RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
        • 등재정보
        • 학술지명
        • 주제분류
        • 발행연도
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        Circular RNA ROCK1, a novel circRNA, suppresses osteosarcoma proliferation and migration via altering the miR-532-5p/PTEN axis

        Liu Yize,Qiu Guanzhen,Luo Yinzhou,Li Shanshan,Xu Yeqiu,Zhang Yuanzhuang,Hu Jiayuan,Li Peifeng,Pan Hai,Wang Yong 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        As the most prevalent bone tumor in children and adolescents, the pathogenesis and metastasis of osteosarcoma (OS) remain largely unclear. Here, we investigated the expression and function of a novel circular RNA (circRNA), circROCK1-E3/E4, which is back-spliced from exons 3 and 4 of Rho-associated coiled-coil containing protein kinase 1 (ROCK1) in OS. We found that circROCK1-E3/E4, regulated by the well-known RNA-binding protein quaking (QKI), was downregulated in OS and correlated with unfavorable clinical features of patients with OS. Functional proliferation and cell motility assays indicated that circROCK1-E3/E4 serves as a tumor suppressor in OS cells. Mechanistically, circROCK1-E3/E4 suppressed proliferation and migration by upregulating phosphatase and tensin homolog (PTEN) through microRNA-532-5p (miR-532-5p) sponging. In the constructed nude mouse model, circROCK1-E3/E4 inhibited tumor growth and lung metastasis in vivo. This study demonstrates the functions and molecular mechanisms of circROCK1-E3/E4 in the progression of OS. These findings may identify novel targets for the molecular therapy of OS.

      • KCI등재

        Research progress of single-atom coating and its application prospect in protective coatings

        Chijia Wang,Qianqian Yin,Shuyi Liu,Jianxin Wang,Weihao Fan,Zhanjian Liu,Fatang Liu,Yize Liu,Huaiyuan Wang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.128 No.-

        Coating technology is the most economical and efficient approach to retard metal corrosion, and newcomposite coatings prepared by adding monoatomic fillers to a polymer matrix have excellent corrosionresistance and good mechanical properties. The single-atom coating formed by the immobilization ofmetal atoms alone on the matrix or filler represents the maximum utilization of atoms at the presentstage, which has unique coordination properties, active sites, and synergistic effects with the support. Compared with traditional fillers, single-atom fillers not only have the advantages of supporting fillersbut can also provide monatomic metals to form passivation films, promote the progress of catalytic passivationreactions, and combine organic compounds to generate new composite materials. This paperfocuses on the preparation methods and mechanisms of single-atom coatings in the field of batteriesand catalysts as well as the application of composite materials prepared by combining single-atom materialswith polymer matrices in the field of metal protection. The preparation methods, application prospects,and coating characteristics of various single-atom composites were summarized. In addition,we discuss the potential applications of single-atom coatings in the design of future composite coatings.

      • KCI등재

        Preparation of Copper-coated Mesophase Pitch-based Carbon Fibers by Electroless Plating Technique with the APTES Grafting Modification

        Jiangfan Shi,Yize Liu,Jianxiao Yang,Jun Li,Chong Ye,Dong Huang,Jinshui Liu,Xuanke Li 한국섬유공학회 2020 Fibers and polymers Vol.21 No.8

        An upgrade synthesis method of electroless copper plating was developed to prepare the copper-coated mesophasepitch-based carbon fibers (Cu@CF) with APTES (3-Aminopropyl triethoxysilane) grafting modification. The microstructureand properties of the fibers which were prepared by the APTES sensitization method were investigated and compared withthose prepared by the conventional SnCl2 sensitization method. The results showed that as-coated fibers sensitized by APTESdemonstrated to have better interfacial cohesion between the copper layer and the fiber surface than those sensitized by SnCl2did. Moreover, the resistivity of Cu@CF-APTES declined to 2.3±0.9 μΩ·cm, while that of Cu@CF-SnCl2 was 9.3±3.7μΩ·cm. Besides, not only the strength of Cu@CF-APTES increased, but the strength discreteness of them reduced due to thefact that no peeling phenomenon was observed between the copper layer and fiber during the stretch test.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