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      • KCI등재

        Publication of the Japan Bible Society Interconfessional Version

        Junichi Iwamoto 대한성서공회 2019 성경원문연구 Vol.0 No.44

        The Japan Bible Society Interconfessional Version (=JIV) was published by Japan Bible Society (JBS) in December 2018. It is the second Japanese interconfessional version, translated from the biblical source texts. The first one was the New Interconfessional Version (=JNIV) published in 1987. There were some problems in JNIV. The biggest problem was a change of the translation theory during the translation process where the principle changed from dynamic equivalence to formal correspondence. Because of this change, there remained some confusion of two translation theories in JNIV. JBS adopted skopos theory as the basis of its JIV Bible translation. The skopos of JIV was set as “to seek stylistically refined and beautiful Japanese translation suitable for the reading in the worship”. This skopos was clearly shown in the preface of the Guideline for the Translation for JIV in 2009. The New Translation Project (=NTP) started in 2010 and ended in 2017. There were 148 persons ― 62 translators, 43 editors, 20 external monitors, and 23 advisors ― engaged in the work. The characteristics of JIV are especially marked by the contribution of female members and the changing the translation of two important biblical terms.

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        Relationship between the gut microbiota and bile acid composition in the ileal mucosa of Crohn’s disease

        Shigeki Bamba,Osamu Inatomi,Atsushi Nishida,Masashi Ohno,Takayuki Imai,Kenichiro Takahashi,Yuji Naito,Junichi Iwamoto,Akira Honda,Naohiro Inohara,Akira Andoh 대한장연구학회 2022 Intestinal Research Vol.20 No.3

        Background/Aims: Crosstalk between the gut microbiota and bile acid plays an important role in the pathogenesis of gastrointestinal disorders. We investigated the relationship between microbial structure and bile acid metabolism in the ileal mucosa of Crohn’s disease (CD).Methods: Twelve non-CD controls and 38 CD patients in clinical remission were enrolled. Samples were collected from the distal ileum under balloon-assisted enteroscopy. Bile acid composition was analyzed by liquid chromatography-mass spectrometry. The gut microbiota was analyzed by 16S rRNA gene sequencing.Results: The Shannon evenness index was significantly lower in endoscopically active lesions than in non-CD controls. β-Diversity, evaluated by the UniFrac metric, revealed a significant difference between the active lesions and non-CD controls (<i>P</i>=0.039). The relative abundance of <i>Escherichia</i> was significantly higher and that of <i>Faecalibacterium</i> and <i>Roseburia</i> was significantly lower in CD samples than in non-CD controls. The increased abundance of <i>Escherichia</i> was more prominent in active lesions than in inactive lesions. The proportion of conjugated bile acids was significantly higher in CD patients than in non-CD controls, but there was no difference in the proportion of primary or secondary bile acids. The genera <i>Escherichia</i> and <i>Lactobacillus</i> were positively correlated with the proportion of conjugated bile acids. On the other hand, <i>Roseburia</i>, <i>Intestinibacter</i>, and <i>Faecalibacterium</i> were negatively correlated with the proportion of conjugated bile acids.Conclusions: Mucosa-associated dysbiosis and the alteration of bile acid composition were identified in the ileum of CD patients. These may play a role in the pathophysiology of ileal lesions in CD patients.

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