http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Jeong-Won Lee,Sang-Koog Kim,Jonggeol Kim,Jong-Ryul Jeong,Jae-Seok Ahn,Sung-Chul Shin 한국자기학회 2001 Journal of Magnetics Vol.6 No.2
We have developed a three-axis configurational in situ SMOKE apparatus by which three-dimensional vector magnetization reversal processes are studied for ultrathin Co films grown on a Pd (111) single crystal in the thickness range of spin reorientation transition. This study provides a better understanding of magnetization reversal motions with the knowledge of three components of the magnetization vector at the transition of an easy axis of magnetization from the film normal at 5 ML Co to in-plane at 6 ML Co (ML denotes monolayer). For a 5.25 ML Co, it was observed that a slightly canted magnetization vector from the film normal rotated in the film plane under an applied field direction parallel to the film normal.
mRNA expression and metabolic regulation of <i>npy</i> and <i>agrp1/2</i> in the zebrafish brain
Jeong, Inyoung,Kim, Eunmi,Kim, Suhyun,Kim, Hwan-Ki,Lee, Dong-Won,Seong, Jae Young,Park, Hae-Chul Elsevier 2018 Neuroscience Letters Vol.668 No.-
<P><B>Abstract</B></P> <P>Neuropeptide Y (NPY) is an evolutionarily conserved neuropeptide implicated in feeding regulation in vertebrates. In mammals, NPY neurons coexpress Agouti-related protein (AgRP) in the arcuate nucleus of the hypothalamus, and NPY/AgRP neurons activate orexigenic signaling to increase food intake. Zebrafish express <I>npy</I> and two <I>agrp</I> genes, <I>agrp1</I> and <I>agrp2</I>, in the brain. Similar to mammals, NPY and AgRP1 act as orexigenic factors in zebrafish, but the exact distribution of NPY and AgRP neurons in the zebrafish brain and the regulation of these genes by metabolic states remain unclear. In this study, we analyzed the tissue distribution of <I>npy, agrp1</I>, and <I>agrp2</I> mRNA in the brain of larval and adult zebrafish. We detected the expression of <I>agrp1</I>, but not <I>npy</I>, in the hypothalamus of larval zebrafish. In the adult zebrafish brain, <I>npy</I> mRNA expression was detected in the dorsal area of the periventricular and lateral hypothalamus, but fasting induced upregulation of <I>npy</I> only in the lateral hypothalamus, indicating that NPY neurons in this area are implicated in feeding regulation. However, consistent with the findings in larval zebrafish, NPY neurons in the hypothalamus did not coexpress AgRP1. In contrast, fasting resulted in a dramatic increase in AgRP1 neurons in the ventral periventricular hypothalamus, which do not coexpress NPY. In addition, we found for the first time that <I>npy</I>- and <I>agrp1</I>-expressing neurons function as GABAergic inhibitory neurons in zebrafish, as they do in mammals. Taken together, our results show that the zebrafish NPY/AgRP system is involved in appetite regulation. In addition, our data suggest that although <I>npy</I> and <I>agrp1</I> were initially expressed in distinct neurons, evolution has resulted in their coexpression in mammalian hypothalamic neurons.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We analyzed <I>npy, agrp1,</I> and <I>agrp2</I> mRNA distribution in larval/adult zebrafish brains. </LI> <LI> NPY and AGRP1 neurons function as GABAergic inhibitory neurons in larval zebrafish. </LI> <LI> <I>Npy</I> and <I>agrp1/2</I> are expressed in distinct neurons in the hypothalamus. </LI> <LI> Metabolic state regulated NPY neurons in the lateral hypothalamus of adult zebrafish. </LI> <LI> Metabolic state regulated AgRP1 neurons in the adult zebrafish ventral hypothalamus. </LI> </UL> </P>
Won, Jumin,Hong, Young Joon,Jeong, Myung Ho,Park, Hyuk Jin,Kim, Min Chul,Kim, Woo Jin,Kim, Hyun Kuk,Sim, Doo Sun,Kim, Ju Han,Ahn, Youngkeun,Cho, Jeong Gwan,Park, Jong Chun Chonnam National University Medical School 2016 CMJ Vol.52 No.2
<P>Statins and renin-angiotensin system (RAS) blockers are key drugs for treating patients with an acute myocardial infarction (AMI). This study was designed to show the association between treatment with statins or RAS blockers and clinical outcomes and the efficacy of two drug combination therapies in patients with ischemic heart failure (IHF) who underwent revascularization for an AMI. A total of 804 AMI patients with a left ventricular ejection fraction <40% who undertook percutaneous coronary interventions (PCI) were analyzed using the Korea Acute Myocardial Infarction Registry (KAMIR). They were divided into four groups according to the use of medications [Group I: combination of statin and RAS blocker (n=611), Group II: statin alone (n=112), Group III: RAS blocker alone (n=53), Group IV: neither treatment (n=28)]. The cumulative incidence of major adverse cardiac and cerebrovascular events (MACCEs) and independent predictors of MACCEs were investigated. Over a median follow-up study of nearly 1 year, MACCEs had occurred in 48 patients (7.9%) in Group I, 16 patients (14.3%) in Group II, 3 patients (5.7%) in Group III, 7 patients (21.4%) in Group IV (p=0.013). Groups using RAS blocker (Group I and III) showed better clinical outcomes compared with the other groups. By multivariate analysis, use of RAS blockers was the most powerful independent predictor of MACCEs in patients with IHF who underwent PCI (odds ratio 0.469, 95% confidence interval 0.285-0.772; p=0.003), but statin therapy was not found to be an independent predictor. The use of RAS blockers, but not statins, was associated with better clinical outcomes in patients with IHF who underwent PCI.</P>
Won Jun Jeong,Byung Jo Choi,Jeong Kye Hwang,Seung Mo Yuk,Min Jong Song,Sang Chul Lee 대한외과학회 2016 Annals of Surgical Treatment and Research(ASRT) Vol.90 No.2
Laparoscopic live donor nephrectomy (DN) has been established as a useful alternative to the traditional open methods of procuring kidneys. To maximize the advantages of the laparoendoscopic single-site (LESS) method, we applied natural orifice specimen extraction to LESS-DN. A 46-year-old woman with no previous abdominal surgery history volunteered to donate her left kidney to her husband and underwent single-port laparoscopic DN with transvaginal extraction. The procedure was completed without intraoperative complications. The kidney functioned well immediately after transplantation, and the donor and recipient were respectively discharged 2 days and 2 weeks postoperatively. Single-port laparoscopic DN and transvaginal graft extraction is feasible and safe.