지각된 가치가 온라인 구매후기 작성동기와 구전행동 속도에 미치는 영향에 관한 탐색적 연구

왕맹맹(Meng-Meng Wang),초수봉(Shu-Feng (Simon) Xiao),민대환(Dai-Hwan Min) 한국무역연구원 2020 무역연구 Vol.16 No.2

Purpose–The importance of online word of mouth has generated considerable interest among both academics and practitioners. The present study aims to introduce a framework that addresses the factors influencing quick online word of mouth. Specifically, this paper examines the impacts of various motivations of online reviews, which are shaped by different consumer values, on quick online word of mouth. Design/methodology/approach–This study collected survey data from 328 consumers in China and tested the research model using a structural equation approach. Findings - Our results suggest that online review motivations significantly influence the quick online word of mouth among Chinese consumers, which are shaped by consumer values. We conclude that in order to better understand online word of mouth of consumers in the world’s largest emerging market, it might be more beneficial for managers to concentrate on analyzing various motivations that incentivize online consumers to write reviews and the respective consumer values shaping such review motivations. Research implications or Originality–Based on results from a survey sent to online consumers in China, we develop implications for online word of mouth management and research as well as practitioners. One of the most notable contributions of this study is to demonstrate that online review motivations, which are shaped by consumer values, have important impacts on quick online word of mouth. However, different types of online review motivations, which are shaped by different consumer values, exert different effects on quick online word of mouth, suggesting that not all consumer values and online review motivations have the equal effect on quick online word of mouth. We enhance understanding of what drive consumers’ quick online word of mouth, and how consumer values and reviews motivations matter.

Proteomic Analysis of Erythritol-Producing Yarrowia lipolytica from Glycerol in Response to Osmotic Pressure(s)

( Li Bo Yang ),( Xiao Meng Dai ),( Zhi Yong Zheng ),( Li Zhu ),( Xiao Bei Zhan ),( Chi Chung Lin ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7

Osmotic pressure is a critical factor for erythritol production with osmophilic yeast. Protein expression patterns of an erythritol-producing yeast, Yarrowia lipolytica, were analyzed toidentify differentially-expressed proteins in response to osmotic pressure. In order to analyze intracellular protein levels quantitatively, two-dimensional gel electrophoresis was performed to separate and visualize the differential expression of the intracellular proteins extracted from Y. lipolytica cultured under low (3.17 osmol/kg) and high (4.21 osmol/kg) osmotic pressures. Proteomic analyses allowed identification of 54 differentially-expressed proteins among the proteins distributed in the range of pI 3-10 and 14.4-97.4 kDa molecular mass between the osmotic stress conditions. Remarkably, the main proteins were involved in the pathway of energy, metabolism, cell rescue, and stress response. The expression of such enzymes related to protein and nucleotide biosynthesis was inhibited drastically, reflecting the growth arrest of Y. lipolytica under hyperosmotic stress. The improvement of erythritol production under highosmotic stress was due to the significant induction of a range of crucial enzymes related to polyols biosynthesis, such as transketolase and triosephosphate isomerase, and the osmotic stress responsive proteins like pyridoxine-4-dehydrogenase and the AKRs family. The polyols biosynthesis was really related to an osmotic response and a protection mechanism against hyperosmotic stress in Y. lipolytica. Additionally, the high osmotic stress could also induce other cell stress responses as with heat shock and oxidation stress responses, and these responsive proteins, such as the HSPs family, catalase T, and superoxide dismutase, also had drastically increased expression levels under hyperosmotic pressure.

Concurrent Hypermethylation of SFRP2 and DKK2 Activates the Wnt/β-Catenin Pathway and Is Associated with Poor Prognosis in Patients with Gastric Cancer

Wang, Hao,Duan, Xiang-Long,Qi, Xiao-Li,Meng, Lei,Xu, Yi-Song,Wu, Tong,Dai, Peng-Gao Korean Society for Molecular and Cellular Biology 2017 Molecules and cells Vol.40 No.1

Aberrant hypermethylation of Wnt antagonists has been observed in gastric cancer. A number of studies have focused on the hypermethylation of a single Wnt antagonist and its role in regulating the activation of signaling. However, how the Wnt antagonists interacted to regulate the signaling pathway has not been reported. In the present study, we systematically investigated the methylation of some Wnt antagonist genes (SFRP2, SFRP4, SFRP5, DKK1, DKK2, and APC) and their regulatory role in carcinogenesis. We found that aberrant promoter methylation of SFRP2, SFRP4, DKK1, and DKK2 was significantly increased in gastric cancer. Moreover, concurrent hypermethylation of SFRP2 and DKK2 was observed in gastric cancer and this was significantly associated with increased expression of ${\beta}-catenin$, indicating that the joint inactivation of these two genes promoted the activation of the Wnt signaling pathway. Further analysis using a multivariate Cox proportional hazards model showed that DKK2 methylation was an independent prognostic factor for poor overall survival, and the predictive value was markedly enhanced when the combined methylation status of SFRP2 and DKK2 was considered. In addition, the methylation level of SFRP4 and DKK2 was correlated with the patient's age and tumor differentiation, respectively. In conclusion, epigenetic silencing of Wnt antagonists was associated with gastric carcinogenesis, and concurrent hypermethylation of SFRP2 and DKK2 could be a potential marker for a prognosis of poor overall survival.

