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- 검색키워드
- 저자 : Yeseul Choi (검색결과 94 건)
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Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling
Choi Seong Ji,Kim Yeseul,Jeon Jehyun,Gwak Ho-Jin,Kim Mimi,Kang Kyojin,Kim Yohan,Jeong Jaemin,Jung Yun Kyung,Lee Kyeong Geun,Choi Ho Soon,Jung Dong-Hwan,Lee Sung-Gyu,Lee Yangsoon,Shin Su-Jin,Jang Kiseo 대한의학회 2021 Journal of Korean medical science Vol.36 No.28
Background: Cholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been investigated fully. We aimed to analyze the bile microbiome in normal conditions, chronic cholecystitis, and gallbladder cancer, and to identify candidate bacteria that play an important role in gallbladder carcinogenesis. Methods: We performed metagenome sequencing on bile samples of 10 healthy individuals, 10 patients with chronic cholecystitis, and 5 patients with gallbladder cancer, and compared the clinical, radiological, and pathological characteristics of the participants. Results: No significant bacterial signal was identified in the normal bile. The predominant dysbiotic bacteria in both chronic cholecystitis and gallbladder cancer were those belonging to the Enterobacteriaceae family. Klebsiella increased significantly in the order of normal, chronic cholecystitis, and gallbladder cancer. Patients with chronic cholecystitis and dysbiotic microbiome patterns had larger gallstones and showed marked epithelial atypia, which are considered as precancerous conditions. Conclusion: We investigated the bile microbiome in normal, chronic cholecystitis, and gallbladder cancer. We suggest possible roles of Enterobacteriaceae, including Klebsiella, in gallbladder carcinogenesis. Our findings reveal a possible link between a dysbiotic bile microbiome and the development of chronic calculous cholecystitis and gallbladder cancer.
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Choi, Minsung,Sung, Yonmo,Won, Myungjun,Park, Yeseul,Kim, Minkuk,Choi, Gyungmin,Kim, Duckjool Elsevier 2017 Journal of industrial and engineering chemistry Vol.48 No.-
<P><B>Abstract</B></P> <P>Numerical analysis of lean-premixed flames is utilized to investigate the correlation between turbulence and combustion, fuel–air mixing, and NO<SUB>x</SUB> emission using three types of micro gas turbine combustors. Swirl flows generating vortex breakdown and flow recirculation contributing to mixing uniformity are improved by interaction of burners. Mixing plays an important role in flame dynamics and NO<SUB>x</SUB> emission by means of the unmixedness parameter. To discuss the correlation between flame characteristics and vorticity structures, progress variable <I>c</I> is introduced. The flame stability is enhanced by ring-shaped, large-scale vorticity structures, and air–fuel mixing is increased by momentum and kinetic energy.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We study a numerical analysis of a lean-premixed flames in a micro gas turbine combustor. </LI> <LI> The large eddy simulation model is adopted to predict unsteady turbulent motions of methane-air premixed flames. </LI> <LI> The effect of the interaction of the between burners has a larger impact on the mixing process. </LI> <LI> A lower local equivalence ratio of the between burners produces a lower temperature distribution, reducing thermal NO<SUB>x</SUB> formation. </LI> <LI> The flame stability is enhanced by ring-shaped large scale coherent vorticity structures. </LI> <LI> Air–fuel mixing is also increased by strong momentum and high kinetic energy with low NO<SUB>x</SUB> emission. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Discrete Hollow Carbon Spheres Derived from Pyrolytic Copolymer Microspheres for Li-S Batteries
Choi, Yeseul,Yoon, Naeun,Kim, Nahyeon,Oh, Changil,Park, Hyejeong,Lee, Jung Kyoo The Electrochemical Society 2019 Journal of the Electrochemical Society Vol.166 No.3
