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파력발전장치의 WECAN Level 1 통합성능해석 프로그램 개발
하윤진(Y.J Ha),박지용(J.Y Park),김경환(K.H Kim),박세완(S.W Park),김길원(K.W Kim),김정석(J.S Kim),이정희(J.H Lee),오재원(J.W Oh),노찬(R. Chan),최장영(J.Y Choi),장강현(G.H Jang),천호정(H.J Cheon),김재환(J.H Kim) 한국신재생에너지학회 2021 한국신재생에너지학회 학술대회논문집 Vol.2021 No.7
본 연구에서는 진동수주형과 가동물체형 파력발전장치에 대하여 통합성능해석을 위한 WECAN Level 1 프로그램 개발하였다. 본 프로그램은 파력발전장치 설계 시 그 설계된 파력발전장치의 연간발전량을 해석할 수 있는 프로그램이며, 각 에너지변환단계를 통합하여 해석할 수 있고 연간발전량을 수십초 내에 해석할 수 있는 프로그램이다. 본 프로그램과 유사한 프로그램으로는 NREL에서 개발한 WEC-Sim, DNV-GL에서 개발한 WaveDyn이라는 프로그램이 있으며, 이 중 WEC-Sim은 매트랩 코드 기반으로 공개되어 있고 범용적인 활용이 가능하도록 구성되어 있다. 다만 본 프로그램의 경우에는 2차 및 3차 에너지변환 단계에서 단순히 효율만을 고려하고 있으며 1차 에너지변환 단계의 경우 진동 수주형 파력발전장치를 제외한 가동물체형 파력발전장치만을 해석할 수 있도록 구성되어 있다. 따라서 WECAN Level 1 프로그램은 이러한 한계를 극복하고자 개발되었으며, 상대적으로 다양한 파력발전장치 종류를 해석할 수 있도록 확장하고자 하였다. 본 연구에서는 기존의 파력발전장치 통합성능해석 프로그램과 비교하여 자단점을 분석하고 향후 개발방향을 소개하고자 하며, 이를 통하여 국내 파력발전장치의 성능평가 및 설계기술을 고도화하고 파력발전장치의 상용화를 선도하고자 한다.
( Ada W. Y. Tse ),( Larry H. Lai ),( C. C. Lee ),( Kelvin K. F. Tsoi ),( Vincent W. S. Wong ),( Yawen Chan ),( Joseph J. Y. Sung ),( Francis K. L. Chan ),( Justin C. Y. Wu ) 대한소화기기능성질환·운동학회 2010 Journal of Neurogastroenterology and Motility (JNM Vol.16 No.1
Introduction: Psychiatric comorbidity is common in patients with functional dyspepsia (FD) but a good screening tool for psychiatric disorders in gastrointestinal clinical practice is Lacking. Aims: 1) Evaluate the performance and optimal cut-off of 12-item General Health Questionnaire (GHQ-12) as a screening tool for psychiatric disorders in FD patients; 2) Compare health-related quality of Life (HRQoL) in FD patients with and without psychiatric comorbidities. Methods: Consecutive patients fulfilling Rome III criteria for FD without medical co-morbidities and gastroesophageal reflux disease were recruited in a gastroenterology clinic. The followings were conducted at 4 weeks after index oesophagogastroduodenoscopy: self-administrated questionnaires on socio-demographics, dyspeptic symptom severity (4-point Likert scale), GHQ-12, and 36-item short-form health survey (SF-36). Psychiatric disorders were diagnosed with Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) by a trained psychiatrist, which served as reference standard. Results: 55 patients underwent psychiatrist-conducted interview and questionnaire assessment. 27 (49.1%) had current psychiatric disorders as determined by SCID (anxiety disorders: 38.2%, depressive disorders: 16.4%). Receiver operating characteristic curve analysis of GHQ-12 revealed an area under curve of 0.825 (95%CI: 0.698-0.914). Cut-off of GHQ-12 at 3 gave a sensitivity of 63.0% (95%CI = 42.4-80.6%) and specificity of 92.9% (95%CI = 76.5%-98.9%). Subjects with co-existing psychiatric disorders scored significantly Lower in multiple domains of SF-36 (mental component summary, general health, vitality and mental health). By multivariate Linear regression analysis, current psychiatric morbidities (Beta = -0.396, p = 0.002) and family history of psychiatric illness (Beta = -0.299, p = 0.015) were independent risk factors for poorer mental component summary in SF-36, while dyspepsia severity was the only independent risk factor for poorer physical component summary (Beta = -0.332, p = 0.027). Conclusions: Concomitant psychiatric disorders adversely affect HRQoL in FD patients. The use of GHQ-12 as a reliable screening tool for psychiatric disorders allows early intervention and may improve clinical outcomes of these patients.(J Neurogastroenterol Motil 2010;16:52-60)
( Y. Y. Wang ),( Z. B. Fu ),( K. L. Ng ),( C. C. Lam ),( A. K. N. Chan ),( K. F. Sze ),( W. K. R. Wong ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.6
Production of recombinant proteins by excretory expression has many advantages over intracellular expression in Escherichia coli. Hyperexpression of a secretory exoglucanase, Exg, of Cellulomonas fimi was previously shown to saturate the SecYEG pathway and result in dramatic cell death of E. coli. In this study, we demonstrated that overexpression of the PspA in the JM101(pM1VegGcexL-pspA) strain enhanced excretion of Exg to 1.65 U/ml using shake-flask cultivation, which was 80% higher than the highest yield previously obtained from the optimized JM101(pM1VegGcexL) strain. A much higher excreted Exg activity of 4.5 U/ml was further achieved with high cell density cultivation using rich media. Furthermore, we showed that the PspA overexpression strain enjoyed an elevated critical value (CV), which was defined as the largest quotient between the intracellular unprocessed precursor and its secreted mature counterpart that was still tolerable by the host cells prior to the onset of cell death, improving from the previously determined CV of 20/80 to the currently achieved CV of 45/55 for Exg. The results suggested that the PspA overexpression strain might tolerate a higher level of precursor Exg making use of the SecYEG pathway for secretion. The reduced lethal effect might be attributable to the overexpressed PspA, which was postulated to be able to reduce membrane depolarization and damage. Our findings introduce a novel strategy of the combined application of metabolic engineering and construct optimization to the attainment of the best possible E. coli producers for secretory/excretory production of recombinant proteins, using Exg as the model protein.
