Discrepancy between Clinician-rated and Self-reported Depression Severity is Associated with Adverse Childhood Experience, Autistic-like Traits, and Coping Styles in Mood Disorders

Risa Yamada(Risa Yamada ),Takeshi Fujii(Takeshi Fujii ),Kotaro Hattori(Kotaro Hattori ),Hiroaki Hori(Hiroaki Hori ),Ryo Matsumura(Ryo Matsumura ),Tomoko Kurashimo(Tomoko Kurashimo ),Naoko Ishihara(Nao 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.2

Objective: This study aimed to determine if the discrepancy between depression severity rated by clinicians and that reported by patients depends on key behavioral/psychological features in patients with mood disorders. Methods: Participants included 100 patients with mood disorders. First, we examined correlations and regressions between scores on the Hamilton Depression Rating Scale (HAMD) and Beck Depression Inventory (BDI). Second, we divided the participants into those who provided 1) greater ratings for the BDI compared with the HAMD (BDI relative- overrating, BO) group, 2) comparable ratings for the BDI and HAMD (BDI relatively concordant, BC) group, or 3) less ratings for the BDI (BDI relative-underrating, BU) group. Adverse childhood experiences, autistic-like traits, and coping styles were evaluated with a six-item short version of the Childhood Trauma Questionnaire (CTQ-6), the Social Responsiveness Scale for Adults (SRS-A), and the Ways of Coping Checklist (WCCL), respectively. Results: A significant correlation was found between HAMD and BDI scores. Total and emotional abuse subscale scores from the CTQ-6, and the self-blame subscale scores from the WCCL were significantly higher for the BO group compared with the BU group. The BO group also elicited significantly higher SRS-A total scores than did the other groups. Conclusion: These findings suggest that patients with adverse emotional experiences, autistic-like traits, and self-blame coping styles perceive greater distress than that evaluated objectively by clinicians. The results indicate the need for inclusion of subjective assessments to effectively evaluate depressive symptoms in patients deemed to have these psycho- behavioral concerns.

New Development of Tailor-made Peptide Vaccine for Cancer Immunotherapy

Akira, Yamada,Hideaki, Yamada,Kyogo, Itoch 가톨릭 의과학연구원 2003 가톨릭 의과학연구원 국제학술대회 Vol.7 No.-

Electrical Properties of Planar-type Magnetic Tunnel Junction Covered with Insulating Layer

Shogo Yamada,Tsutomu Yamada,Jun-ichi Shirakashi,Yasushi Takemura 한국자기학회 2007 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Evaluation of 131I (monoiodide) BSP for Clinical Studies

Ueda, Hideo,Iro, Masahiro,Kurata, Kunio,Yamada, Hideo,Iwase, Tohru,Migita, Tohru,Kameda, Haruo,Kato, Sadatake,Sato, Noboru,Ide, Kazuko,Wakebayashi, Takao 대한핵의학회 1971 핵의학 분자영상 Vol.5 No.1

"In 1925 Rosenthal and White introduced a bromosulfophthalein (BSP) dye retention test as a sensitive indicator of liver function. Even now it is regared as one of the most sensitive agents for the detection of non-icteric liver disease (liver cirrhosis, early stage of acute-hepatitis and hepatic tumor). BSP accumulates in the liver cells, conjugates with glutathione and is excreted into the bile. Therefore, a disorder in its excretion is due to a disturbance of one of these processes. Since bilirubin and BSP compete for uptake by the liver and increased serum bilirubin interferes with the colorimetric determination of BSP, it has been considered that BSP test is inappropriate for the differential diagnosis of jaundice conditions. It has been generally said that when jaundice is present, the BSP test is useless and should not be performed. In 1955, Taplin et al. labeled rose bengal, a dye similarly metabolized in the liver as BSP, with 131I and measured the hepatic excretion of this dye by external monitoring. Laster, Blahd et al. applied this method to the determination of the peripheral pool, succeeding in the diagnosis of chronic and subacute hepatic diseases without colorimetry. In 1968, Yamada, Taplin et al. suggested the possibility of differentiating so-called medical jaundice from surgical jaundice by scanning the subjects during 24 to 48 hours following intravenous injection of 131I-labeled rose bengal. As mentioned before, many authorities hold the opinion that BSP is not proper for the differential diagnosis of jaundice states. Some have tried to diagnose biliary tract obstruction by a malignant tumor by measuring BSP excretion into duodenal fluid and others by quantitating changes in serum levels of conjugated and free BSP. Furthermore, Burton et al. reported that in patients with extrahepatic obstructive jaundice, BSP retention was observed for 24 days after its administration. From a consideration of all these finding we came to a conclusion that the differential diagnosis of various jaundice states, (medical, surgical and constitutional) is possible by sequential scanning with radioisotope-labeled BSP, as with rose bengal, in accordance with procedures described by Yamada, Taplin et al. The evidence suggested that labeled BSP might make a more important contribution than rose bengal. "

A method of selecting an active factor and its robustness against correlation in the data

Yamada, Shu,Harashima, Jun The Korean Society for Quality Management 2003 The Asian Journal on Quality Vol.4 No.2

A reducing variation of quality characteristics is a typical example of quality improvement. In such a case, we treat the quality characteristic, as a response variable and need to find active factors affecting the response from many candidate factors since reducing the variation of the response will be achieved by reducing variation of the active factors. In this paper, we first derive a method of selecting an active factor by linear regression. It is well known that correlation between factors deteriorates the precision of estimators. We, therefore, examine robustness of the selecting method against the correlation in the data set and derive an evaluation method of the deterioration brought by the correlation. Furthermore, some examples of selecting and evaluation methods are shown to demonstrate practical usage of the methods.