<P>Discrete hollow carbon spheres (HCSs) with a high surface-to-volume ratio and distinct conducting shell have attracted immense attention as electrode materials for batteries and supercapacitors. In this study, we developed a novel and scalable method to synthesize well-defined HCSs. The HCSs were prepared using a pyrolytic soft template of styrene/acrylic acid copolymer microspheres. Sulfur could be effectively confined inside the pores of the uniform-sized HCSs (average diameter = 320 nm, shell thickness = 40–50 nm) to produce a S/HCS-65-IM (S content = 65 wt%) Li-S cathode using a modified sulfur-loading method involving solution impregnation followed by melt-diffusion (IM). S/HCS-65-IM delivered much higher capacity and greater cycling stability over 200 cycles and showed much lower impedance build up than S/HCS-65-PM prepared via the conventional melt-diffusion of a physical mixture of sulfur powder and HCSs. The sulfur utilization of S/HCS-65-IM was further improved by more than 20% by suppressing its lithium-polysulfide shuttle effect using a carbon-coated separator (CCS). The S/HCS-65-IM cathode (with CCS) also exhibited excellent cycling stability (capacity retention of >81% after 200 cycles at 0.5 C) and high rate capability with a reduced interfacial charge transfer resistance, suggesting that S/HCS-65-IM (with CCS) is a promising cathode for Li-S batteries.</P>
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Analysis of the Factors and Treatment Status of the pressure ulcer severe patients
Yeseul choi,Soo Kyung Pack 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Aim(s): The purpose of this study is to identify general characteristics, mortality rates, average CCI, variables that affect pressure ulcer patients, and the treatment status of pressure ulcer patients using data from the Korean Health Insurance Review and Assessment Service (HIRA). . For the purpose of this study, we focused on the study period between 2017 and 2019. Method(s): This study is a descriptive study. pressure injuries (PIs) patients were defined according to the AHRQ classification of PIs that occurred during hospitalization. Inpatients with PI were defined using the diagnosis code grade 3 or higher pressure sores (AL892, AL893, AL894) according to the International Classification of Diseases-10th (ICD-10th) revision. Result(s): The bedsore group had higher mortality and mean CCI values every year than the non-bedsore group. The pressure sore group had a higher average age, longer hospitalization days, and higher treatment costs than the non-bed sore group. In terms of the total number of surgeries, wound closure including marginal resection was the most common with 20,592, with an average of 1.17 per person, up to a maximum of 40. Among the total 544,643 patients with pressure sores, 145,445 (26.7%) received the most inflammatory dressing. The probability of developing bedsores increased by 2.691 (95% CI: 2.666–2.66) times for patients admitted to the intensive care unit and 3.455 (95% CI: 3.392–3.520) times for patients admitted to the isolation room. 6.886 (95% CI: 6.538–7.252) fold with necrotizing fasciitis, 5.680 (95% CI: 5.631–5.730) with sepsis, 3.229 (95% CI: 3.139–3.322) fold with osteomyelitis, 3.229 (95% CI: 3.139–3.322) in the presence of cellulitis increased the risk of pressure sores. Conclusion(s): It was confirmed that the pressure ulcer patient group had a higher mortality rate and higher cost than the non-bedsore group. Since it has been confirmed that infection increases the risk of pressure sores, infection prevention should be as important as positional change to prevent bedsores.
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Choi, Minsung,Li, Xinzhuo,Kim, Kibeom,Park, Yeseul,Sung, Yonmo,Choi, Gyungmin Elsevier 2019 Applied thermal engineering Vol.157 No.-
<P><B>Abstract</B></P> <P>The influence of tube vortex structure on flow fields and combustion characteristics in swirl-stabilized methane-pulverized coal flames was investigated experimentally. The detailed flame structures, such as the inner recirculation zone (IRZ) and exhaust tube vortex (ETV), were observed via particle image velocimetry (PIV) using various swirl combinations. The appearance of the ETV structure in the swirl-stabilized flame was an attractive flame to reduce NO<SUB>x</SUB> emissions that was shown to be associated with the oxygen-deficient and fuel-rich atmosphere similar to the environment of the IRZ. The flow fields of the swirl-stabilized flame were divided into four regions (zone (1): IRZ region; zone (2): stagnation region; zones (3) and (4): transition regions). For the co-swirling coal flames with swirl conditions of <I>S</I> <SUB>co</SUB> = 0.9 and 1.3, relatively uniform patterns of the root-mean-square of the axial velocity fluctuation (<I>u</I>′<SUB>rms</SUB>) appeared between the IRZ and ETV, including zone (2). In addition, the ratio of the strain rate from the velocity gradient (SR) of zones (3) and (4) converged between 35% and 40% in the co-swirling flames with swirl conditions of <I>S</I> <SUB>co</SUB> = 0.9 and 1.3. These parameters were strongly correlated with the generation of the ETV flame. The effects of the swirl intensity and swirl arrangement on the flame stability and combustion characteristics were investigated with regard to the ETV flame.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Swirl-stabilized flames are investigated using optical non-intrusive measurements. </LI> <LI> Effects of various swirl combinations are studied with regard to exhaust tube vortex. </LI> <LI> Behaviors of inner recirculation zone and exhaust tube vortex are investigated. </LI> <LI> Flame stability and combustion characteristics of exhaust tube vortex are evaluated. </LI> </UL> </P>