Concurrent Hypermethylation of SFRP2 and DKK2 Activates the Wnt/β-Catenin Pathway and Is Associated with Poor Prognosis in Patients with Gastric Cancer

Hao Wang,Xiang-Long Duan,Xiao-Li Qi,Lei Meng,Yi-Song Xu,Tong Wu,Peng-Gao Dai 한국분자세포생물학회 2017 Molecules and cells Vol.40 No.1

Aberrant hypermethylation of Wnt antagonists has been observed in gastric cancer. A number of studies have focused on the hypermethylation of a single Wnt antagonist and its role in regulating the activation of signaling. However, how the Wnt antagonists interacted to regulate the signaling pathway has not been reported. In the present study, we systematically investigated the methylation of some Wnt antagonist genes (SFRP2, SFRP4, SFRP5, DKK1, DKK2, and APC) and their regulatory role in carcinogenesis. We found that aberrant promoter methylation of SFRP2, SFRP4, DKK1, and DKK2 was significantly increased in gastric cancer. Moreover, concurrent hypermethylation of SFRP2 and DKK2 was observed in gastric cancer and this was significantly associated with increased expression of -catenin, indicating that the joint inactivation of these two genes promoted the activation of the Wnt signaling pathway. Further analysis using a multivariate Cox proportional hazards model showed that DKK2 methylation was an independent prognostic factor for poor overall survival, and the predictive value was markedly enhanced when the combined methylation status of SFRP2 and DKK2 was con-sidered. In addition, the methylation level of SFRP4 and DKK2 was correlated with the patient’s age and tumor differentiation, respectively. In conclusion, epigenetic silencing of Wnt antagonists was associated with gastric carcinogenesis, and concurrent hypermethylation of SFRP2 and DKK2 could be a potential marker for a prognosis of poor overall survival.

Tug of War-Who is the Winner? Canker Disease Restructures the Endophytic Bacterial Community of Citrus

Jian-Yu Zhou,Yi Zhang,Wen-Ping Xu,Misbah Naz,Xiao-Meng Li,Xu Li,Bi-Ying Zhao,Shan-Shan Qi,Zhi-Cong Dai,Dao-Lin Du 한국원예학회 2023 원예과학기술지 Vol.41 No.5

Chinese patent herbal medicine (Shufeng Jiedu capsule) for acute upper respiratory tract infections: A systematic review and meta-analysis

Ying-ying Zhang,Ru-yu Xia,Shi-bing Liang,Xiao-yang Hu,Meng-yuan Dai,Yi-lin Li,Le-yi Zhao,Michael Moore,Yu-tong Fei,Jian-ping Liu 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.3

Background: Shufeng Jiedu capsule has been widely used in China for acute upper respiratory tract infections (AURTIs). The aim of this study was to evaluate its effectiveness and safety for AURTIs. Methods: Randomized controlled trials comparing SFJD with conventional drug for patients with AURTIs were included. Eight databases were searched from their inceptions to February 2021. Data was synthesized using risk ration (RR) or mean difference (MD) with their 95% confidence interval (CI). The primary outcome was resolution time of typical symptoms. Results: Twenty-five RCTs involving 3410 patients were included. SFJD in combination with conventional drug was associated with; in common cold shortening the duration of fever (MD −1.54 days, 95% CI [−2.15,−0.92], I2 = 80%, n = 385, 3 trials) and cough (MD −1.22 days, 95% CI [−1.52, −0.93]); in herpangina, shortening the duration of fever (MD -0.68 days, 95% CI [−1.15, −0.21], I2 = 68%, n = 140, 2 trials) and blistering (MD −0.99 days, 95% CI [−1.23, −0.76], n = 386, 3 trials); in acute tonsillitis and acute pharyngitis shortening the duration of fever (MD −1.13 days, 95% CI [−1.36, −0.90], I2 = 33%, n = 688, 7 trials) and sore throat (MD −1.13 days, 95% CI [−1.40, −0.86], I2 = 84.1%, n = 1194, 10 trials). SFJD also improving their cure rate with a range (1–5 days). No serious adverse events were reported. Conclusion: Low certainty evidence suggests that SFJD appears to shorten the duration of symptoms in AURTIs, improve cure rate and seems safe for application. However, high quality placebo controlled trials are warranted to confirm its benefit.

Analytical and Numerical Studies on Steel Columns with Novel Connections in Modular Construction

En-Feng Deng,Jia-Bao Yan,Yang Ding,Liang Zong,Zhong-Xian Li,Xiao-Meng Dai 한국강구조학회 2017 International Journal of Steel Structures Vol.17 No.4

modular construction is a new type of promising structures. This type of structure is an excellent alternative to conventional on-site buildings with advantages of shortened construction time, improved construction quality and reduced environmental pollution. A new concept of modular construction with novel connections has been proposed. This paper mainly focuses on the behavior and design of the innovative steel column working together with tenons at both ends. The fourthdifferential equation was firstly adopted to develop a theoretical model to determine the buckling length of the column. Then, a 3-D nonlinear finite element (FE) model was developed to simulate the ultimate strength behavior of the novel column under pure compression. Parametric studies reveal that the tenons play a significant role in affecting the ultimate load and the corresponding end shortening, among which the length of the tenons is the most important factor. The design approach and recommendations are also discussed through assessing the applicability of the current design code.