Recent Research on Spatial Structures

Yamada, Motohiko Korean Association for Spatial Structures 2002 한국공간구조학회지 Vol.2 No.2

Finite element procedure of initial shape determination for hyperelasticity

Yamada, Takahiro Techno-Press 1998 Structural Engineering and Mechanics, An Int'l Jou Vol.6 No.2

In the shape design of flexible structures, it is useful to predict the initial shape from the desirable large deformed shapes under some loading conditions. In this paper, we present a numerical procedure of an initial shape determination problem for hyperelastic materials which enables us to calculate an initial shape corresponding to the prescribed deformed shape and boundary condition. The present procedure is based on an Arbitrary Lagrangian-Eulerian (ALE) finite element method for hyperelasticity, in which arbitrary change of shapes in both the initial and deformed states can be treated by considering the variation of geometric mappings in the equilibrium equation. Then the determination problem of the initial shape can be formulated as a nonlinear problem to solve the unknown initial shape for the specified deformed shape that satisfies the equilibrium equation. The present approach can be implemented easily to the finite element method by employing the isoparametric hypothesis. Some basic numerical results are also given to characterize the present procedure.

Photocatalytic hydrogen evolution from carbon-neutral oxalate with 2-phenyl-4-(1-naphthyl)quinolinium ion and metal nanoparticles

Yamada, Yusuke,Miyahigashi, Takamitsu,Ohkubo, Kei,Fukuzumi, Shunichi The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.30

<P>Photocatalytic hydrogen evolution has been made possible by using oxalate as a carbon-neutral electron source, metal nanoparticles as hydrogen-evolution catalysts and the 2-phenyl-4-(1-naphthyl)quinolinium ion (QuPh<SUP>+</SUP>–NA), which forms the long-lived electron-transfer state upon photoexcitation, as a photocatalyst. The hydrogen evolution was conducted in a deaerated mixed solution of an aqueous buffer and acetonitrile (MeCN) [1 : 1 (v/v)] by photoirradiation (<I>λ</I> > 340 nm). The gas evolved during the photocatalytic reaction contained H<SUB>2</SUB> and CO<SUB>2</SUB> in a molar ratio of 1 : 2, indicating that oxalate acts as a two-electron donor. The hydrogen yield based on the amount of oxalate reached more than 80% under pH conditions higher than 6. Ni and Ru nanoparticles as well as Pt nanoparticles act as efficient hydrogen-evolution catalysts in the photocatalytic hydrogen evolution. The photocatalyst for hydrogen evolution can be used several times without significant deactivation of the catalytic activity. Nanosecond laser flash photolysis measurements have revealed that electron transfer from oxalate to the photogenerated QuPh&z.rad;–NA&z.rad;<SUP>+</SUP>, which forms a π-dimer radical cation with QuPh<SUP>+</SUP>−NA [(QuPh&z.rad;–NA&z.rad;<SUP>+</SUP>)(QuPh<SUP>+</SUP>–NA)], occurs followed by subsequent electron transfer from QuPh&z.rad;–NA to the hydrogen-evolution catalyst in the photocatalytic hydrogen evolution. Oxalate acts as an efficient electron source under a wide range of reaction conditions.</P> <P>Graphic Abstract</P><P>Photocatalytic hydrogen evolution using a carbon-neutral electron donor with metal nanoparticles. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp41906h'> </P>

日本の國境問題

Yamada Yoshihiko(山田吉彦) 한국국제정치학회 2008 한국국제정치학회 학술대회 발표논문집 Vol.- No.-

Recent topics on gastrointestinal allergic disorders

Yamada Yoshiyuki 대한소아청소년과학회 2023 Clinical and Experimental Pediatrics (CEP) Vol.66 No.6

Gastrointestinal (GI) allergies are broadly associated with food allergies and divided into groups based on the degree of allergen-specific immunoglobulin E (IgE) involvement: IgE-mediated, non-IgE-mediated, and mixed. Non-IgE-mediated GI food allergies are mostly observed in neonates and infants and include food protein-induced enterocolitis syndrome (FPIES), food protein-induced allergic proctocolitis (FPIAP), and food protein-induced enteropathy (FPE). In addition to the classical phenotype, unique phenotypes such as vomiting and bloody stool, suspected sepsis, and overlapping eosinophilic GI disorders (EGIDs) have increased in Japan over the past 2 decades. Some of these cases were defined as having chronic FPIES. More recently, cases of hen’s-egg FPIES in Japan have increased dramatically since 2018, albeit for unknown reasons. Typical mixed-type food allergies are EGIDs, characterized by prominent eosinophil infiltration in the GI tract leading to GI symptoms. EGIDs are broadly classified into eosinophilic esophagitis (EoE) and non-EoE EGIDs that involve the GI tract with the exception of the esophagus. Of the EGIDs, EoE is the best known, as the number of cases has increased dramatically in Western countries, whereas pediatric EoE remains rare in Asia and non-EoE EGIDs may be more prevalent in Japan. A recent Japanese national survey showed that pediatric non-EoE EGIDs were persistent and severe compared to those in adults, possibly requiring further effective therapeutic options. Among the EGIDs, FPIAP is pathologically diagnosed as an infantile form of eosinophilic colitis. In addition, recent FPIES and FPE cases also involved eosinophilic inflammation. Recent cases of GI allergies may be associated with type 2 inflammation. A better understanding of the interactions between GI allergies and type 2 inflammation may clarify the pathogenesis of the recent increase in GI allergies.