배열파력발전 플랫폼형상변화에 따른 운동응답특성에 관한 실험적 연구
박지용(J.Y. Park),남보우(B.W. Nam),신승호(S.H. Shin),박인보(I.B. Park),원영욱(Y.U. Won),오영재(Y.J. Oh),노찬(R. Chan),조세진(S.J. Cho) 한국해양환경·에너지학회 2018 한국해양환경공학회 학술대회논문집 Vol.2018 No.11
배열식 파력발전장치는 폭방향으로 긴 형상을 갖는 플랫폼에 다수의 로터를 배치하여 다양한 발전용량과 크기를 갖는 장치를 제작가능하다. 본 연구에서는 1MW 발전용량의 배열식파력 발전장치의 플랫폼형상에 대해 사이각 변화에 따른 운동응답특성의 변화를 실험적으로 분석하였다. 자유감쇠 실험을 통해 형상에 따른 고유주기를 검토하고, 150도, 120도, 90도로 사이각을 변화시키며, 정면과 측면의 입사파에서 주기와 파고에 따른 운동을 비교하였다. 이를 통해, 발전성능과 구조안전성의 측면에서 형상제어의 필요성을 확인하였으며, 추후 로터운동을 고려한 플랫폼 운동성능평가를 수행하려 한다. In the arrayed-buoy wave energy converter, a plurality of rotors is disposed on a platform having a long shape in the width direction, thereby making it possible to construct a device having various power generation capacities and sizes. In this study, the change of wave response according to the included angle was experimentally analyzed with respect to the 1 MW arrayed-buoy wave energy converter. The natural period of the platform was analyzed by free decay model test and the wave motions are measured and compared according to the included angle of 150°, 120° and 90° under the head sea and beam sea wave conditions. Through this study, the necessity of shape control in terms of power generation performance and structural safety was confirmed and we will perform platform motion performance evaluation considering rotor motion in the future.
( Stacey C. Y. Li ),( Catherine W. C. Chan ),( Janet K. Y. Chan ) 한국폐기물자원순환학회 2022 ISSE 초록집 Vol.2022 No.-
Mobile phones have become one of the most indispensable items of our daily life. People normally have the practice of reselling their old phones or other electronic devices because of their high value. However, the USB cables normally come with these gadgets are always forgotten. As the USB cables are made of plastics and metals, it would be a waste of resources if they were sent to the landfill directly. There is a lack of data and studies regarding the amount of USB cable waste, and people’s handling and disposing habits of them in Hong Kong. This action-cum-research project, namely “Off-lines”, therefore aims to raise people’s awareness on e-waste beginning with a type of waste that everyone has, that is USB cable, and to fill in the research gap on people’s awareness and knowledge on this kind of e-waste. One hundred and fifty collection points were set up all over Hong Kong by this project and successfully collected over 7,700 unwanted cables from the public. This project also conducted a questionnaire survey from February 2022 to May 2022 and received 457 valid responses from the public. The results of the questionnaires show that nearly 70% of respondents do not know USB cables can be recycled. The three major reasons for not recycling USB cable are: 1) Not knowing any collection points (71%); 2) Lack of knowledge on USB cable recycling (67%); and 3) Inconvenient and insufficient collection points (67%). Upcycling workshops were also organised not only to provide a chance for the participants to have hands-on experience on making knots with USB cables, but also to inspire them to think out of the box and give any unwanted item a second life. Feedback from the public and also the business sector found the project very meaningful and successfully heightened the public awareness on e-waste issues. Collaboration with green groups and other partnering organisations should be extended to provide wider and immersive networks for collecting unwanted USB cables or other cables.