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What Patient31 Tells Us : Linguistic Functions of Twitter Hashtag
Yeseul Choi,Sujung Min 한국언어과학회 2021 언어과학 Vol.28 No.2
The purpose of this study is 1) to examine the types of tweets including #patient31 and evaluative language use of the tweets within the framework of Systemic Functional Linguistics, Appraisal Framework, and Critical Discourse Analysis; and 2) to show how the shared evaluation for patient31 represents her negatively and even reinforces the fixed image of ‘a reckless, irresponsible super spreader of virus.’ 101 tweets including the hashtag ‘#patient31’ were scraped randomly. The findings revealed that the hashtag and its linguistic use served both ideational function and interpersonal function. Communicating their evaluation for patient31, users shared their opinions, emotions, and lastly, built solidarity, and even ambient affiliation. The mutual consent to the evaluation or meaning-making process is realized in the phrase ‘don’t be patient31.’ However, there was a voice warning that this kind of meaning-making became cyberbullying toward an infected person. This study found that it is worth analyzing the language of SNS to show its multifunction rather than just its informational role.
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Yeseul Choi,Sujung Min 팬코리아영어교육학회(구 영남영어교육학회) 2022 영어교육연구 Vol.34 No.1
The topic of critical literacy has seen little research on EFL reading classrooms doing Systemic Functional Linguistics (SFL) with students, especially in the high school context. Critical literacy can stimulate learners’ capabilities of thinking and plays an essential role in promoting learners’ linguistic capacity and reading ability. This study, therefore, examined how instructional use of SFL analytic resources enhanced critical literacy in high school English reading classes by analyzing one high school reading classroom in which students read online consumer reviews and a text of the political speech. The study explored how students responded to applying linguistic tools such as the appraisal and identification analysis that made discernible the practice in which discourse arranged people to think and behave in certain ways, not the others. Findings suggested that SFL analysis tools aided students in recognizing linguistic items that authors chose and bringing contextual resources to interpret and evaluate the discourse, and finally supporting their ability in critical reading. This study offers meaningful and practical data for both researchers and educators in developing a curriculum for a critical reading class using SFL.
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미분탄 스월버너에서 석탄/바이오매스 혼소시 바이오매스 입자 크기가 화염구조 및 연소특성에 미치는 영향
박예슬(Yeseul Park),최민성(Minsung Choi),리신줘(Xinzhuo Li),정찬호(Chanho Jeong),이지훈(Lee Jihoon),최경민(Gyungmin Choi) 한국연소학회 2020 한국연소학회지 Vol.25 No.4
The flame structure and combustion characteristics of co-firing coal and LPG with different sizes of biomass were investigated in a dual swirl pulverized coal burner by using a high-speed camera with bandpass filter and PIV system. Three sizes of spent mushroom compost (<45, 45~90, 90~150 ㎛) were cofired with pulverized coal (45~90 ㎛) at a blending ratio of 20%. When the biomass of the same size with coal was used, the turbulence intensity had the highest uniformity while other cases exhibited locally strong turbulent intensity. The combustion using <45 ㎛ biomass was terminated early compared to other conditions, whereas the reaction region was the widest for 45~90 ㎛ biomass. The flame had uniform turbulent intensity with wide and strong reaction when the biomass size was equal to that of coal. When using 45~90 ㎛ of biomass, high velocity was maintained in the overall region and CH<SUP>*</SUP> radical was observed in a wide region with the highest radical intensity.
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