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A Novel Technique for Retrieval of a Drug-Eluting Stent After Catheter Break and Stent Loss
Sunil P. Wani,나승운,박지영,Kanhaiya L Poddar,Lin Wang,Sureshkumar Ramasamy,문지미,류상렬,신승용,최운정,박창규,서홍석,오동주,최철웅,임홍의 대한심장학회 2010 Korean Circulation Journal Vol.40 No.8
Break of a stent delivery catheter and subsequent stent loss (SL) has been a rare event in the drug-eluting stent (DES) era. We here report a case of successful retrieval of a stent after a break if the delivery catheter and SL from a balloon catheter at a culprit lesion. We finally resolved this situation using a simple balloon technique for both the broken stent catheter inside of the guide catheter and the unexpanded stent in the culprit lesion. Thus balloons are an important weapon in our armamentarium in the cardiac catheterization laboratory for urgent retrieval of a lost stent. Their apt use definitely allowed our patient to avoid undergoing emergency cardiovascular thoracic surgery.
Medium constituents mediated engineering for size and shape tuning of gold nanocrystallites
Anil K. Suresh,Veena Vijay,Bahrudeen S. Hameed,Sureshkumar Ramasamy,Natarajan Sakthivel 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.51 No.-
The current investigation introduces the utilization of cell culture mediums as a novel source for the oneplotsynthesis as well as stabilization of metal nanoparticles. By varying the medium constituents wecould control the size and shape distributions of the gold nanoparticles. Nanospheres of diameter24 6 nm and 19 5 nm were produced using DMEM and M199 mediums respectively, nanoneedles of150 50 nm using RPMI medium and nanoflowers of 60 25 nm using IMDM medium, with an overallyield of 91 2%. A remarkable decrease in the reaction duration (<3 min) was noted, irrespective of thegrowth mediums used. Fourier transform infrared spectroscopy and zeta potential measurementsrevealed them to have a common protenacious encapping agent with different overall surface charges of23 3,211,24 2, and20 1 mV for Au@DMEM, Au@RPMI, Au@IMDM andAu@M199 respectively. X-ray diffraction confirmed the purity and crystallinity of the particles withBragg peaks at (111), (200), (220) and (311) for gold nanocrystals. This approach could lead to the creativeutilization of novel eco-friendly sources for the production and size/shape control of nanoparticles. Moreover, the adopted methodology is absolutely green, robust and facile, offering new insights forsustainable synthesis for various biomedical and engineering applications.
나승운,Kang-Yin Chen,오동주,Yong-Jian Li,Zhe Jin,Kanhaiya Lal Poddar,Sureshkumar Ramasamy,Yoshiyasu Minami,Amro Elnagar,최병걸,Sang Pyo Hong,Byoung Won Cheon,Sang Ki Moon,Sung Il Im,Sun Won Kim,나진오,홍영준,임홍의,김진원 대한심장학회 2012 Korean Circulation Journal Vol.42 No.6
Background and Objectives: Although the use of heterogeneous overlapping drug-eluting stents (DES) is not uncommon in clinical practice, whether the implantation sequences of heterogeneous DES will influence the endothelialization or arterial responses differently remains unclear. Materials and Methods: Twenty-one rabbits were randomized to receive overlapping stents in the iliac artery for 3 months {distal siroli-mus-eluting stent (SES, Cypher TM )+proximal paclitaxel-eluting stent (PES, Taxus TM ) (C+T, n=7), distal Taxus+proximal Cypher (T+C, n=7) and bare metal stent (BMS)+BMS (B+B, n=7)}. Endothelial function was evaluated by the acetylcholine provocation test during follow-up an-giography. Histopathological changes in proximal, overlapped, and distal stented segments were evaluated. Results: Although the overall angiographic outcomes were comparable, late loss (mm) in the distal stented segment was higher in the B+B (0.39±0.07) and C+T (0.40±0.20) than that in the T+C (0.06±0.02) group (p<0.001). The incidence of acetylcholine-induced spasm was higher in the DES groups compared with BMS, regardless of the implantation sequences (85.7% in C+T vs. 14.3% in B+B vs. 71.4% in T+C,p=0.017). Notably, only the distal Cypher implantation group (C+T) had three cases of stent fracture. A histopathological analysis showed that despite similar arterial injury scores, Taxus and Cypher stents had higher inflammatory reactions at the overlapped and distal segments compared with those of BMS. Conclusion: Despite similar arterial injury, higher inflammatory reactions were observed in overlapping DES segments regardless of the im -plantation sequence compared with that of BMS. Moreover, DES was associated with impaired endothelial function on the adjacent non-stented segments.