(Jin Xiang Fan),(Shi Sheng Yang),(Guang Liang Ma),(Ling Ping Hu),(Jin Yu Zou),(Christopher C . Mundt) 한국균학회 2001 Proceedings of the Fifth Korea-China Joint Symposi Vol.- No.-
Zhang, You-Gai,Shi, Jian-Xiang,Song, Chun-Hua,Wang, Peng,Dai, Li-Ping,Zhang, Jian-Ying,Shi, Jia-Chen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4
Meta-analyses have shown that microRNA polymorphisms have variable effects in different population. Yet, no meta-analysis investigated the association of two common polymorphisms of miRNA, mir-499 rs3746444 polymorphism and mir-149 rs2292832 polymorphism, with cancer risk in the Chinese population. We searched the PubMed, Web of Knowledge, MEDLINE, CNKI databases, as well as Cochrane library, updated on December 31, 2012 for assays regarding cancer risk association with these two common polymorphisms in the present meta-analysis. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were used to explore the strength of associations. The results showed that rs3746444 polymorphism was associated with increased cancer risk (dominant model: GG/AG vs. AA: OR = 1.43, 95% CI: 1.14-1.80; recessive model: GG vs. AG/AA: OR = 1.54, 95% CI: 1.04-2.30; homozygote model: GG vs. AA: OR = 1.69, 95% CI: 1.10-2.60; heterozygote model: AG vs. AA: OR = 1. 35, 95% CI: 1.09-1.67), and rs3746444 was associated with liver cancer in the subgroup of cancer types. For the rs2292832 polymorphism, the results showed no significant risk association in both overall pooled analysis and subgroup of cancer types, smoking status, gender and tea drinking status in the Chinese population. This meta-analysis suggested that the rs3746444 GG genotype is associated with increased cancer risk, especially liver cancer, while the rs2292832 polymorphism showed no association with cancer risk in Chinese.
Jian-Ping An,Xin Liu,Lai-Qing Song,Chun-Xiang You,Xiao-Fei Wang,Yu-Jin Hao 한국식물학회 2017 Journal of Plant Biology Vol.60 No.2
RING-finger-containing E3 ubiquitin ligases play important roles in plant response to biotic and abiotoc stresses. In this study, through homology analysis, a Malus× domestica MYB30-Interacting E3 Ligase 1 gene, MdMIEL1, was identified and subsequently cloned from apple ‘Gala’ (Malus×domestica). MdMIEL1 contained a zinc finger domain close to N-terminus and a RING finger domain close to Cterminus. Expression of MdMIEL1 was significantly induced by NaCl and H2O2 treatments. Further study demonstrated that the MdMIEL1-overexpressing Arabidopsis and apple calli were less tolerance to salt stress than wild-type control. In addition, transgenic plants had higher levels of reactive oxygen species (ROS) (H2O2 and O2 –). And transgenic Arabidopsis and apple calli exhibited more sensitive phenotype to H2O2 treatment, which was associated with increased levels of ROS. These findings indicate MdMIEL1 is an important regulator involved in plant response to salt and oxidative stresses tolerance.
He, Qiang,You, Hong,Li, Xin-Min,Liu, Tian-Hui,Wang, Ping,Wang, Bao-En Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4
The high mobility group box-1 (HMGB1) protein and NALP3 inflammasome have been identified to play important roles in inflammation and cancer pathogenesis, but the relationships between the two and cancer remain unclear. The current study investigated the relationship between HMGB1 and the NALP3 inflammasome in THP-1 macrophages. HMGB1 was found unable to activate the NALP3 inflammasome and failed to induce the release of the IL-$1{\beta}$ and IL-18 in THP-1 macrophages. HMGB1 was also found significantly enhanced the activity of ATP to induce IL-$1{\beta}$ and IL-18 by the induction of increased expression of pro-IL-$1{\beta}$ and pro-IL-18. This process was dependent on activation of RAGE, MAPK p38 and NF-${\kappa}B$ signaling pathway. These results demonstrate that HMGB1 promotes the synthesis of pro-IL-$1{\beta}$ and pro-IL-18 in THP-1 macrophages by the activation of p38 MAPK and NF-${\kappa}B$ through RAGE. HMGB1 likely plays an important role in the first step of the release of the IL-$1{\beta}$ and IL-18, preparing for other cytokines to induce excessive release of IL-$1{\beta}$ and IL-18 which promote inflammation and cancer progression.
Ying Yang,Dong Wang,Lei Cui,Hong-Hao Ma,Li Zhang,Hong-Yun Lian,Qing Zhang,Xiao-Xi Zhao,Li-Ping Zhang,Yun-Ze Zhao,Na Li,Tian-You Wang,Zhi-Gang Li,Rui Zhang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1
Purpose We sought to investigate the effectiveness and safety of dabrafenib in children with BRAFV600E-mutated Langerhans cell histiocytosis (LCH). Materials and Methods A retrospective analysis was performed on 20 children with BRAFV600E-mutated LCH who were treated with dabrafenib. Results The median age at which the patients started taking dabrafenib was 2.3 years old (range, 0.6 to 6.5 years). The ratio of boys to girls was 2.3:1. The median follow-up time was 30.8 months (range, 18.9 to 43.6 months). There were 14 patients (70%) in the risk organ (RO)+ group and six patients (30%) in the RO– group. All patients were initially treated with traditional chemotherapy and then shifted to targeted therapy due to poor control of LCH or intolerance to chemotherapy. The overall objective response rate and the overall disease control rate were 65% and 75%, respectively. During treatment, circulating levels of cell-free BRAFV600E (cfBRAFV600E) became negative in 60% of the patients within a median period of 3.0 months (range, 1.0 to 9.0 months). Grade 2 or 3 adverse effects occurred in five patients. Conclusion Some children with BRAFV600E-mutated LCH may benefit from monotherapy with dabrafenib, especially high-risk patients with concomitant hemophagocytic lymphohistiocytosis and intolerance to chemotherapy. The safety of dabrafenib is notable. A prospective study with a larger sample size is required to determine the optimal dosage and treatment duration.