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      • A Process Model for Deciding Elderly Care

        Suzuki, Tomomichi,Imai, Takayuki,Yaezawa, Toru,Wakasugi, Tadahiro,Iizuka, Yoshinori,Ojima, Yoshikazu 한국품질경영학회 2002 The Asian Journal on Quality Vol.3 No.1

        Care to an older person is provided based on the care plan that was made by a care manager. Therefore, to improve the quality of elderly care, the quality of the care plan must first be improved. Care managers make care plans considering the physical and mental attributes of the elderly. But, as matters stand, these plans are based on the experience of care managers. Therefore, a framework that can support making appropriate care plans is called for. In order to make appropriate care plans, it is necessary to clarify the relation between the attributes of the elderly and the care that should be provided. In this paper, data from a large-scale investigation of the actual elderly care are analyzed and a process model for deciding the care is proposed. The model provides the necessary basis for what factors must be considered and how the care should be determined.

      • KCI등재

        MBE Growth of ZnSe Films on Lattice-Matched InxGa1-xAs Substrates

        Takashi KARITA,Kazuhiko Suzuki,Takayuki SAWADA,Kazuaki IMAI,Satoru SETO 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.1

        Raman scatering of ZnSe layers grown on nearly latice matched InxGa1-xAs substrates (x = 0 -0.092) by using molecular beam epitaxy (MBE) have ben investigated. The Raman shift of the ZnSe longitudinal optical (LO) phonon stays nearly constant while the line width Γ increases with increasing indium molar fraction of the substrates. The results are analyzed based on the two-parameter spatial corelation model. The intrinsic line width of ZnSe LO is found to depend strongly on the spatial corelation length of the substrate.

      • KCI등재

        Early diagnosis of malignant-transformed ovarian mature cystic teratoma: fat-suppressed MRI findings

        Hiroshi Takagi,Satoshi Ichigo,Takayuki Murase,Tsuneko Ikeda,Atsushi Imai 대한부인종양학회 2012 Journal of Gynecologic Oncology Vol.23 No.2

        The most common form of malignant transformation developing from a mature cystic teratoma is squamous cell carcinoma,representing 80% of malignant transformations, while adenocarcinoma accounts for approximately 5%. Because of this rarity,few reports exist of preoperative diagnosis of this tumor by magnetic resonance imaging, in particular with fat suppression techniques. Here, we report magnetic resonance imaging findings and clinical features of a 79-year-old woman with mucinous adenocarcinoma arising from a mature cystic teratoma (measuring 5×6 cm), classified as surgical stage IA. Because of the poor prognosis of malignant transformation, when mature cystic teratomas are detected (even smaller than 5 cm tumor size)in postmenopausal women, serum tumor marker carcinoembryonic antigen levels and fat-suppressed magnetic resonance imaging may be potential indicators of malignant transformation.

      • KCI등재

        Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease

        Shigeki Bamba,Osamu Inatomi,Atsushi Nishida,Masashi Ohno,Takayuki Imai,Kenichiro Takahashi,Yuji Naito,Junichi Iwamoto,Akira Honda,Naohiro Inohara,Akira Andoh 대한장연구학회 2022 Intestinal Research Vol.20 No.3

        Background/Aims: Crosstalk between the gut microbiota and bile acid plays an important role in the pathogenesis of gastrointestinal disorders. We investigated the relationship between microbial structure and bile acid metabolism in the ileal mucosa of Crohn’s disease (CD).Methods: Twelve non-CD controls and 38 CD patients in clinical remission were enrolled. Samples were collected from the distal ileum under balloon-assisted enteroscopy. Bile acid composition was analyzed by liquid chromatography-mass spectrometry. The gut microbiota was analyzed by 16S rRNA gene sequencing.Results: The Shannon evenness index was significantly lower in endoscopically active lesions than in non-CD controls. β-Diversity, evaluated by the UniFrac metric, revealed a significant difference between the active lesions and non-CD controls (<i>P</i>=0.039). The relative abundance of <i>Escherichia</i> was significantly higher and that of <i>Faecalibacterium</i> and <i>Roseburia</i> was significantly lower in CD samples than in non-CD controls. The increased abundance of <i>Escherichia</i> was more prominent in active lesions than in inactive lesions. The proportion of conjugated bile acids was significantly higher in CD patients than in non-CD controls, but there was no difference in the proportion of primary or secondary bile acids. The genera <i>Escherichia</i> and <i>Lactobacillus</i> were positively correlated with the proportion of conjugated bile acids. On the other hand, <i>Roseburia</i>, <i>Intestinibacter</i>, and <i>Faecalibacterium</i> were negatively correlated with the proportion of conjugated bile acids.Conclusions: Mucosa-associated dysbiosis and the alteration of bile acid composition were identified in the ileum of CD patients. These may play a role in the pathophysiology of ileal lesions in CD patients.

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        Prototype single-balloon enteroscopy with passive bending and high force transmission improves depth of insertion in the small intestine

        ( Yasuhiro Morita ),( Shigeki Bamba ),( Osamu Inatomi ),( Kenichiro Takahashi ),( Takayuki Imai ),( Masaki Murata ),( Masashi Ohno ),( Masaya Sasaki ),( Tomoyuki Tsujikawa ),( Akira Andoh ) 대한장연구학회 2020 Intestinal Research Vol.18 No.2

        Background/Aims: We retrospectively analyzed Crohn’s disease (CD) patients with small intestinal strictures who underwent single-balloon enteroscopy (SBE) to ascertain whether prototype SBEs with a passive bending mechanism and high force transmission insertion tube had better insertability in the small intestine than a conventional SBE. Methods: Among 253 CD patients who underwent SBE, we identified 94 CD patients who had undergone attempted endoscopic balloon dilatation (EBD) for small intestinal stenosis for inclusion in this study. We analyzed whether the type of scope used for their initial procedure affected the cumulative surgery-free rate. For the insertability analysis, patients who underwent SBE at least twice were divided into 3 groups according to the type of scope used: conventional SBE only, prototype SBE only, and both conventional and prototype SBEs. For each group, depth of insertion, procedure time, and number of EBDs were compared in the same patient at different time points. Results: The success rate of EBD was 88.3%. The 5- and 10-year cumulative surgery-free rate was 75.7% and 72.8%, respectively. Cox regression analysis indicated that the factors contributing to surgery were long stricture (≥2 cm), EBD failure, and elevated Crohn’s Disease Activity Index, but not the type of scope used for EBD. The prototype SBEs significantly improved the depth of insertion (P=0.03, Wilcoxon’s signed-rank test). Conclusions: In CD patients with small intestinal stenosis, the prototype SBEs with a passive bending mechanism and high force transmission insertion tube did not improve long-term EBD outcome but did improve deep insertability. (Clinical Trial Registration No. UMIN000037102) (Intest Res 2020;18:229-237)

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